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Volumn 255, Issue 1, 2008, Pages 119-128

A simple reaction kinetic model of rapid (G protein dependent) and slow (β-Arrestin dependent) transmission

Author keywords

G protein signaling; MAPK ERK; Reaction kinetic systems; Regulators of G protein signaling; Slow transmission

Indexed keywords

BETA ARRESTIN; GUANINE NUCLEOTIDE BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE;

EID: 53149100446     PISSN: 00225193     EISSN: 10958541     Source Type: Journal    
DOI: 10.1016/j.jtbi.2008.07.032     Document Type: Article
Times cited : (5)

References (45)
  • 1
    • 0032555422 scopus 로고    scopus 로고
    • A mathematical model for ligand/receptor/G-protein dynamics and acrin polymerization in human neutrophils
    • Adams J.A., Omann G.M., and Linderman J.J. A mathematical model for ligand/receptor/G-protein dynamics and acrin polymerization in human neutrophils. J. Theor. Biol. 193 (1998) 543-560
    • (1998) J. Theor. Biol. , vol.193 , pp. 543-560
    • Adams, J.A.1    Omann, G.M.2    Linderman, J.J.3
  • 2
    • 33646271819 scopus 로고    scopus 로고
    • Computational neuropharmacology: dynamical approaches in drug discovery
    • Aradi I., and Érdi P. Computational neuropharmacology: dynamical approaches in drug discovery. Trends Pharmacol. Sci. 27 (2006) 240-243
    • (2006) Trends Pharmacol. Sci. , vol.27 , pp. 240-243
    • Aradi, I.1    Érdi, P.2
  • 4
    • 22744449073 scopus 로고    scopus 로고
    • An Akt/β-Arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior
    • Beaulieu J.M., Sotinkova T.D., Marion S., Lefkowitz R.J., Gainetdinov R.R., and Caron M.G. An Akt/β-Arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior. Cell 122 (2005) 261-273
    • (2005) Cell , vol.122 , pp. 261-273
    • Beaulieu, J.M.1    Sotinkova, T.D.2    Marion, S.3    Lefkowitz, R.J.4    Gainetdinov, R.R.5    Caron, M.G.6
  • 6
    • 0035721572 scopus 로고    scopus 로고
    • Dopamine as a prolactin (PRL) inhibitor
    • Ben-Jonathan N., and Hnasko R. Dopamine as a prolactin (PRL) inhibitor. Endocr. Rev. 22 (2001) 724-763
    • (2001) Endocr. Rev. , vol.22 , pp. 724-763
    • Ben-Jonathan, N.1    Hnasko, R.2
  • 7
    • 0037047611 scopus 로고    scopus 로고
    • MAP kinase phosphatase as a locus of flexibility in a mitogen-activated protein kinase signaling network
    • Bhalla U.S., Ram P.T., and Iyengar R. MAP kinase phosphatase as a locus of flexibility in a mitogen-activated protein kinase signaling network. Science 297 (2002) 1018-1023
    • (2002) Science , vol.297 , pp. 1018-1023
    • Bhalla, U.S.1    Ram, P.T.2    Iyengar, R.3
  • 8
    • 0042428926 scopus 로고    scopus 로고
    • Modelling of signalling via g-protein coupled receptors: pathway-dependent agonist potency and efficacy
    • Chen C.Y., Cordeaux Y., and Hill S.J. Modelling of signalling via g-protein coupled receptors: pathway-dependent agonist potency and efficacy. Bull. Math. Biol. 65 (2003) 933-958
    • (2003) Bull. Math. Biol. , vol.65 , pp. 933-958
    • Chen, C.Y.1    Cordeaux, Y.2    Hill, S.J.3
  • 9
    • 33745027709 scopus 로고    scopus 로고
    • Multiple equilibria in complex chemical reaction networks: II. The species-reaction graph
    • Craciun G., and Feinberg M. Multiple equilibria in complex chemical reaction networks: II. The species-reaction graph. SIAM J. Appl. Math. 66 (2006) 1321-1338
    • (2006) SIAM J. Appl. Math. , vol.66 , pp. 1321-1338
    • Craciun, G.1    Feinberg, M.2
  • 10
    • 33744744785 scopus 로고    scopus 로고
    • Understanding bistability in complex enzyme-driven reaction networks
    • Craciun G., and Feinberg M. Understanding bistability in complex enzyme-driven reaction networks. Proc. Natl. Acad. Sci. USA 103 (2006) 8697-8702
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 8697-8702
    • Craciun, G.1    Feinberg, M.2
  • 11
    • 0034718604 scopus 로고    scopus 로고
    • The proliferative and antiapoptotic effects of substance P are facilitated by formation of a beta-arrestin-dependent scaffolding complex
    • DeFea K.A., Vaughn Z.D., O'Bryan E.M., Nishijima D., Dery O., and Bunett N.W. The proliferative and antiapoptotic effects of substance P are facilitated by formation of a beta-arrestin-dependent scaffolding complex. Proc. Natl. Acad. Sci. USA 98 (2000) 11086-11091
    • (2000) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 11086-11091
    • DeFea, K.A.1    Vaughn, Z.D.2    O'Bryan, E.M.3    Nishijima, D.4    Dery, O.5    Bunett, N.W.6
  • 14
    • 0009377452 scopus 로고    scopus 로고
    • On chemical kinetics of a certain class
    • Feinberg M. On chemical kinetics of a certain class. Arch. Ration. Mech. Anal. 46 (2004) 1-41
    • (2004) Arch. Ration. Mech. Anal. , vol.46 , pp. 1-41
    • Feinberg, M.1
  • 15
    • 0029719789 scopus 로고    scopus 로고
    • Desensitization of G protein-coupled receptors
    • Freedman N.J., and Lefkowitz R.J. Desensitization of G protein-coupled receptors. Recent Prog. Horm. Res. 51 (1996) 319-351
    • (1996) Recent Prog. Horm. Res. , vol.51 , pp. 319-351
    • Freedman, N.J.1    Lefkowitz, R.J.2
  • 16
    • 0033771336 scopus 로고    scopus 로고
    • Prolactin: structure, function and regulation of secretion
    • Freeman M.E., Kanyicska B., Lerant A., and Nagy G. Prolactin: structure, function and regulation of secretion. Physiol. Rev. 80 (2000) 1523-1631
    • (2000) Physiol. Rev. , vol.80 , pp. 1523-1631
    • Freeman, M.E.1    Kanyicska, B.2    Lerant, A.3    Nagy, G.4
  • 17
    • 34447642715 scopus 로고    scopus 로고
    • The evasive nature of drug efficacy: implications for drug discovery
    • Galandrin S., Oligny-Longpre G., and Bouvier M. The evasive nature of drug efficacy: implications for drug discovery. Trends Pharmacol. Sci. 28 (2007) 423-430
    • (2007) Trends Pharmacol. Sci. , vol.28 , pp. 423-430
    • Galandrin, S.1    Oligny-Longpre, G.2    Bouvier, M.3
  • 18
    • 17344362824 scopus 로고    scopus 로고
    • Cell growth control by G protein-coupled receptors: from signal transduction to signal integration
    • Gutkind J.S. Cell growth control by G protein-coupled receptors: from signal transduction to signal integration. Oncogene 17 (1998) 1331-1342
    • (1998) Oncogene , vol.17 , pp. 1331-1342
    • Gutkind, J.S.1
  • 19
    • 0031893949 scopus 로고    scopus 로고
    • The pathways connecting G protein-coupled receptors to the nucleus through divergent mitogen-activated protein kinase cascades
    • Gutkind J.S. The pathways connecting G protein-coupled receptors to the nucleus through divergent mitogen-activated protein kinase cascades. J. Biol. Chem. 273 (1998) 1839-1842
    • (1998) J. Biol. Chem. , vol.273 , pp. 1839-1842
    • Gutkind, J.S.1
  • 21
    • 0029790351 scopus 로고    scopus 로고
    • Ultrasensitivity in the mitogen-activated protein kinase cascade
    • Huang C.Y.F., and Ferrell Jr. J.E. Ultrasensitivity in the mitogen-activated protein kinase cascade. Proc. Natl. Acad. Sci. USA 93 (1996) 10078
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 10078
    • Huang, C.Y.F.1    Ferrell Jr., J.E.2
  • 22
    • 0242384221 scopus 로고    scopus 로고
    • Physiological actions of regulators of G-protein signaling (RGS) proteins
    • Ishii M., and Kurachi Y. Physiological actions of regulators of G-protein signaling (RGS) proteins. Life Sci. 74 (2003) 163-171
    • (2003) Life Sci. , vol.74 , pp. 163-171
    • Ishii, M.1    Kurachi, Y.2
  • 23
    • 0036129270 scopus 로고    scopus 로고
    • RGS2: a multifunctional regulator of G-protein signaling
    • Kehrl J.H., and Sinnarajah S. RGS2: a multifunctional regulator of G-protein signaling. Int. J. Biochem. Cell B 32 (2001) 432-438
    • (2001) Int. J. Biochem. Cell B , vol.32 , pp. 432-438
    • Kehrl, J.H.1    Sinnarajah, S.2
  • 24
    • 33846503153 scopus 로고    scopus 로고
    • Kinzer-Ursem, T.L., Linderman, J.J., 2007. Both ligand- and cell-specific parameters control ligand agonism in a kinetic model of G protein-coupled receptor signaling. PLoS Comput. Biol. 3 (1), e6. doi:10.1371/journal.pcbi.0030006.
    • Kinzer-Ursem, T.L., Linderman, J.J., 2007. Both ligand- and cell-specific parameters control ligand agonism in a kinetic model of G protein-coupled receptor signaling. PLoS Comput. Biol. 3 (1), e6. doi:10.1371/journal.pcbi.0030006.
  • 25
    • 0030907376 scopus 로고    scopus 로고
    • A new family of G-protein regulators-the RGS proteins
    • Koelle M.R. A new family of G-protein regulators-the RGS proteins. Curr. Biol. 9 (1997) 143-147
    • (1997) Curr. Biol. , vol.9 , pp. 143-147
    • Koelle, M.R.1
  • 26
    • 14844318077 scopus 로고    scopus 로고
    • When kinases meet mathematics: the systems biology of MAPK signalling
    • Kolch W., Calder F., and Gilbert D. When kinases meet mathematics: the systems biology of MAPK signalling. FEBS Lett. 579 (2005) 1891-1895
    • (2005) FEBS Lett. , vol.579 , pp. 1891-1895
    • Kolch, W.1    Calder, F.2    Gilbert, D.3
  • 27
    • 0036408793 scopus 로고    scopus 로고
    • Module dynamics of the GnRH signal transduction network
    • Krauker D.C., Page K.M., and Sealfon S. Module dynamics of the GnRH signal transduction network. J. Theor. Biol. 218 (2002) 457-470
    • (2002) J. Theor. Biol. , vol.218 , pp. 457-470
    • Krauker, D.C.1    Page, K.M.2    Sealfon, S.3
  • 28
    • 3242793327 scopus 로고    scopus 로고
    • Historical review: a brief history and personal retrospective of seven-transmembrane receptors
    • Lefkowitz R.J. Historical review: a brief history and personal retrospective of seven-transmembrane receptors. Trends Pharmacol. Sci. 25 (2004) 413-422
    • (2004) Trends Pharmacol. Sci. , vol.25 , pp. 413-422
    • Lefkowitz, R.J.1
  • 29
    • 17644402459 scopus 로고    scopus 로고
    • Transduction of receptor signals by beta-arrestins
    • Lefkowitz R.J., and Shenoy S. Transduction of receptor signals by beta-arrestins. Science 308 (2005) 512-517
    • (2005) Science , vol.308 , pp. 512-517
    • Lefkowitz, R.J.1    Shenoy, S.2
  • 31
    • 0032938716 scopus 로고    scopus 로고
    • Regulation of tyrosine kinase cascades by G-protein-coupled receptors
    • Luttrell L., Daaka Y., and Lefkowitz R. Regulation of tyrosine kinase cascades by G-protein-coupled receptors. Curr. Opin. Cell Biol. 11 (1999) 177-183
    • (1999) Curr. Opin. Cell Biol. , vol.11 , pp. 177-183
    • Luttrell, L.1    Daaka, Y.2    Lefkowitz, R.3
  • 32
    • 0035956983 scopus 로고    scopus 로고
    • Activation and targeting of extracellular signal-regulated kinases by beta-arrestin scaffolds
    • Luttrell L.M., Roudabush F.L., Choy E.W., Miller W.E., and Field M.E. Activation and targeting of extracellular signal-regulated kinases by beta-arrestin scaffolds. Proc. Natl. Acad. Sci. USA 98 (2001) 2449-2454
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 2449-2454
    • Luttrell, L.M.1    Roudabush, F.L.2    Choy, E.W.3    Miller, W.E.4    Field, M.E.5
  • 33
    • 33746013755 scopus 로고    scopus 로고
    • Cellular mechanisms that determine selective RGS protein regulation of G protein-coupled receptor signaling
    • Neitzel K.L., and Hepler J.R. Cellular mechanisms that determine selective RGS protein regulation of G protein-coupled receptor signaling. Semin. Cell Dev. Biol. 17 (2006) 383-389
    • (2006) Semin. Cell Dev. Biol. , vol.17 , pp. 383-389
    • Neitzel, K.L.1    Hepler, J.R.2
  • 35
    • 0033592303 scopus 로고    scopus 로고
    • Modeling activation and desensitization of G-protein coupled receptors provides insight into ligand efficacy
    • Riccobene T.A., Omann G.M., and Linderman J.J. Modeling activation and desensitization of G-protein coupled receptors provides insight into ligand efficacy. J. Theor. Biol. 200 (1999) 207-222
    • (1999) J. Theor. Biol. , vol.200 , pp. 207-222
    • Riccobene, T.A.1    Omann, G.M.2    Linderman, J.J.3
  • 37
    • 0037376655 scopus 로고    scopus 로고
    • Sniffers, buzzers, toggles and blinkers: dynamics of regulatory and signaling pathways in the cell
    • Tyson J., Chen C., and Novák B. Sniffers, buzzers, toggles and blinkers: dynamics of regulatory and signaling pathways in the cell. Curr. Opin. Cell Biol. 14 (2003) 221-231
    • (2003) Curr. Opin. Cell Biol. , vol.14 , pp. 221-231
    • Tyson, J.1    Chen, C.2    Novák, B.3
  • 38
    • 0025000745 scopus 로고
    • Duration of phasic electrical activity of the hypothalamic gonadotropin-releasing hormone pulse generator and dynamics of luteinizing hormone pulses in the rhesus monkey
    • Williams C.L., Thalabard J.C., O'Byrne K.T., Grosser P., Nishiara M., Hotchkiss J., and Knobil E. Duration of phasic electrical activity of the hypothalamic gonadotropin-releasing hormone pulse generator and dynamics of luteinizing hormone pulses in the rhesus monkey. Proc. Natl. Acad. Sci. USA 87 (1990) 8580-8582
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 8580-8582
    • Williams, C.L.1    Thalabard, J.C.2    O'Byrne, K.T.3    Grosser, P.4    Nishiara, M.5    Hotchkiss, J.6    Knobil, E.7
  • 39
    • 68749086702 scopus 로고    scopus 로고
    • From the static to the dynamic: three models of signal transduction in G-protein coupled receptors
    • Christopoulos A. (Ed)
    • Woolf P.J., and Linderman J.J. From the static to the dynamic: three models of signal transduction in G-protein coupled receptors. In: Christopoulos A. (Ed). Biomedical Applications of Computer Modelling (2000) 87-108
    • (2000) Biomedical Applications of Computer Modelling , pp. 87-108
    • Woolf, P.J.1    Linderman, J.J.2
  • 40
    • 0034731482 scopus 로고    scopus 로고
    • Timing is everything: the role of kinetics in G protein activation
    • Woolf P.J., Neubig R.R., and Linderman J.J. Timing is everything: the role of kinetics in G protein activation. Life Sci. 68 (2000) 647-658
    • (2000) Life Sci. , vol.68 , pp. 647-658
    • Woolf, P.J.1    Neubig, R.R.2    Linderman, J.J.3
  • 41
    • 0035925037 scopus 로고    scopus 로고
    • Uncovering biases in high throughput screens of G-protein coupled receptors
    • Woolf P.J., Kenakin T.P., and Linderman J.J. Uncovering biases in high throughput screens of G-protein coupled receptors. J. Theor. Biol. 208 (2001) 403-418
    • (2001) J. Theor. Biol. , vol.208 , pp. 403-418
    • Woolf, P.J.1    Kenakin, T.P.2    Linderman, J.J.3
  • 42
    • 33846376810 scopus 로고    scopus 로고
    • How regulators of G protein signaling achieve selective regulation
    • Xie G., and Palmer P.P. How regulators of G protein signaling achieve selective regulation. J. Mol. Biol. 366 (2007) 349-365
    • (2007) J. Mol. Biol. , vol.366 , pp. 349-365
    • Xie, G.1    Palmer, P.P.2
  • 43
    • 0032560061 scopus 로고    scopus 로고
    • G-protein signaling: fine-tuning signaling kinetics
    • Zerangue N., and Jan L.Y. G-protein signaling: fine-tuning signaling kinetics. Curr. Biol. 8 (1998) 313-316
    • (1998) Curr. Biol. , vol.8 , pp. 313-316
    • Zerangue, N.1    Jan, L.Y.2
  • 44
    • 0037470041 scopus 로고    scopus 로고
    • A spatial focusing model for G protein signals: RGS protein-mediated kinetic scaffolding
    • Zhong H., Wade S., Woolf P., Linderman J., Clark M., Traynor J., and Neubig R. A spatial focusing model for G protein signals: RGS protein-mediated kinetic scaffolding. J. Biol. Chem. 278 (2003) 7278-7284
    • (2003) J. Biol. Chem. , vol.278 , pp. 7278-7284
    • Zhong, H.1    Wade, S.2    Woolf, P.3    Linderman, J.4    Clark, M.5    Traynor, J.6    Neubig, R.7
  • 45
    • 36348932213 scopus 로고    scopus 로고
    • Modeling specificity in the yeast MAPK signaling networks
    • Zou X., Peng T., and Pan Z. Modeling specificity in the yeast MAPK signaling networks. J. Theor. Biol. 250 (2008) 139-155
    • (2008) J. Theor. Biol. , vol.250 , pp. 139-155
    • Zou, X.1    Peng, T.2    Pan, Z.3


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