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Volumn 29, Issue 11, 2006, Pages 647-654

Targeting adenosine A2A receptors in Parkinson's disease

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE A2A RECEPTOR; ADENOSINE A2A RECEPTOR ANTAGONIST; ANTIPARKINSON AGENT; CAFFEINE; ISTRADEFYLLINE; LEVODOPA; SCH BT 2; UNCLASSIFIED DRUG;

EID: 33750171348     PISSN: 01662236     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tins.2006.09.004     Document Type: Review
Times cited : (400)

References (75)
  • 1
    • 0026437722 scopus 로고
    • 2 receptors in the neostriatum
    • 2 receptors in the neostriatum. Brain Res. 594 (1992) 124-130
    • (1992) Brain Res. , vol.594 , pp. 124-130
    • Ferré, S.1    Fuxe, K.2
  • 2
    • 0027140986 scopus 로고
    • The striopallidal neuron: a main locus for adenosine-dopamine interactions in the brain
    • Ferré S., et al. The striopallidal neuron: a main locus for adenosine-dopamine interactions in the brain. J. Neurosci. 13 (1993) 5402-5406
    • (1993) J. Neurosci. , vol.13 , pp. 5402-5406
    • Ferré, S.1
  • 3
    • 0027538255 scopus 로고
    • 2 receptor interactions in the striatum as a basis for adenosine/dopamine interactions in the central nervous system
    • 2 receptor interactions in the striatum as a basis for adenosine/dopamine interactions in the central nervous system. Drug Dev. Res. 28 (1993) 374-380
    • (1993) Drug Dev. Res. , vol.28 , pp. 374-380
    • Fuxe, K.1
  • 4
    • 0029666492 scopus 로고    scopus 로고
    • 1 agonists in dopamine-denervated rats
    • 1 agonists in dopamine-denervated rats. Eur. J. Neurosci. 8 (1996) 1176-1181
    • (1996) Eur. J. Neurosci. , vol.8 , pp. 1176-1181
    • Pinna, A.1
  • 5
    • 0030447366 scopus 로고    scopus 로고
    • Synergistic interaction between an adenosine antagonist and a D1 dopamine agonist on rotational behavior and striatal c-Fos induction in 6-hydroxydopamine-lesioned rats
    • Pollack A.E., and Fink J.S. Synergistic interaction between an adenosine antagonist and a D1 dopamine agonist on rotational behavior and striatal c-Fos induction in 6-hydroxydopamine-lesioned rats. Brain Res. 743 (1996) 124-130
    • (1996) Brain Res. , vol.743 , pp. 124-130
    • Pollack, A.E.1    Fink, J.S.2
  • 6
    • 0030615062 scopus 로고    scopus 로고
    • 2A receptor antagonism potentiates l-dopa-induced turning behaviour and c-fos expression in 6-hydroxydopamine-lesioned rats
    • 2A receptor antagonism potentiates l-dopa-induced turning behaviour and c-fos expression in 6-hydroxydopamine-lesioned rats. Eur. J. Pharmacol. 321 (1997) 143-147
    • (1997) Eur. J. Pharmacol. , vol.321 , pp. 143-147
    • Fenu, S.1
  • 7
    • 1842404156 scopus 로고    scopus 로고
    • 1 receptor-mediated effects on c-fos expression
    • 1 receptor-mediated effects on c-fos expression. J. Neurosci. 17 (1997) 8038-8048
    • (1997) J. Neurosci. , vol.17 , pp. 8038-8048
    • Le Moine, C.1
  • 8
    • 0031594271 scopus 로고    scopus 로고
    • 2A antagonist: a novel antiparkinsonian agent that does not provoke dyskinesia in parkinsonian monkeys
    • 2A antagonist: a novel antiparkinsonian agent that does not provoke dyskinesia in parkinsonian monkeys. Ann. Neurol. 43 (1998) 507-513
    • (1998) Ann. Neurol. , vol.43 , pp. 507-513
    • Kanda, T.1
  • 9
    • 0035283648 scopus 로고    scopus 로고
    • 2A receptor antagonist SCH 58261 do not develop tolerance after repeated treatment in 6-hydroxydopamine-lesioned rats
    • 2A receptor antagonist SCH 58261 do not develop tolerance after repeated treatment in 6-hydroxydopamine-lesioned rats. Synapse 39 (2001) 233-238
    • (2001) Synapse , vol.39 , pp. 233-238
    • Pinna, A.1
  • 10
    • 0344052684 scopus 로고    scopus 로고
    • 2A receptor antagonist in MPTP-treated monkeys
    • 2A receptor antagonist in MPTP-treated monkeys. Neurology 52 (1999) 1673-1677
    • (1999) Neurology , vol.52 , pp. 1673-1677
    • Grondin, R.1
  • 11
    • 0042626108 scopus 로고    scopus 로고
    • 2A receptor antagonist treatment of Parkinson's disease
    • 2A receptor antagonist treatment of Parkinson's disease. Neurology 61 (2003) 293-296
    • (2003) Neurology , vol.61 , pp. 293-296
    • Bara-Jimenez, W.1
  • 12
    • 0043126954 scopus 로고    scopus 로고
    • 2A receptor antagonist istradefylline in advanced PD
    • 2A receptor antagonist istradefylline in advanced PD. Neurology 61 (2003) 297-303
    • (2003) Neurology , vol.61 , pp. 297-303
    • Hauser, R.A.1
  • 13
    • 14544288232 scopus 로고    scopus 로고
    • 2A receptor antagonists in Parkinson's disease
    • 2A receptor antagonists in Parkinson's disease. Pharmacol. Ther. 105 (2005) 267-310
    • (2005) Pharmacol. Ther. , vol.105 , pp. 267-310
    • Xu, K.1
  • 14
    • 0034970280 scopus 로고    scopus 로고
    • 2A adenosine receptor antagonist, counteracts parkinsonian-like muscle rigidity in rats
    • 2A adenosine receptor antagonist, counteracts parkinsonian-like muscle rigidity in rats. Synapse 41 (2001) 160-171
    • (2001) Synapse , vol.41 , pp. 160-171
    • Wardas, J.1
  • 15
    • 0346365547 scopus 로고    scopus 로고
    • 2A antagonist KF17837 reverses the locomotor suppression and tremulous jaw movements induced by haloperidol in rats: possible relevance to parkinsonism
    • 2A antagonist KF17837 reverses the locomotor suppression and tremulous jaw movements induced by haloperidol in rats: possible relevance to parkinsonism. Behav. Brain Res. 148 (2004) 47-54
    • (2004) Behav. Brain Res. , vol.148 , pp. 47-54
    • Correa, M.1
  • 16
    • 3543107307 scopus 로고    scopus 로고
    • 2A receptors antagonizes parkinsonian tremor in the rat tacrine model by an action on specific striatal regions
    • 2A receptors antagonizes parkinsonian tremor in the rat tacrine model by an action on specific striatal regions. Exp. Neurol. 189 (2004) 182-188
    • (2004) Exp. Neurol. , vol.189 , pp. 182-188
    • Simola, N.1
  • 17
    • 0026326607 scopus 로고
    • The striatal restricted adenosine A2 receptor (RDC8) is expressed by enkephalin but not by substance P neurons. An in situ hybridization histochemistry study
    • Schiffmann S.N., et al. The striatal restricted adenosine A2 receptor (RDC8) is expressed by enkephalin but not by substance P neurons. An in situ hybridization histochemistry study. J. Neurochem. 57 (1991) 1062-1067
    • (1991) J. Neurochem. , vol.57 , pp. 1062-1067
    • Schiffmann, S.N.1
  • 18
    • 0026763441 scopus 로고
    • Molecular cloning of the rat A2 adenosine receptor: selective co-expression with D2 dopamine receptors in rat striatum
    • Fink J.S., et al. Molecular cloning of the rat A2 adenosine receptor: selective co-expression with D2 dopamine receptors in rat striatum. Mol. Brain Res. 14 (1992) 186-195
    • (1992) Mol. Brain Res. , vol.14 , pp. 186-195
    • Fink, J.S.1
  • 19
    • 0029029844 scopus 로고
    • Adenosine antagonists potentiate D2 dopamine-dependent activation of Fos in the striatopallidal pathway
    • Pollack A.E., and Fink J.S. Adenosine antagonists potentiate D2 dopamine-dependent activation of Fos in the striatopallidal pathway. Neuroscience 68 (1995) 721-728
    • (1995) Neuroscience , vol.68 , pp. 721-728
    • Pollack, A.E.1    Fink, J.S.2
  • 20
    • 0034618819 scopus 로고    scopus 로고
    • 2A receptor antagonist reverses increased GABA release in the globus pallidus of unilateral 6-hydroxydopamine-lesioned rats: a microdialysis study
    • 2A receptor antagonist reverses increased GABA release in the globus pallidus of unilateral 6-hydroxydopamine-lesioned rats: a microdialysis study. Neuroscience 100 (2000) 53-62
    • (2000) Neuroscience , vol.100 , pp. 53-62
    • Ochi, M.1
  • 21
    • 13844315635 scopus 로고    scopus 로고
    • Actions of adenosine at its receptors in the CNS: insights from knockouts and drugs
    • Fredholm B.B., et al. Actions of adenosine at its receptors in the CNS: insights from knockouts and drugs. Annu. Rev. Pharmacol. Toxicol. 45 (2005) 385-412
    • (2005) Annu. Rev. Pharmacol. Toxicol. , vol.45 , pp. 385-412
    • Fredholm, B.B.1
  • 22
    • 0034738134 scopus 로고    scopus 로고
    • Association of coffee and caffeine intake with the risk of Parkinson disease
    • Ross G.W., et al. Association of coffee and caffeine intake with the risk of Parkinson disease. JAMA 283 (2000) 2674-2679
    • (2000) JAMA , vol.283 , pp. 2674-2679
    • Ross, G.W.1
  • 23
    • 0034950069 scopus 로고    scopus 로고
    • Prospective study of caffeine consumption and risk of Parkinson's disease in men and women
    • Ascherio A., et al. Prospective study of caffeine consumption and risk of Parkinson's disease in men and women. Ann. Neurol. 50 (2001) 56-63
    • (2001) Ann. Neurol. , vol.50 , pp. 56-63
    • Ascherio, A.1
  • 24
    • 0037432281 scopus 로고    scopus 로고
    • Caffeine, postmenopausal estrogen, and risk of Parkinson's disease
    • Ascherio A., et al. Caffeine, postmenopausal estrogen, and risk of Parkinson's disease. Neurology 60 (2003) 790-795
    • (2003) Neurology , vol.60 , pp. 790-795
    • Ascherio, A.1
  • 25
    • 0035874345 scopus 로고    scopus 로고
    • 2A adenosine receptor inactivation in a model of Parkinson's disease
    • 2A adenosine receptor inactivation in a model of Parkinson's disease. J. Neurosci. 21 (2001) RC143
    • (2001) J. Neurosci. , vol.21
    • Chen, J.-F.1
  • 26
    • 0036020950 scopus 로고    scopus 로고
    • 2A receptor blockade in experimental models of Parkinson's disease
    • 2A receptor blockade in experimental models of Parkinson's disease. J. Neurochem. 80 (2002) 262-270
    • (2002) J. Neurochem. , vol.80 , pp. 262-270
    • Ikeda, K.1
  • 27
    • 0037192439 scopus 로고    scopus 로고
    • Caffeine's neuroprotection against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity shows no tolerance to chronic caffeine administration in mice
    • Xu K., et al. Caffeine's neuroprotection against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity shows no tolerance to chronic caffeine administration in mice. Neurosci. Lett. 322 (2002) 13-16
    • (2002) Neurosci. Lett. , vol.322 , pp. 13-16
    • Xu, K.1
  • 28
    • 32544436383 scopus 로고    scopus 로고
    • Estrogen prevents neuroprotection by caffeine in the mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease
    • Xu K., et al. Estrogen prevents neuroprotection by caffeine in the mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease. J. Neurosci. 26 (2006) 535-541
    • (2006) J. Neurosci. , vol.26 , pp. 535-541
    • Xu, K.1
  • 29
    • 0029417320 scopus 로고
    • 2a adenosine receptor antagonists on cerebral ischemic injury in the gerbil
    • 2a adenosine receptor antagonists on cerebral ischemic injury in the gerbil. Brain Res. 705 (1995) 79-84
    • (1995) Brain Res. , vol.705 , pp. 79-84
    • Phillis, J.W.1
  • 30
    • 0032479984 scopus 로고    scopus 로고
    • 2A receptor antagonist
    • 2A receptor antagonist. Brain Res. 800 (1998) 328-335
    • (1998) Brain Res. , vol.800 , pp. 328-335
    • Jones, P.A.1
  • 31
    • 0032217044 scopus 로고    scopus 로고
    • 2A receptors by SCH 58261 results in neuroprotective effects in cerebral ischaemia in rats
    • 2A receptors by SCH 58261 results in neuroprotective effects in cerebral ischaemia in rats. Neuroreport 9 (1998) 3955-3959
    • (1998) Neuroreport , vol.9 , pp. 3955-3959
    • Monopoli, A.1
  • 32
    • 0038113064 scopus 로고    scopus 로고
    • 2A antagonists
    • 2A antagonists. J. Neurosci. 23 (2003) 5361-5369
    • (2003) J. Neurosci. , vol.23 , pp. 5361-5369
    • Blum, D.1
  • 33
    • 0942298557 scopus 로고    scopus 로고
    • 2A receptor attenuates 3-nitropropionic acid-induced striatal damage
    • 2A receptor attenuates 3-nitropropionic acid-induced striatal damage. J. Neurochem. 88 (2004) 538-544
    • (2004) J. Neurochem. , vol.88 , pp. 538-544
    • Fink, J.S.1
  • 34
    • 0345060347 scopus 로고    scopus 로고
    • Adenosinergic protection of dopaminergic and GABAergic neurons against mitochondrial inhibition through receptors located in the substantia nigra and striatum, respectively
    • Alfinito P.D., et al. Adenosinergic protection of dopaminergic and GABAergic neurons against mitochondrial inhibition through receptors located in the substantia nigra and striatum, respectively. J. Neurosci. 23 (2003) 10982-10987
    • (2003) J. Neurosci. , vol.23 , pp. 10982-10987
    • Alfinito, P.D.1
  • 35
    • 0038415954 scopus 로고    scopus 로고
    • 2A receptor blockade of β-amyloid neurotoxicity
    • 2A receptor blockade of β-amyloid neurotoxicity. Br. J. Pharmacol. 138 (2003) 1207-1209
    • (2003) Br. J. Pharmacol. , vol.138 , pp. 1207-1209
    • Dall'Igna, O.P.1
  • 36
    • 0034923094 scopus 로고    scopus 로고
    • The role and regulation of adenosine in the central nervous system
    • Dunwiddie T.V., and Masino S.A. The role and regulation of adenosine in the central nervous system. Annu. Rev. Neurosci. 24 (2001) 31-55
    • (2001) Annu. Rev. Neurosci. , vol.24 , pp. 31-55
    • Dunwiddie, T.V.1    Masino, S.A.2
  • 37
    • 0035830550 scopus 로고    scopus 로고
    • 2A adenosine receptors
    • 2A adenosine receptors. Life Sci. 68 (2001) 1343-1350
    • (2001) Life Sci. , vol.68 , pp. 1343-1350
    • Li, X.X.1
  • 38
    • 0036016115 scopus 로고    scopus 로고
    • 2A receptor activation on the evoked release of glutamate from rat cerebrocortical synaptosomes
    • 2A receptor activation on the evoked release of glutamate from rat cerebrocortical synaptosomes. Br. J. Pharmacol. 136 (2002) 434-440
    • (2002) Br. J. Pharmacol. , vol.136 , pp. 434-440
    • Marchi, M.1
  • 39
    • 0030268068 scopus 로고    scopus 로고
    • 2A-receptors
    • 2A-receptors. Glia 18 (1996) 152-160
    • (1996) Glia , vol.18 , pp. 152-160
    • Fiebich, B.L.1
  • 40
    • 7044247188 scopus 로고    scopus 로고
    • 2A receptors in bone marrow cells reveals their significant contribution to the development of ischemic brain injury
    • 2A receptors in bone marrow cells reveals their significant contribution to the development of ischemic brain injury. Nat. Med. 10 (2004) 1081-1087
    • (2004) Nat. Med. , vol.10 , pp. 1081-1087
    • Yu, L.1
  • 41
    • 14544287564 scopus 로고    scopus 로고
    • KW-6002 protects from MPTP induced dopaminergic toxicity in the mouse
    • Pierri M., et al. KW-6002 protects from MPTP induced dopaminergic toxicity in the mouse. Neuropharmacology 48 (2005) 517-524
    • (2005) Neuropharmacology , vol.48 , pp. 517-524
    • Pierri, M.1
  • 42
    • 0036470494 scopus 로고    scopus 로고
    • 2A adenosine receptors
    • 2A adenosine receptors. J. Neurosci. 22 (2002) 1054-1062
    • (2002) J. Neurosci. , vol.22 , pp. 1054-1062
    • Fredduzzi, S.1
  • 43
    • 0042141599 scopus 로고    scopus 로고
    • 2A antagonist prevents dopamine agonist-induced motor complications in animal models of Parkinson's disease
    • 2A antagonist prevents dopamine agonist-induced motor complications in animal models of Parkinson's disease. Exp. Neurol. 184 (2003) 285-294
    • (2003) Exp. Neurol. , vol.184 , pp. 285-294
    • Bibbiani, F.1
  • 44
    • 0037345646 scopus 로고    scopus 로고
    • 2a receptor antagonist KW-6002 in a rat model of l-DOPA-induced dyskinesia
    • 2a receptor antagonist KW-6002 in a rat model of l-DOPA-induced dyskinesia. J. Neurochem. 84 (2003) 1398-1410
    • (2003) J. Neurochem. , vol.84 , pp. 1398-1410
    • Lundblad, M.1
  • 45
    • 33646547603 scopus 로고    scopus 로고
    • Expression of dyskinetic movements and turning behaviour in subchronic l-DOPA 6-hydroxydopamine-treated rats is influenced by the testing environment
    • Pinna A., et al. Expression of dyskinetic movements and turning behaviour in subchronic l-DOPA 6-hydroxydopamine-treated rats is influenced by the testing environment. Behav. Brain Res. 171 (2006) 175-178
    • (2006) Behav. Brain Res. , vol.171 , pp. 175-178
    • Pinna, A.1
  • 46
    • 0031925945 scopus 로고    scopus 로고
    • l-DOPA-induced dyskinesia in the rat is associated with striatal overexpression of prodynorphin- and glutamic acid decarboxylase mRNA
    • Cenci M.A., et al. l-DOPA-induced dyskinesia in the rat is associated with striatal overexpression of prodynorphin- and glutamic acid decarboxylase mRNA. Eur. J. Neurosci. 10 (1998) 2694-2706
    • (1998) Eur. J. Neurosci. , vol.10 , pp. 2694-2706
    • Cenci, M.A.1
  • 47
    • 0842299499 scopus 로고    scopus 로고
    • 2A receptors plus l-DOPA after nigrostriatal lesion results in GAD67 mRNA changes different from l-DOPA alone in the rat globus pallidus and substantia nigra reticulata
    • 2A receptors plus l-DOPA after nigrostriatal lesion results in GAD67 mRNA changes different from l-DOPA alone in the rat globus pallidus and substantia nigra reticulata. Exp. Neurol. 184 (2003) 679-687
    • (2003) Exp. Neurol. , vol.184 , pp. 679-687
    • Carta, A.1
  • 48
    • 0344738704 scopus 로고    scopus 로고
    • 2A and dopamine receptor interactions in basal ganglia of dopamine denervated rats
    • 2A and dopamine receptor interactions in basal ganglia of dopamine denervated rats. Neurology 61 Suppl. 6 (2003) S39-S43
    • (2003) Neurology , vol.61 , Issue.SUPPL. 6
    • Carta, A.1
  • 49
    • 0642345900 scopus 로고    scopus 로고
    • Striatal glutamatergic mechanisms and extrapyramidal movement disorders
    • Chase T.N., et al. Striatal glutamatergic mechanisms and extrapyramidal movement disorders. Neurotox. Res. 5 (2003) 139-146
    • (2003) Neurotox. Res. , vol.5 , pp. 139-146
    • Chase, T.N.1
  • 50
  • 52
    • 10744224952 scopus 로고    scopus 로고
    • 2A receptor signaling: relevance for striatal function and Parkinson's disease
    • 2A receptor signaling: relevance for striatal function and Parkinson's disease. Neurology 61 Suppl. 6 (2003) S19-S23
    • (2003) Neurology , vol.61 , Issue.SUPPL. 6
    • Fuxe, K.1
  • 53
    • 22944490592 scopus 로고    scopus 로고
    • Receptor-receptor interactions, receptor mosaics, and basic principles of molecular network organization: possible implications for drug development
    • Agnati L.F., et al. Receptor-receptor interactions, receptor mosaics, and basic principles of molecular network organization: possible implications for drug development. J. Mol. Neurosci. 26 (2005) 193-208
    • (2005) J. Mol. Neurosci. , vol.26 , pp. 193-208
    • Agnati, L.F.1
  • 54
    • 25844477182 scopus 로고    scopus 로고
    • 2 heteromeric receptor complexes and their function
    • 2 heteromeric receptor complexes and their function. J. Mol. Neurosci. 26 (2005) 209-220
    • (2005) J. Mol. Neurosci. , vol.26 , pp. 209-220
    • Fuxe, K.1
  • 55
    • 0037124032 scopus 로고    scopus 로고
    • 2A receptors and dopamine D2 receptors
    • 2A receptors and dopamine D2 receptors. J. Biol. Chem. 277 (2002) 18091-18097
    • (2002) J. Biol. Chem. , vol.277 , pp. 18091-18097
    • Hillion, J.1
  • 56
    • 0344875553 scopus 로고    scopus 로고
    • 2 receptor-receptor heteromerization: qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer
    • 2 receptor-receptor heteromerization: qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer. J. Biol. Chem. 278 (2003) 46741-46749
    • (2003) J. Biol. Chem. , vol.278 , pp. 46741-46749
    • Canals, M.1
  • 57
    • 0942265965 scopus 로고    scopus 로고
    • 2A receptors: qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer
    • 2A receptors: qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer. J. Neurochem. 88 (2004) 726-734
    • (2004) J. Neurochem. , vol.88 , pp. 726-734
    • Canals, M.1
  • 59
    • 0034255509 scopus 로고    scopus 로고
    • 2A receptor antagonist
    • 2A receptor antagonist. J. Neurosci. 20 (2000) 5848-5852
    • (2000) J. Neurosci. , vol.20 , pp. 5848-5852
    • Aoyama, S.1
  • 61
    • 13444271067 scopus 로고    scopus 로고
    • 3 heteromeric complexes
    • 3 heteromeric complexes. Mol. Pharmacol. 67 (2005) 400-407
    • (2005) Mol. Pharmacol. , vol.67 , pp. 400-407
    • Torvinen, M.1
  • 62
    • 0030613635 scopus 로고    scopus 로고
    • Expression of dopamine D3 receptor dimers and tetramers in brain and in transfected cells
    • Nimchinsky E.A., et al. Expression of dopamine D3 receptor dimers and tetramers in brain and in transfected cells. J. Biol. Chem. 272 (1997) 29229-29237
    • (1997) J. Biol. Chem. , vol.272 , pp. 29229-29237
    • Nimchinsky, E.A.1
  • 63
    • 0032587703 scopus 로고    scopus 로고
    • 2A and group I metabotropic glutamate receptors synergistically modulate the binding characteristics of dopamine D2 receptors in the rat striatum
    • 2A and group I metabotropic glutamate receptors synergistically modulate the binding characteristics of dopamine D2 receptors in the rat striatum. Neuropharmacology 38 (1999) 129-140
    • (1999) Neuropharmacology , vol.38 , pp. 129-140
    • Ferré, S.1
  • 65
    • 0037015027 scopus 로고    scopus 로고
    • 5 receptors: implications for striatal neuronal function
    • 5 receptors: implications for striatal neuronal function. Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 11940-11945
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 11940-11945
    • Ferré, S.1
  • 66
    • 13244264871 scopus 로고    scopus 로고
    • 2A and metabotropic group 5 receptors in glutamatergic nerve terminals of the rat striatum
    • 2A and metabotropic group 5 receptors in glutamatergic nerve terminals of the rat striatum. J. Neurochem. 92 (2005) 433-441
    • (2005) J. Neurochem. , vol.92 , pp. 433-441
    • Rodrigues, R.J.1
  • 69
    • 3242765264 scopus 로고    scopus 로고
    • 5 receptors increase their efficacy in reversing Parkinsonian deficits in rats
    • 5 receptors increase their efficacy in reversing Parkinsonian deficits in rats. Neuropsychopharmacology 29 (2004) 1451-1461
    • (2004) Neuropsychopharmacology , vol.29 , pp. 1451-1461
    • Coccurello, R.1
  • 70
    • 27744450594 scopus 로고    scopus 로고
    • 2A receptors in normal and parkinsonian mice
    • 2A receptors in normal and parkinsonian mice. J. Neurosci. 25 (2005) 10414-10419
    • (2005) J. Neurosci. , vol.25 , pp. 10414-10419
    • Kachroo, A.1
  • 71
    • 0042467972 scopus 로고    scopus 로고
    • Molecular mechanisms and therapeutical implications of intramembrane receptor/receptor interactions among heptahelical receptors with examples from the striatopallidal GABA neurons
    • Agnati L.F., et al. Molecular mechanisms and therapeutical implications of intramembrane receptor/receptor interactions among heptahelical receptors with examples from the striatopallidal GABA neurons. Pharmacol. Rev. 55 (2003) 509-550
    • (2003) Pharmacol. Rev. , vol.55 , pp. 509-550
    • Agnati, L.F.1
  • 72
    • 33644551294 scopus 로고    scopus 로고
    • Presynaptic control of striatal glutamatergic neurotransmission by adenosine A1-A2A receptor heteromers
    • Ciruela F., et al. Presynaptic control of striatal glutamatergic neurotransmission by adenosine A1-A2A receptor heteromers. J. Neurosci. 26 (2006) 2080-2087
    • (2006) J. Neurosci. , vol.26 , pp. 2080-2087
    • Ciruela, F.1
  • 74
    • 0033724826 scopus 로고    scopus 로고
    • Pathophysiology of the basal ganglia in Parkinson's disease
    • Obeso J.A., et al. Pathophysiology of the basal ganglia in Parkinson's disease. Trends Neurosci. 23 (2000) S8-S19
    • (2000) Trends Neurosci. , vol.23
    • Obeso, J.A.1
  • 75
    • 0029670648 scopus 로고    scopus 로고
    • 2a receptors in regulating GABAergic synaptic transmission in striatal medium spiny neurons
    • 2a receptors in regulating GABAergic synaptic transmission in striatal medium spiny neurons. J. Neurosci. 16 (1996) 605-611
    • (1996) J. Neurosci. , vol.16 , pp. 605-611
    • Mori, A.1


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