Timing is everything: The role of kinetics in G protein activation

Life Sciences

Volumn 68, Issue 6, 2000, Pages 647-658

  Shea, L D ^a,d   Neubig, R R ^b   Linderman, J J ^c  

^a Northwestern University   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

^d NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Mathematical model; Precoupling; RGS; Ternary complex model

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; PROTEIN RGS; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING KINETICS; CHEMICAL REACTION KINETICS; DRUG DESIGN; DRUG EFFICACY; DRUG PROTEIN BINDING; MATHEMATICAL MODEL; MOLECULAR DYNAMICS; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION;

BIOTRANSFORMATION; GTP-BINDING PROTEINS; KINETICS; LIGANDS; MODELS, BIOLOGICAL;

EID: 0034731482     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(00)00977-2     Document Type: Article

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