Gα-mediated inhibition of developmental signal response

Current Biology

Volumn 12, Issue 14, 2002, Pages 1199-1208

  Brzostowski, Joseph A ^a   Johnson, Cynthia ^a   Kimmel, Alan R ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DICTYOSTELIUM; EUKARYOTA; FUNGI;

CYCLIC AMP; GUANINE NUCLEOTIDE BINDING PROTEIN;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; CHEMISTRY; DICTYOSTELIUM; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MOLECULAR GENETICS; MULTIGENE FAMILY; PHYSIOLOGY; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; CYCLIC AMP; DICTYOSTELIUM; GTP-BINDING PROTEINS; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION;

EID: 0037162285     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(02)00953-3     Document Type: Article

References (41)

1. Molecular tinkering of G protein-coupled receptors: An evolutionary success
2. Integration of signaling networks that regulate Dictyostelium differentiation
3. A cell's sense of direction
4. Signaling pathways controlling cell polarity and chemotaxis
5. Adenosine 3′,5′-monophosphate waves in Dictyostelium discoideum: A demonstration by isotope dilution-fluorography
6. The molecular genetics of chemotaxis: Sensing and responding to chemoattractant gradients
7. Signaling at zero G: G-protein-independent functions for 7-TM receptors
8. G protein signaling events are activated at the leading edge of chemotactic cells
9. Cyclic 3′,5′ AMP relay in Dictyostelium discoideum. I. A technique to monitor responses to controlled stimuli
10. A G-protein beta-subunit is essential for Dictyostelium development
11. Ggamma in Dictyostelium: Its role in localization of gbetagamma to the membrane is required for chemotaxis in shallow gradients
12. The G alpha subunit G alpha 4 couples to pterin receptors and identifies a signaling pathway that is essential for multicellular development in Dictyostelium
13. Regulation and function of G alpha protein subunits in Dictyostelium
14. Receptor-mediated activation of heterotrimeric G-proteins in living cells
15. Mutations in the Dictyostelium heterotrimeric G protein alpha subunit G alpha5 alter the kinetics of tip morphogenesis
16. G alpha 3 regulates the cAMP signaling system in Dictyostelium
17. Cell density sensing mediated by a G protein-coupled receptor activating phospholipase C
18. The G alpha protein ODR-3 mediates olfactory and nociceptive function and controls cilium morphogenesis in C. elegans olfactory neurons
19. Antagonism between G(o)alpha and G(q)alpha in Caenorhabditis elegans: The RGS protein EAT-16 is necessary for G(o)alpha signaling and regulates G(q)alpha activity
20. Genomic database resources for Dictyostelium discoideum
21. Activated Galpha subunits can inhibit multiple signal transduction pathways during Dictyostelium development
22. The Dictyostelium developmental cDNA project: Generation and analysis of expressed sequence tags from the first-finger stage of development
23. A precise group size in Dictyostelium is generated by a cell-counting factor modulating cell-cell adhesion
24. Different molecular mechanisms for cAMP regulation of gene expression during Dictyostelium development
25. Structural elements of G alpha subunits that interact with G beta gamma, receptors, and effectors
26. Structural and functional relationships of heterotrimeric G-proteins
27. Caffeine blocks activation of cyclic AMP synthesis in Dictyostelium discoideum
28. Adenosine and its derivatives inhibit the cAMP signaling response in Dictyostelium discoideum
29. Cell cycle phase in Dictyostelium discoideum is correlated with the expression of cyclic AMP production, detection, and degradation
30. Cells at the center of Dictyostelium aggregates become spores
31. gdt1, a new signal transduction component for negative regulation of the growth-differentiation transition in Dictyostelium discoideum
32. A mathematical model for chemoattractant gradient sensing based on receptor-regulated membrane phospholipid signaling dynamics
33. A diffusion-translocation model for gradient sensing by chemotactic cells
34. Models of eukaryotic gradient sensing: Application to chemotaxis of amoebae and neutrophils
35. G protein-coupled receptor adaptation mechanisms
36. G protein-coupled receptor kinases
37. Phosphorylation of chemoattractant receptors is not essential for chemotaxis or termination of G-protein-mediated responses
38. Structurally distinct and stage-specific adenylyl cyclase genes play different roles in Dictyostelium development
39. Mammalian RGS proteins: Barbarians at the gate
40. GTPase-activating proteins for heterotrimeric G proteins: Regulators of G protein signaling (RGS) and RGS-like proteins
41. The novel tyrosine kinase ZAK1 activates GSK3 to direct cell fate specification