CpG oligodeoxynucleotides activate grass carp (Ctenopharyngodon idellus) macrophages

Developmental and Comparative Immunology

Volumn 27, Issue 4, 2003, Pages 313-321

  Meng, Zhen ^a   Shao, Jianzhong ^a   Xiang, Lixin ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Acid phosphatase; Activation; Bactericidal activity; CpG motifs; Grass carp; Head kidney macrophages; Hydrogen peroxide; Oligodeoxynucleotides; Superoxide anion

Indexed keywords

ACID PHOSPHATASE; DINUCLEOTIDE; HYDROGEN PEROXIDE; OLIGONUCLEOTIDE; SUPEROXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ATLANTIC SALMON; BACTERICIDAL ACTIVITY; CARP; CELLULAR IMMUNITY; CONTROLLED STUDY; CPG ISLAND; CTENOPHARYNGODON IDELLUS; FISH DISEASE; HOST RESISTANCE; IMMUNOMODULATION; IMMUNOSTIMULATION; KIDNEY CELL; LYMPHOCYTE; MACROPHAGE ACTIVATION; NONHUMAN; NUCLEOTIDE REPEAT; PRIORITY JOURNAL; PROTEIN MOTIF; SEQUENCE ANALYSIS;

BACTERIA (MICROORGANISMS); CTENOPHARYNGODON IDELLA; CYPRINUS CARPIO; SALMO SALAR;

EID: 0037391610     PISSN: 0145305X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0145-305X(02)00104-0     Document Type: Article

References (40)

1. Tokunaga T., Yamamoto H., Shimada S., Abe H., Fukuda T., Fujisawa Y., Furutani Y., Yano O., Kataoka T., Sudo T., Makiguchi N., Suganuma T. Antitumor activity of deoxyribonucleic acid fraction from myobacterium bovis BCG: Isolation, physicochemical characterization, and antitumor activity. J Natl Cancer Inst. 72:1984;955-962.
2. Yamomato S., Kuramoto E., Shimada S., Tokunaga T. In vitro augmentation of natural killer cell activity and production of interferon-α/β and -γ with deoxyribonucleic acid fraction from myobacterium bovis BCG. Jpn J Cancer Res. 79:1988;866-873.
3. Yamomato S., Yamomato T., Shimada S., Kuramoto E., Yano O., Kataoka T., Tokunaga T. DNA from bacteria, but not from vertebrates, induces interferon, activates natural killer cells and inhibits tumor growth. Microbiol Immunol. 36:1992;983-987.
4. Messina J.P., Gilkeson G.S., Pisetsky D.S. Stimulation of in vitro murine lymphocyte proliferation by bacterial DNA. J Immunol. 147:1991;1759-1764.
5. Krieg A.M., Yi A.-K., Matson S., Waldschmidt T.J., Bishop G.A., Teasdale R. CpG motifs in bacterial DNA trigger direct B-cell activation. Nature. 374:1995;546-549.
6. Bird A.P. CpG islands as gene markers in the vertebrate nucleus. Trends Genet. 3:1987;342-347.
7. Jabbari K., Cacciò S., Barros J., Desgrès J., Bernardi G. Evolutionary changes in CpG and methylation levels in the genome of vertebrates. Gene. 205:1997;109-118.
8. Krieg A.M., Wu T., Weeratna R., Efler S.M., Love-Homan L., Yang L., Yi A.-K., Short D., Davis H.L. Sequence motifs in adenoviral DNA block immune activation by stimulatory CpG motifs. PNAS. 95:1998;12631-12636.
9. Davis H.L., Weeratna R., Waldschmidt T.J., Tygrett L., Schorr J., Krieg A.M. CpG DNA is a potent adjuvant in mice immunized with recombinant hepatitis B surface antigen. J Immunol. 160:1998;870-876.
10. Yi A.-K., Klinman D.M., Martin T.L., Matson S., Krieg A.M. Rapid immune activation by CpG motifs in bacterial DNA: systemic induction of IL-6 transcription through an antioxidant-sensitive pathway. J Immunol. 157:1996;5394-5402.
11. Redford T.W., Yi A.-K., Ward C.T., Krieg A.M. Cyclosporine A enhances IL-12 production by CpG motifs in bacterial DNA and synthetic oligodeoxynucleotides. J Immunol. 161:1998;3930-3935.
12. Stacey K.J., Sweet M.J., Hume D.A. Macrophages ingest and are activated by bacterial DNA. J Immunol. 157:1996;2116-2122.
13. Hartmann G., Krieg A.M. CpG DNA and LPS induce distinct patterns of activation in human monocytes. Gene Ther. 6:1999;893-903.
14. Hartmann G., Weiner G., Krieg A.M. CpG DNA as a signal for growth, activation and maturation of human dendritic cells. PNAS. 96:1999;9305-9310.
15. Ballas Z.K., Rasmussen W.L., Krieg A.M. Induction of natural killer activity in murine and human cells by CpG motifs in oligodeoxynucleotides and bacterial DNA. J Immunol. 157:1996;1840-1845.
16. Chace J.H., Hooker N.A., Mildenstein K.L., Krieg A.M., Cowdery J.S. Bacterial DNA-induced NK cell IFN-γ production is dependent on macrophage secretion of IL-12. Clin Immunol Immunopathol. 84:1997;185-193.
17. Jørgensen J.B., Johansen A., Stenersen B., Sommer A.-I. CpG oligodeoxynucleotides and plasmid DNA stimulate Atlantic salmon (salmo salar L.) leucocytes to produce supernatants with antiviral activity. Dev Comp Immunol. 25:2001;313-321.
18. Jørgensen J.B., Zhou J., Johansen A., Secombes C.J. Immunostimulatory CpG oligodeoxynucleotides stimulate expression of IL-1 β and interferon-like cytokines in rainbow trout macrophages via a chloroquine-sensirive mechanism. Fish Shellfish Immunol. 11:2001;673-682.
19. Yi A.K., Tuetken R., Redford T., Waldschmidt M., Kirsch J., Krieg A.M. CpG motifs in bacterial DNA activate leukocytes through the pH-dependent gerneration of reactive oxygen specied. J Immunol. 160:1998;4755-4761.
20. Shao J.Z., Xiang L.X. Immunomodulation function of grass carp (Ctenopharyngodon idellus) interferon. Acta Zool Sinica. 47:2001;404-411.
21. Krieg A.M. The role of CpG motifs in innate immunity. Curr Opin Immunol. 12:2000;35-43.
22. Chung S., Secombes C.J. Activation of rainbow trout macrophages. J Fish Biol. 31:(suppl.):1987;51-56.
23. Chung S., Secombes C.J. Analysis of events occuring with teleost macrophages during the respiratory burst. Comp Biochem Physiol. 89B:1988;539-544.
24. Enane N.A., Frenkel K., Oconnor J.M., Squibb K.S., Zelikoff J.T. Biological markers of macrophage activation: applications for fish phagocytes. Immunology. 80:1993;68-72.
25. Shen J.Y., Chen Y.Y., Shen Z.H., Qian D., Yang C.L. Study on pathogen of outbreaks of infectious disease of fishes in Zhejiang provine. I. Isolation, pathogenicity, physiological and biochemical characteristics of Aeromonas hydrophila. Bull Sci Technol. 9:1993;397-401.
26. Chung S., Jeffries A.H., Secombes C.J. A novel assay to detect macrophage bactericidal activity in fish: factors influencing the killing of Aeromonas salmonicida. J Fish Dis. 11:1988;389-396.
27. Hartmann G., Krieg A.M. Mechanism and function of a newly identified CpG DNA motif in human primary B cells. J Immunol. 164:2000;944-952.
28. Kanellos T.S., Sylvester I.D., Butler V.L., Ambali C.D., Partidos C.D. Mammalian-granulocyte-macrophage colony-stimulating factor and some CpG motifs have an effect on the immunogenicity of DNA and subunit vaccines in fish. Immunology. 96:1999;507-510.
29. Medzhitov R., Janeway C.A. Jr. Innate Immunity: the virtues of nonclonal system of recognition. Cell. 91:1997;295-298.
30. Krieg A.M., Wagner H. Causing a commotion in the blood: immunotherapy progresses from bacteria to bacterial DNA. Immunol Today. 21:2000;521-526.
31. Hemmi H., Takeuchi O., Kawai T., Kaisho T., Sato S., Sanjo H., Matsumoto M., Hoshino K., Wagner H., Takeda K., Akira S. A toll-like receptor recognizes bacterial DNA. Nature. 408:2000;740-745.
32. Yi A.K., Tuetken R., Redford T., Waldschmidt M., Kirsch J., Krieg A.M. CpG motifs in bacterial DNA activate leukocytes through the pH-dependent gerneration of reactive oxygen specied. J Immunol. 160:1998;4755-4761.
33. Weeranta R.D., McCluskie M.J., Xu Y., Davis H.L. CpG ODN induces stronger immune response with less toxicity than other adjuvants. Vaccine. 18:2000;1755-1762.
34. Krieg A.M. Immune effects and mechanisms of action of CpG motifs. Vaccine. 19:2001;618-622.
35. Xu H.L., Wang S.Q., Wang S.F., Guo F., Lu R.J., Ruan L. Evaluation of immunostimulatory activities of human CpG-ODN containing 5′-GTCGTT-3′ motif in murine model. Virus Lett. 17:2001;43-47.
36. Eastoott J.W., Holmberg C.J., Dewhirst F.E., Esch T.R., Smith D.J., Tanbman M.A. Oligodeoxynucleotides containg CpG motifs enhances immune response to mucosally or systematically administrated tetanus toxoid. Vaccine. 19:2001;1636-1642.
37. McCluskie M.J., Weeratna R.D., Davis H.L. The potential if oligodeoxynucleotides as mucosal and parenteral adjuvants. Vaccine. 19:2001;2657-2660.
38. Liu H.M., Newbrough S.E., Bhatia S.K., Dahle C.E., Krieg A.M. Immunostimulatory CpG oligodeoxynucleotides enhance the immune response to vaccine strategies involving granulocyte-macrophage colony-stimulating factor. Blood. 92:1998;3730-3736.
39. Traxler G.S., Anderson E., LaPatra S.E., Richard J., Shewmaker B., Kurath G. Naked DNA vaccination of Atlantic salmon Salmo salar against IHNV. Dis Aqua Org. 38:1999;183-190.
40. Kim C.H., Johnson M.C., Drennan J.D., Simon B.E., Thomann E., Leong J.A.C. DNA vaccines encoding viral glycoproteins induce nonspecific immunity and Mr protein synthesis in fish. J Virology. 74:2000;7048-7054.