Age-related increase of protein glycation in peripheral blood lymphocytes is restricted to preferential target proteins

Experimental Gerontology

Volumn 37, Issue 10-11, 2002, Pages 1207-1215

  Poggioli, Sylvie ^a   Bakala, Hilaire ^a   Friguet, Bertrand ^a  

^a UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

Advanced glycation end products; Aging; Aging biomarkers; Human lymphocytes; Protein glycation; Proteomics

Indexed keywords

BIOLOGICAL MARKER; GLYCOSYLATED PROTEIN; PROTEIN ANTIBODY; RIBONUCLEASE; ADVANCED GLYCATION END PRODUCT; PROTEIN;

ADULT; AGE; AGED; AGING; CELL FUNCTION; CELL LYSATE; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GEL ELECTROPHORESIS; HUMAN; IMMUNOBLOTTING; IMMUNOREACTIVITY; LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN GLYCOSYLATION; PROTEIN TARGETING; SILVER STAINING; WESTERN BLOTTING; ARTICLE; CELL AGING; CYTOLOGY; GLYCOSYLATION; METABOLISM; METHODOLOGY; PHYSIOLOGY; TWO DIMENSIONAL GEL ELECTROPHORESIS;

ADULT; AGED; AGED, 80 AND OVER; BLOTTING, WESTERN; CELL AGING; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; GLYCOSYLATION; GLYCOSYLATION END PRODUCTS, ADVANCED; HUMANS; LYMPHOCYTES; PROTEINS;

EID: 0036815516     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0531-5565(02)00145-6     Document Type: Conference Paper

References (40)

1. Aspinall R., Andrew D. Immunosenescence: potential causes and strategies for reversal. Biochem. Soc. Trans. 28:2000;250-254.
2. Aulak K.S., Miyagi M., Yan L., West K.A., Massillon D., Crabb J.W., Stuehr D.J. Proteomic method identifies proteins nitrated in vivo during inflammatory challenge. Proc. Natl. Acad. Sci. USA. 98:2001;12056-12061.
3. Bank R.A., Bayliss M.T., Lafeber F.P., Maroudas A., Tekoppele J.M. Ageing and zonal variation in post-translational modification of collagen in normal human articular cartilage. The age-related increase in non-enzymatic glycation affects biomechanical properties of cartilage. Biochem. J. 330:1998;345-351.
4. Beckman K.B., Ames B.N. The free radical theory of aging matures. Physiol. Rev. 78:1998;547-581.
5. Beregi E., Regius O., Rajczy K. Comparative study of the morphological changes in lymphocytes of elderly individuals and centenarians. Age Ageing. 20:1991;55-59.
6. Berlett B.S., Stadtman E.R. Protein oxidation in aging, disease, and oxidative stress. J. Biol. Chem. 272:1997;20313-20316.
7. Bulteau A., Petropoulos I., Friguet B. Age-related alterations of proteasome structure and function in aging epidermis. Exp. Gerontol. 35:2000;767-777.
8. Bulteau A.L., Lundberg K.C., Humphries K.M., Sadek H.A., Szweda P.A., Friguet B., Szweda L.I. Oxidative modification and inactivation of the proteasome during coronary occlusion/reperfusion. J. Biol. Chem. 276:2001;30057-30063.
9. Bulteau A.L., Verbeke P., Petropoulos I., Chaffotte A.F., Friguet B. Proteasome inhibition in glyoxal-treated fibroblasts and resistance of glycated glucose-6-phosphate dehydrogenase to 20 S proteasome degradation in vitro. J. Biol. Chem. 276:2001;45662-45668.
10. Conconi M., Szweda L.I., Levine R.L., Stadtman E.R., Friguet B. Age-related decline of rat liver multicatalytic proteinase activity and protection from oxidative inactivation by heat-shock protein 90. Arch. Biochem. Biophys. 331:1996;232-240.
11. Dunn J.A., Patrick J.S., Thorpe S.R., Baynes J.W. Oxidation of glycated proteins: age-dependent accumulation of Nepsilon-(carboxymethyl)lysine in lens proteins. Biochemistry. 28:1989;9464-9468.
12. Fratelli M., Demol H., Puype M., Casagrande S., Eberini I., Salmona M., Bonetto V., Mengozzi M., Duffieux F., Miclet E., Bachi A., Vandekerckhove J., Gianazza E., Ghezzi P. Identification by redox proteomics of glutathionylated proteins in oxidatively stressed human T lymphocytes. Proc. Natl. Acad. Sci. USA. 99:2002;3505-3510.
13. Friguet B. Aging of proteins and the proteasome. Prog. Mol. Subcell. Biol. 29:2002;17-33.
14. Friguet B., Bulteau A.L., Chondrogianni N., Conconi M., Petropoulos I. Protein degradation by the proteasome and its implications in aging. Ann. NY Acad. Sci. 908:2000;143-154.
15. Globerson A., Effros R.B. Ageing of lymphocytes and lymphocytes in the aged. Immunol. Today. 21:2000;515-521.
16. Horie K., Miyata T., Yasuda T., Takeda A., Yasuda Y., Maeda K., Sobue G., Kurokawa K. Immunohistochemical localization of advanced glycation end products, pentosidine, and carboxymethyllysine in lipofuscin pigments of Alzheimer's disease and aged neurons. Biochem. Biophys. Res. Commun. 236:1997;327-332.
17. Jana C.K., Das N., Sohal R.S. Specificity of age-related carbonylation of plasma proteins in the mouse and rat. Arch. Biochem. Biophys. 397:2002;433-439.
18. Kaufmann H., Bailey J.E., Fussenegger M. Use of antibodies for detection of phosphorylated proteins separated by two-dimensional gel electrophoresis. Proteomics. 1:2001;194-199.
19. Keller T.N., Huang F.F., Zhu T., Yu T., Ho Y.S., Kindy T.S. Oxidative stress-associated impairment of proteasome activity during ischemia-reperfusion injury. J. Cereb. Blood Flow Metab. 20:2000;1467-1473.
20. Kimura T., Takamatsu J., Miyata T., Miyakawa T., Horiuchi S. Localization of identified advanced glycation end-product structures. Nepsilon(carboxymethyl)lysine and pentosidine, in age-related inclusions in human brains. Pathol. Int. 48:1998;575-579.
21. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:1970;680-685.
22. Ling X., Sakashita N., Takeya M., Nagai R., Horiuchi S., Takahashi K. Immunohistochemical distribution and subcellular localization of three distinct specific molecular structures of advanced glycation end products in human tissues. Lab. Invest. 78:1998;1591-1606.
23. Linton P., Thoman M.L. T cell senescence. Front Biosci. 6:2001;D248-D261.
24. Merril C.R., Goldman D., Sedman S., Ebert H. Ultrasensitive stain for proteins in polyacrylamide gels show regional variation in cerebrospinal fluid proteins. Science. 211:1981;1437-1438.
25. Miyata T., van Ypersele de Strihou C., Kurokawa K., Baynes J.W. Alterations in nonenzymatic biochemistry in uremia: origin and significance of carbonyl stress in long-term uremic complications. Kidney Int. 55:1999;389-399.
26. Okada K., Wangpoengtrakul C., Osawa T., Toyokuni S., Tanaka K., Uchida K. 4-Hydroxy-2-nonenal-mediated impairment of intracellular proteolysis during oxidative stress. Identification of proteasomes as target molecules. J. Biol. Chem. 274:1999;23787-23793.
27. Pawelec G., Barnett Y., Forsey R., Frasca D., Globerson A., McLeod J., Caruso C., Franceschi C., Fulop T., Gupta S., Mariani E., Mocchegiani E., Solana R. T cells and aging, January 2002 update. Front Biosci. 7:2002;D1056-D1183.
28. Petropoulos I., Conconi M., Wang X., Hoenel B., Bregegere F., Milner Y., Friguet B. Increase of oxidatively modified protein is associated with a decrease of proteasome activity and content in aging epidermal cells. J. Gerontol. A Biol. Sci. Med. Sci. 55:2000;B220-B227.
29. Ponnappan U. Ubiquitin-proteasome pathway is compromised in CD45RO+ and CD45RA+ T lymphocyte subsets during aging. Exp. Gerontol. 37:2002;359-367.
30. Ponnappan U., Zhong M., Trebilcock G.U. Decreased proteasome-mediated degradation in T cells from the elderly: a role in immune senescence. Cell Immunol. 192:1999;167-174.
31. Sell D.R., Monnier V.M. Structure elucidation of a senescence cross-link from human extracellular matrix. Implication of pentoses in the aging process. J. Biol. Chem. 264:1989;21597-21602.
32. Sell D.R., Primc M., Schafer I.A., Kovach M., Weiss M.A., Monnier V.M. Cell-associated pentosidine as a marker of aging in human diploid cells in vitro and in vivo. Mech. Ageing Dev. 105:1998;221-240.
33. Stadtman E.R., Levine R.L. Protein oxidation. Ann. NY Acad. Sci. 899:2000;191-208.
34. Talent J.M., Kong Y., Gracy R.W. A double stain for total and oxidized proteins from two-dimensional fingerprints. Anal. Biochem. 263:1998;31-38.
35. Teillet L., Verbeke P., Gouraud S., Bakala H., Borot-Laloi C., Heudes D., Bruneval P., Corman B. Food restriction prevents advanced glycation end product accumulation and retards kidney aging in lean rats. J. Am. Soc. Nephrol. 11:2000;1488-1497.
36. Verbeke P., Perichon M., Borot-Laloi C., Schaeverbeke J., Bakala H. Accumulation of advanced glycation end products in the rat nephron: link with circulating AGEs during aging. J. Histochem. Cytochem. 45:1997;1059-1068.
37. Verbeke P., Clark B.F., Rattan S.I. Modulating cellular aging in vitro: hormetic effects of repeated mild heat stress on protein oxidation and glycation. Exp. Gerontol. 35:2000;787-794.
38. Verzijl N., DeGroot J., Oldehinkel E., Bank R.A., Thorpe S.R., Baynes J.W., Bayliss M.T., Bijlsma J.W., Lafeber F.P., Tekoppele J.M. Age-related accumulation of Maillard reaction products in human articular cartilage collagen. Biochem. J. 350 Pt 2:2000;381-387.
39. Yan L.J., Sohal R.S. Mitochondrial adenine nucleotide translocase is modified oxidatively during aging. Proc. Natl. Acad. Sci. USA. 95:1998;12896-12901.
40. Yan L.J., Levine R.L., Sohal R.S. Oxidative damage during aging targets mitochondrial aconitase. Proc. Natl. Acad. Sci. USA. 94:1997;11168-11172.