Regulation of vascular endothelial growth factor expression by homeodomain-interacting protein kinase-2

Journal of Experimental and Clinical Cancer Research

Volumn 27, Issue 1, 2008, Pages

  Puca, Rosa ^a   Nardinocchi, Lavinia ^a   D'Orazi, Gabriella ^a,b  

^a REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

^b UNIVERSITY OF CHIETI   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; BETA CATENIN; GLYCOGEN SYNTHASE KINASE 3BETA; HOMEODOMAIN INTERACTING PROTEIN KINASE 2; PROTEIN P53; VASCULOTROPIN; CARRIER PROTEIN; CTNNB1 PROTEIN, HUMAN; HIPK2 PROTEIN, HUMAN; MESSENGER RNA; PROTEASOME; PROTEIN SERINE THREONINE KINASE; VASCULOTROPIN A;

ARTICLE; BREAST CANCER; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LUNG ADENOCARCINOMA; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; GENE EXPRESSION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; GENETICS; METABOLISM; TUMOR CELL LINE;

BETA CATENIN; CARRIER PROTEINS; CELL LINE, TUMOR; DOWN-REGULATION; GENE EXPRESSION; HUMANS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN-SERINE-THREONINE KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSCRIPTION, GENETIC; TRANSFECTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 52949128032     PISSN: None     EISSN: 17569966     Source Type: Journal    
DOI: 10.1186/1756-9966-27-22     Document Type: Article

References (29)

1. Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors. YH Kim CY Choi SJ Lee MA Conti Y Kim, J Biol Chem 1998 273 25875 25879 10.1074/jbc.273.40.25875 9748262
2. HIPK2: a multitalented partner for transcription factors in DNA damage response and development. C Rinaldo A Prodosmo F Siepi S Soddu, Biochem Cell Biol 2007 85 411 418 10.1139/O07-071 17713576
3. Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis. G D'Orazi B Cecchinelli T Bruno I Manni Y Higashimoto S Saito M Gostissa S Coen A Marchetti G Del Sal G Piaggio M Fanciulli E Appella S Soddu, Nat Cell Biol 2002 4 11 19 10.1038/ncb714 11780126
4. Regulation of p53 activity by its interaction with homeodomain- interacting protein kinase-2. TG Hofmann A Moller H Sirma H Zentgraf Y Taya W Droge H Will ML Schmitz, Nat Cell Biol 2002 4 1 10 10.1038/ncb715 11740489
5. Homeodomain interacting protein kinase 2 promotes apoptosis by downregulating the transcriptional corepressor CtBP. Q Zhang Y Yoshimatsu J Hildebrabd SM Frisch RH Goodman, Cell 2003 115 177 186 10.1016/S0092-8674(03) 00802-X 14567915
6. HIPK2 inhibits both MDM2 gene and protein by, respectively, p53-dependent and independent regulations. V Di Stefano M Mattiussi A Sacchi G D'Orazi, FEBS Lett 2005 579 5473 5480 10.1016/j.febslet.2005.09.008 16212962
7. Axin stimulates p53 functions by activation of HIPK2 kinase through multimeric complex formation. Y Rui Z Xu S Lin Q Li H Rui W Luo H-M Zhou P-Y Cheung Z Wu Z Ye P Li J Han S-C Lin, EMBO J 2004 23 4583 4594 15526030 10.1038/sj.emboj.7600475
8. Binding of GSK3/beta to the APC-beta-catenin complex and regulation of complex assembly. B Rubinfeld I Albert E Porfiri C Fiol S Munemitsu P Polakis, Science 1996 272 1023 1026 10.1126/science.272.5264.1023 8638126
9. Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin. S Ikeda S Kishida H Yamamoto H Murai S Koyanma Kikuchi, EMBO J 1998 17 1371 1384 9482734 10.1093/emboj/17.5.1371
10. Control of β-catenin phosphorylation/degradation by a dual-kinase mechanism. C Liu Y Li M Semenov C Han G-H Baeg Y Tan Z Zhang X Lin X He, Cell 2002 108 837 847 10.1016/S0092-8674(02)00685-2 11955436
11. Downregulation of β-catenin by human Axin and its association with the APC tumor suppressor, β-catenin and GSK3/β MJ Hart R de los Santos IN Albert B Rubinfeld P Polakis, Curr Biol 1998 8 573 581 10.1016/S0960- 9822(98)70226-X 9601641
12. The many ways of Wnt in cancer. P Polakis, Curr Opin Genet Dev 2007 17 45 51 10.1016/j.gde.2006.12.007 17208432
13. The oncogenic activation of β-catenin. P Polakis, Curr Opin Genet Dev 1999 9 15 21 10.1016/S0959-437X(99)80003-3 10072352
14. Identification of c-Myc as a target of the APC pathway. T He A Sparks C Rago H Hermeking L Zawel L da Costa P Morin B Vogelstein K Kinzler, Science 1998 281 1509 1512 10.1126/science.281.5382.1509 9727977
15. The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway. M Shtutman J Zhurinsky I Simcha C Albanese M D'Amico R Pestell A Ben-Ze'ev, Proc Natl Acad Sci USA 1999 96 5522 5527 10318916 10.1073/pnas.96.10.5522
16. Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. O Tetsuo F McCormick, Nature 1999 398 422 426 10.1038/18884 10201372
17. Target genes of β-catenin-T cell-factor/lymphoid-enhancer-factor signalling in human colorectal carcinomas. B Mann M Gelos A Siedow ML Hanski A Gratchev M Ilyas WF Bodmer MP Moyer EO Riecken HJ Buhr C Hanski, Proc Natl Acad Sci USA 1999 96 1603 1608 9990071 10.1073/pnas.96.4.1603
18. Regulation of vascular endothelial growth factor by the Wnt and K-ras pathways in colonic neoplasia. X Zhang JP Gaspard DC Chung, Cancer Res 2001 61 6050 6054 11507052
19. Angiogenesis in cancer, vascular, rheumatoid and other disease. J Folkman, Nature Medicine 1995 1 27 31 10.1038/nm0195-27 7584949
20. Vascular permeability factor/vascular endothelial growth factor: a critical cytokine in tumor angiogenesis and a potential target for diagnosis and therap. HF Dvorak, J Clin Oncol 2002 20 4368 4380 10.1200/JCO.2002.10.088 12409337
21. Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumor growth in viv. KJ Kim B Li J Winer M Armanini N Gillet HS Philipps N Ferrara, Nature 1993 362 841 844 10.1038/362841a0 7683111
22. HIPK2 represses β-catenin-mediated transcription, epidermal stem cell expansion, and skin tumorigenesis. G Wei S Ku GK Ma S Saito AA Tang J Zhang J-H Mao E Appella A Balmain EJ Huang, Proc Natl Acad Sci USA 2007 104 13040 13045 17666529 10.1073/pnas.0703213104
23. High-efficiency transformation of mammalian cells by plasmid DNA. C Chen H Okayama, Mol Cell Biol 1987 7 2754 2756 3670292
24. Down-regulation of beta-catenin by activated p53. E Sadot B Geiger M Oren A Ben-Ze'ev, Mol Cell Biol 2001 21 6768 6781 11564862 10.1128/MCB.21.20.6768- 6781.2001
25. Expression and activity of vascular endothelial growth factor and metalloproteinases in alveolar and embryonal rhabdomyosarcoma cell lines. M Onisto ML Slongo L Gregnanin T Gastaldi M Carli A Rosolen, Int J Oncol 2005 27 3 791 798 16077930
26. Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells. V Stambolic L Ruel JR Woodgett, Curr Biol 1996 6 1664 1668 10.1016/S0960-9822(02)70790-2 8994831
27. The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glicogen synthase kinase 3. C Yost M Torres J Miller E Huang D Kimelman R Moon, Genes Dev 1996 10 1443 1454 10.1101/gad.10.12.1443 8666229
28. Mechanisms of disease: angiogenesis and the management of breast cancer. S Banerjee M Dowsett A Ashworth L-A Martin, Nature Clinical Practice 2007 4 536 550 10.1038/ncponc0905 17728712
29. Exogenous expression of beta-catenin regulates contact inhibition, anchorage independent growth, anoikis, and radiation-induced cell cycle arrest. K Orford C Orford S Byers, J Cell Biol 1999 146 855 867 10459019 10.1083/jcb.146.4.855