Synthesis of benzofuran scaffold-based potential PTP-1B inhibitors

Bioorganic and Medicinal Chemistry

Volumn 15, Issue 2, 2007, Pages 727-734

  Dixit, Manish ^a   Tripathi, Brajendra K ^a   Tamrakar, Akhilesh K ^a   Srivastava, Arvind K ^a   Kumar, Brijesh ^a   Goel, Atul ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Benzofuran and furanoflavonoid; Diabetes; Insulin resistance; Protein tyrosine phosphatase 1B

Indexed keywords

1 (4 ACETYL 5,5' DIHYDROXY 2',3' DIHYDRO[2,3']DIBENZOFURANYL 40 YL)ETHANONE; 1 (5 ACETYL 4,4' DIHYDROXY 2',3' DIHYDRO[2,3']DIBENZOFURANYL 5' YL)ETHANONE; 1 (5 ACETYL 6,6' DIHYDROXY 2',3' DIHYDRO[2,3']DIBENZOFURANYL 5' YL)ETHANONE; 1 (5 ACETYL 6,6' DIMETHOXY 2',3' DIHYDRO[2,3']DIBENZOFURANYL 50 YL)ETHANONE; 1 (6' ACETYL 5,5' DIHYDROXY 2',3' DIHYDRO[2,3']DIBENZOFURANYL 6 YL)ETHANONE; 1 (7' ACETYL 6,6' DIHYDROXY 2',3' DIHYDRO[2,3']DIBENZOFURANYL 7 YL)ETHANONE; 2 (4 METHOXYPHENYL)FURO[2,3 H]CHROMEN 4 ONE; 2 PHENYLFURO[2,3 H]CHROMEN 4 ONE; 3 (2 CHLOROPHENYL) 3 HYDROXY 1 (4 METHOXYBENZOFURAN 5 YL)PROPENONE; 3 (3,4 DIMETHOXYPHENYL) 3 HYDROXY 1 (6 HYDROXYBENZOFURAN 5 YL)PROPENONE; 3 BENZO[1,3]DIOXOL 5 YL 3 HYDROXY 1 (4 METHOXYBENZOFURAN 5 YL)PROPENONE; 3 BENZO[1,3]DIOXOL 5 YL 3 HYDROXY 1 (6 HYDROXYBENZOFURAN 5 YL)PROPENONE; 3 HYDROXY 1 (4 HYDROXYBENZOFURAN 5 YL) 3 PHENYLPROPENONE; 3 HYDROXY 1 (4 METHOXYBENZOFURAN 5 YL) 3 (4 METHOXYPHENYL)PROPENONE; 3 HYDROXY 1 (6 HYDROXYBENZOFURAN 5 YL) 3 (3 METHOXYPHENYL)PROPENONE; 3 HYDROXY 1 (6 HYDROXYBENZOFURAN 5 YL) 3 (4 METHOXYPHENYL)PROPENONE; 3 HYDROXY 1 (6 HYDROXYBENZOFURAN 5 YL) 3 PHENYLPROPENONE; 3 HYDROXY 1 (6 METHOXYBENZOFURAN 5 YL) 3 PHENYLPROPENONE; 4,4' DIHYDROXY 2',3' DIHYDRO[2,3']DIBENZOFURANYL 5,5' DICARBOXYLIC ACID DIMETHYL ESTER; 7 (3 METHOXYPHENYL)FURO[3,2 G]CHROMEN 5 ONE; 7 (3,4 DIMETHOXYPHENYL)FURO[3,2 G]CHROMEN 5 ONE; 7 (4 METHOXYPHENYL)FURO[3,2 G]CHROMEN 5 ONE; 7 BENZO[1,3]DIOXOL 5 YLFURO[3,2 G]CHROMEN 5 ONE; 7 PHENYLFURO[3,2 G]CHROMEN 5 ONE; BENZOFURAN DERIVATIVE; PROTEIN TYROSINE PHOSPHATASE 1B INHIBITOR;

ARTICLE; CATALYSIS; CYCLIZATION; DRUG ACTIVITY; DRUG INHIBITION; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; STRUCTURE ACTIVITY RELATION;

BENZOFURANS; CHROMATOGRAPHY, THIN LAYER; CYCLIZATION; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; INDICATORS AND REAGENTS; MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN-TYROSINE-PHOSPHATASE; SPECTROMETRY, MASS, FAST ATOM BOMBARDMENT; VANADATES;

EID: 33845291522     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2006.10.053     Document Type: Article

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