Replacement of the active surface of a thermophile protein by that of a homologous mesophile protein through structure-guided 'protein surface grafting'

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1784, Issue 11, 2008, Pages 1771-1776

  Kapoor, Divya ^a   Kumar, Vijay ^a   Chandrayan, Sanjeev K ^a   Ahmed, Shubbir ^a   Sharma, Swati ^a   Datt, Manish ^a   Singh, Balvinder ^a   Karthikeyan, Subramanian ^a   Guptasarma, Purnananda ^a,b  

^a INSTITUTE OF MICROBIAL TECHNOLOGY   (India)

^b INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH MOHALI   (India)

Author keywords

Beta sheet remodeling; Protein activity remodeling; Protein folding and stability; Protein stability remodeling; Protein surface grafting

Indexed keywords

BACTERIAL PROTEIN; CELLULASE; FUNGAL PROTEIN; SCAFFOLD PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; CELL SURFACE; CONFORMATION; ENZYME ACTIVITY; MELTING POINT; MESOPHILE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ENGINEERING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STABILITY; PROTEIN STRUCTURE; RHODOTHERMUS; SEQUENCE ALIGNMENT; THERMOPHILE; THERMOSTABILITY; TRICHODERMA REESEI;

AMINO ACID SEQUENCE; CATALYTIC DOMAIN; CELLULASES; HYDROGEN-ION CONCENTRATION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN DENATURATION; PROTEIN ENGINEERING; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; RHODOTHERMUS; STRUCTURAL HOMOLOGY, PROTEIN; SURFACE PROPERTIES; TEMPERATURE; THERMODYNAMICS; TRANSITION TEMPERATURE; TRICHODERMA;

HYPOCREA JECORINA; RHODOTHERMUS MARINUS;

EID: 54049143806     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbapap.2008.05.007     Document Type: Article

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