A novel P-I class metalloproteinase with broad substrate-cleaving activity, agkislysin, from Agkistrodon acutus venom

Biochemical and Biophysical Research Communications

Volumn 324, Issue 1, 2004, Pages 224-230

  Wang, Wen Jeng ^a   Shih, Chun Ho ^a   Huang, Tur Fu ^b  

^a CHANG GUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Agkislysin; Agkistrodon acutus; Metalloproteinase; Platelet aggregation; Proteolytic activity

Indexed keywords

AGKISLYSIN; CHELATING AGENT; COLLAGEN TYPE 4; FIBRONECTIN; METALLOPROTEINASE; PROTHROMBIN; SERINE PROTEINASE INHIBITOR; SNAKE VENOM; UNCLASSIFIED DRUG; VON WILLEBRAND FACTOR;

AGKISTRODON ACUTUS; ARTICLE; COLUMN CHROMATOGRAPHY; DRUG ISOLATION; DRUG MECHANISM; DRUG POTENCY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME MECHANISM; ENZYME PURIFICATION; ENZYME SUBSTRATE; ENZYME SUBUNIT; HYDROLYSIS; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN ANALYSIS; SNAKE; THROMBOCYTE AGGREGATION;

AGKISTRODON; ANIMALS; CASEINS; COLLAGEN TYPE IV; CROTALID VENOMS; FIBRINOGEN; HUMANS; METALLOPROTEASES; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; PROTHROMBIN; RISTOCETIN;

AGKISTRODON; DEINAGKISTRODON ACUTUS;

EID: 4744363468     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.09.031     Document Type: Article

References (25)

1. T. Matsui, Y. Fujimra, and K. Titani Snake vemon proteases affecting hemostasis and thrombosis Biochim. Biophys. Acta 1477 2000 146 156
2. S. Braud, C. Bon, and A. Wisner Snake venom proteins acting on hemostasis Biochimie 82 2000 851 859
3. I.H. Tsai, Y.M. Wang, T.Y. Chiang, Y.L. Chen, and R.J. Huang Purification, cloning and sequence analyses for pro-metalloprotease-disintegrin variants from Deinagkistrodon acutus venom and subclassification of the small venom metalloproteases Eur. J. Biochem. 267 2000 1359 1367
4. 5-proteinase) and characterization of hemorrhagic toxins from the venom of the hundred-pace snake (Agkistrodon acutus) Toxicon 22 1984 451 461
5. 1-proteinase from the venom of Deinagkistrodon acutus (hundred-pace snake) from Taiwan Biol. Pharm. Bull. 18 1995 631 633
6. W. Gong, X. Zhu, S. Liu, M. Teng, and L. Niu Crystal structures of acutolysin A, a three-disulfide hemorrhagic zinc metalloproteinase from the snake venom of Agkistrodon acutus J. Mol. Biol. 283 1998 657 668
7. Q. Liu, W. Xu, W. Cheng, G. Jin, X. Shen, H. Lou, and J. Liu Molecular cloning and sequence analysis of cDNA encoding haemorrhagic toxin acutolysin A from Agkistrodon acutus Toxicon 37 1999 1539 1548
8. W.B. Wu, H.C. Peng, and T.F. Huang Crotalin a vWF and GPIb cleaving metalloproteinase from venom of Crotalus atrox Thromb. Haemostasis 86 2001 1501 1511
9. E.A. Hahn-Dantona, R.T. Aimes, and J.P. Quigley The isolation, characterization, and molecular cloning of a 75-kDa gelatinase B-like enzyme, a member of the matrix metalloproteinase (MMP) family. An avian enzyme that is MMP-9-like in its cell expression pattern but diverges from mammalian gelatinase B in sequence and biochemical properties J. Biol. Chem. 275 2000 40827 40838
10. J.F. Mustard, D.W. Perry, N.G. Ardlie, and M.A. Packham Preparation of suspension of washed platelet from humans Br. J. Haematol. 22 1972 193 204
11. W.J. Wang, and T.F. Huang Purification and characterization of a novel metalloproteinase, acurhagin, from Agkistrodon acutus venom Thromb. Haemostasis 87 2002 641 650
12. J. Nawarak, S. Phutrakul, and S.T. Chen Analysis of lectin-bound glycoproteins in snake venom from the Elapidae and Viperidae families J. Proteome Res. 3 2004 383 392
13. A.S. Kamiguti, C.R.M. Hay, R.D.G. Theakston, and M. Zuzel Insights into the mechanism of haemorrhage caused by snake venom metalloproteinases Toxicon 34 1996 627 642
14. F.S. Markland Jr. Snake venom fibrinogenolytic and fibrinolytic enzymes: an updated inventory Thromb. Haemostasis 79 1998 668 674
15. B.E. Fischer, U. Schlokat, M. Himmelspach, and F. Dorner Binding of hirudin to meizothrombin Protein Eng. 11 1998 715 721
16. M.C. Berndt, C.M. Ward, W.J. Booth, P.A. Castaldi, A.V. Mazurov, and R.K. Andrews Identification of aspartic acid 514 through glutamic acid 542 as a glycoprotein Ib-IX complex receptor recognition sequence in von Willebrand factor. Mechanism of modulation of von Willebrand factor by ristocetin and botrocetin Biochemistry 31 1992 11144 11151
17. D. Collen, and H.R. Lijnen Basic and clinical aspects of fibrinolysis and thrombolysis Blood 78 1991 3114 3124
18. F.S. Markland Snake venoms and the hemostatic system Toxicon 36 1998 1749 1800
19. T.W. Willis, and A.T. Tu Purification and biochemical characterization of atroxase, a nonhemorrhagic fibrinolytic protease from western diamondback rattlesnake venom Biochemistry 27 1988 4769 4777
20. J.B. Bjarnason, and J.W. Fox Hemorrhagic metalloproteinases from snake venoms Pharmacol. Ther. 62 1994 325 372
21. X. Xu, C. Wang, J. Liu, and Z. Lu Purification and characterization of hemorrhagic components from Agkistrodon acutus (hundred pace snake) venom Toxicon 19 1981 633 644
22. C. Ouyang, and T.F. Huang Purification and characterization of the fibrinolytic principle of Agkistrodon acutus venom Biochim. Biophys. Acta 439 1976 146 153
23. C. Ouyang, and T.F. Huang The properties of the purified fibrinolytic principle from Agkistrodon acutus snake venom Toxicon 15 1977 161 167
24. R.M. Kini, and H.J. Evans Structural domains in venom proteins: evidence that metalloproteinases and nonenzymatic platelet aggregation inhibitors (disintegrins) from snake venoms are derived by proteolysis from a common precursor Toxicon 30 1992 265 293
25. M.B. Silva, M. Schattner, C.R.R. Ramos, I.L.M. Junqueira-de-Azevedo, M.C. Guarnieri, M.A. Lazzari, C.A.M. Sampaio, R.G. Pozner, J.S. Ventura, P.L. Ho, and A.M. Chudzinski-Tavassi A prothrombin activator from Bothrops erythromelas (jararaca-da-seca) snake venom: characterization and molecular cloning Biochem. J. 369 2003 129 139