-
1
-
-
33749321945
-
-
An D, Rodrigues B. Role of changes in cardiac metabolism in development of diabetic cardiomyopathy. Am J Physiol Heart Circ Physiol 2006; 291: H1489-H15O6
-
An D, Rodrigues B. Role of changes in cardiac metabolism in development of diabetic cardiomyopathy. Am J Physiol Heart Circ Physiol 2006; 291: H1489-H15O6
-
-
-
-
2
-
-
0037119410
-
Leptin activates cardiac fatty acid oxidation independent of changes in the AMP-activated protein kinase-acetyl-CoA carboxylase-malonyl-CoA axis
-
Atkinson LL, Fischer MA, Lopaschuk GD. Leptin activates cardiac fatty acid oxidation independent of changes in the AMP-activated protein kinase-acetyl-CoA carboxylase-malonyl-CoA axis. J Biol Chem 2002; 277: 29424-29430
-
(2002)
J Biol Chem
, vol.277
, pp. 29424-29430
-
-
Atkinson, L.L.1
Fischer, M.A.2
Lopaschuk, G.D.3
-
3
-
-
0043025552
-
Heart failure: The frequent, forgotten, and often fatal complication of diabetes
-
Bell DS. Heart failure: the frequent, forgotten, and often fatal complication of diabetes. Diabetes Care 2003; 26: 2433-2441
-
(2003)
Diabetes Care
, vol.26
, pp. 2433-2441
-
-
DS, B.1
-
4
-
-
0034603545
-
Stress hyperglycaemia and increased risk of death after myocardial infarction in patients with and without diabetes: A systematic overview
-
Capes SE, Hunt D, Malmberg K, Gerstein HC. Stress hyperglycaemia and increased risk of death after myocardial infarction in patients with and without diabetes: a systematic overview. Lancet 2000; 355: 773-778
-
(2000)
Lancet
, vol.355
, pp. 773-778
-
-
Capes, S.E.1
Hunt, D.2
Malmberg, K.3
Gerstein, H.C.4
-
6
-
-
13444268937
-
Transgenic expression of fatty acid transport protein 1 in the heart causes lipotoxic cardiomyopathy
-
Chiu HC, Kovacs A, Blanton RM, Han X, Courtois M, Weinheimer CJ, Yamada KA, Brunet S, Xu H, Nerbonne JM, Welch MJ, Fettig MW, Sharp TL, Sambandam N, Olson MW, Ory DS, Schaffer JE. Transgenic expression of fatty acid transport protein 1 in the heart causes lipotoxic cardiomyopathy. Circ Res 2005; 96: 225-233
-
(2005)
Circ Res
, vol.96
, pp. 225-233
-
-
Chiu, H.C.1
Kovacs, A.2
Blanton, R.M.3
Han, X.4
Courtois, M.5
Weinheimer, C.J.6
Yamada, K.A.7
Brunet, S.8
Xu, H.9
Nerbonne, J.M.10
Welch, M.J.11
Fettig, M.W.12
Sharp, T.L.13
Sambandam, N.14
Olson, M.W.15
Ory, D.S.16
Schaffer, J.E.17
-
7
-
-
0035061419
-
A novel mouse model of lipotoxic cardiomyopathy
-
Chiu HC, Kovacs A, Ford DA, Hsu FF, Garcia R, Herrero P, Saffitz JE, Schaffer JE. A novel mouse model of lipotoxic cardiomyopathy. J Clin Invest 2001; 107: 813-822
-
(2001)
J Clin Invest
, vol.107
, pp. 813-822
-
-
Chiu, H.C.1
Kovacs, A.2
Ford, D.A.3
Hsu, F.F.4
Garcia, R.5
Herrero, P.6
Saffitz, J.E.7
Schaffer, J.E.8
-
8
-
-
0033611663
-
The Croonian Lecture 1998. Identification of a protein kinase cascade of major importance in insulin signal transduction
-
Cohen P. The Croonian Lecture 1998. Identification of a protein kinase cascade of major importance in insulin signal transduction. Philos Trans R Soc Lond B Biol Sci 1999; 354: 485-495
-
(1999)
Philos Trans R Soc Lond B Biol Sci
, vol.354
, pp. 485-495
-
-
Cohen, P.1
-
9
-
-
0026000171
-
Detection of low phosphocreatine to ATP ratio in failing hypertrophied human myocardium by 31P magnetic resonance spectroscopy
-
Conway MA, Allis J, Ouwerkerk R, Niioka T, Rajagopalan B, Radda GK. Detection of low phosphocreatine to ATP ratio in failing hypertrophied human myocardium by 31P magnetic resonance spectroscopy. Lancet 1991; 338: 973-976
-
(1991)
Lancet
, vol.338
, pp. 973-976
-
-
Conway, M.A.1
Allis, J.2
Ouwerkerk, R.3
Niioka, T.4
Rajagopalan, B.5
Radda, G.K.6
-
10
-
-
3042739406
-
Vusse GJ van der, Bonen A, Glatz JF, Luiken JJ. Enhanced sarcolemmal FAT/CD36 content and triacylglycerol storage in cardiac myocytes from obese zucker rats
-
Coort SL, Hasselbaink DM, Koonen DP, Willems J, Coumans WA, Chabowski A, Vusse GJ van der, Bonen A, Glatz JF, Luiken JJ. Enhanced sarcolemmal FAT/CD36 content and triacylglycerol storage in cardiac myocytes from obese zucker rats. Diabetes 2004; 53: 1655-1663
-
(2004)
Diabetes
, vol.53
, pp. 1655-1663
-
-
Coort, S.L.1
Hasselbaink, D.M.2
Koonen, D.P.3
Willems, J.4
Coumans, W.A.5
Chabowski, A.6
-
11
-
-
0029587224
-
Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
-
Cross DA, Alessi DR, Cohen P, Andjelkovich M, Hemmings BA. Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 1995; 378: 785-789
-
(1995)
Nature
, vol.378
, pp. 785-789
-
-
Cross, D.A.1
Alessi, D.R.2
Cohen, P.3
Andjelkovich, M.4
Hemmings, B.A.5
-
12
-
-
0037125371
-
Altered myocardial fatty acid and glucose metabolism in idiopathic dilated cardiomyopathy
-
Davila-Roman VG, Vedala G, Herrero P, de las Fuentes L, Rogers JG, Kelly DP, Gropler RJ. Altered myocardial fatty acid and glucose metabolism in idiopathic dilated cardiomyopathy. J Am Coll Cardioi 2002; 40: 271-277
-
(2002)
J Am Coll Cardioi
, vol.40
, pp. 271-277
-
-
Davila-Roman, V.G.1
Vedala, G.2
Herrero, P.3
de las Fuentes, L.4
Rogers, J.G.5
Kelly, D.P.6
Gropler, R.J.7
-
13
-
-
0037417725
-
A critical role for PPARalpha-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: Modulation by dietary fat content
-
Finck BN, Han Y, Courtois M, Aimond F, Nerbonne JM, Kovacs A, Gross RW, Kelly DP. A critical role for PPARalpha-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: modulation by dietary fat content. Proc Natl Acad Sci USA 2003; 100: 1226-1231
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 1226-1231
-
-
Finck, B.N.1
Han, Y.2
Courtois, M.3
Aimond, F.4
Nerbonne, J.M.5
Kovacs, A.6
Gross, R.W.7
Kelly, D.P.8
-
14
-
-
0036143320
-
The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus
-
Finck BN, Lehman JJ, Leone TC, Welch MJ, Bennett MJ, Kovacs A, Han X, Gross RW, Kozak R, Lopaschuk GD, Kelly DP. The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus. J Clin Invest 2002; 109: 121-130
-
(2002)
J Clin Invest
, vol.109
, pp. 121-130
-
-
Finck, B.N.1
Lehman, J.J.2
Leone, T.C.3
Welch, M.J.4
Bennett, M.J.5
Kovacs, A.6
Han, X.7
Gross, R.W.8
Kozak, R.9
Lopaschuk, G.D.10
Kelly, D.P.11
-
15
-
-
0033542414
-
-
Fulton D, Gratton JP, MacCabe TJ, Fontana J, Fujio Y, Walsh K, Franke TF, Papapetropoulos A, Sessa WC. Regulation of endothelium-derived nitric oxide production by the protein kinase Akt. Nature 1999; 399: 597-601
-
Fulton D, Gratton JP, MacCabe TJ, Fontana J, Fujio Y, Walsh K, Franke TF, Papapetropoulos A, Sessa WC. Regulation of endothelium-derived nitric oxide production by the protein kinase Akt. Nature 1999; 399: 597-601
-
-
-
-
16
-
-
6344292507
-
Diabetes mellitus and heart failure: Basic mechanisms, clinical features, and therapeutic considerations
-
Giles TD, Sander GE. Diabetes mellitus and heart failure: basic mechanisms, clinical features, and therapeutic considerations. Cardiol Clin 2004; 22: 553-568
-
(2004)
Cardiol Clin
, vol.22
, pp. 553-568
-
-
Giles, T.D.1
Sander, G.E.2
-
17
-
-
23044450269
-
Van, Adrogue JV, Brown KK, Taegtmeyer H. Activation of PPAR-gamma enhances myocardial glucose oxidation and improves contractile function in isolated working hearts of ZDF rats
-
Golfman LS, Wilson CR, Sharma S, Burgmaier M, Young ME, Guthrie PH, Arsdall M Van, Adrogue JV, Brown KK, Taegtmeyer H. Activation of PPAR-gamma enhances myocardial glucose oxidation and improves contractile function in isolated working hearts of ZDF rats. Am J Physiol Endocrinol Metab 2005; 289: E328-E336
-
(2005)
Am J Physiol Endocrinol Metab
, vol.289
-
-
Golfman, L.S.1
Wilson, C.R.2
Sharma, S.3
Burgmaier, M.4
Young, M.E.5
Guthrie, P.H.6
Arsdall, M.7
-
18
-
-
0027537622
-
Na(+)-dependent creatine transporter in rabbit brain, muscle, heart, and kidney. cDMA cloning and functional expression
-
Guimbal C, Kilimann MW. A Na(+)-dependent creatine transporter in rabbit brain, muscle, heart, and kidney. cDMA cloning and functional expression. J Biol Chem 1993; 268: 8418-8421
-
(1993)
J Biol Chem
, vol.268
, pp. 8418-8421
-
-
Guimbal, C.1
Kilimann MW, A.2
-
19
-
-
0025738240
-
Altered myocardial high-energy phosphate metabolites in patients with dilated cardiomyopathy
-
Hardy CJ, Weiss RG, Bottomley PA, Gerstenblith G. Altered myocardial high-energy phosphate metabolites in patients with dilated cardiomyopathy. Am Heart J 1991; 122: 795-801
-
(1991)
Am Heart J
, vol.122
, pp. 795-801
-
-
Hardy, C.J.1
Weiss, R.G.2
Bottomley, P.A.3
Gerstenblith, G.4
-
20
-
-
34147112332
-
Glucose levels predict hospitalization for congestive heart failure in patients at high cardiovascular risk
-
Held C, Gerstein HC, Yusuf S, Zhao F, Hilbrich L, Anderson C, Sleight P, Teo K. Glucose levels predict hospitalization for congestive heart failure in patients at high cardiovascular risk. Circulation 2007; 115: 1371-1375
-
(2007)
Circulation
, vol.115
, pp. 1371-1375
-
-
Held, C.1
Gerstein, H.C.2
Yusuf, S.3
Zhao, F.4
Hilbrich, L.5
Anderson, C.6
Sleight, P.7
Teo, K.8
-
21
-
-
22844432105
-
Pioglitazone improves left ventricular diastolic function in patients with essential hypertension
-
Horio T, Suzuki M, Suzuki K, Takamisawa I, Hiuge A, Kamide K, Takiuchi S, Iwashima Y, Kihara S, Funahashi T, Yoshimasa Y, Kawano Y. Pioglitazone improves left ventricular diastolic function in patients with essential hypertension. Am J Hypertens 2005; 18: 949-957
-
(2005)
Am J Hypertens
, vol.18
, pp. 949-957
-
-
Horio, T.1
Suzuki, M.2
Suzuki, K.3
Takamisawa, I.4
Hiuge, A.5
Kamide, K.6
Takiuchi, S.7
Iwashima, Y.8
Kihara, S.9
Funahashi, T.10
Yoshimasa, Y.11
Kawano, Y.12
-
22
-
-
33645860825
-
Reactive oxygen species have a causal role in multiple forms of insulin resistance
-
Houstis N, Rosen ED, Lander ES. Reactive oxygen species have a causal role in multiple forms of insulin resistance. Nature 2006: 440: 944-948
-
(2006)
Nature
, vol.440
, pp. 944-948
-
-
Houstis, N.1
Rosen, E.D.2
Lander, E.S.3
-
23
-
-
33644784921
-
Increased myocardial oxygen consumption reduces cardiac efficiency in diabetic mice
-
How OJ, Aasum E, Severson DL, Chan WY, Essop MF, Larsen TS. Increased myocardial oxygen consumption reduces cardiac efficiency in diabetic mice. Diabetes 2006; 55: 466-473
-
(2006)
Diabetes
, vol.55
, pp. 466-473
-
-
How, O.J.1
Aasum, E.2
Severson, D.L.3
Chan, W.Y.4
Essop, M.F.5
Larsen, T.S.6
-
24
-
-
0041357130
-
Minimally invasive aortic banding in mice: Effects of altered cardiomyocyte insulin signaling during pressure overload
-
Hu P, Zhang D, Swenson L, Chakrabarti G, Abel ED, Litwin SE. Minimally invasive aortic banding in mice: effects of altered cardiomyocyte insulin signaling during pressure overload. Am J Physiol Heart Circ Physiol 2003; 285: H1261-H1269
-
(2003)
Am J Physiol Heart Circ Physiol
, vol.285
-
-
Hu, P.1
Zhang, D.2
Swenson, L.3
Chakrabarti, G.4
Abel, E.D.5
Litwin, S.E.6
-
25
-
-
0033578604
-
Muscle-specific overexpression of FAT/CD36 enhances fatty acid oxidation by contracting muscle, reduces plasma triglycerides and fatty acids, and increases plasma glucose and insulin
-
Ibrahimi A, Bonen A, Blinn WD, Hajri T, Li X, Zhong K, Cameron R, Abumrad NA. Muscle-specific overexpression of FAT/CD36 enhances fatty acid oxidation by contracting muscle, reduces plasma triglycerides and fatty acids, and increases plasma glucose and insulin. J Biol Chem 1999; 274: 26761-26766
-
(1999)
J Biol Chem
, vol.274
, pp. 26761-26766
-
-
Ibrahimi, A.1
Bonen, A.2
Blinn, W.D.3
Hajri, T.4
Li, X.5
Zhong, K.6
Cameron, R.7
Abumrad, N.A.8
-
26
-
-
0036750019
-
Is creatine kinase a target for AMP-activated protein kinase in the heart?
-
Ingwall JS. Is creatine kinase a target for AMP-activated protein kinase in the heart? J Mol Cell Cardiol 2002; 34: 1111-1120
-
(2002)
J Mol Cell Cardiol
, vol.34
, pp. 1111-1120
-
-
JS, I.1
-
27
-
-
3342967512
-
Is the failing heart energy starved? On using chemical energy to support cardiac function
-
Ingwall JS, Weiss RG. Is the failing heart energy starved? On using chemical energy to support cardiac function. Circ Res 2004: 95: 135-145
-
(2004)
Circ Res
, vol.95
, pp. 135-145
-
-
Ingwall, J.S.1
Weiss, R.G.2
-
28
-
-
0036788287
-
Independent association of type 2 diabetes and coronary artery disease with myocardial insulin resistance
-
Iozzo P, Chareonthaitawee P, Dutka D, Betteridge DJ, Ferrannini E, Camici PG. Independent association of type 2 diabetes and coronary artery disease with myocardial insulin resistance. Diabetes 2002; 51: 3020-3024
-
(2002)
Diabetes
, vol.51
, pp. 3020-3024
-
-
Iozzo, P.1
Chareonthaitawee, P.2
Dutka, D.3
Betteridge, D.J.4
Ferrannini, E.5
Camici, P.G.6
-
29
-
-
0035810983
-
Glycemic control and heart failure among adult patients with diabetes
-
Iribarren C, Karter AJ, Go AS, Ferrara A, Liu JY, Sidney S, Selby JV. Glycemic control and heart failure among adult patients with diabetes. Circulation 2001; 103: 2668-2673
-
(2001)
Circulation
, vol.103
, pp. 2668-2673
-
-
Iribarren, C.1
Karter, A.J.2
Go, A.S.3
Ferrara, A.4
Liu, J.Y.5
Sidney, S.6
Selby, J.V.7
-
30
-
-
0036972669
-
Advanced glycation end-products and advanced oxidation protein products in patients with diabetes mellitus
-
Kalousova M, Skrha J, Zima T. Advanced glycation end-products and advanced oxidation protein products in patients with diabetes mellitus. Physiol Res 2002; 51: 597-604
-
(2002)
Physiol Res
, vol.51
, pp. 597-604
-
-
Kalousova, M.1
Skrha, J.2
Zima, T.3
-
31
-
-
0033838655
-
Incidence and epidemiology of heart failure
-
Kannel WB. Incidence and epidemiology of heart failure. Heart Fail Rev 2000; 5: 167-173
-
(2000)
Heart Fail Rev
, vol.5
, pp. 167-173
-
-
WB, K.1
-
32
-
-
0018764335
-
Diabetes and cardiovascular disease. The Framingham study
-
Kannel WB, MacGee DL. Diabetes and cardiovascular disease. The Framingham study. Jama 1979; 241: 2035-2038
-
(1979)
Jama
, vol.241
, pp. 2035-2038
-
-
Kannel, W.B.1
MacGee, D.L.2
-
33
-
-
23944499556
-
Regulation of cardiac malonyl-CoA content fatty acid oxidation during increased cardiac power
-
King KT, Okere IC, Sharma N, Dyck JR, Reszko AE, MacElfresh TA, Kerner J, Chandler MP, Lopaschuk GD, Stanley WC. Regulation of cardiac malonyl-CoA content fatty acid oxidation during increased cardiac power. Am J Physiol Heart Circ Physiol 2005; 289: H1033-H1037
-
(2005)
Am J Physiol Heart Circ Physiol
, vol.289
-
-
King, K.T.1
Okere, I.C.2
Sharma, N.3
Dyck, J.R.4
Reszko, A.E.5
MacElfresh, T.A.6
Kerner, J.7
Chandler, M.P.8
Lopaschuk, G.D.9
Stanley, W.C.10
-
34
-
-
26444485985
-
Long-chain fatty acid uptake and FAT/CD36 translocation in heart and skeletal muscle
-
Koonen DP, Glatz JF, Bonen A, Luiken JJ. Long-chain fatty acid uptake and FAT/CD36 translocation in heart and skeletal muscle. Biochim Biophys Acta 2005; 1736: 163-180
-
(2005)
Biochim Biophys Acta
, vol.1736
, pp. 163-180
-
-
Koonen, D.P.1
Glatz, J.F.2
Bonen, A.3
Luiken, J.J.4
-
35
-
-
0032903774
-
Laarse A van der, Stoel BC, Doombos J, Wall EE van der, Roos A de. Diastolic dysfunction in hypertensive heart disease is associated with altered myocardial metabolism
-
Lamb HJ, Beyerbacht HP, Laarse A van der, Stoel BC, Doombos J, Wall EE van der, Roos A de. Diastolic dysfunction in hypertensive heart disease is associated with altered myocardial metabolism. Circulation 1999; 99: 2261-2267
-
(1999)
Circulation
, vol.99
, pp. 2261-2267
-
-
Lamb, H.J.1
Beyerbacht, H.P.2
-
36
-
-
33644771243
-
Insulin improves myocardial blood flow in patients with type 2 diabetes and coronary artery disease
-
Lautamaki R, Airaksinen KE, Seppanen M, Toikka J, Harkonen R, Luotolahti M, Borra R, Sundell J, Knuuti J, Nuutila P. Insulin improves myocardial blood flow in patients with type 2 diabetes and coronary artery disease. Diabetes 2006; 55: 511-516
-
(2006)
Diabetes
, vol.55
, pp. 511-516
-
-
Lautamaki, R.1
Airaksinen, K.E.2
Seppanen, M.3
Toikka, J.4
Harkonen, R.5
Luotolahti, M.6
Borra, R.7
Sundell, J.8
Knuuti, J.9
Nuutila, P.10
-
37
-
-
0033594980
-
A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: The PPARalpha-null mouse as a model of fatty acid oxidation disorders
-
Leone TC, Weinheimer CJ, Kelly DP. A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: the PPARalpha-null mouse as a model of fatty acid oxidation disorders. Proc Natl Acad Sci USA 1999; 96: 7473-7478
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 7473-7478
-
-
Leone, T.C.1
Weinheimer, C.J.2
Kelly, D.P.3
-
38
-
-
2942726532
-
Signalling components involved in contraction-inducible substrate uptake into cardiac myocytes
-
Luiken JJ, Coort SL, Koonen DP, Bonen A, Glatz JF. Signalling components involved in contraction-inducible substrate uptake into cardiac myocytes. Proc Nutr Soc 2004; 63: 251-258
-
(2004)
Proc Nutr Soc
, vol.63
, pp. 251-258
-
-
Luiken, J.J.1
Coort, S.L.2
Koonen, D.P.3
Bonen, A.4
Glatz, J.F.5
-
39
-
-
2442716271
-
Horst DJ van der, Bonen A, Zorzano A, Giatz JF. Regulation of cardiac long-chain fatty acid and glucose uptake by translocation of substrate transporters
-
Luiken JJ, Coort SL, Koonen DP, Horst DJ van der, Bonen A, Zorzano A, Giatz JF. Regulation of cardiac long-chain fatty acid and glucose uptake by translocation of substrate transporters. Pflugers Arch 2004; 448: 1-15
-
(2004)
Pflugers Arch
, vol.448
, pp. 1-15
-
-
Luiken, J.J.1
Coort, S.L.2
Koonen, D.P.3
-
40
-
-
4143091440
-
-
Monti LD, Landoni C, Setola E, Galluccio E, Lucotti P, Sandoli EP, Origgi A, Lucignani G, Piatti P, Fazio F. Myocardial insulin resistance associated with chronic hypertriglyceridemia and increased FFA levels in Type 2 diabetic patients. Am J Physiol Heart Circ Physiol 2004; 287: H1225-H1231
-
Monti LD, Landoni C, Setola E, Galluccio E, Lucotti P, Sandoli EP, Origgi A, Lucignani G, Piatti P, Fazio F. Myocardial insulin resistance associated with chronic hypertriglyceridemia and increased FFA levels in Type 2 diabetic patients. Am J Physiol Heart Circ Physiol 2004; 287: H1225-H1231
-
-
-
-
41
-
-
8444242276
-
Uncoupling proteins in human heart
-
Murray AJ, Anderson RE, Watson GC, Radda GK, Clarke K. Uncoupling proteins in human heart. Lancet 2004; 364: 1786-1788
-
(2004)
Lancet
, vol.364
, pp. 1786-1788
-
-
Murray, A.J.1
Anderson, R.E.2
Watson, G.C.3
Radda, G.K.4
Clarke, K.5
-
42
-
-
33947239659
-
The failing heart - an engine out of fuel
-
Neubauer S. The failing heart - an engine out of fuel. N Engl J Med 2007; 356: 1140-1151
-
(2007)
N Engl J Med
, vol.356
, pp. 1140-1151
-
-
Neubauer, S.1
-
43
-
-
0030819144
-
Myocardial phosphocreatine-to-ATP ratio is a predictor of mortality in patients with dilated cardiomyopathy
-
Neubauer S, Horn M, Cramer M, Harre K, Newell JB, Peters W, Pabst T, Ertl G, Huhn D, Ingwall JS, Kochsiek K. Myocardial phosphocreatine-to-ATP ratio is a predictor of mortality in patients with dilated cardiomyopathy. Circulation 1997; 96: 2190-2196
-
(1997)
Circulation
, vol.96
, pp. 2190-2196
-
-
Neubauer, S.1
Horn, M.2
Cramer, M.3
Harre, K.4
Newell, J.B.5
Peters, W.6
Pabst, T.7
Ertl, G.8
Huhn, D.9
Ingwall, J.S.10
Kochsiek, K.11
-
44
-
-
0029415373
-
Contributions of 31P-magnetic resonance spectroscopy to the understanding of dilated heart muscle disease
-
Neubauer S, Horn M, Pabst T, Godde M, Lubke D, Jilling B, Hahn D, Ertl G. Contributions of 31P-magnetic resonance spectroscopy to the understanding of dilated heart muscle disease. Eur Heart J 1995; 16 (Suppl 0): 115-118
-
(1995)
Eur Heart J
, vol.16
, Issue.SUPPL. 0
, pp. 115-118
-
-
Neubauer, S.1
Horn, M.2
Pabst, T.3
Godde, M.4
Lubke, D.5
Jilling, B.6
Hahn, D.7
Ertl, G.8
-
45
-
-
0026615221
-
31P magnetic resonance spectroscopy in dilated cardiomyopathy and coronary artery disease. Altered cardiac high-energy phosphate metabolism in heart failure
-
Neubauer S, Krahe T, Schindler R, Horn M, Hillenbrand H, Entzeroth C, Mader H, Kromer EP, Riegger GA, Lackner K et al. 31P magnetic resonance spectroscopy in dilated cardiomyopathy and coronary artery disease. Altered cardiac high-energy phosphate metabolism in heart failure. Circulation 1992; 86: 1810-1818
-
(1992)
Circulation
, vol.86
, pp. 1810-1818
-
-
Neubauer, S.1
Krahe, T.2
Schindler, R.3
Horn, M.4
Hillenbrand, H.5
Entzeroth, C.6
Mader, H.7
Kromer, E.P.8
Riegger, G.A.9
Lackner, K.10
-
46
-
-
0029946123
-
Aminoguanidine prevents the decreased myocardial compliance produced by streptozotocin-induced diabetes mellitus in rats
-
Norton GR, Candy G, Woodiwiss AJ. Aminoguanidine prevents the decreased myocardial compliance produced by streptozotocin-induced diabetes mellitus in rats. Circulation 1996; 93: 1905-1912
-
(1996)
Circulation
, vol.93
, pp. 1905-1912
-
-
Norton, G.R.1
Candy, G.2
Woodiwiss, A.J.3
-
47
-
-
34547957993
-
Postprandial hyperglycemia/hyperlipidemia (postprandial dysmetabolism) is a cardiovascular risk factor
-
O'Keefe JH, Bell DS. Postprandial hyperglycemia/hyperlipidemia (postprandial dysmetabolism) is a cardiovascular risk factor. Am J Cardiol 2007; 100: 899-904
-
(2007)
Am J Cardiol
, vol.100
, pp. 899-904
-
-
O'Keefe, J.H.1
Bell, D.S.2
-
48
-
-
0014933716
-
Effect of fatty acids on contractility and rhythm of the heart
-
Opie LH. Effect of fatty acids on contractility and rhythm of the heart. Nature 1970; 227: 1055-1056
-
(1970)
Nature
, vol.227
, pp. 1055-1056
-
-
LH, O.1
-
49
-
-
0037199390
-
Impaired myocardial fatty acid oxidation and reduced protein expression of retinoid X receptor-alpha in pacing-induced heart failure
-
Osorio JC, Stanley WC, Linke A, Castellari M, Diep QN, Panchal AR, Hintze TH, Lopaschuk GD, Recchia FA. Impaired myocardial fatty acid oxidation and reduced protein expression of retinoid X receptor-alpha in pacing-induced heart failure. Circulation 2002; 106: 606-612
-
(2002)
Circulation
, vol.106
, pp. 606-612
-
-
Osorio, J.C.1
Stanley, W.C.2
Linke, A.3
Castellari, M.4
Diep, Q.N.5
Panchal, A.R.6
Hintze, T.H.7
Lopaschuk, G.D.8
Recchia, F.A.9
-
50
-
-
0030669392
-
A molecular basis for insulin resistance. Elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxta-membrane region of the insulin receptor and impairs their ability to undergo insulin-induced tyrosine phosphorylation
-
Paz K, Hemi R, LeRoith D, Karasik A, Elhanany E, Kanety H, Zick Y. A molecular basis for insulin resistance. Elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxta-membrane region of the insulin receptor and impairs their ability to undergo insulin-induced tyrosine phosphorylation. J Biol Chem 1997; 272: 29911-29918
-
(1997)
J Biol Chem
, vol.272
, pp. 29911-29918
-
-
Paz, K.1
Hemi, R.2
LeRoith, D.3
Karasik, A.4
Elhanany, E.5
Kanety, H.6
Zick, Y.7
-
51
-
-
2442492971
-
Effect of obesity and insulin resistance on myocardial substrate metabolism and efficiency in young women
-
Peterson LR, Herrero P, Schechtman XB, Racette SB, Waggoner AD, Kisrieva-Ware Z, Dence C, Klein S, Marsala J, Meyer T, Gropler RJ. Effect of obesity and insulin resistance on myocardial substrate metabolism and efficiency in young women. Circulation 2004; 109: 2191-2196
-
(2004)
Circulation
, vol.109
, pp. 2191-2196
-
-
Peterson, L.R.1
Herrero, P.2
Schechtman, X.B.3
Racette, S.B.4
Waggoner, A.D.5
Kisrieva-Ware, Z.6
Dence, C.7
Klein, S.8
Marsala, J.9
Meyer, T.10
Gropler, R.J.11
-
52
-
-
0035846554
-
Metabolic gene expression in fetal and failing human heart
-
Razeghi P, Young ME, Alcorn JL, Moravec CS, Frazier OH, Taegtmeyer H. Metabolic gene expression in fetal and failing human heart. Circulation 2001; 104: 2923-2931
-
(2001)
Circulation
, vol.104
, pp. 2923-2931
-
-
Razeghi, P.1
Young, M.E.2
Alcorn, J.L.3
Moravec, C.S.4
Frazier, O.H.5
Taegtmeyer, H.6
-
53
-
-
0031786420
-
Role of oxygen derived radicals for vascular dysfunction in the diabetic heart: Prevention by alpha-tocopherol?
-
Rosen P, Du X, Tschope D. Role of oxygen derived radicals for vascular dysfunction in the diabetic heart: prevention by alpha-tocopherol? Mol Cell Biochem 1998; 188: 103-111
-
(1998)
Mol Cell Biochem
, vol.188
, pp. 103-111
-
-
Rosen, P.1
Du, X.2
Tschope, D.3
-
54
-
-
0035144307
-
Insulin/IGF-1 and TNF-alpha stimulate phosphorylation of IRS-1 at inhibitory Ser307 via distinct pathways
-
Rui L, Aguirre V, Kim JK, Shulman GI, Lee A, Corbould A, Dunaif A, White MF. Insulin/IGF-1 and TNF-alpha stimulate phosphorylation of IRS-1 at inhibitory Ser307 via distinct pathways. J Clin Invest 2001; 107: 181-189
-
(2001)
J Clin Invest
, vol.107
, pp. 181-189
-
-
Rui, L.1
Aguirre, V.2
Kim, J.K.3
Shulman, G.I.4
Lee, A.5
Corbould, A.6
Dunaif, A.7
White, M.F.8
-
55
-
-
33646347106
-
Cardiac PPARalpha expression in patients with dilated cardiomyopathy
-
Schupp M, Kintscher U, Fielitz J, Thomas J, Pregla R, Hetzer R, Unger T, Regitz-Zagrosek V. Cardiac PPARalpha expression in patients with dilated cardiomyopathy. Eur J Heart Fail 2006; 8: 290-294
-
(2006)
Eur J Heart Fail
, vol.8
, pp. 290-294
-
-
Schupp, M.1
Kintscher, U.2
Fielitz, J.3
Thomas, J.4
Pregla, R.5
Hetzer, R.6
Unger, T.7
Regitz-Zagrosek, V.8
-
56
-
-
0346271515
-
Insulin resistance in dilated cardiomyopathy
-
Shah A, Shannon RP. Insulin resistance in dilated cardiomyopathy. Rev Cardiovasc Med 2003; 4 (Suppl 6): S50-S57
-
(2003)
Rev Cardiovasc Med
, vol.4
, Issue.SUPPL. 6
-
-
Shah, A.1
Shannon, R.P.2
-
57
-
-
7744234747
-
Intramyocardial lipid accumulation in the failing human heart resembles the lipotoxic rat heart
-
Sharma S, Adrogue JV, Golfman L, Uray I, Lemm J, Youker K, Noon GP, Frazier OH, Taegtmeyer H. Intramyocardial lipid accumulation in the failing human heart resembles the lipotoxic rat heart. Faseb J 2004; 18: 1692-1700
-
(2004)
Faseb J
, vol.18
, pp. 1692-1700
-
-
Sharma, S.1
Adrogue, J.V.2
Golfman, L.3
Uray, I.4
Lemm, J.5
Youker, K.6
Noon, G.P.7
Frazier, O.H.8
Taegtmeyer, H.9
-
58
-
-
0034468736
-
Role of reactive oxygen species (ROS) in apoptosis induction
-
Simon HU, Haj-Yehia A, Levi-Schaffer F. Role of reactive oxygen species (ROS) in apoptosis induction. Apoptosis 2000; 5: 415-418
-
(2000)
Apoptosis
, vol.5
, pp. 415-418
-
-
Simon, H.U.1
Haj-Yehia, A.2
Levi-Schaffer, F.3
-
59
-
-
33644876781
-
Epidemiology and etiology of cardiomyopathy in Africa
-
Sliwa K, Damasceno A, Mayosi BM. Epidemiology and etiology of cardiomyopathy in Africa. Circulation 2005; 112: 3577-3583
-
(2005)
Circulation
, vol.112
, pp. 3577-3583
-
-
Sliwa, K.1
Damasceno, A.2
Mayosi, B.M.3
-
61
-
-
0034641568
-
Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): Prospective observational study
-
Stratton IM, Adler AI, Neil HA Matthews DR, Manley SE, Cull CA, Hadden D, Turner RC, Holman RR. Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study. Bmj 2000; 321: 405-412
-
(2000)
Bmj
, vol.321
, pp. 405-412
-
-
Stratton, I.M.1
Adler, A.I.2
Neil, H.A.3
Matthews, D.R.4
Manley, S.E.5
Cull, C.A.6
Hadden, D.7
Turner, R.C.8
Holman, R.R.9
-
63
-
-
0037109183
-
Switching metabolic genes to build a better heart
-
Taegtmeyer H. Switching metabolic genes to build a better heart. Circulation 2002; 106: 2043-2045
-
(2002)
Circulation
, vol.106
, pp. 2043-2045
-
-
Taegtmeyer, H.1
-
64
-
-
0037046203
-
Adaptation and maladaptation of the heart in diabetes: Part I: general concepts
-
Taegtmeyer H, MacNulty P, Young ME. Adaptation and maladaptation of the heart in diabetes: Part I: general concepts. Circulation 2002; 105: 1727-1733
-
(2002)
Circulation
, vol.105
, pp. 1727-1733
-
-
Taegtmeyer, H.1
MacNulty, P.2
Young, M.E.3
-
65
-
-
0021945547
-
Defective energy metabolism of the heart in diabetes
-
Taegtmeyer H, Passmore JM. Defective energy metabolism of the heart in diabetes. Lancet 1985; 1: 139-141
-
(1985)
Lancet
, vol.1
, pp. 139-141
-
-
Taegtmeyer, H.1
Passmore, J.M.2
-
66
-
-
33244464562
-
Critical nodes in signalling pathways: Insights into insulin action
-
Taniguchi CM, Emanuelli B, Kahn CR. Critical nodes in signalling pathways: insights into insulin action. Nat Rev Mol Cell Biol 2006; 7: 85-96
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 85-96
-
-
Taniguchi, C.M.1
Emanuelli, B.2
Kahn, C.R.3
-
67
-
-
0037343188
-
Contribution of fatty acids released from lipolysis of plasma triglycerides to total plasma fatty acid flux and tissue-specific fatty acid uptake
-
Teusink B, Voshol PJ, Dahlmans VE, Rensen PC, Pijl H, Romijn JA, Havekes LM. Contribution of fatty acids released from lipolysis of plasma triglycerides to total plasma fatty acid flux and tissue-specific fatty acid uptake. Diabetes 2003; 52: 614-620
-
(2003)
Diabetes
, vol.52
, pp. 614-620
-
-
Teusink, B.1
Voshol, P.J.2
Dahlmans, V.E.3
Rensen, P.C.4
Pijl, H.5
Romijn, J.A.6
Havekes, L.M.7
-
68
-
-
0001023999
-
Studies on myocardial metabolism. IV. Myocardial metabolism in diabetes
-
Ungar I, Gilbert M, Siegel A, Blain JM, Bing RJ. Studies on myocardial metabolism. IV. Myocardial metabolism in diabetes. Am J Med 1955; 18: 385-396
-
(1955)
Am J Med
, vol.18
, pp. 385-396
-
-
Ungar, I.1
Gilbert, M.2
Siegel, A.3
Blain, J.M.4
Bing, R.J.5
-
69
-
-
37349080234
-
-
Heerebeek L van, Hamdani N, Handoko ML, Falcao-Pires I, Musters RJ, Kupreishvili K, Ijsselmuiden AJ, Schalkwijk CG, Bronzwaer JG, Diamant M, Borbely A, Velden J van der, Stienen GJ, Laarman GJ, Niessen HW, Paulus WJ. Diastolic stiffness of the failing diabetic heart: importance of fibrosis, advanced glycation end products, and myocyte resting tension. Circulation 2008; 117: 43-51
-
Heerebeek L van, Hamdani N, Handoko ML, Falcao-Pires I, Musters RJ, Kupreishvili K, Ijsselmuiden AJ, Schalkwijk CG, Bronzwaer JG, Diamant M, Borbely A, Velden J van der, Stienen GJ, Laarman GJ, Niessen HW, Paulus WJ. Diastolic stiffness of the failing diabetic heart: importance of fibrosis, advanced glycation end products, and myocyte resting tension. Circulation 2008; 117: 43-51
-
-
-
-
70
-
-
0141671792
-
Molecular and physiologic actions of insulin related to production of nitric oxide in vascular endothelium
-
Vincent MA, Montagnani M, Quon MJ. Molecular and physiologic actions of insulin related to production of nitric oxide in vascular endothelium. Curr Diab Rep 2003; 3: 279-288
-
(2003)
Curr Diab Rep
, vol.3
, pp. 279-288
-
-
Vincent, M.A.1
Montagnani, M.2
Quon, M.J.3
-
71
-
-
0028123087
-
Creatine metabolism and the consequences of creatine depletion in muscle
-
Wyss M, Wallimann T. Creatine metabolism and the consequences of creatine depletion in muscle. Mol Cell Biochem 1994; 133-134: 51-66
-
(1994)
Mol Cell Biochem
-
-
Wyss, M.1
Wallimann, T.2
-
72
-
-
0037316670
-
Lipoprotein lipase (LpL) on the surface of cardiomyocytes increases lipid uptake and produces a cardiomyopathy
-
Yagyu H, Chen G, Yokoyama M, Hirata K, Augustus A, Kako Y, Seo T, Hu Y, Lutz EP, Merkel M, Bensadoun A, Homma S, Goldberg IJ. Lipoprotein lipase (LpL) on the surface of cardiomyocytes increases lipid uptake and produces a cardiomyopathy. J Clin Invest 2003; 111: 419-426
-
(2003)
J Clin Invest
, vol.111
, pp. 419-426
-
-
Yagyu, H.1
Chen, G.2
Yokoyama, M.3
Hirata, K.4
Augustus, A.5
Kako, Y.6
Seo, T.7
Hu, Y.8
Lutz, E.P.9
Merkel, M.10
Bensadoun, A.11
Homma, S.12
Goldberg, I.J.13
-
73
-
-
0037117651
-
Adaptation and maladaptation of the heart in diabetes: Part II: potential mechanisms
-
Young ME, MacNulty P, Taegtmeyer H. Adaptation and maladaptation of the heart in diabetes: Part II: potential mechanisms. Circulation 2002: 105: 1861-1870
-
(2002)
Circulation
, vol.105
, pp. 1861-1870
-
-
Young, M.E.1
MacNulty, P.2
Taegtmeyer, H.3
-
74
-
-
0035979775
-
Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta
-
Yuan M, Konstantopoulas N, Lee J, Hansen L, Li ZW, Karin M, Shoelson SE. Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta. Science 2001; 293: 1673-1677
-
(2001)
Science
, vol.293
, pp. 1673-1677
-
-
Yuan, M.1
Konstantopoulas, N.2
Lee, J.3
Hansen, L.4
Li, Z.W.5
Karin, M.6
Shoelson, S.E.7
-
75
-
-
0034652225
-
Lipotoxic heart disease in obese rats: Implications for human obesity
-
Zhou YT, Grayburn P, Karim A Shimabukuro M, Higa M, Baetens D, Orci L, Unger RH. Lipotoxic heart disease in obese rats: implications for human obesity. Proc Natl Acad Sci USA 2000: 97: 1784-1789
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 1784-1789
-
-
Zhou, Y.T.1
Grayburn, P.2
Karim, A.3
Shimabukuro, M.4
Higa, M.5
Baetens, D.6
Orci, L.7
Unger, R.H.8
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