A critical role of the adenosine A2A receptor in extrastriatal neurons in modulating psychomotor activity as revealed by opposite phenotypes of striatum and forebrain A2A receptor knock-outs

Journal of Neuroscience

Volumn 28, Issue 12, 2008, Pages 2970-2975

  Shen, Hai Ying ^a,e   Coelho, Joana E ^a   Ohtsuka, Nobuhisa ^a   Canas, Paula M ^c   Day, Yuan Ji ^b   Huang, Qing Yuan ^a   Rebola, Nelson ^c   Yu, Liqun ^a   Boison, Detlev ^d   Cunha, Rodrigo A ^c   Linden, Joel ^b   Tsien, Joe Z ^a   Chen, Jiang Fan ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

^c UNIVERSITY OF COIMBRA   (Portugal)

^d LEGACY RESEARCH   (United States)

^e THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Adenosine A2A receptor; Cocaine; Forebrain A2AR knock out; PCP; Psychomotor activity; Striatum A2AR knock out

Indexed keywords

ADENOSINE A2A RECEPTOR; COCAINE; CRE RECOMBINASE; ISTRADEFYLLINE; PHENCYCLIDINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; DRUG MECHANISM; DRUG POTENTIATION; FOREBRAIN; GENE DELETION; HIPPOCAMPUS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PSYCHOMOTOR ACTIVITY; WILD TYPE;

ANALYSIS OF VARIANCE; ANIMALS; BEHAVIOR, ANIMAL; COCAINE; CORPUS STRIATUM; DOPAMINE UPTAKE INHIBITORS; ENZYME INHIBITORS; HOMEODOMAIN PROTEINS; MICE; MICE, TRANSGENIC; NEURONS; PHENCYCLIDINE; PROSENCEPHALON; PSYCHOMOTOR PERFORMANCE; PURINES; RECEPTOR, ADENOSINE A2A;

EID: 41149136068     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5255-07.2008     Document Type: Article

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