Effectiveness of batimastat, a synthetic inhibitor of matrix metalloproteinases, in neutralizing local tissue damage induced by BaP1, a hemorrhagic metalloproteinase from the venom of the snake Bothrops asper

Biochemical Pharmacology

Volumn 60, Issue 2, 2000, Pages 269-274

  Escalante, Teresa ^a   Franceschi, Aida ^a   Rucavado, Alexandra ^a   Gutiérrez, José María ^a  

^a UNIVERSIDAD DE COSTA RICA   (Costa Rica)

Author keywords

Batimastat; Bothrops asper; Hemorrhage; Hydroxamates; Matrix metalloproteinases; Metalloproteinase inhibitors; Snake venom; Venom metalloproteinases

Indexed keywords

BATIMASTAT; CASEIN; HYDROXAMIC ACID DERIVATIVE; MATRIX METALLOPROTEINASE INHIBITOR; METALLOPROTEINASE; SNAKE VENOM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOTINYLATION; BLEEDING; CONTROLLED STUDY; DRUG EFFICACY; EDEMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; SKIN NECROSIS; TISSUE INJURY;

ANIMALS; BOTHROPS; CARBON-OXYGEN LYASES; CROTALID VENOMS; DEOXYRIBONUCLEASE IV (PHAGE T4-INDUCED); DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; DRUG INTERACTIONS; EDEMA; HEMORRHAGE; MATRIX METALLOPROTEINASES; METALLOENDOPEPTIDASES; MICE; PHENYLALANINE; PROTEASE INHIBITORS; THIOPHENES;

EID: 0034662380     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(00)00302-6     Document Type: Article

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