Evidences for age-related modulation of human hematopoietic progenitor cell proliferation

Experimental Gerontology

Volumn 43, Issue 11, 2008, Pages 1033-1038

  Santos, Alexander Navarrete ^a   Kahrstedt, Simone ^a   Nass, Norbert ^a   Czeslick, Elke ^a   Scheubel, Robert J ^a   Silber, Rolf Edgar ^a   Simm, Andreas ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

Galactosidase activity; Ageing; Hematopoietic stem cells; Oxi blot; Senescence

Indexed keywords

BETA GALACTOSIDASE; BIOLOGICAL MARKER; CHEMOKINE;

ADULT; AGED; ARTICLE; BLOOD SAMPLING; CARBONYLATION; CELL AGING; CELL DENSITY; CELL EXPANSION; CELL PROLIFERATION; GROUPS BY AGE; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; NORMAL HUMAN; PRIORITY JOURNAL; SENESCENCE;

ADULT; AGED; AGING; ANTIGENS, CD; ANTIGENS, CD34; BETA-GALACTOSIDASE; BIOLOGICAL MARKERS; CELL AGING; CELL PROLIFERATION; CHEMOKINES; FEMALE; FLOW CYTOMETRY; GLYCOPROTEINS; HEMATOPOIETIC STEM CELLS; HUMANS; MALE; MIDDLE AGED; PEPTIDES; PROTEIN CARBONYLATION; YOUNG ADULT;

EID: 54949087476     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exger.2008.08.042     Document Type: Article

References (42)

1. Aguilaniu H., Gustafsson L., Rigoulet M., and Nyström T. Asymmetric inheritance of oxidatively damaged proteins during cytokinesis. Science 299 (2003) 1751-1753
2. Chambers S.M., and Goodell M.A. Hematopoietic stem cell ageing: wrinkles in stem cell potential. Stem Cell Rev. 3 (2007) 201-211
3. Chambers S.M., Shaw C.A., Gatza C., Fisk C.J., Donehower L.A., and Goodell M.A. Ageing hematopoietic stem cells decline in function and exhibit epigenetic dysregulation. PLoS Biol. 5 (2007) e201
4. Constantin A., Constantinescu E., Dumitrescu M., Calin A., and Popov D. Effects of ageing on carbonyl stress and antioxidant defense in RBCs of obese type 2 diabetic patients. J. Cell. Mol. Med. 9 (2005) 683-691
5. Conboy I.M., Conboy M.J., Wagers A.J., Girma E.R., Weissman I.L., and Rando T.A. Rejuvenation of aged progenitor cells by exposure to a young systemic environment. Nature 433 (2005) 760-764
6. Dalle-Donne I., Giustarini D., Colombo R., Rossi R., and Milzani A. Protein carbonylation in human diseases. Trends Mol. Med. 9 (2003) 169-176
7. De Haan G., and Gerrits A. Epigenetic control of hematopoietic stem cell ageing the case of Ezh2. Ann. NY Acad. Sci. 1106 (2007) 233-329
8. Dimri G.P., Lee X., Basile G., Acosta M., Scott G., Roskelley C., Medrano E.E., Linskens M., Rubelj I., Pereira-Smith O., Peacoke M., and Campisi J. A biomarker that identifies senescent human cells in culture and in ageing skin in vivo. Proc. Natl. Acad. Sci. USA 92 (1995) 9363-9367
9. Furuichi K., Wada T., Kitajikma S., Toyama T., Okumura T., Hara A., Kawachi H., Shimizu F., Sugaya T., Mukaida N., Narumi S., Matsushima K., and Kaneko S. IFN-inducible protein 10 (CXCL10) regulates tubular cell proliferation in renal ischemia-reperfusion injury. Nephron Exp. Nephrol. 109 (2008) c29-c38
10. Geiger H., Rennebeck G., and Van Zant G. Regulation of hematopoietic stem cell ageing in vivo by a distinct genetic element. Proc. Natl. Acad. Sci. USA 102 (2005) 5102-5107
11. Geiger H., and Van Zant G. The ageing of lympho-hematopoietic stem cells. Nat. Immunol. 3 (2002) 329-333
12. Hernebring M., Brolén G., Aguilaniu H., Semb H., and Nyström T. Elimination of damaged proteins during differentiation of embryonic stem cells. Proc. Natl. Acad. Sci. USA 103 (2006) 7700-7705
13. Kayali R., Cakatay U., Uzun H., and Genç H. Gender difference as regards myocardial protein oxidation in aged rats: male rats have increased oxidative protein damage. Biogerontology 8 (2007) 653-661
14. Levine R.L. Carbonyl modified proteins in cellular regulation, ageing, and disease. Free Radic. Biol. Med. 32 (2002) 790-796
15. Li C.L., and Johnson G.R. Rhodamine123 reveals heterogeneity within murine Lin_, Sca-1_ hemopoietic stem cells. J. Exp. Med. 175 (1992) 1443-1447
16. Maier A.B., Westendorp R.G., and Van Heemst D. Beta-galactosidase activity as a biomarker of replicative senescence during the course of human fibroblast cultures. Ann. NY Acad. Sci. 1100 (2007) 323-332
17. Metcalf D., and Nicola N.A. The clonal proliferation of normal mouse hematopoietic cells: enhancement and suppression by colony-stimulating factor combinations. Blood 79 (1992) 2861-2866
18. Metcalf D. Stem cells, pre-progenitor cells and lineage-committed cells: are our dogmas correct?. Ann. NY Acad. Sci. 872 (1999) 289-303
19. Metcalf D., Di Rago L., and Mifsud S. Synergistic and inhibitory interactions in the in vitro control of murine megakaryocyte colony formation. Stem Cells 20 (2002) 552-560
20. Metcalf D. Hematopoietic cytokines. Blood 111 (2008) 485-491
21. Meunch M.D., Schneider J.G., and Moore M.A.S. Interaction amongst colony stimulating factors, IL-1b, IL-6 and kit-ligand in the regulation of primitive murine hematopoietic cells. Exp. Hematol. 20 (1992) 339-349
22. Migliaccio G., Migliaccio A.R., Valinsky J., Langley K., Zsebo K., Visser J.W., and Adamson J.W. Stem cell factor induces proliferation and differentiation of highly enriched murine hematopoietic cells. Proc. Natl. Acad. Sci. USA 88 (1991) 7420-7424
23. Mo R., Chen J., Han Y., Bueno-Cannizares C., Mise D.E., Lescure P.A., Hanash S., and Yung R.L. T cell chemokine receptor expression in aging. J. Immunol. 170 (2003) 895-904
24. Nijnik A., Woodbine L., Marchetti C., Dawson S., Lambe T., Liu C., Rodrigues N.P., Crockford T.L., Cabuy E., Vindigni A., Enver T., Bell J.I., Slijepcevic P., Goodnow C.C., Jeggo P.A., and Cornall R.J. DNA repair is limiting for haematopoietic stem cells during ageing. Nature 447 (2007) 686-690
25. Nyström T. Role of oxidative carbonylation in protein quality control and senescence. EMBO J. 24 (2005) 1311-1317
26. Oliver C.N., Ahn B.W., Moerman E.J., Goldstein S., and Stadtman E.R. Age-related changes in oxidized proteins. J. Biol. Chem. 262 (1987) 5488-5491
27. Poggioli S., Bakala H., and Friguet B. Age-related increase of protein glycation in peripheral blood lymphocytes is restricted to preferential target proteins. Exp. Gerontol. 37 (2002) 1207-1215
28. Puxeddu I., Bader R., Piliponsky A.M., Reich R., Levi-Schaffer F., and Berkman N. The CC chemokine eotaxin/CCL11 has a selective profibrogenic effect on human lung fibroblasts. J. Allergy Clin. Immunol. 117 (2006) 103-110
29. Rossi D.J., Bryder D., Seita J., Nussenzweig A., Hoeijmakers J., and Weissman I.L. Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age. Nature 447 (2007) 725-729
30. Rossi D.J., Seita J., Czechowicz A., Bhattacharya D., Bryder D., and Weissman I.L. Hematopoietic stem cell quiescence attenuates DNA damage response and permits DNA damage accumulation during ageing. Cell Cycle 6 (2007) 2371-2376
31. Scheubel R.J., Kahrstedt S., Weber H., Holtz J., Friedrich I., Borgermann J., Silber R.-E., and Simm A. Depression of progenitor cell function by advanced glycation endproducts (AGEs): potential relevance for impaired angiogenesis in advanced age and diabetes. Exp. Gerontol. 41 (2006) 540-548
32. Scheubel R.J., Zorn H., Silber R.E., Kuss O., Morawietz H., Holtz J., and Simm A. Age-dependent depression in circulating endothelial progenitor cells in patients undergoing coronary artery bypass grafting. J. Am. Coll. Cardiol. 42 (2003) 2073-2080
33. Shurin G.V., Yurkovetsky Z.R., Chatta G.S., Tourkova I.L., Shurin M.R., and Lokshin A.E. Dynamic alteration of soluble serum biomarkers in healthy ageing. Cytokine 39 (2007) 123-129
34. Stadtman E.R. Protein oxidation and ageing. Science 257 (1992) 1220-1224
35. Stadtman E.R. Protein oxidation in ageing and age-related diseases. Ann. NY Acad. Sci. 928 (2001) 22-38
36. Stolzing A., Sethe S., and Scutti A.M. Stressed stem cells: temperature response in aged mesenchymal stem cells. Stem Cells 15 (2006) 478-487
37. Thum T., Hoeber S., Froese S., Klink I., Stichtenoth D.O., Galuppo P., Jakob M., Tsikas D., Anker S.D., Poole-Wilson P.A., Borlak J., Ertl G., and Bauersachs J. Age-dependent impairment of endothelial progenitor cells is corrected by growth-hormone-mediated increase of insulin-like growth-factor-1. Circ. Res. 100 (2007) 434-443
38. Viedt C., Vogel J., Athanasiou T., Shen W., Orth S.R., Kübler W., and Kreuzer J. Monocyte chemoattractant protein-1 induces proliferation and interleukin-6 production in human smooth muscle cells by differential activation of nuclear factor-kappaB and activator protein-1. Arterioscler. Thromb. Vasc. Biol. 22 (2002) 914-920
39. Wörnle M., Schmid H., Merkle M., and Banas B. Effects of chemokines on proliferation and apoptosis of human mesangial cells. BMC Nephrol. 5 (2004) 8
40. Yan L.J., Levine R.L., and Sohal R.S. Oxidative damage during ageing targets mitochondrial aconitase. Proc. Natl. Acad. Sci. USA 94 (1997) 11168-11172
41. Yan L.J., and Sohal R.S. Mitochondrial adenine nucleotide translocase is modified oxidatively during ageing. Proc. Natl. Acad. Sci. USA 95 (1998) 12896-12901
42. Zhou S., Greenberger J.S., Epperly M.W., Goff J.P., Adler C., Leboff M.S., and Glowacki J. Age-related intrinsic changes in human bone-marrow-derived mesenchymal stem cells and their differentiation to osteoblasts. Aging Cell 7 (2008) 335-343