A common variant in the 3′UTR of the GRIK4 glutamate receptor gene affects transcript abundance and protects against bipolar disorder

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 39, 2008, Pages 14940-14945

  Pickard, B S ^a   Knight, H M ^a,c   Hamilton, R S ^b   Soares, D C ^a   Walker, R ^c   Boyd, J K F ^a   Machell, J ^a   Maclean, A ^a   McGhee, K A ^a   Condie, A ^a   Porteous, D J ^a   St Clair, D ^d   Davis, I ^b   Blackwood, D H R ^c   Muir, W J ^c  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

^d UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

Case control association; Hippocampus; Indel; Mental illness; RNA structure

Indexed keywords

GLUTAMATE RECEPTOR; GRIK4; KAINIC ACID RECEPTOR; MESSENGER RNA; UNCLASSIFIED DRUG; GRIK4 PROTEIN, HUMAN;

3' UNTRANSLATED REGION; ALLELE; ANIMAL CELL; ARTICLE; BIPOLAR DISORDER; CASE CONTROL STUDY; CONTROLLED STUDY; EMBRYO; GENE; GENE DELETION; GENE INSERTION; HAPLOTYPE; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MOUSE; NONHUMAN; PREDICTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECONDARY STRUCTURE; RNA TRANSCRIPTION; AMINO ACID SEQUENCE; CHEMISTRY; CONFORMATION; GENETIC TRANSCRIPTION; GENETICS; HETEROZYGOTE; INSERTION DELETION MUTATION; MOLECULAR GENETICS; SINGLE NUCLEOTIDE POLYMORPHISM;

3' UNTRANSLATED REGIONS; ALLELES; AMINO ACID SEQUENCE; BIPOLAR DISORDER; HAPLOTYPES; HETEROZYGOTE; HUMANS; INDEL MUTATION; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, KAINIC ACID; SEQUENCE DELETION; TRANSCRIPTION, GENETIC;

EID: 54449094448     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0800643105     Document Type: Article

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