Simulations of a G protein-coupled receptor homology model predict dynamic features and a ligand binding site

FEBS Letters

Volumn 582, Issue 23-24, 2008, Pages 3335-3342

  Wolf, Steffen ^a   Böckmann, Marcus ^a   Höweler, Udo ^b   Schlitter, Jürgen ^a   Gerwert, Klaus ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b CHEOPS Molecular Modelling   (Germany)

Author keywords

Beta(2) adrenoreceptor; Epinephrine; GPCR; Homology model; Ligand binding; Molecular dynamics simulation

Indexed keywords

ADRENALIN; BETA 2 ADRENERGIC RECEPTOR; G PROTEIN COUPLED RECEPTOR; RHODOPSIN;

ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; LIGAND BINDING; MOLECULAR DYNAMICS; NUCLEOTIDE SEQUENCE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN STRUCTURE; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; SIMULATION;

AMINO ACID SEQUENCE; BINDING SITES; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; EPINEPHRINE; LIGANDS; MODELS, MOLECULAR; POINT MUTATION; RECEPTORS, ADRENERGIC, BETA-2; RHODOPSIN; STRUCTURAL HOMOLOGY, PROTEIN;

EID: 53349103176     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2008.08.022     Document Type: Article

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