Promiscuous fatty acyl CoA ligases produce acyl-CoA and acyl-SNAC precursors for polyketide biosynthesis

Journal of the American Chemical Society

Volumn 127, Issue 26, 2005, Pages 9388-9389

  Arora, Pooja ^a   Vats, Archana ^a   Saxena, Priti ^a   Mohanty, Debasisa ^a   Gokhale, Rajesh S ^a  

^a NATIONAL INSTITUTE OF IMMUNOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL COENZYME A; CARBON 14; FADD15 PROTEIN; FADD19 PROTEIN; FADD6 PROTEIN; FATTY ACID; LAURIC ACID; LONG CHAIN FATTY ACID COENZYME A LIGASE; POLYKETIDE; UNCLASSIFIED DRUG;

ARTICLE; BIOSYNTHESIS; CELL FREE SYSTEM; CHEMICAL STRUCTURE; ENZYME ASSAY; ENZYME SUBSTRATE; ESCHERICHIA COLI; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ACETYL COENZYME A; ACYL COENZYME A; CAPRYLATES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COENZYME A LIGASES; FATTY ACIDS; MOLECULAR STRUCTURE; TIME FACTORS;

EID: 21644469444     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja052991s     Document Type: Article

References (28)

1. (a) Zirkle, R.; Ligon, J. M.; Molnar, I. Microbiology 2004, 150, 2761-2774.
2. (b) Kalaitzis, J. A.; Moore, B. S. J. Nat. Prod. 2004, 67, 1419-1422.
3. (c) Watanabe, K.; Rude, M. A.; Walsh, C. T.; Khosla, C. Proc. Natl. Acad. Sci. U.S.A. 2003, 100, 9774-9778.
4. (d) Ichinose, K.; Ozawa, M.; Itou, K.; Kunieda, K.; Ebizuka, Y. Microbiology 2003, 149, 1633-1645.
5. (e) Eppelmann, K.; Doekel, S.; Marahiel, M. A. J. Biol. Chem. 2001, 276, 34824-34831.
6. (a) Rodriquez, E.; Hu, Z.; Ou, S.; Volchegursky, Y.; Hutchinson, C. R.; McDaniel, R. J. Ind. Microbiol. Biotechnol. 2003, 30, 480-488.
7. (b) Pfeifer, B. A.; Khosla, C. Microbiol. Mol. Biol. Rev. 2001, 65, 106-118.
8. (c) Hopwood, D. A. Chem. Rev. 1997, 97, 2465-2498.
9. (a) Murli, S.; Kennedy, J.; Dayem, L. C.; Carney, J. R.; Kealey, J. T. J. Ind. Microbiol. Biotechnol. 2003, 30, 500-509.
10. (b) Pfeifer, B. A.; Admiraal, S. J.; Gramajo, H.; Cane, D. E.; Khosla, C. Science 2001, 291, 1790-1792.
11. (c) Lombo, F.; Pfeifer, B.; Leaf, T.; Ou, S.; Kim, Y. S.; Cane, D. E.; Licari, P.; Khosla, C. Biotechnol. Prog. 2001, 17, 612-617.
12. (a) Koumoutsi, A.; Chen, X. H.; Henne, A.; Liesegang, H.; Hitzeroth, G.; Franke, P.; Vater, J.; Borriss, R. J. Bacteriol. 2004, 186, 1084-1096.
13. (b) Tsuge, K.; Akiyama, T.; Shoda, M. J. Bacteriol. 2001, 183, 6265-6273.
14. (c) Du, L.; Sanchez, C.; Chen, M.; Edwards, D. J.; Shen. B. Chem. Biol. 2000, 7, 623-642.
15. (d) Duitman, E. H.; Hamoen, L. W.; Rembold, M.; Venema, G.; Seitz, H.; Saenger, W.; Bernhard, F.; Reinhardt, R.; Schmidt, M.; Ullrich, C.; Stein, T.; Leenders, F.; Vater, J. Proc. Natl. Acad. Sci. U.S.A. 1999, 96, 13294-13299.
16. Cole, S. T. et al. Nature 1998, 393, 537-544.
17. Trivedi, O. A.; Arora, P.; Sridharan, V.; Tickoo, R.; Mohanty, D.; Gokhale, R. S. Nature 2004, 428, 441-445.
18. Pei, Z.; Oey, N. A.; Zuidervaart, M. M.; Jia, Z.; Li, Y.; Steinberg, S. J.; Smith, K. D.; Watkins, P. A. J. Biol. Chem. 2003, 278, 47070-8.
19. (a) Vanhove, G.; Van Veldhoven, P. P.; Vanhoutte, F.; Parmentier, G.; Eyssen H. J.; Mannaerts, G. P. J Biol Chem. 1991, 266, 24670-5.
20. (b) Foulon, V.; Asselberghs, S.; Geens, W.; Mannaerts, G. P.; Casteels, M.; Van Veldhoven, P. P. J. Lipid Res. 2003, 44, 2349-55.
21. (a) Saxena, P.; Yadav, G.; Mohanty, D.; Gokhale, R. S. J. Biol. Chem. 2003, 278, 44780-44790.
22. (b) Sankaranarayanan, R.; Saxena, P.; Marathe, U. B.; Gokhale, R. S.; Shanmugam, V. M.; Rukmini, R. Nat. Struct. Mol. Biol. 2004, 11, 894-900.
23. Trivedi, O. A.; Arora, P.; Vats, A.; Ansari, M. Z.; Tickoo, R.; Sridharan, V.; Mohanty, D.; Gokhale, R. S. Mol. Cell. 2005, 17, 631-43.
24. (a) Ehmann, D. E.; Trauger, J. W.; Stachelhaus, T.; Walsh, C. T. Chem. Biol. 2000, 7, 765-772.
25. (b) Jacobsen, J. R.; Hutchinson, C. R.; Cane, D. E.; Khosla, C. Science 1997, 277, 367-369.
26. (c) Cane, D. E.; Yang, C. C. J. Am. Chem. Soc. 1987, 109, 1255-1257.
27. (d) Yue, S.; Duncan, J. S.; Yamamoto, Y.; Hutchison, C. R. J. Am. Chem. Soc. 1987, 109, 1253-1254.
28. Oguro, S.; Akashi, T.; Ayabe, S.; Nosuchi, H.; Abe, I. Biochem Biophys Res Commun 2004, 325, 561-567.