Assessment of metalloproteinase inhibitors clodronate and doxycycline in the neutralization of hemorrhage and coagulopathy induced by Bothrops asper snake venom

Toxicon

Volumn 52, Issue 7, 2008, Pages 754-759

  Rucavado, Alexandra ^a   Henríquez, Mónica ^a   García, Jonielle ^a   Gutiérrez, José María ^a  

^a UNIVERSIDAD DE COSTA RICA   (Costa Rica)

Author keywords

Bothrops asper; Clodronate; Coagulopathy; Doxycycline; Hemorrhage; Metalloproteinases; Snake venom

Indexed keywords

CLODRONIC ACID; DOXYCYCLINE; METALLOPROTEINASE INHIBITOR; SNAKE VENOM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLEEDING; BLOOD CLOTTING DISORDER; BOTHROPS ASPER; CHELATION; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; DRUG SCREENING; ENVENOMATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; SNAKE;

ANIMALS; BLOOD COAGULATION; BOTHROPS; CLODRONIC ACID; CROTALID VENOMS; DOXYCYCLINE; ENZYME INHIBITORS; HEMORRHAGE; HUMANS; INHIBITORY CONCENTRATION 50; METALLOPROTEASES; MICE; MICE, INBRED STRAINS;

BOTHROPS ASPER; VIPERIDAE;

EID: 55049092141     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2008.08.009     Document Type: Article

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