Nucleus accumbens dopamine depletions make rats more sensitive to high ratio requirements but do not impair primary food reinforcement

Neuroscience

Volumn 92, Issue 2, 1999, Pages 545-552

  Aberman, J E ^a   Salamone, J D ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

Energy; Fixed ratio; Motivation; Motor; Operant; Reward

Indexed keywords

DOPAMINE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CORRELATION FUNCTION; DOPAMINERGIC SYSTEM; ENERGY; INSTRUMENTAL CONDITIONING; MALE; MOTIVATION; MOTOR ACTIVITY; NEUROCHEMISTRY; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAT; REINFORCEMENT; REWARD;

EID: 0033042808     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(99)00004-4     Document Type: Article

References (44)

1. Allison J. (1981) Economics and operant conditioning. In Predictability, Correlation and Contiguity, (eds Harzem P. and Zeiler M. D.), pp. 321-353. John Wiley and Sons, New York.
2. Bakshi V.P., Kelley A.E. Dopaminergic regulation of feeding behavior: I. Differential effects of haloperidol microinjection in three striatal subregions. Psychobiology. 19:1991;223-232.
3. Berridge K.C. Food reward: brain substrates for wanting and liking. Neurosci. Biobehav. Rev. 20:1996;1-25.
4. Bozarth M.A., Wise R.A. Involvement of the ventral tegmental dopamine system in opioid and psychomotor stimulant reinforcement. Life Sci. 28:1981;551-555.
5. Caine S.B., Koob G.F. Effects of mesolimbic dopamine depletion on responding maintained by cocaine and food. J. exp. analyt. Behav. 61:1994;213-221.
6. Cousins M.S., Salamone J.D. Nucleus accumbens dopamine depletions in rats affect relative response allocation in a novel cost/benefit procedure. Pharmac. Biochem. Behav. 49:1994;85-91.
7. Cousins M.S., Sokolowski J.D., Salamone J.D. Different effects of nucleus accumbens and ventrolateral striatal dopamine depletions on instrumental response selection in the rat. Pharmac. Biochem. Behav. 46:1993;943-951.
8. Cousins M.S., Atherton A., Turner L., Salamone J.D. Nucleus accumbens dopamine depletions alter relative response allocation in a T-maze cost/benefit task. Behav. Brain Res. 74:1996;189-197.
9. Cousins M. S., Trevitt J., Atherton A. and Salamone J. D. Different behavioral functions of dopamine in nucleus accumbens and ventrolateral striatum: a microdialysis and behavioral investigation. Neuroscience 91, 925-934.
10. Hernandez L. and Hoebel B. G. (1988) Food reward and cocaine increase extracellular dopamine in the nucleus accumbens as measured by microdialysis. Life Sci. 42, 1705-1712.
11. Hursh S.R., Raslear T.G., Shurtleff D., Bauman R., Simmons L. A cost-benefit analysis of demand for food. J. exp. analyt. Behav. 30:1988;419-440.
12. Kaufman L.W. Foraging cost and meal patterns in ferrets. Physiol. Behav. 25:1980;139-141.
13. Keppel G. (1982) Design and Analysis: A Researchers Handbook. Prentice-Hall, Englewood Cliffs, New Jersey.
14. Koob G.F., Riley S.J., Smith S.C., Robbins T.W. Effects of 6-hydroxydopamine lesions of the nucleus accumbens septi and olfactory tubercle on feeding, locomotor activity, and amphetamine anorexia in the rat. J. comp. Physiol. Psychol. 92:1978;917-927.
15. Krebs J. R. (1978) Optimal foraging: decision rules for predators. In Behavioral Ecology, (eds Krebs J. R. and Davies W. B.). Sinauer Associates, Sunderland, Massachusetts.
16. Lea S.E.G. The psychology and economics of demand. Psychol. Bull. 85:1978;441-466.
17. McCullough L.D., Cousins M.S., Salamone J.D. The role of nucleus accumbens dopamine in responding on a continuous reinforcement operant schedule: a neurochemical and behavioral study. Pharmac. Biochem. Behav. 46:1993;581-586.
18. Neill D. B. and Justice J. B. (1981) A hypothesis for a behavioral function of dopaminergic transmission in nucleus accumbens. In The Neurobiology of the Nucleus Accumbens, (eds Chronister R. B. and Defrance J. F.). Huer Institute, Brunswick, Canada.
19. Rashotte M.E., Henderson D. Coping with rising food costs in a closed economy: feeding behavior and nocturnal hypothermia in pigeons. J. exp. analyt. Behav. 50:1988;441-456.
20. Robbins T.W., Everitt B.J. Neurobehavioral mechanisms of reward and motivation. Curr. Opin. Neurobiol. 6:1996;229-236.
21. Roberts D.C.S., Corcoran M.E., Fibiger H.C. On the role of ascending catecholaminergic systems in intravenous self-administration of cocaine. Pharmac. Biochem. Behav. 6:1977;615-620.
22. Salamone J. D. (1987) The actions of neuroleptic drugs on appetitive instrumental behaviors. In Handbook of Psychopharmacology, (eds Iversen L. L., Iversen S. D. and Snyder S. H.). pp. 575-608, Plenum, New York.
23. Salamone J. D. (1991) Behavioral pharmacology of dopamine systems: a new synthesis. In The Mesolimbic Dopamine System: From Motivation to Action, (eds Willner P. and Scheel-Kruger J.), pp. 599-612. Cambridge University Press, Cambridge, U.K.
24. Salamone J.D. Complex motor and sensorimotor functions of accumbens and striatal dopamine: involvement in instrumental behavior processes. Psychopharmacology. 107:1992;160-174.
25. Salamone J.D., Cousins M.S., Bucher S. Anhedonia or anergia? Effects of haloperidol and nucleus accumbens dopamine depletion on instrumental response selection in a T-maze cost/benefit procedure. Behav. Brain Res. 65:1994;221-229.
26. Salamone J.D., Cousins M.S., Snyder B.J. Behavioral functions of nucleus accumbens dopamine: empirical and conceptual problems with the anhedonia hypothesis. Neurosci. Biobehav. Rev. 21:1997;341-359.
27. Salamone J.D., Kurth P., McCullough L.D., Sokolowski J.D. The effects of nucleus accumbens dopamine depletions on continuously reinforced operant responding: contrasts with the effects of extinction. Pharmac. Biochem. Behav. 50:1995;437-443.
28. Salamone J.D., Kurth P.A., McCullough L.D., Sokolowski J.D., Cousins M.S. The role of brain dopamine in response initiation: effects of haloperidol and regionally-specific dopamine depletions on the local rate of instrumental responding. Brain Res. 628:1993;218-226.
29. Salamone J.D., Mahan K., Rogers S. Ventrolateral striatal dopamine depletions impair feeding and food handling in rats. Pharmac. Biochem. Behav. 44:1993;605-610.
30. Salamone J.D., Steinpreis R.E., McCullough L.D., Smith P., Grebel D., Mahan K. Haloperidol and nucleus accumbens dopamine depletion suppress lever pressing for food but increase free food consumption in a novel food-choice procedure. Psychopharmacology. 104:1991;515-521.
31. Smith G.P. Dopamine and food reward. Prog. Psychobiol. Physiol. Psychol. 16:1995;83-144.
32. Sokolowski J.D., Salamone J.D. The role of nucleus accumbens dopamine in lever pressing and response allocation: effects of 6-OHDA injected into core and dorsomedial shell. Pharmac. Biochem. Behav. 59:1998;557-566.
33. Staddon J.E.R. Operant behavior as adaptation to constraint. J. exp. Psychol. Gen. 108:1979;48-67.
34. Staddon J. E. R. (1983) Adaptive Behavior and Learning. Cambridge University Press, Cambridge, U.K.
35. Staddon J. E. R. and Ettinger R. H. (1989) Learning: An Introduction to the Principles of Adaptive Behavior, pp. 291-292. Harcourt, Brace and Jovanovitch, New York.
36. Szechtman H., Talangbayan H., Ganaran G., Dai H., Eilam D. Dynamics of behavioral sensitization induced by the dopamine agonist quinpirole and a proposed central energy control mechanism. Psychopharmacology. 115:1994;95-104.
37. Thorndike E. L. (1911) Animal Intelligence. Macmillan, New York.
38. Timberlake W. Behavior systems and reinforcement: an integrative approach. J. exp. analyt. Behav. 60:1993;105-128.
39. Timberlake W., Allison J. Response deprivation: an empirical approach to instrumental performance. Psychol. Rev. 81:1974;146-164.
40. Willner P., Chalwa K., Sampson D., Sophokleous S., Muscat R. Tests of functional equivalence between pimozide pretreatment, extinction and free feeding. Psychopharmacology. 95:1988;423-426.
41. Wise R.A. Neuroleptics and operant behavior: the anhedonia hypothesis. Behav. Brain Sci. 5:1982;39-87.
42. Wise R.A., Raptis L. Effects of pre-feeding on food-approach latency and food consumption speed in food deprived rat. Physiol. Behav. 35:1985;961-963.
43. Wise R.A., Spindler J., De Witt H., Gerber G.J. Neuroleptic-induced "anhedonia" in rats: pimozide blocks reward quality of food. Science. 201:1978;262-264.
44. Zahm D.S., Brog J.S. On the significance of subterritories in the "accumbens" part of the rat ventral striatum. Neuroscience. 50:1992;751-767.