Role of DptE and DptF in the lipidation reaction of daptomycin

FEBS Journal

Volumn 275, Issue 21, 2008, Pages 5343-5354

  Wittmann, Melanie ^a   Linne, Uwe ^a   Pohlmann, Verena ^a   Marahiel, Mohamed A ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Acidic lipopeptide antibiotics; AMP ligase; Daptomycin; Lipidation reaction; Nonribosomal peptide synthetases

Indexed keywords

A 54145; ACYL CARRIER PROTEIN; ADENOSINE TRIPHOSPHATE; ANTIBIOTIC AGENT; DAPTOMYCIN; FATTY ACID; LIPOPEPTIDE; LONG CHAIN FATTY ACID; PEPTIDE SYNTHASE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL ANALYSIS; CHEMICAL REACTION KINETICS; DPTE GENE; DPTF GENE; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME ANALYSIS; ENZYME PURIFICATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE; FATTY ACID SYNTHESIS; FATTY ACID TRANSPORT; GENE; GENE ACTIVATION; GENE EXPRESSION; GENE FUNCTION; HETEROLOGOUS EXPRESSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIPID PEROXIDATION; LIPIDATION REACTION; LIPOGENESIS; MOLECULAR CLONING; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN ENGINEERING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; STEADY STATE;

ACYL CARRIER PROTEIN; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; CARBON-SULFUR LIGASES; DAPTOMYCIN; FATTY ACIDS; LIPOPEPTIDES; PEPTIDE SYNTHASES; STREPTOMYCES;

POSIBACTERIA; STREPTOMYCES FILAMENTOSUS;

EID: 53849091701     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2008.06664.x     Document Type: Article

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