메뉴 건너뛰기




Volumn 7, Issue 10, 2008, Pages 1758-1770

A Protein with similarity to PTEN regulates aggregation territory size by decreasing cyclic AMP pulse size during Dictyostelium discoideum development

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; ONCOPROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTOZOAL PROTEIN;

EID: 54249162031     PISSN: 15359778     EISSN: None     Source Type: Journal    
DOI: 10.1128/EC.00210-08     Document Type: Article
Times cited : (17)

References (70)
  • 1
    • 0028670206 scopus 로고
    • Isolation of Dictyostelium discoideum cytokinesis mutants by restriction enzyme-mediated integration of the blasticidin S resistance marker
    • Adachi, H., T. Hasebe, K. Yoshinaga, T. Ohta, and K. Sutoh. 1994. Isolation of Dictyostelium discoideum cytokinesis mutants by restriction enzyme-mediated integration of the blasticidin S resistance marker. Biochem. Biophys. Res. Commun. 205:1808-1814.
    • (1994) Biochem. Biophys. Res. Commun , vol.205 , pp. 1808-1814
    • Adachi, H.1    Hasebe, T.2    Yoshinaga, K.3    Ohta, T.4    Sutoh, K.5
  • 2
    • 33746002298 scopus 로고    scopus 로고
    • DdPDE4, a novel cAMP-specific phosphodiesterase at the surface of Dictyostelium cells
    • Bader, S., A. Kortholt, H. Snippe, and P. J. Van Haastert. 2006. DdPDE4, a novel cAMP-specific phosphodiesterase at the surface of Dictyostelium cells. J. Biol. Chem. 281:20018-20026.
    • (2006) J. Biol. Chem , vol.281 , pp. 20018-20026
    • Bader, S.1    Kortholt, A.2    Snippe, H.3    Van Haastert, P.J.4
  • 3
    • 34248163056 scopus 로고    scopus 로고
    • A G protein-coupled receptor with a lipid kinase domain is involved in cell-density sensing
    • Bakthavatsalam, D., D. Brazill, R. H. Gomer, L. Eichinger, F. Rivero, and A. A. Noegel. 2007. A G protein-coupled receptor with a lipid kinase domain is involved in cell-density sensing. Curr. Biol. 17:892-897.
    • (2007) Curr. Biol , vol.17 , pp. 892-897
    • Bakthavatsalam, D.1    Brazill, D.2    Gomer, R.H.3    Eichinger, L.4    Rivero, F.5    Noegel, A.A.6
  • 6
    • 0033180415 scopus 로고    scopus 로고
    • A cell-counting factor regulating structure size in Dictyostelium
    • Brock, D. A., and R. H. Gomer. 1999. A cell-counting factor regulating structure size in Dictyostelium. Genes Dev. 13:1960-1969.
    • (1999) Genes Dev , vol.13 , pp. 1960-1969
    • Brock, D.A.1    Gomer, R.H.2
  • 7
    • 0036679531 scopus 로고    scopus 로고
    • The different components of a multisubunit cell number-counting factor have both unique and overlapping functions
    • Brock, D. A., R. D. Hatton, D. V. Giurgiutiu, B. Scott, R. Ammann, and R. H. Gomer. 2002. The different components of a multisubunit cell number-counting factor have both unique and overlapping functions. Development 129:3657-3668.
    • (2002) Development , vol.129 , pp. 3657-3668
    • Brock, D.A.1    Hatton, R.D.2    Giurgiutiu, D.V.3    Scott, B.4    Ammann, R.5    Gomer, R.H.6
  • 9
    • 33748880630 scopus 로고    scopus 로고
    • A 60-kilodalton protein component of the counting factor complex regulates group size in Dictyostelium discoideum
    • Brock, D. A., W. N. van Egmond, Y. Shamoo, R. D. Hatton, and R. H. Gomer. 2006. A 60-kilodalton protein component of the counting factor complex regulates group size in Dictyostelium discoideum. Eukaryot. Cell 5:1532-1538.
    • (2006) Eukaryot. Cell , vol.5 , pp. 1532-1538
    • Brock, D.A.1    van Egmond, W.N.2    Shamoo, Y.3    Hatton, R.D.4    Gomer, R.H.5
  • 10
    • 0037162285 scopus 로고    scopus 로고
    • Galpha-mediated inhibition of developmental signal response
    • Brzostowski, J. A., C. Johnson, and A. R. Kimmel. 2002. Galpha-mediated inhibition of developmental signal response. Curr. Biol. 12:1199-1208.
    • (2002) Curr. Biol , vol.12 , pp. 1199-1208
    • Brzostowski, J.A.1    Johnson, C.2    Kimmel, A.R.3
  • 11
    • 1842783708 scopus 로고    scopus 로고
    • A G alpha-dependent pathway that antagonizes multiple chemoattractant responses that regulate directional cell movement
    • Brzostowski, J. A., C. A. Parent, and A. R. Kimmel. 2004. A G alpha-dependent pathway that antagonizes multiple chemoattractant responses that regulate directional cell movement. Genes Dev. 18:805-815.
    • (2004) Genes Dev , vol.18 , pp. 805-815
    • Brzostowski, J.A.1    Parent, C.A.2    Kimmel, A.R.3
  • 13
    • 3042780206 scopus 로고    scopus 로고
    • Insights into morphogenesis from a simple developmental system
    • Chisholm, R. L., and R. A. Firtel. 2004. Insights into morphogenesis from a simple developmental system. Nat. Rev. Mol. Cell Biol. 5:531-541.
    • (2004) Nat. Rev. Mol. Cell Biol , vol.5 , pp. 531-541
    • Chisholm, R.L.1    Firtel, R.A.2
  • 14
    • 0033230933 scopus 로고    scopus 로고
    • PAKa, a putative PAK family member, is required for cytokinesis and the regulation of the cytoskeleton in Dictyostelium discoideum cells during chemotaxis
    • Chung, C. Y., and R. A. Firtel. 1999. PAKa, a putative PAK family member, is required for cytokinesis and the regulation of the cytoskeleton in Dictyostelium discoideum cells during chemotaxis. J. Cell Biol. 147:559-576.
    • (1999) J. Cell Biol , vol.147 , pp. 559-576
    • Chung, C.Y.1    Firtel, R.A.2
  • 15
    • 0035449609 scopus 로고    scopus 로고
    • Signaling pathways controlling cell polarity and chemotaxis
    • Chung, C. Y., S. Funamoto, and R. A. Firtel. 2001. Signaling pathways controlling cell polarity and chemotaxis. Trends Biochem. Sci. 26:557-566.
    • (2001) Trends Biochem. Sci , vol.26 , pp. 557-566
    • Chung, C.Y.1    Funamoto, S.2    Firtel, R.A.3
  • 16
    • 0034625002 scopus 로고    scopus 로고
    • Role of Rac in controlling the actin cytoskeleton and chemotaxis in motile cells
    • Chung, C. Y., S. Lee, C. Briscoe, C. Ellsworth, and R. A. Firtel. 2000. Role of Rac in controlling the actin cytoskeleton and chemotaxis in motile cells. Proc. Natl. Acad. Sci. USA 97:5225-5230.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 5225-5230
    • Chung, C.Y.1    Lee, S.2    Briscoe, C.3    Ellsworth, C.4    Firtel, R.A.5
  • 17
    • 0035947085 scopus 로고    scopus 로고
    • Control of cell polarity and chemotaxis by Akt/PKB and PI3 kinase through the regulation of PAKa
    • Chung, C. Y., G. Potikyan, and R. A. Firtel. 2001. Control of cell polarity and chemotaxis by Akt/PKB and PI3 kinase through the regulation of PAKa. Mol. Cell 7:937-947.
    • (2001) Mol. Cell , vol.7 , pp. 937-947
    • Chung, C.Y.1    Potikyan, G.2    Firtel, R.A.3
  • 18
    • 0015042105 scopus 로고
    • Wave propagation in the early stages of aggregation of cellular slime molds
    • Cohen, M. H., and A. Robertson. 1971. Wave propagation in the early stages of aggregation of cellular slime molds. J. Theor. Biol. 31:101-118.
    • (1971) J. Theor. Biol , vol.31 , pp. 101-118
    • Cohen, M.H.1    Robertson, A.2
  • 19
    • 12544249887 scopus 로고    scopus 로고
    • The PI3K-mediated activation of CRAC independently regulates adenylyl cyclase activation and chemotaxis
    • Comer, F. I., C. K. Lippincott, J. J. Masbad, and C. A. Parent. 2005. The PI3K-mediated activation of CRAC independently regulates adenylyl cyclase activation and chemotaxis. Curr. Biol. 15:134-139.
    • (2005) Curr. Biol , vol.15 , pp. 134-139
    • Comer, F.I.1    Lippincott, C.K.2    Masbad, J.J.3    Parent, C.A.4
  • 20
    • 0037205266 scopus 로고    scopus 로고
    • PI 3-kinases and PTEN: How opposites chemoattract
    • Comer, F. I., and C. A. Parent. 2002. PI 3-kinases and PTEN: how opposites chemoattract. Cell 109:541-544.
    • (2002) Cell , vol.109 , pp. 541-544
    • Comer, F.I.1    Parent, C.A.2
  • 21
    • 30044443294 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase activity controls the chemoattractant-mediated activation and adaptation of adenylyl cyclase
    • Comer, F. I., and C. A. Parent. 2006. Phosphoinositide 3-kinase activity controls the chemoattractant-mediated activation and adaptation of adenylyl cyclase. Mol. Biol. Cell 17:357-366.
    • (2006) Mol. Biol. Cell , vol.17 , pp. 357-366
    • Comer, F.I.1    Parent, C.A.2
  • 22
    • 33644513730 scopus 로고    scopus 로고
    • Beyond PTEN mutations: The PI3K pathway as an integrator of multiple inputs during tumorigenesis
    • Cully, M., H. You, A. J. Levine, and T. W. Mak. 2006. Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis. Nat. Rev. Cancer 6:184-192.
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 184-192
    • Cully, M.1    You, H.2    Levine, A.J.3    Mak, T.W.4
  • 24
    • 0024110461 scopus 로고
    • Disruption of Dictyostelium discoideum morphogenesis by overproduction of cAMP phosphodiesterase
    • Faure, M., G. J. Podgorski, J. Franke, and R. H. Kessin. 1988. Disruption of Dictyostelium discoideum morphogenesis by overproduction of cAMP phosphodiesterase. Proc. Natl. Acad. Sci. USA 85:8076-8080.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 8076-8080
    • Faure, M.1    Podgorski, G.J.2    Franke, J.3    Kessin, R.H.4
  • 25
    • 0033924129 scopus 로고    scopus 로고
    • Dictyostelium: A model for regulated cell movement during morphogenesis
    • Firtel, R. A., and R. Meili. 2000. Dictyostelium: a model for regulated cell movement during morphogenesis. Curr. Opin. Genet. Dev. 10:421-427.
    • (2000) Curr. Opin. Genet. Dev , vol.10 , pp. 421-427
    • Firtel, R.A.1    Meili, R.2
  • 26
    • 0024980225 scopus 로고
    • G protein linked signal transduction pathways in development: Dictyostelium as an experimental system
    • Firtel, R. A., P. J. van Haastert, A. R. Kimmel, and P. N. Devreotes. 1989. G protein linked signal transduction pathways in development: Dictyostelium as an experimental system. Cell 58:235-239.
    • (1989) Cell , vol.58 , pp. 235-239
    • Firtel, R.A.1    van Haastert, P.J.2    Kimmel, A.R.3    Devreotes, P.N.4
  • 27
    • 0027212498 scopus 로고
    • Solubilization and purification of enzymatically active glutathione S-transferase (pGEX) fusion proteins
    • Frangioni, J. V., and B. G. Neel. 1993. Solubilization and purification of enzymatically active glutathione S-transferase (pGEX) fusion proteins. Anal. Biochem. 210:179-187.
    • (1993) Anal. Biochem , vol.210 , pp. 179-187
    • Frangioni, J.V.1    Neel, B.G.2
  • 28
    • 0037205265 scopus 로고    scopus 로고
    • Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis
    • Funamoto, S., R. Meili, S. Lee, L. Parry, and R. A. Firtel. 2002. Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis. Cell 109:611-623.
    • (2002) Cell , vol.109 , pp. 611-623
    • Funamoto, S.1    Meili, R.2    Lee, S.3    Parry, L.4    Firtel, R.A.5
  • 29
    • 0035858886 scopus 로고    scopus 로고
    • Role of phosphatidylinositol 3′ kinase and a downstream pleckstrin homology domain-containing protein in controlling chemotaxis in Dictyostelium
    • Funamoto, S., K. Milan, R. Meili, and R. A. Firtel. 2001. Role of phosphatidylinositol 3′ kinase and a downstream pleckstrin homology domain-containing protein in controlling chemotaxis in Dictyostelium. J. Cell Biol. 153:795-810.
    • (2001) J. Cell Biol , vol.153 , pp. 795-810
    • Funamoto, S.1    Milan, K.2    Meili, R.3    Firtel, R.A.4
  • 30
    • 0037031889 scopus 로고    scopus 로고
    • Cells respond to and bind countin, a component of a multisubunit cell number counting factor
    • Gao, T., K. Ehrenman, L. Tang, M. Leippe, D. A. Brock, and R. H. Gomer. 2002. Cells respond to and bind countin, a component of a multisubunit cell number counting factor. J. Biol. Chem. 277:32596-32605.
    • (2002) J. Biol. Chem , vol.277 , pp. 32596-32605
    • Gao, T.1    Ehrenman, K.2    Tang, L.3    Leippe, M.4    Brock, D.A.5    Gomer, R.H.6
  • 31
    • 6344231664 scopus 로고    scopus 로고
    • A cell number counting factor regulates Akt/protein kinase B to regulate Dictyostelium discoideum group size
    • Gao, T., D. Knecht, L. Tang, R. D. Hatton, and R. H. Gomer. 2004. A cell number counting factor regulates Akt/protein kinase B to regulate Dictyostelium discoideum group size. Eukaryot. Cell 3:1176-1184.
    • (2004) Eukaryot. Cell , vol.3 , pp. 1176-1184
    • Gao, T.1    Knecht, D.2    Tang, L.3    Hatton, R.D.4    Gomer, R.H.5
  • 32
  • 33
    • 0016723617 scopus 로고
    • Evidence for the existence of two types of cAMP binding sites in aggregating cells of Dictyostelium discoideum
    • Green, A. A., and P. C. Newell. 1975. Evidence for the existence of two types of cAMP binding sites in aggregating cells of Dictyostelium discoideum. Cell 6:129-136.
    • (1975) Cell , vol.6 , pp. 129-136
    • Green, A.A.1    Newell, P.C.2
  • 34
    • 34247361650 scopus 로고    scopus 로고
    • Chemotaxis in the absence of PIP3 gradients
    • Hoeller, O., and R. R. Kay. 2007. Chemotaxis in the absence of PIP3 gradients. Curr. Biol. 17:813-817.
    • (2007) Curr. Biol , vol.17 , pp. 813-817
    • Hoeller, O.1    Kay, R.R.2
  • 35
    • 0038247883 scopus 로고    scopus 로고
    • Receptor-mediated regulation of PI3Ks confines PI(3,4,5)P3 to the leading edge of chemotaxing cells
    • Huang, Y. E., M. Iijima, C. A. Parent, S. Funamoto, R. A. Firtel, and P. Devreotes. 2003. Receptor-mediated regulation of PI3Ks confines PI(3,4,5)P3 to the leading edge of chemotaxing cells. Mol. Biol. Cell 14:1913-1922.
    • (2003) Mol. Biol. Cell , vol.14 , pp. 1913-1922
    • Huang, Y.E.1    Iijima, M.2    Parent, C.A.3    Funamoto, S.4    Firtel, R.A.5    Devreotes, P.6
  • 36
    • 0037205230 scopus 로고    scopus 로고
    • Tumor suppressor PTEN mediates sensing of chemoattractant gradients
    • Iijima, M., and P. Devreotes. 2002. Tumor suppressor PTEN mediates sensing of chemoattractant gradients. Cell 109:599-610.
    • (2002) Cell , vol.109 , pp. 599-610
    • Iijima, M.1    Devreotes, P.2
  • 37
    • 0036773899 scopus 로고    scopus 로고
    • Temporal and spatial regulation of chemotaxis
    • Iijima, M., Y. E. Huang, and P. Devreotes. 2002. Temporal and spatial regulation of chemotaxis. Dev. Cell 3:469-478.
    • (2002) Dev. Cell , vol.3 , pp. 469-478
    • Iijima, M.1    Huang, Y.E.2    Devreotes, P.3
  • 38
    • 16544378816 scopus 로고    scopus 로고
    • An inverse PCR technique to rapidly isolate the flanking DNA of Dictyostelium insertion mutants
    • Keim, M., R. S. Williams, and A. J. Harwood. 2004. An inverse PCR technique to rapidly isolate the flanking DNA of Dictyostelium insertion mutants. Mol. Biotechnol. 26:221-224.
    • (2004) Mol. Biotechnol , vol.26 , pp. 221-224
    • Keim, M.1    Williams, R.S.2    Harwood, A.J.3
  • 40
    • 0037567299 scopus 로고    scopus 로고
    • The signal to move: D. discoideum go orienteering
    • Kimmel, A. R., and C. A. Parent. 2003. The signal to move: D. discoideum go orienteering. Science 300:1525-1527.
    • (2003) Science , vol.300 , pp. 1525-1527
    • Kimmel, A.R.1    Parent, C.A.2
  • 41
    • 0028287376 scopus 로고
    • Identification of CRAC, a cytosolic regulator required for guanine nucleotide stimulation of adenylyl cyclase in Dictyostelium
    • Lilly, P. J., and P. N. Devreotes. 1994. Identification of CRAC, a cytosolic regulator required for guanine nucleotide stimulation of adenylyl cyclase in Dictyostelium. J. Biol. Chem. 269:14123-14129.
    • (1994) J. Biol. Chem , vol.269 , pp. 14123-14129
    • Lilly, P.J.1    Devreotes, P.N.2
  • 42
    • 0028978605 scopus 로고
    • Chemoattractant and GTP gamma S-mediated stimulation of adenylyl cyclase in Dictyostelium requires translocation of CRAC to membranes
    • Lilly, P. J., and P. N. Devreotes. 1995. Chemoattractant and GTP gamma S-mediated stimulation of adenylyl cyclase in Dictyostelium requires translocation of CRAC to membranes. J. Cell Biol. 129:1659-1665.
    • (1995) J. Cell Biol , vol.129 , pp. 1659-1665
    • Lilly, P.J.1    Devreotes, P.N.2
  • 43
    • 0035881962 scopus 로고    scopus 로고
    • RasC is required for optimal activation of adenylyl cyclase and Akt/PKB during aggregation
    • Lim, C. J., G. B. Spiegelman, and G. Weeks. 2001. RasC is required for optimal activation of adenylyl cyclase and Akt/PKB during aggregation. EMBO J. 20:4490-4499.
    • (2001) EMBO J , vol.20 , pp. 4490-4499
    • Lim, C.J.1    Spiegelman, G.B.2    Weeks, G.3
  • 45
    • 34250788809 scopus 로고    scopus 로고
    • AKT/PKB signaling: Navigating downstream
    • Manning, B. D., and L. C. Cantley. 2007. AKT/PKB signaling: navigating downstream. Cell 129:1261-1274.
    • (2007) Cell , vol.129 , pp. 1261-1274
    • Manning, B.D.1    Cantley, L.C.2
  • 46
    • 0029146150 scopus 로고
    • Cloning vectors for the production of proteins in Dictyostelium discoideum
    • Manstein, D. J., H. P. Schuster, P. Morandini, and D. M. Hunt. 1995. Cloning vectors for the production of proteins in Dictyostelium discoideum. Gene 162:129-134.
    • (1995) Gene , vol.162 , pp. 129-134
    • Manstein, D.J.1    Schuster, H.P.2    Morandini, P.3    Hunt, D.M.4
  • 47
    • 0031010050 scopus 로고    scopus 로고
    • Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member
    • McPherron, A. C., A. M. Lawler, and S. J. Lee. 1997. Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member. Nature 387:83-90.
    • (1997) Nature , vol.387 , pp. 83-90
    • McPherron, A.C.1    Lawler, A.M.2    Lee, S.J.3
  • 48
    • 0033560747 scopus 로고    scopus 로고
    • Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium
    • Meili, R., C. Ellsworth, S. Lee, T. B. Reddy, H. Ma, and R. A. Firtel. 1999. Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium. EMBO J. 18:2092-2105.
    • (1999) EMBO J , vol.18 , pp. 2092-2105
    • Meili, R.1    Ellsworth, C.2    Lee, S.3    Reddy, T.B.4    Ma, H.5    Firtel, R.A.6
  • 51
    • 18244378218 scopus 로고    scopus 로고
    • A Dictyostelium homologue of WASP is required for polarized F-actin assembly during chemotaxis
    • Myers, S. A., J. W. Han, Y. Lee, R. A. Firtel, and C. Y. Chung. 2005. A Dictyostelium homologue of WASP is required for polarized F-actin assembly during chemotaxis. Mol. Biol. Cell 16:2191-2206.
    • (2005) Mol. Biol. Cell , vol.16 , pp. 2191-2206
    • Myers, S.A.1    Han, J.W.2    Lee, Y.3    Firtel, R.A.4    Chung, C.Y.5
  • 53
    • 8444247968 scopus 로고    scopus 로고
    • Rac regulation of chemotaxis and morphogenesis in Dictyostelium
    • Park, K. C., F. Rivero, R. Meili, S. Lee, F. Apone, and R. A. Firtel. 2004. Rac regulation of chemotaxis and morphogenesis in Dictyostelium. EMBO J. 23:4177-4189.
    • (2004) EMBO J , vol.23 , pp. 4177-4189
    • Park, K.C.1    Rivero, F.2    Meili, R.3    Lee, S.4    Apone, F.5    Firtel, R.A.6
  • 54
    • 0033636259 scopus 로고    scopus 로고
    • A precise group size in Dictyostelium is generated by a cell-counting factor modulating cell-cell adhesion
    • Roisin-Bouffay, C., W. Jang, D. R. Caprette, and R. H. Gomer. 2000. A precise group size in Dictyostelium is generated by a cell-counting factor modulating cell-cell adhesion. Mol. Cell 6:953-959.
    • (2000) Mol. Cell , vol.6 , pp. 953-959
    • Roisin-Bouffay, C.1    Jang, W.2    Caprette, D.R.3    Gomer, R.H.4
  • 55
    • 8444221934 scopus 로고    scopus 로고
    • Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement
    • Sasaki, A. T., C. Chun, K. Takeda, and R. A. Firtel. 2004. Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement. J. Cell Biol. 167:505-518.
    • (2004) J. Cell Biol , vol.167 , pp. 505-518
    • Sasaki, A.T.1    Chun, C.2    Takeda, K.3    Firtel, R.A.4
  • 56
    • 0030448648 scopus 로고    scopus 로고
    • Developmental signal transduction pathways uncovered by genetic suppressors
    • Shaulsky, G., R. Escalante, and W. F. Loomis. 1996. Developmental signal transduction pathways uncovered by genetic suppressors. Proc. Natl. Acad. Sci. USA 93:15260-15265.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 15260-15265
    • Shaulsky, G.1    Escalante, R.2    Loomis, W.F.3
  • 57
    • 0001019046 scopus 로고    scopus 로고
    • YakA, a protein kinase required for the transition from growth to development in Dictyostelium
    • Souza, G. M., S. Lu, and A. Kuspa. 1998. YakA, a protein kinase required for the transition from growth to development in Dictyostelium. Development 125:2291-2302.
    • (1998) Development , vol.125 , pp. 2291-2302
    • Souza, G.M.1    Lu, S.2    Kuspa, A.3
  • 60
    • 0027217068 scopus 로고
    • A transformation vector for Dictyostelium discoideum with a new selectable marker bsr
    • Sutoh, K. 1993. A transformation vector for Dictyostelium discoideum with a new selectable marker bsr. Plasmid 30:150-154.
    • (1993) Plasmid , vol.30 , pp. 150-154
    • Sutoh, K.1
  • 61
    • 0032486198 scopus 로고    scopus 로고
    • Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN
    • Tamura, M., J. Gu, K. Matsumoto, S. Aota, R. Parsons, and K. M. Yamada. 1998. Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN. Science 280:1614-1617.
    • (1998) Science , vol.280 , pp. 1614-1617
    • Tamura, M.1    Gu, J.2    Matsumoto, K.3    Aota, S.4    Parsons, R.5    Yamada, K.M.6
  • 62
    • 0035920111 scopus 로고    scopus 로고
    • A cell number-counting factor regulates group size in Dictyostelium by differentially modulating cAMP-induced cAMP and cGMP pulse sizes
    • Tang, L., R. Ammann, T. Gao, and R. H. Gomer. 2001. A cell number-counting factor regulates group size in Dictyostelium by differentially modulating cAMP-induced cAMP and cGMP pulse sizes. J. Biol. Chem. 276:27663-27669.
    • (2001) J. Biol. Chem , vol.276 , pp. 27663-27669
    • Tang, L.1    Ammann, R.2    Gao, T.3    Gomer, R.H.4
  • 64
    • 0034704106 scopus 로고    scopus 로고
    • Myostatin, a negative regulator of muscle growth, functions by inhibiting myoblast proliferation
    • Thomas, M., B. Langley, C. Berry, M. Sharma, S. Kirk, J. Bass, and R. Kambadur. 2000. Myostatin, a negative regulator of muscle growth, functions by inhibiting myoblast proliferation. J. Biol. Chem. 275:40235-40243.
    • (2000) J. Biol. Chem , vol.275 , pp. 40235-40243
    • Thomas, M.1    Langley, B.2    Berry, C.3    Sharma, M.4    Kirk, S.5    Bass, J.6    Kambadur, R.7
  • 65
    • 0035809177 scopus 로고    scopus 로고
    • Tortoise, a novel mitochondrial protein, is required for directional responses of Dictyostelium in chemotactic gradients
    • van Es, S., D. Wessels, D. R. Soll, J. Borleis, and P. N. Devreotes. 2001. Tortoise, a novel mitochondrial protein, is required for directional responses of Dictyostelium in chemotactic gradients. J. Cell Biol. 152:621-632.
    • (2001) J. Cell Biol , vol.152 , pp. 621-632
    • van Es, S.1    Wessels, D.2    Soll, D.R.3    Borleis, J.4    Devreotes, P.N.5
  • 66
    • 33750141743 scopus 로고    scopus 로고
    • Analysis of signal transduction: Formation of cAMP, cGMP, and Ins(1,4,5)P3 in vivo and in vitro
    • Van Haastert, P. J. 2006. Analysis of signal transduction: formation of cAMP, cGMP, and Ins(1,4,5)P3 in vivo and in vitro. Methods Mol. Biol. 346:369-392.
    • (2006) Methods Mol. Biol , vol.346 , pp. 369-392
    • Van Haastert, P.J.1
  • 67
    • 34249873508 scopus 로고    scopus 로고
    • Essential role of PI3-kinase and phospholipase A2 in Dictyostelium discoideum chemotaxis
    • van Haastert, P. J., I. Keizer-Gunnink, and A. Kortholt. 2007. Essential role of PI3-kinase and phospholipase A2 in Dictyostelium discoideum chemotaxis. J. Cell Biol. 177:809-816.
    • (2007) J. Cell Biol , vol.177 , pp. 809-816
    • van Haastert, P.J.1    Keizer-Gunnink, I.2    Kortholt, A.3
  • 68
    • 0027058315 scopus 로고
    • cAMP-induced desensitization of surface cAMP receptors in Dictyostelium: Different second messengers mediate receptor phosphorylation, loss of ligand binding, degradation of receptor, and reduction of receptor mRNA levels
    • Van Haastert, P. J., M. Wang, A. A. Bominaar, P. N. Devreotes, and P. Schaap. 1992. cAMP-induced desensitization of surface cAMP receptors in Dictyostelium: different second messengers mediate receptor phosphorylation, loss of ligand binding, degradation of receptor, and reduction of receptor mRNA levels. Mol. Biol. Cell 3:603-612.
    • (1992) Mol. Biol. Cell , vol.3 , pp. 603-612
    • Van Haastert, P.J.1    Wang, M.2    Bominaar, A.A.3    Devreotes, P.N.4    Schaap, P.5
  • 69
    • 0036895736 scopus 로고    scopus 로고
    • Loss of myostatin attenuates severity of muscular dystrophy in mdx mice
    • Wagner, K. R., A. C. McPherron, N. Winik, and S. J. Lee. 2002. Loss of myostatin attenuates severity of muscular dystrophy in mdx mice. Ann. Neurol. 52:832-836.
    • (2002) Ann. Neurol , vol.52 , pp. 832-836
    • Wagner, K.R.1    McPherron, A.C.2    Winik, N.3    Lee, S.J.4
  • 70
    • 0030849454 scopus 로고    scopus 로고
    • Regulation of actin polymerization in cell-free systems by GTPgammaS and Cdc42
    • Zigmond, S. H., M. Joyce, J. Borleis, G. M. Bokoch, and P. N. Devreotes. 1997. Regulation of actin polymerization in cell-free systems by GTPgammaS and Cdc42. J. Cell Biol. 138:363-374.
    • (1997) J. Cell Biol , vol.138 , pp. 363-374
    • Zigmond, S.H.1    Joyce, M.2    Borleis, J.3    Bokoch, G.M.4    Devreotes, P.N.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.