-
1
-
-
0023604799
-
Chloramphenicol, erythromycin, carbomycin and vernamycin B protect overlapping sites in the peptidyl transferase region of 23S ribosomal RNA
-
Moazed D., and Noller H.F. Chloramphenicol, erythromycin, carbomycin and vernamycin B protect overlapping sites in the peptidyl transferase region of 23S ribosomal RNA. Biochimie 69 (1987) 879-884
-
(1987)
Biochimie
, vol.69
, pp. 879-884
-
-
Moazed, D.1
Noller, H.F.2
-
2
-
-
0343417099
-
Erythromycin resistance due to mutation in a ribosomal RNA operon of Escherichia coli
-
Sigmund C.D., and Morgan E.A. Erythromycin resistance due to mutation in a ribosomal RNA operon of Escherichia coli. Proc Natl Acad Sci U S A 79 (1982) 5602-5606
-
(1982)
Proc Natl Acad Sci U S A
, vol.79
, pp. 5602-5606
-
-
Sigmund, C.D.1
Morgan, E.A.2
-
3
-
-
0023587832
-
A plasmid-coded and site-directed mutation in Escherichia coli 23S RNA that confers resistance to erythromycin: implications for the mechanism of action of erythromycin
-
Vester B., and Garrett R.A. A plasmid-coded and site-directed mutation in Escherichia coli 23S RNA that confers resistance to erythromycin: implications for the mechanism of action of erythromycin. Biochimie 69 (1987) 891-900
-
(1987)
Biochimie
, vol.69
, pp. 891-900
-
-
Vester, B.1
Garrett, R.A.2
-
4
-
-
0035160878
-
Macrolide resistance conferred by base substitutions in 23S rRNA
-
Vester B., and Douthwaite S. Macrolide resistance conferred by base substitutions in 23S rRNA. Antimicrob Agents Chemother 45 (2001) 1-12
-
(2001)
Antimicrob Agents Chemother
, vol.45
, pp. 1-12
-
-
Vester, B.1
Douthwaite, S.2
-
5
-
-
0032950956
-
The macrolide-ketolide antibiotic binding site is formed by structures in domains II and V of 23S ribosomal RNA
-
Hansen L.H., Mauvais P., and Douthwaite S. The macrolide-ketolide antibiotic binding site is formed by structures in domains II and V of 23S ribosomal RNA. Mol Microbiol 31 (1999) 623-632
-
(1999)
Mol Microbiol
, vol.31
, pp. 623-632
-
-
Hansen, L.H.1
Mauvais, P.2
Douthwaite, S.3
-
6
-
-
0032904341
-
A ketolide resistance mutation in domain II of 23S rRNA reveals proximity of hairpin 35 to the peptidyl transferase centre
-
Xiong L., Shah S., Mauvais P., and Mankin A.S. A ketolide resistance mutation in domain II of 23S rRNA reveals proximity of hairpin 35 to the peptidyl transferase centre. Mol Microbiol 31 (1999) 633-639
-
(1999)
Mol Microbiol
, vol.31
, pp. 633-639
-
-
Xiong, L.1
Shah, S.2
Mauvais, P.3
Mankin, A.S.4
-
7
-
-
0037334850
-
Structural basis for the antibiotic activity of ketolides and azalides
-
Schlunzen F., Harms J.M., Franceschi F., Hansen H.A., Bartels H., Zarivach R., and Yonath A. Structural basis for the antibiotic activity of ketolides and azalides. Structure 11 (2003) 329-338
-
(2003)
Structure
, vol.11
, pp. 329-338
-
-
Schlunzen, F.1
Harms, J.M.2
Franceschi, F.3
Hansen, H.A.4
Bartels, H.5
Zarivach, R.6
Yonath, A.7
-
8
-
-
0035950132
-
Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria
-
The first crystallographic structure of macrolide-ribosome complexes.
-
Schlunzen F., Zarivach R., Harms J., Bashan A., Tocilj A., Albrecht R., Yonath A., and Franceschi F. Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria. Nature 413 (2001) 814-821. The first crystallographic structure of macrolide-ribosome complexes.
-
(2001)
Nature
, vol.413
, pp. 814-821
-
-
Schlunzen, F.1
Zarivach, R.2
Harms, J.3
Bashan, A.4
Tocilj, A.5
Albrecht, R.6
Yonath, A.7
Franceschi, F.8
-
9
-
-
0036342198
-
The structures of four macrolide antibiotics bound to the large ribosomal subunit
-
Hansen J.L., Ippolito J.A., Ban N., Nissen P., Moore P.B., and Steitz T.A. The structures of four macrolide antibiotics bound to the large ribosomal subunit. Mol Cell 10 (2002) 117-128
-
(2002)
Mol Cell
, vol.10
, pp. 117-128
-
-
Hansen, J.L.1
Ippolito, J.A.2
Ban, N.3
Nissen, P.4
Moore, P.B.5
Steitz, T.A.6
-
10
-
-
17444421169
-
Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance
-
Currently, the highest resolution structures of macrolide antibiotics complexed to the ribosomal subunit.
-
Tu D., Blaha G., Moore P.B., and Steitz T.A. Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance. Cell 121 (2005) 257-270. Currently, the highest resolution structures of macrolide antibiotics complexed to the ribosomal subunit.
-
(2005)
Cell
, vol.121
, pp. 257-270
-
-
Tu, D.1
Blaha, G.2
Moore, P.B.3
Steitz, T.A.4
-
11
-
-
0028963496
-
Erythromycin resistance by ribosome modification
-
Weisblum B. Erythromycin resistance by ribosome modification. Antimicrob Agents Chemother 39 (1995) 577-585
-
(1995)
Antimicrob Agents Chemother
, vol.39
, pp. 577-585
-
-
Weisblum, B.1
-
12
-
-
0038492422
-
Structural insight into the antibiotic action of telithromycin against resistant mutants
-
Berisio R., Harms J., Schluenzen F., Zarivach R., Hansen H.A., Fucini P., and Yonath A. Structural insight into the antibiotic action of telithromycin against resistant mutants. J Bacteriol 185 (2003) 4276-4279
-
(2003)
J Bacteriol
, vol.185
, pp. 4276-4279
-
-
Berisio, R.1
Harms, J.2
Schluenzen, F.3
Zarivach, R.4
Hansen, H.A.5
Fucini, P.6
Yonath, A.7
-
13
-
-
0034406527
-
Inhibition of the ribosomal peptidyl transferase reaction by the mycarose moiety of the antibiotics carbomycin, spiramycin and tylosin
-
Poulsen S.M., Kofoed C., and Vester B. Inhibition of the ribosomal peptidyl transferase reaction by the mycarose moiety of the antibiotics carbomycin, spiramycin and tylosin. J Mol Biol 304 (2000) 471-481
-
(2000)
J Mol Biol
, vol.304
, pp. 471-481
-
-
Poulsen, S.M.1
Kofoed, C.2
Vester, B.3
-
14
-
-
0015239582
-
Effects of macrolides on peptide-bond formation and translocation
-
Mao J.C.-H., and Robishaw E.E. Effects of macrolides on peptide-bond formation and translocation. Biochemistry 10 (1971) 2054-2061
-
(1971)
Biochemistry
, vol.10
, pp. 2054-2061
-
-
Mao, J.C.-H.1
Robishaw, E.E.2
-
15
-
-
0020322533
-
Erythromycin, carbomycin, and spiramycin inhibit protein synthesis by stimulating the dissociation of peptidyl-tRNA from ribosomes
-
Menninger J.R., and Otto D.P. Erythromycin, carbomycin, and spiramycin inhibit protein synthesis by stimulating the dissociation of peptidyl-tRNA from ribosomes. Antimicrob Agents Chemother 21 (1982) 810-818
-
(1982)
Antimicrob Agents Chemother
, vol.21
, pp. 810-818
-
-
Menninger, J.R.1
Otto, D.P.2
-
16
-
-
0016710554
-
Release of (oligo) peptidyl-tRNA from ribosomes by erythromycin A
-
Otaka T., and Kaji A. Release of (oligo) peptidyl-tRNA from ribosomes by erythromycin A. Proc Natl Acad Sci U S A 72 (1975) 2649-2652
-
(1975)
Proc Natl Acad Sci U S A
, vol.72
, pp. 2649-2652
-
-
Otaka, T.1
Kaji, A.2
-
17
-
-
0038690158
-
The mechanism of action of macrolides, lincosamides and streptogramin B reveals the nascent peptide exit path in the ribosome
-
The accurate characterization of peptidyl-tRNAs dissociated from the ribosome because of macrolide-induced drop-off.
-
Tenson T., Lovmar M., and Ehrenberg M. The mechanism of action of macrolides, lincosamides and streptogramin B reveals the nascent peptide exit path in the ribosome. J Mol Biol 330 (2003) 1005-1014. The accurate characterization of peptidyl-tRNAs dissociated from the ribosome because of macrolide-induced drop-off.
-
(2003)
J Mol Biol
, vol.330
, pp. 1005-1014
-
-
Tenson, T.1
Lovmar, M.2
Ehrenberg, M.3
-
18
-
-
0029157585
-
Macrolide antibiotics inhibit 50S ribosomal subunit assembly in Bacillus subtilis and Staphylococcus aureus
-
Champney W.S., and Burdine R. Macrolide antibiotics inhibit 50S ribosomal subunit assembly in Bacillus subtilis and Staphylococcus aureus. Antimicrob Agents Chemother 39 (1995) 2141-2144
-
(1995)
Antimicrob Agents Chemother
, vol.39
, pp. 2141-2144
-
-
Champney, W.S.1
Burdine, R.2
-
19
-
-
0034115717
-
Macrolide-ketolide inhibition of MLS-resistant ribosomes is improved by alternative drug interaction with domain II of 23S rRNA
-
Douthwaite S., Hansen L.H., and Mauvais P. Macrolide-ketolide inhibition of MLS-resistant ribosomes is improved by alternative drug interaction with domain II of 23S rRNA. Mol Microbiol 36 (2000) 183-193
-
(2000)
Mol Microbiol
, vol.36
, pp. 183-193
-
-
Douthwaite, S.1
Hansen, L.H.2
Mauvais, P.3
-
20
-
-
11244307407
-
Binding site of the bridged macrolides in the Escherichia coli ribosome
-
Xiong L., Korkhin Y., and Mankin A.S. Binding site of the bridged macrolides in the Escherichia coli ribosome. Antimicrob Agents Chemother 49 (2005) 281-288
-
(2005)
Antimicrob Agents Chemother
, vol.49
, pp. 281-288
-
-
Xiong, L.1
Korkhin, Y.2
Mankin, A.S.3
-
21
-
-
17044425907
-
23S rRNA base pair 2057-2611 determines ketolide susceptibility and fitness cost of the macrolide resistance mutation 2058A→G
-
Pfister P., Corti N., Hobbie S., Bruell C., Zarivach R., Yonath A., and Bottger E.C. 23S rRNA base pair 2057-2611 determines ketolide susceptibility and fitness cost of the macrolide resistance mutation 2058A→G. Proc Natl Acad Sci U S A 102 (2005) 5180-5185
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 5180-5185
-
-
Pfister, P.1
Corti, N.2
Hobbie, S.3
Bruell, C.4
Zarivach, R.5
Yonath, A.6
Bottger, E.C.7
-
22
-
-
40449123425
-
Mutation from guanine to adenine in 25S rRNA at the position equivalent to E. coli A2058 does not confer erythromycin sensitivity in Sacchromyces cerevisae
-
Bommakanti A.S., Lindahl L., and Zengel J.M. Mutation from guanine to adenine in 25S rRNA at the position equivalent to E. coli A2058 does not confer erythromycin sensitivity in Sacchromyces cerevisae. RNA 14 (2008) 460-464
-
(2008)
RNA
, vol.14
, pp. 460-464
-
-
Bommakanti, A.S.1
Lindahl, L.2
Zengel, J.M.3
-
23
-
-
0024602563
-
ermC leader peptide. Amino acid sequence critical for induction by translational attenuation
-
Mayford M., and Weisblum B. ermC leader peptide. Amino acid sequence critical for induction by translational attenuation. J Mol Biol 206 (1989) 69-79
-
(1989)
J Mol Biol
, vol.206
, pp. 69-79
-
-
Mayford, M.1
Weisblum, B.2
-
24
-
-
43049089746
-
Molecular mechanism of drug-dependent ribosome stalling
-
Vazquez-Laslop N., Thum C., and Mankin A.S. Molecular mechanism of drug-dependent ribosome stalling. Mol Cell 30 (2008) 190-202
-
(2008)
Mol Cell
, vol.30
, pp. 190-202
-
-
Vazquez-Laslop, N.1
Thum, C.2
Mankin, A.S.3
-
25
-
-
0033014076
-
Erythromycin resistance mutations in ribosomal proteins L22 and L4 perturb the higher order structure of 23 S ribosomal RNA
-
Gregory S.T., and Dahlberg A.E. Erythromycin resistance mutations in ribosomal proteins L22 and L4 perturb the higher order structure of 23 S ribosomal RNA. J Mol Biol 289 (1999) 827-834
-
(1999)
J Mol Biol
, vol.289
, pp. 827-834
-
-
Gregory, S.T.1
Dahlberg, A.E.2
-
26
-
-
0034885664
-
The polypeptide tunnel system in the ribosome and its gating in erythromycin resistance mutants of L4 and L22
-
Gabashvili I.S., Gregory S.T., Valle M., Grassucci R., Worbs M., Wahl M.C., Dahlberg A.E., and Frank J. The polypeptide tunnel system in the ribosome and its gating in erythromycin resistance mutants of L4 and L22. Mol Cell 8 (2001) 181-188
-
(2001)
Mol Cell
, vol.8
, pp. 181-188
-
-
Gabashvili, I.S.1
Gregory, S.T.2
Valle, M.3
Grassucci, R.4
Worbs, M.5
Wahl, M.C.6
Dahlberg, A.E.7
Frank, J.8
-
27
-
-
33645465733
-
Antibiotics and the ribosome
-
Tenson T., and Mankin A.S. Antibiotics and the ribosome. Mol Microbiol 59 (2006) 1664-1677
-
(2006)
Mol Microbiol
, vol.59
, pp. 1664-1677
-
-
Tenson, T.1
Mankin, A.S.2
-
28
-
-
0028914553
-
Insights into erythromycin action from studies of its activity as inducer of resistance
-
Weisblum B. Insights into erythromycin action from studies of its activity as inducer of resistance. Antimicrob Agents Chemother 39 (1995) 797-805
-
(1995)
Antimicrob Agents Chemother
, vol.39
, pp. 797-805
-
-
Weisblum, B.1
-
29
-
-
33845987038
-
ErmK leader peptide: amino acid sequence critical for induction by erythromycin
-
Kwon A.R., Min Y.H., Yoon E.J., Kim J.A., Shim M.J., and Choi E.C. ErmK leader peptide: amino acid sequence critical for induction by erythromycin. Arch Pharm Res 29 (2006) 1154-1157
-
(2006)
Arch Pharm Res
, vol.29
, pp. 1154-1157
-
-
Kwon, A.R.1
Min, Y.H.2
Yoon, E.J.3
Kim, J.A.4
Shim, M.J.5
Choi, E.C.6
-
30
-
-
0029953161
-
A functional peptide encoded in the Escherichia coli 23S Rrna
-
Tenson T., DeBlasio A., and Mankin A. A functional peptide encoded in the Escherichia coli 23S Rrna. Proc Natl Acad Sci U S A 93 (1996) 5641-5646
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 5641-5646
-
-
Tenson, T.1
DeBlasio, A.2
Mankin, A.3
-
31
-
-
0032493758
-
Ketolide resistance conferred by short peptides
-
Tripathi S., Kloss P.S., and Mankin A.S. Ketolide resistance conferred by short peptides. J Biol Chem 273 (1998) 20073-20077
-
(1998)
J Biol Chem
, vol.273
, pp. 20073-20077
-
-
Tripathi, S.1
Kloss, P.S.2
Mankin, A.S.3
-
32
-
-
33646574678
-
The molecular mechanism of peptide-mediated erythromycin resistance
-
Lovmar M., Nilsson K., Vimberg V., Tenson T., Nervall M., and Ehrenberg M. The molecular mechanism of peptide-mediated erythromycin resistance. J Biol Chem 281 (2006) 6742-6750
-
(2006)
J Biol Chem
, vol.281
, pp. 6742-6750
-
-
Lovmar, M.1
Nilsson, K.2
Vimberg, V.3
Tenson, T.4
Nervall, M.5
Ehrenberg, M.6
-
33
-
-
0030748654
-
Erythromycin resistance peptides selected from random peptide libraries
-
Tenson T., Xiong L., Kloss P., and Mankin A.S. Erythromycin resistance peptides selected from random peptide libraries. J Biol Chem 272 (1997) 17425-17430
-
(1997)
J Biol Chem
, vol.272
, pp. 17425-17430
-
-
Tenson, T.1
Xiong, L.2
Kloss, P.3
Mankin, A.S.4
-
34
-
-
11144238888
-
Kinetics of macrolide action: the josamycin and erythromycin cases
-
Lovmar M., Tenson T., and Ehrenberg M. Kinetics of macrolide action: the josamycin and erythromycin cases. J Biol Chem 279 (2004) 53506-53515
-
(2004)
J Biol Chem
, vol.279
, pp. 53506-53515
-
-
Lovmar, M.1
Tenson, T.2
Ehrenberg, M.3
-
35
-
-
37449027381
-
Transient erythromycin resistance phenotype associated with peptidyl-tRNA drop-off on early UGG and GGG codons
-
Macvanin M., Gonzalez de Valdivia E.I., Ardell D.H., and Isaksson L.A. Transient erythromycin resistance phenotype associated with peptidyl-tRNA drop-off on early UGG and GGG codons. J Bacteriol 189 (2007) 8993-9000
-
(2007)
J Bacteriol
, vol.189
, pp. 8993-9000
-
-
Macvanin, M.1
Gonzalez de Valdivia, E.I.2
Ardell, D.H.3
Isaksson, L.A.4
-
36
-
-
0037399205
-
The chemistry of protein synthesis and voyage through the ribosomal tunnel
-
Jenni S., and Ban N. The chemistry of protein synthesis and voyage through the ribosomal tunnel. Curr Opin Struct Biol 13 (2003) 212-219
-
(2003)
Curr Opin Struct Biol
, vol.13
, pp. 212-219
-
-
Jenni, S.1
Ban, N.2
|