A transient inhibition of mitochondrial ATP synthesis by nitric oxide synthase activation triggered apoptosis in primary cortical neurons

Journal of Neurochemistry

Volumn 77, Issue 2, 2001, Pages 676-690

  Almeida, Angeles ^a   Bolaños, Juan P ^b  

^a HOSPITAL UNIVERSITARIO DE SALAMANCA   (Spain)

^b UNIVERSITY OF SALAMANCA   (Spain)

Author keywords

Apoptosis; Glutamate; Glutathione; Mitochondria; Necrosis; Nitric oxide

Indexed keywords

ADENOSINE TRIPHOSPHATE; EGTAZIC ACID; GLUTAMATE RECEPTOR; GLUTAMIC ACID; GLUTATHIONE; GLUTATHIONE TRANSFERASE; N METHYL DEXTRO ASPARTIC ACID; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; RHODAMINE 123; SUCCINATE DEHYDROGENASE;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN MITOCHONDRION; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; INHIBITION KINETICS; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; NERVE CELL EXCITABILITY; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PHOSPHATE METABOLISM; PRIORITY JOURNAL; RAT;

2-AMINO-5-PHOSPHONOVALERATE; ADENOSINE TRIPHOSPHATE; ANIMALS; APOPTOSIS; CARBONYL CYANIDE P-TRIFLUOROMETHOXYPHENYLHYDRAZONE; CELLS, CULTURED; CEREBRAL CORTEX; CYCLOSPORINE; ELECTRON TRANSPORT; ELECTRON TRANSPORT COMPLEX I; ENERGY METABOLISM; ENZYME INHIBITORS; EXCITATORY AMINO ACID ANTAGONISTS; GLUTAMIC ACID; ISOENZYMES; MEMBRANE POTENTIALS; MITOCHONDRIA; MODELS, BIOLOGICAL; NAD; NADH, NADPH OXIDOREDUCTASES; NECROSIS; NERVE TISSUE PROTEINS; NEURONS; NEUROTOXINS; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; OLIGOMYCINS; OMEGA-N-METHYLARGININE; PERMEABILITY; RATS; RATS, WISTAR; RECEPTORS, GLUTAMATE; ROTENONE; SINGLE-BLIND METHOD; SUCCINATE CYTOCHROME C OXIDOREDUCTASE;

ANIMALIA;

EID: 0035048454     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2001.00276.x     Document Type: Article

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