Remarkable substituent effect: β-aminosquamocin, a potent dual inhibitor of mitochondrial complexes I and III

Biochimica et Biophysica Acta - Bioenergetics

Volumn 1709, Issue 3, 2005, Pages 191-194

  Duval, Romain A ^a   Poupon, Erwan ^a   Brandt, Ulrich ^b   Hocquemiller, Reynald ^a  

^a CNRS   (France)

^b GOETHE UNIVERSITY   (Germany)

Author keywords

Annonaceous acetogenins; Complex I; Complex III; Cytotoxicity; Dual inhibitor; Squamocin

Indexed keywords

ACETOGENIN; AMINE; BETA AMINOSQUAMOCIN; CAPSAICIN; CITRININ; DOXORUBICIN; LACTONE; MYXOTHIAZOL; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); ROTENONE; SQUAMOCIN; UBIQUINOL CYTOCHROME C REDUCTASE; UNCLASSIFIED DRUG;

ARTICLE; DRUG ACTIVITY; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; DRUG TARGETING; ENZYME INHIBITION; HUMAN; INHIBITION KINETICS; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; NONHUMAN; PHARMACOPHORE; PRIORITY JOURNAL; RESPIRATORY SYSTEM; STRUCTURE ACTIVITY RELATION;

EID: 24344499701     PISSN: 00052728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbabio.2005.07.011     Document Type: Article

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