Highly cytotoxic and neurotoxic acetogenins of the Annonaceae: New putative biological targets of squamocin detected by activity-based protein profiling

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 21, 2008, Pages 5741-5744

  Derbré, Séverine ^a   Gil, Sophie ^b   Taverna, Myriam ^c   Boursier, Céline ^c   Nicolas, Valérie ^c   Demey Thomas, Emmanuelle ^d   Vinh, Joëlle ^d   Susin, Santos A ^e   Hocquemiller, Reynald ^a   Poupon, Erwan ^a  

^a CNRS   (France)

^b UNIVERSITÉ PARIS SACLAY   (France)

^c IPSIT   (France)

^d Brain Plasticity Unit   (France)

^e INSTITUT PASTEUR   (France)

Author keywords

Acetogenin; Hemisynthesis; Microscopy; Proteomic; Squamocin

Indexed keywords

ACETOGENIN; COPPER; PROTEOME; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SQUAMOCIN;

ANNONACEAE; ARTICLE; CATALYSIS; CYCLOADDITION; DRUG CYTOTOXICITY; DRUG MECHANISM; DRUG POTENCY; NEUROTOXICITY; NONHUMAN; PROTEOMICS; STRUCTURE ACTIVITY RELATION;

ANNONACEAE;

EID: 54049145429     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.09.091     Document Type: Article

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