Regulation of KATP channel expression and activity by the sur1 nucleotide binding fold 1

Channels

Volumn 1, Issue 4, 2007, Pages 315-323

  Masia, Ricard ^a   Caputa, George ^a   Nichols, Colin G ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

ABC transporter; NBF1; Split constructs; Sulfonylurea receptor

Indexed keywords

ABC TRANSPORTER; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; DRUG RECEPTOR; INWARDLY RECTIFYING POTASSIUM CHANNEL; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.2; PROTEASOME; SULFONYLUREA RECEPTOR;

ANIMAL; ARTICLE; BINDING SITE; CELL MEMBRANE POTENTIAL; CELL STRAIN COS1; CERCOPITHECUS; CHANNEL GATING; CHEMISTRY; ENDOPLASMIC RETICULUM; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; HAMSTER; METABOLISM; MOUSE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FOLDING;

ADENOSINE DIPHOSPHATE; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BINDING SITES; CERCOPITHECUS AETHIOPS; COS CELLS; CRICETINAE; ENDOPLASMIC RETICULUM; GENE EXPRESSION REGULATION; ION CHANNEL GATING; KATP CHANNELS; MEMBRANE POTENTIALS; MICE; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FOLDING; RECEPTORS, DRUG; TRANSFECTION;

EID: 53049105327     PISSN: 19336950     EISSN: 19336969     Source Type: Journal    
DOI: 10.4161/chan.5083     Document Type: Article

References (47)

1. Clement JP, Kunjilwar K, Gonzalez G, Schwanstecher M, Panten U, Aguilar-Bryan L, Bryan J. Association and stoichiometry of KATP channel subunits. Neuron 1997; 18: 827-38.
2. Shyng S, Nichols CG. Octameric stoichiometry of the KATP channel complex. J Gen Physiol 1997; 110: 655-64.
3. Seino S. ATP-sensitive potassium channels: A model of heteromultimeric potassium channel/receptor assemblies. Annu Rev Physiol 1999; 61: 337-362.
4. Babenko AP, Bryan J. Sur domains that associate with and gate KATP pores define a novel gatekeeper. J Biol Chem 2003; 278: 41577-80.
5. Chan KW, Zhang H, Logothetis DE. N-terminal transmembrane domain of the SUR controls trafficking and gating of Kir6 channel subunits. EMBO J 2003; 22: 3833-43.
6. Tucker SJ, Gribble FM, Zhao C, Trapp S, Ashcroft FM. Truncation of Kir6.2 produces ATP-sensitive K+ channels in the absence of the sulphonylurea receptor. Nature 1997; 387: 179-83.
7. Tanabe K, Tucker SJ, Matsuo M, Proks P, Ashcroft FM, Seino S, Amachi T, Ueda K. Direct photoaffinity labeling of the Kir6.2 subunit of the ATP-sensitive K+ channel by 8-Azido-ATP. J Biol Chem 1999; 274: 3931-3933.
8. Gribble FM, Tucker SJ, Ashcroft FM. The interaction of nucleotides with the tolbutamide block of cloned ATP-sensitive K+ channel currents expressed in Xenopus oocytes: A reinterpretation. J Physiol 1997; 504: 35-45.
9. Schwanstecher M, Sieverding C, Dorschner H, Gross I, Aguilar-Bryan L, Schwanstecher C, Bryan J. Potassium channel openers require ATP to bind to and act through sulfonylurea receptors. EMBO J 1998; 17: 5529-35.
10. Gribble FM, Tucker SJ, Haug T, Ashcroft FM. MgADP activates the b cell KATP channel by interaction with its SUR1 subunit. Proc Natl Acad Sci USA 1998; 95: 7185-90.
11. Nichols CG, Shyng SL, Nestorowicz A, Glaser B, Clement JP, Gonzalez G, Aguilar-bryan L, Permutt MA, Bryan J. Adenosine diphosphate as an intracellular regulator of insulin secretion. Science 1996; 272: 1785-1787.
12. Hopfner KP, Karcher A, Shin DS, Craig L, Arthur LM, Carney JP, Tainer JA. Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily. Cell 2000; 101: 789-800.
13. Locher KP, Lee AT, Rees DC. The E. coli BtuCD structure: A framework for ABC transporter architecture and mechanism. Science 2002; 296: 1091-8.
14. Moody JE, Millen L, Binns D, Hunt JF, Thomas PJ. Cooperative, ATP-dependent association of the nucleotide binding cassettes during the catalytic cycle of ATP-binding cassette transporters. J Biol Chem 2002; 277: 21111-4.
15. Smith PC, Karpowich N, Millen L, Moody JE, Rosen J, Thomas PJ, Hunt JF. ATP binding to the motor domain from an ABC transporter drives formation of a nucleotide sandwich dimer. Mol Cell 2002; 10: 139-49.
16. Gribble FM, Tucker SJ, Ashcroft FM. The essential role of the Walker A motifs of SUR1 in KATP channel activation by MgADP and diazoxide. EMBO J 1997; 16: 1145-52.
17. Shyng S, Ferrigni T, Nichols CG. Regulation of KATP channel activity by diazoxide and MgADP: Distinct functions of the two nucleotide binding folds of the sulfonylurea receptor. J Gen Physiol 1997; 110: 643-54.
18. Zerangue N, Malan MJ, Fried SR, Dazin PF, Jan YN, Jan LY, Schwappach B. Analysis of endoplasmic reticulum trafficking signals by combinatorial screening in mammalian cells. Proc Natl Acad Sci USA 2001; 98: 2431-6.
19. Zerangue N, Schwappach B, Jan YN, Jan LY. A new ER trafficking signal regulates the subunit stoichiometry of plasma membrane KATP channels. Neuron 1999; 22: 537-48.
20. Conti LR, Radeke CM, Shyng SL, Vandenberg CA. Transmembrane topology of the sulfonylurea receptor SUR1. J Biol Chem 2001; 276: 41270-8.
21. Raab-Graham KF, Cirilo LJ, Boettcher AA, Radeke CM, Vandenberg CA. Membrane topology of the amino-terminal region of the sulfonylurea receptor. J Biol Chem 1999; 274: 29122-9.
22. Conti LR, Radeke CM, Vandenberg CA. Membrane targeting of ATP-sensitive potassium channel: Effects of glycosylation on surface expression. J Biol Chem 2002; 277: 25416-22.
23. Cartier EA, Conti LR, Vandenberg CA, Shyng SL. Defective trafficking and function of KATP channels caused by a sulfonylurea receptor 1 mutation associated with persistent hyperinsulinemic hypoglycemia of infancy. Proc Natl Acad Sci USA 2001; 98: 2882-7.
24. Partridge CJ, Beech DJ, Sivaprasadarao A. Identification and pharmacological correction of a membrane trafficking defect associated with a mutation in the sulfonylurea receptor causing familial hyperinsulinism. J Biol Chem 2001; 276: 35947-52.
25. Taschenberger G, Mougey A, Shen S, Lester LB, LaFranchi S, Shyng SL. Identification of a familial hyperinsulinism-causing mutation in the sulfonylurea receptor 1 that prevents normal trafficking and function of KATP channels. J Biol Chem 2002; 277: 17139-46.
26. Yan F, Lin CW, Weisiger E, Cartier EA, Taschenberger G, Shyng SL. Sulfonylureas correct trafficking defects of ATP-sensitive potassium channels caused by mutations in the sulfonylurea receptor. J Biol Chem 2004; 279: 11096-105.
27. Yan FF, Lin CW, Cartier EA, Shyng SL. Role of ubiquitin-proteasome degradation pathway in biogenesis efficiency of b-cell ATP-sensitive potassium channels. Am J Physiol Cell Physiol 2005; 289: C1351-9.
28. Inagaki N, Gonoi T, Clement JP, Namba N, Inazawa J, Gonzalez G, Aguilar-Bryan L, Seino S, Bryan J. Reconstitution of IKATP: An inward rectifier subunit plus the sulfonylurea receptor. Science 1995; 270: 1166-70.
29. Aguilar-Bryan L, Nichols CG, Wechsler SW, Clement JPt, Boyd AEr, Gonzalez G, Herrera-Sosa H, Nguy K, Bryan J, Nelson DA. Cloning of the b cell high-affinity sulfonylurea receptor: A regulator of insulin secretion. Science 1995; 268: 423-426.
30. Lederer WJ, Nichols CG. Nucleotide modulation of the activity of rat heart ATP-sensitive K+ channels in isolated membrane patches. J Physiol 1989; 419: 193-211.
31. Campbell JD, Proks P, Lippiat JD, Sansom MSP, Ashcroft FM. Identification of a functionally important negatively charged residue within the second catalytic site of the SUR1 nucleotide-binding domains. Diabetes 2004; 53: S123-127.
32. Sakura H, Trapp S, Liss B, Ashcroft FM. Altered functional properties of KATP channel conferred by a novel splice variant of SUR1. J Physiol 1999; 521: 337-50.
33. Ueda K, Komine J, Matsuo M, Seino S, Amachi T. Cooperative binding of ATP and MgADP in the sulfonylurea receptor is modulated by glibenclamide. Proc Natl Acad Sci USA 1999; 96: 1268-72.
34. Mikhailov MV, Campbell JD, de Wet H, Shimomura K, Zadek B, Collins RF, Sansom MS, Ford RC, Ashcroft FM. 3-D structural and functional characterization of the purified KATP channel complex Kir6.2-SUR1. EMBO J 2005; 24: 4166-75.
35. Hough E, Mair L, Mackenzie W, Sivaprasadarao A. Expression, purification, and evidence for the interaction of the two nucleotide-binding folds of the sulphonylurea receptor. Biochem Biophys Res Commun 2002; 294: 191-7.
36. Mikhailov MV, Ashcroft SJH. Interactions of the sulfonylurea receptor 1 subunit in the molecular assembly of b-cell K-ATP channels. J Biol Chem 2000; 275: 3360-3364.
37. Dawson RJ, Locher KP. Structure of a bacterial multidrug ABC transporter. Nature 2006; 443: 180-5.
38. Matsuo M, Kioka N, Amachi T, Ueda K. ATP binding properties of the nucleotide-binding folds of SUR1. J Biol Chem 1999; 274: 37479-82.
39. Ueda K, Inagaki N, Seino S. MgADP antagonism to Mg2+-independent ATP binding of the sulfonylurea receptor SUR1. J Biol Chem 1997; 272: 22983-6.
40. Masia R, Enkvetchakul D, Nichols CG. Differential nucleotide regulation of KATP channels by SUR1 and SUR2A. J Mol Cell Cardiol 2005; 39: 491-501.
41. Mikhailov MV, Mikhailova EA, Ashcroft SJ. Investigation of the molecular assembly of b-cell KATP channels. FEBS Lett 2000; 482: 59-64.
42. Mikhailov MV, Proks P, Ashcroft FM, Ashcroft SJ. Expression of functionally active ATP-sensitive K-channels in insect cells using baculovirus. FEBS Lett 1998; 429: 390-4.
43. Chan KW, Csanady L, Seto-Young D, Nairn AC, Gadsby DC. Severed molecules functionally define the boundaries of the cystic fibrosis transmembrane conductance regulator's NH2-terminal nucleotide binding domain. J Gen Physiol 2000; 116: 163-80.
44. Shyng SL, Ferrigni T, Shepard JB, Nestorowicz A, Glaser B, Permutt MA, Nichols CG. Functional analyses of novel mutations in the sulfonylurea receptor 1 associated with persistent hyperinsulinemic hypoglycemia of infancy. Diabetes 1998; 47: 1145-51.
45. Matsuo M, Tanabe K, Kioka N, Amachi T, Ueda K. Different binding properties and affinities for ATP and ADP among sulfonylurea receptor subtypes, SUR1, SUR2A, and SUR2B. J Biol Chem 2000; 275: 28757-63.
46. Tornovsky S, Crane A, Cosgrove KE, Hussain K, Lavie J, Heyman M, Nesher Y, Kuchinski N, Ben-Shushan E, Shatz O, Nahari E, Potikha T, Zangen D, Tenenbaum-Rakover Y, de Vries L, Argente J, Gracia R, Landau H, Eliakim A, Lindley K, Dunne MJ, Aguilar-Bryan L, Glaser B. Hyperinsulinism of infancy: Novel ABCC8 and KCNJ11 mutations and evidence for additional locus heterogeneity. J Clin Endocrinol Metab 2004; 89: 6224-34.
47. Schwappach B, Zerangue N, Jan YN, Jan LY. Molecular basis for KATP assembly: Transmembrane interactions mediate association of a K+ channel with an ABC transporter. Neuron 2000; 26: 155-67.