Synthesis of triazole-linked β-C-glycosyl dimers as inhibitors of PTP1B

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 22, 2008, Pages 9757-9763

  Lin, Li ^a,b   Shen, Qiang ^c   Chen, Guo Rong ^b   Xie, Juan ^a  

^a UNIVERSITÉ PARIS SACLAY   (France)

^b EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

1,4 Benzoquinone; 1,4 Naphthoquinone; Aryl C glycosyl compounds; Click chemistry; Diabetes; Protein tyrosine phosphatase 1B

Indexed keywords

1,4 BENZOQUINONE DERIVATIVE; 1,4 DIMETHOXYBENZENE DERIVATIVE; 1,4 NAPHTHOQUINONE DERIVATIVE; DIMER; PROTEIN TYROSINE PHOSPHATASE 1B; PROTEIN TYROSINE PHOSPHATASE 1B INHIBITOR; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ACETYLATION; ARTICLE; DRUG SYNTHESIS; ENZYME INHIBITOR INTERACTION; IC 50; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION;

BENZOQUINONES; DIABETES MELLITUS, TYPE 2; DIMERIZATION; ENZYME INHIBITORS; GLYCOSIDES; HYPOGLYCEMIC AGENTS; INHIBITORY CONCENTRATION 50; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1;

EID: 54949158918     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.09.066     Document Type: Article

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