-
1
-
-
4644309196
-
The function of animal miRNAs
-
Ambros V. The function of animal miRNAs. Nature 2004;431:350-355.
-
(2004)
Nature
, vol.431
, pp. 350-355
-
-
Ambros, V.1
-
2
-
-
22144489833
-
RNAi: The nuts and bolts of the RISC machine
-
Filipowicz W. RNAi: the nuts and bolts of the RISC machine. Cell 2005;122:17-20.
-
(2005)
Cell
, vol.122
, pp. 17-20
-
-
Filipowicz, W.1
-
3
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism and function
-
Bartel DP. MicroRNAs: genomics, biogenesis, mechanism and function. Cell 2004;116:281-297.
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
4
-
-
22144437679
-
Silence from within: Endogenous siRNAs and miRNAs
-
Sontheimer EJ, Carthew RW. Silence from within: endogenous siRNAs and miRNAs. Cell 2005;122:9-12.
-
(2005)
Cell
, vol.122
, pp. 9-12
-
-
Sontheimer, E.J.1
Carthew, R.W.2
-
5
-
-
4644223259
-
Mechanisms of gene silencing by double-stranded RNA
-
Meister G, Tuschl T. Mechanisms of gene silencing by double-stranded RNA. Nature 2004;431:343-349.
-
(2004)
Nature
, vol.431
, pp. 343-349
-
-
Meister, G.1
Tuschl, T.2
-
6
-
-
35348996554
-
Specialization and evolution of endogenous small RNA pathways
-
Chapman EJ, Carrington JC. Specialization and evolution of endogenous small RNA pathways. Nat Rev Genet 2007;8:884-896.
-
(2007)
Nat Rev Genet
, vol.8
, pp. 884-896
-
-
Chapman, E.J.1
Carrington, J.C.2
-
7
-
-
0037072661
-
Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi
-
Volpe TA, Kidner C, Hall IM, Teng G, Grewal SI, Martienssen RA. Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi. Science 2002;297:1833-1837.
-
(2002)
Science
, vol.297
, pp. 1833-1837
-
-
Volpe, T.A.1
Kidner, C.2
Hall, I.M.3
Teng, G.4
Grewal, S.I.5
Martienssen, R.A.6
-
8
-
-
0037474126
-
ARGONAUTE4 control of locus-specific siRNA accumulation and DNA and histone methylation
-
Zilberman D, Cao X, Jacobsen SE. ARGONAUTE4 control of locus-specific siRNA accumulation and DNA and histone methylation. Science 2003;299:716-719.
-
(2003)
Science
, vol.299
, pp. 716-719
-
-
Zilberman, D.1
Cao, X.2
Jacobsen, S.E.3
-
9
-
-
33746492419
-
Molecular biology. A new RNA dimension to genome control
-
Carthew RW. Molecular biology. A new RNA dimension to genome control. Science 2006;313:305-306.
-
(2006)
Science
, vol.313
, pp. 305-306
-
-
Carthew, R.W.1
-
10
-
-
36749037521
-
The Piwi-piRNA pathway provides an adaptive defense in the transposon arms race
-
Aravin AA, Hannon GJ, Brennecke J. The Piwi-piRNA pathway provides an adaptive defense in the transposon arms race. Science 2007;318:761-764.
-
(2007)
Science
, vol.318
, pp. 761-764
-
-
Aravin, A.A.1
Hannon, G.J.2
Brennecke, J.3
-
11
-
-
33746502166
-
A distinct small RNA pathway silences selfish genetic elements in the germline
-
Vagin VV, Sigova A, Li C, Seitz H, Gvozdev V, Zamore PD. A distinct small RNA pathway silences selfish genetic elements in the germline. Science 2006;313:320-324.
-
(2006)
Science
, vol.313
, pp. 320-324
-
-
Vagin, V.V.1
Sigova, A.2
Li, C.3
Seitz, H.4
Gvozdev, V.5
Zamore, P.D.6
-
12
-
-
34247525481
-
-
Lin H. piRNAs in the germ line. Science 2007;316:397.
-
Lin H. piRNAs in the germ line. Science 2007;316:397.
-
-
-
-
13
-
-
37648998629
-
Getting to the root of miRNA-mediated gene silencing
-
Eulalio A, Huntzinger E, Izaurralde E. Getting to the root of miRNA-mediated gene silencing. Cell 2008;132:9-14.
-
(2008)
Cell
, vol.132
, pp. 9-14
-
-
Eulalio, A.1
Huntzinger, E.2
Izaurralde, E.3
-
14
-
-
22144436236
-
The role of the RNAi machinery in heterochromatin formation
-
Wassenegger M. The role of the RNAi machinery in heterochromatin formation. Cell 2005;122:13-16.
-
(2005)
Cell
, vol.122
, pp. 13-16
-
-
Wassenegger, M.1
-
15
-
-
0033634943
-
The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor
-
Slack FJ, Basson M, Liu Z, Ambros V, Horvitz HR, Ruvkun G. The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor. Mol Cell 2000;5:659-669.
-
(2000)
Mol Cell
, vol.5
, pp. 659-669
-
-
Slack, F.J.1
Basson, M.2
Liu, Z.3
Ambros, V.4
Horvitz, H.R.5
Ruvkun, G.6
-
16
-
-
0024963695
-
A hierarchy of regulatory genes controls a larva-to-adult developmental switch in C. elegans
-
Ambros V. A hierarchy of regulatory genes controls a larva-to-adult developmental switch in C. elegans. Cell 1989;57:49-57.
-
(1989)
Cell
, vol.57
, pp. 49-57
-
-
Ambros, V.1
-
17
-
-
0037197803
-
Identification of tissue-specific microRNAs from mouse
-
Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T. Identification of tissue-specific microRNAs from mouse. Curr Biol 2002;12:735-739.
-
(2002)
Curr Biol
, vol.12
, pp. 735-739
-
-
Lagos-Quintana, M.1
Rauhut, R.2
Yalcin, A.3
Meyer, J.4
Lendeckel, W.5
Tuschl, T.6
-
18
-
-
34547579291
-
MicroRNAs in the human heart: A clue to fetal gene reprogramming in heart failure
-
Thum T, Galuppo P, Wolf C, Fiedler J, Kneitz S, van Laake LW et al. MicroRNAs in the human heart: a clue to fetal gene reprogramming in heart failure. Circulation 2007;116:258-267.
-
(2007)
Circulation
, vol.116
, pp. 258-267
-
-
Thum, T.1
Galuppo, P.2
Wolf, C.3
Fiedler, J.4
Kneitz, S.5
van Laake, L.W.6
-
19
-
-
33344477448
-
Genomics of microRNA
-
Kim VN, Nam JW. Genomics of microRNA. Trends Genet 2006;22:165-173.
-
(2006)
Trends Genet
, vol.22
, pp. 165-173
-
-
Kim, V.N.1
Nam, J.W.2
-
20
-
-
18744367544
-
Clustering and conservation patterns of human microRNAs
-
Altuvia Y, Landgraf P, Lithwick G, Elefant N, Pfeffer S, Aravin A et al. Clustering and conservation patterns of human microRNAs. Nucleic Acids Res 2005;33:2697-2706.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 2697-2706
-
-
Altuvia, Y.1
Landgraf, P.2
Lithwick, G.3
Elefant, N.4
Pfeffer, S.5
Aravin, A.6
-
22
-
-
8144225486
-
MicroRNA genes are transcribed by RNA polymerase II
-
Lee Y, Kim M, Han J, Yeom KH, Lee S, Baek SH et al. MicroRNA genes are transcribed by RNA polymerase II. EMBO J 2004;23:4051-4060.
-
(2004)
EMBO J
, vol.23
, pp. 4051-4060
-
-
Lee, Y.1
Kim, M.2
Han, J.3
Yeom, K.H.4
Lee, S.5
Baek, S.H.6
-
24
-
-
0141843656
-
The nuclear RNase III Drosha initiates microRNA processing
-
Lee Y, Ahn C, Han J, Choi H, Kim J, Yim J et al. The nuclear RNase III Drosha initiates microRNA processing. Nature 2003;425:415- 419.
-
(2003)
Nature
, vol.425
, pp. 415-419
-
-
Lee, Y.1
Ahn, C.2
Han, J.3
Choi, H.4
Kim, J.5
Yim, J.6
-
25
-
-
34447097693
-
Intronic microRNA precursors that bypass Drosha processing
-
Ruby JG, Jan CH, Bartel DP. Intronic microRNA precursors that bypass Drosha processing. Nature 2007;448:83-86.
-
(2007)
Nature
, vol.448
, pp. 83-86
-
-
Ruby, J.G.1
Jan, C.H.2
Bartel, D.P.3
-
26
-
-
34447107760
-
The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila
-
Okamura K, Hagen JW, Duan H, Tyler DM, Lai EC. The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila. Cell 2007;130:89-100.
-
(2007)
Cell
, vol.130
, pp. 89-100
-
-
Okamura, K.1
Hagen, J.W.2
Duan, H.3
Tyler, D.M.4
Lai, E.C.5
-
27
-
-
0347361541
-
Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
-
Yi R, Qin Y, Macara IG, Cullen BR. Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev 2003;17:3011- 3016.
-
(2003)
Genes Dev
, vol.17
, pp. 3011-3016
-
-
Yi, R.1
Qin, Y.2
Macara, I.G.3
Cullen, B.R.4
-
28
-
-
0347988235
-
Nuclear export of microRNA precursors
-
Lund E, Guttinger S, Calado A, Dahlberg JE, Kutay U. Nuclear export of microRNA precursors. Science 2004;303:95-98.
-
(2004)
Science
, vol.303
, pp. 95-98
-
-
Lund, E.1
Guttinger, S.2
Calado, A.3
Dahlberg, J.E.4
Kutay, U.5
-
29
-
-
0037458712
-
Exportin-5 mediates nuclear export of minihelix-containing RNAs
-
Gwizdek C, Ossareh-Nazari B, Brownawell AM, Doglio A, Bertrand E, Macara IG et al. Exportin-5 mediates nuclear export of minihelix-containing RNAs. J Biol Chem 2003;278:5505-5508.
-
(2003)
J Biol Chem
, vol.278
, pp. 5505-5508
-
-
Gwizdek, C.1
Ossareh-Nazari, B.2
Brownawell, A.M.3
Doglio, A.4
Bertrand, E.5
Macara, I.G.6
-
30
-
-
0035800521
-
A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA
-
Hutvagner G, McLachlan J, Pasquinelli AE, Balint E, Tuschl T, Zamore PD. A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science 2001;293:834-838.
-
(2001)
Science
, vol.293
, pp. 834-838
-
-
Hutvagner, G.1
McLachlan, J.2
Pasquinelli, A.E.3
Balint, E.4
Tuschl, T.5
Zamore, P.D.6
-
31
-
-
3142729150
-
Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways
-
Okamura K, Ishizuka A, Siomi H, Siomi MC. Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways. Genes Dev 2004;18:1655-1666.
-
(2004)
Genes Dev
, vol.18
, pp. 1655-1666
-
-
Okamura, K.1
Ishizuka, A.2
Siomi, H.3
Siomi, M.C.4
-
32
-
-
10744225153
-
Asymmetry in the assembly of the RNAi enzyme complex
-
Schwarz DS, Hutvagner G, Du T, Xu Z, Aronin N, Zamore PD. Asymmetry in the assembly of the RNAi enzyme complex. Cell 2003;115:199-208.
-
(2003)
Cell
, vol.115
, pp. 199-208
-
-
Schwarz, D.S.1
Hutvagner, G.2
Du, T.3
Xu, Z.4
Aronin, N.5
Zamore, P.D.6
-
33
-
-
38649111931
-
In vitro reconstitution of the human RISC-loading complex
-
MacRae IJ, Ma E, Zhou M, Robinson CV, Doudna JA. In vitro reconstitution of the human RISC-loading complex. Proc Natl Acad Sci USA 2008;105:512-517.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 512-517
-
-
MacRae, I.J.1
Ma, E.2
Zhou, M.3
Robinson, C.V.4
Doudna, J.A.5
-
34
-
-
34247364093
-
Mechanisms of microRNA-mediated gene regulation in animal cells
-
Nilsen TW. Mechanisms of microRNA-mediated gene regulation in animal cells. Trends Genet 2007;23:243-249.
-
(2007)
Trends Genet
, vol.23
, pp. 243-249
-
-
Nilsen, T.W.1
-
35
-
-
34347335707
-
P-body formation is a consequence, not the cause, of RNA-mediated gene silencing
-
Eulalio A, Behm-Ansmant I, Schweizer D, Izaurralde E. P-body formation is a consequence, not the cause, of RNA-mediated gene silencing. Mol Cell Biol 2007;27:3970-3981.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 3970-3981
-
-
Eulalio, A.1
Behm-Ansmant, I.2
Schweizer, D.3
Izaurralde, E.4
-
36
-
-
34547441263
-
Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5′-UTR as in the 3′-UTR
-
Lytle JR, Yario TA, Steitz JA. Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5′-UTR as in the 3′-UTR. Proc Natl Acad Sci USA 2007;104:9667-9672.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 9667-9672
-
-
Lytle, J.R.1
Yario, T.A.2
Steitz, J.A.3
-
37
-
-
36749026906
-
Switching from repression to activation: MicroRNAs can up-regulate translation
-
Vasudevan S, Tong Y, Steitz JA. Switching from repression to activation: microRNAs can up-regulate translation. Science 2007;318:1931-1934.
-
(2007)
Science
, vol.318
, pp. 1931-1934
-
-
Vasudevan, S.1
Tong, Y.2
Steitz, J.A.3
-
38
-
-
33846699083
-
A hexanucleotide element directs microRNA nuclear import
-
Hwang HW, Wentzel EA, Mendell JT. A hexanucleotide element directs microRNA nuclear import. Science 2007;315:97-100.
-
(2007)
Science
, vol.315
, pp. 97-100
-
-
Hwang, H.W.1
Wentzel, E.A.2
Mendell, J.T.3
-
39
-
-
34548230885
-
Ultraconserved regions encoding ncRNAs are altered in human leukemias and carcinomas
-
Calin GA, Liu CG, Ferracin M, Hyslop T, Spizzo R, Sevignani C et al. Ultraconserved regions encoding ncRNAs are altered in human leukemias and carcinomas. Cancer Cell 2007;12:215-229.
-
(2007)
Cancer Cell
, vol.12
, pp. 215-229
-
-
Calin, G.A.1
Liu, C.G.2
Ferracin, M.3
Hyslop, T.4
Spizzo, R.5
Sevignani, C.6
-
40
-
-
38049155825
-
Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA
-
Yu W, Gius D, Onyango P, Muldoon-Jacobs K, Karp J, Feinberg AP et al. Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA. Nature 2008;451:202-206.
-
(2008)
Nature
, vol.451
, pp. 202-206
-
-
Yu, W.1
Gius, D.2
Onyango, P.3
Muldoon-Jacobs, K.4
Karp, J.5
Feinberg, A.P.6
-
41
-
-
18244385475
-
MicroRNAs regulate brain morphogenesis in zebrafish
-
Giraldez AJ, Cinalli RM, Glasner ME, Enright AJ, Thomson JM, Baskerville S et al. MicroRNAs regulate brain morphogenesis in zebrafish. Science 2005;308:833-838.
-
(2005)
Science
, vol.308
, pp. 833-838
-
-
Giraldez, A.J.1
Cinalli, R.M.2
Glasner, M.E.3
Enright, A.J.4
Thomson, J.M.5
Baskerville, S.6
-
44
-
-
34047234690
-
Characterization and identification of microRNA core promoters in four model species
-
Zhou X, Ruan J, Wang G, Zhang W. Characterization and identification of microRNA core promoters in four model species. PLoS Comput Biol 2007;3:e37.
-
(2007)
PLoS Comput Biol
, vol.3
-
-
Zhou, X.1
Ruan, J.2
Wang, G.3
Zhang, W.4
-
45
-
-
33847065486
-
The epigenomics of cancer
-
Jones PA, Baylin SB. The epigenomics of cancer. Cell 2007;128:683-692.
-
(2007)
Cell
, vol.128
, pp. 683-692
-
-
Jones, P.A.1
Baylin, S.B.2
-
46
-
-
0037372003
-
Epigenetic regulation of gene expression: How the genome integrates intrinsic and environmental signals
-
Jaenisch R, Bird A. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat Genet 2003;33(Suppl.):245-254.
-
(2003)
Nat Genet
, vol.33
, Issue.SUPPL.
, pp. 245-254
-
-
Jaenisch, R.1
Bird, A.2
-
47
-
-
33744805399
-
Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells
-
Saito Y, Liang G, Egger G, Friedman JM, Chuang JC, Coetzee GA et al. Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells. Cancer Cell 2006;9:435-443.
-
(2006)
Cancer Cell
, vol.9
, pp. 435-443
-
-
Saito, Y.1
Liang, G.2
Egger, G.3
Friedman, J.M.4
Chuang, J.C.5
Coetzee, G.A.6
-
48
-
-
38349191617
-
CpG island hypermethylation of tumor suppressor microRNAs in human cancer
-
Lujambio A, Esteller M. CpG island hypermethylation of tumor suppressor microRNAs in human cancer. Cell Cycle 2007;6:1455-1459.
-
(2007)
Cell Cycle
, vol.6
, pp. 1455-1459
-
-
Lujambio, A.1
Esteller, M.2
-
49
-
-
33847748913
-
The human let-7a-3 locus contains an epigenetically regulated microRNA gene with oncogenic function
-
Brueckner B, Stresemann C, Kuner R, Mund C, Musch T, Meister M et al. The human let-7a-3 locus contains an epigenetically regulated microRNA gene with oncogenic function. Cancer Res 2007;67:1419-1423.
-
(2007)
Cancer Res
, vol.67
, pp. 1419-1423
-
-
Brueckner, B.1
Stresemann, C.2
Kuner, R.3
Mund, C.4
Musch, T.5
Meister, M.6
-
50
-
-
35748979703
-
Epigenetic silencing of the myelopoiesis regulator microRNA-223 by the AML1/ETO oncoprotein
-
Fazi F, Racanicchi S, Zardo G, Starnes LM, Mancini M, Travaglini L et al. Epigenetic silencing of the myelopoiesis regulator microRNA-223 by the AML1/ETO oncoprotein. Cancer Cell 2007;12:457-466.
-
(2007)
Cancer Cell
, vol.12
, pp. 457-466
-
-
Fazi, F.1
Racanicchi, S.2
Zardo, G.3
Starnes, L.M.4
Mancini, M.5
Travaglini, L.6
-
51
-
-
0242266620
-
Dicer is essential for mouse development
-
Bernstein E, Kim SY, Carmell MA, Murchison EP, Alcorn H, Li MZ et al. Dicer is essential for mouse development. Nat Genet 2003;35:215-217.
-
(2003)
Nat Genet
, vol.35
, pp. 215-217
-
-
Bernstein, E.1
Kim, S.Y.2
Carmell, M.A.3
Murchison, E.P.4
Alcorn, H.5
Li, M.Z.6
-
52
-
-
33144457798
-
Dicer function is essential for lung epithelium morphogenesis
-
Harris KS, Zhang Z, McManus MT, Harfe BD, Sun X. Dicer function is essential for lung epithelium morphogenesis. Proc Natl Acad Sci USA 2006;103:2208-2213.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 2208-2213
-
-
Harris, K.S.1
Zhang, Z.2
McManus, M.T.3
Harfe, B.D.4
Sun, X.5
-
53
-
-
23344439006
-
The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb
-
Harfe BD, McManus MT, Mansfield JH, Hornstein E, Tabin CJ. The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb. Proc Natl Acad Sci USA 2005;102:10898-10903.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 10898-10903
-
-
Harfe, B.D.1
McManus, M.T.2
Mansfield, J.H.3
Hornstein, E.4
Tabin, C.J.5
-
54
-
-
33646716847
-
The miRNA-processing enzyme dicer is essential for the morphogenesis and maintenance of hair follicles
-
Andl T, Murchison EP, Liu F, Zhang Y, Yunta-Gonzalez M, Tobias JW et al. The miRNA-processing enzyme dicer is essential for the morphogenesis and maintenance of hair follicles. Curr Biol 2006;16:1041-1049.
-
(2006)
Curr Biol
, vol.16
, pp. 1041-1049
-
-
Andl, T.1
Murchison, E.P.2
Liu, F.3
Zhang, Y.4
Yunta-Gonzalez, M.5
Tobias, J.W.6
-
55
-
-
35748958766
-
Essential role for Dicer during skeletal muscle development
-
O'Rourke JR, Georges SA, Seay HR, Tapscott SJ, McManus MT, Goldhamer DJ et al. Essential role for Dicer during skeletal muscle development. Dev Biol 2007;311:359-368.
-
(2007)
Dev Biol
, vol.311
, pp. 359-368
-
-
O'Rourke, J.R.1
Georges, S.A.2
Seay, H.R.3
Tapscott, S.J.4
McManus, M.T.5
Goldhamer, D.J.6
-
56
-
-
25144525014
-
Core transcriptional regulatory circuitry in human embryonic stem cells
-
Boyer LA, Lee TI, Cole MF, Johnstone SE, Levine SS, Zucker JP et al. Core transcriptional regulatory circuitry in human embryonic stem cells. Cell 2005;122:947-956.
-
(2005)
Cell
, vol.122
, pp. 947-956
-
-
Boyer, L.A.1
Lee, T.I.2
Cole, M.F.3
Johnstone, S.E.4
Levine, S.S.5
Zucker, J.P.6
-
57
-
-
0037227099
-
Multipotent cell lineages in early mouse development depend on SOX2 function
-
Avilion AA, Nicolis SK, Pevny LH, Perez L, Vivian N, Lovell-Badge R. Multipotent cell lineages in early mouse development depend on SOX2 function. Genes Dev 2003;17:126-140.
-
(2003)
Genes Dev
, vol.17
, pp. 126-140
-
-
Avilion, A.A.1
Nicolis, S.K.2
Pevny, L.H.3
Perez, L.4
Vivian, N.5
Lovell-Badge, R.6
-
58
-
-
0038143611
-
Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells
-
Chambers I, Colby D, Robertson M, Nichols J, Lee S, Tweedie S et al. Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. Cell 2003;113:643-655.
-
(2003)
Cell
, vol.113
, pp. 643-655
-
-
Chambers, I.1
Colby, D.2
Robertson, M.3
Nichols, J.4
Lee, S.5
Tweedie, S.6
-
59
-
-
0032582513
-
Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4
-
Nichols J, Zevnik B, Anastassiadis K, Niwa H, Klewe-Nebenius D, Chambers I et al. Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4. Cell 1998;95:379- 391.
-
(1998)
Cell
, vol.95
, pp. 379-391
-
-
Nichols, J.1
Zevnik, B.2
Anastassiadis, K.3
Niwa, H.4
Klewe-Nebenius, D.5
Chambers, I.6
-
60
-
-
38349064711
-
MicroRNA-134 modulates the differentiation of mouse embryonic stem cells where it causes post-transcriptional attenuation of Nanog and LRH1
-
Tay YM, Tam WL, Ang YS, Gaughwin PM, Yang HH, Wang W et al. MicroRNA-134 modulates the differentiation of mouse embryonic stem cells where it causes post-transcriptional attenuation of Nanog and LRH1. Stem Cells 2007;26:17-29.
-
(2007)
Stem Cells
, vol.26
, pp. 17-29
-
-
Tay, Y.M.1
Tam, W.L.2
Ang, Y.S.3
Gaughwin, P.M.4
Yang, H.H.5
Wang, W.6
-
61
-
-
43449100341
-
REST maintains self-renewal and pluripotency of embryonic stem cells
-
Singh SK, Kagalwala MN, Parker-Thornburg J, Adams H, Majumder S. REST maintains self-renewal and pluripotency of embryonic stem cells. Nature 2008;453:223-227.
-
(2008)
Nature
, vol.453
, pp. 223-227
-
-
Singh, S.K.1
Kagalwala, M.N.2
Parker-Thornburg, J.3
Adams, H.4
Majumder, S.5
-
62
-
-
0029841389
-
Combinatorial control of muscle development by basic helix-loop-helix and MADS-box transcription factors
-
Molkentin JD, Olson EN. Combinatorial control of muscle development by basic helix-loop-helix and MADS-box transcription factors. Proc Natl Acad Sci USA 1996;93:9366-9373.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 9366-9373
-
-
Molkentin, J.D.1
Olson, E.N.2
-
63
-
-
38049147787
-
MEF2: A central regulator of diverse developmental programs
-
Potthoff MJ, Olson EN. MEF2: a central regulator of diverse developmental programs. Development 2007;134:4131-4140.
-
(2007)
Development
, vol.134
, pp. 4131-4140
-
-
Potthoff, M.J.1
Olson, E.N.2
-
64
-
-
22444437609
-
Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis
-
Zhao Y, Samal E, Srivastava D. Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis. Nature 2005;436:214-220.
-
(2005)
Nature
, vol.436
, pp. 214-220
-
-
Zhao, Y.1
Samal, E.2
Srivastava, D.3
-
65
-
-
31744432337
-
The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation
-
Chen JF, Mandel EM, Thomson JM, Wu Q, Callis TE, Hammond SM et al. The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation. Nat Genet 2006;38:228-233.
-
(2006)
Nat Genet
, vol.38
, pp. 228-233
-
-
Chen, J.F.1
Mandel, E.M.2
Thomson, J.M.3
Wu, Q.4
Callis, T.E.5
Hammond, S.M.6
-
66
-
-
33745032991
-
Myogenic factors that regulate expression of muscle-specific microRNAs
-
Rao PK, Kumar RM, Farkhondeh M, Baskerville S, Lodish HF. Myogenic factors that regulate expression of muscle-specific microRNAs. Proc Natl Acad Sci USA 2006;103:8721-8726.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 8721-8726
-
-
Rao, P.K.1
Kumar, R.M.2
Farkhondeh, M.3
Baskerville, S.4
Lodish, H.F.5
-
67
-
-
38049156025
-
An intragenic MEF2-dependent enhancer directs muscle-specific expression of microRNAs 1 and 133
-
Liu N, Williams AH, Kim Y, McAnally J, Bezprozvannaya S, Sutherland LB et al. An intragenic MEF2-dependent enhancer directs muscle-specific expression of microRNAs 1 and 133. Proc Natl Acad Sci USA 2007;104:20844-20849.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 20844-20849
-
-
Liu, N.1
Williams, A.H.2
Kim, Y.3
McAnally, J.4
Bezprozvannaya, S.5
Sutherland, L.B.6
-
68
-
-
30044437240
-
MicroRNA1 influences cardiac differentiation in Drosophila and regulates notch signaling
-
Kwon C, Han Z, Olson EN, Srivastava D. MicroRNA1 influences cardiac differentiation in Drosophila and regulates notch signaling. Proc Natl Acad Sci USA 2005;102:18986-18991.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 18986-18991
-
-
Kwon, C.1
Han, Z.2
Olson, E.N.3
Srivastava, D.4
-
69
-
-
32544457732
-
Global and gene-specific analyses show distinct roles for Myod and Myog at a common set of promoters
-
Cao Y, Kumar RM, Penn BH, Berkes CA, Kooperberg C, Boyer LA et al. Global and gene-specific analyses show distinct roles for Myod and Myog at a common set of promoters. EMBO J 2006;25:502-511.
-
(2006)
EMBO J
, vol.25
, pp. 502-511
-
-
Cao, Y.1
Kumar, R.M.2
Penn, B.H.3
Berkes, C.A.4
Kooperberg, C.5
Boyer, L.A.6
-
70
-
-
33749557894
-
MyoD inhibits Fstl1 and Utrn expression by inducing transcription of miR-206
-
Rosenberg MI, Georges SA, Asawachaicharn A, Analau E, Tapscott SJ. MyoD inhibits Fstl1 and Utrn expression by inducing transcription of miR-206. J Cell Biol 2006;175:77-85.
-
(2006)
J Cell Biol
, vol.175
, pp. 77-85
-
-
Rosenberg, M.I.1
Georges, S.A.2
Asawachaicharn, A.3
Analau, E.4
Tapscott, S.J.5
-
71
-
-
33748102321
-
Muscle-specific microRNA miR-206 promotes muscle differentiation
-
Kim HK, Lee YS, Sivaprasad U, Malhotra A, Dutta A. Muscle-specific microRNA miR-206 promotes muscle differentiation. J Cell Biol 2006;174:677-687.
-
(2006)
J Cell Biol
, vol.174
, pp. 677-687
-
-
Kim, H.K.1
Lee, Y.S.2
Sivaprasad, U.3
Malhotra, A.4
Dutta, A.5
-
72
-
-
34249279050
-
MicroRNA-133 controls cardiac hypertrophy
-
Care A, Catalucci D, Felicetti F, Bonci D, Addario A, Gallo P et al. MicroRNA-133 controls cardiac hypertrophy. Nat Med 2007;13:613-618.
-
(2007)
Nat Med
, vol.13
, pp. 613-618
-
-
Care, A.1
Catalucci, D.2
Felicetti, F.3
Bonci, D.4
Addario, A.5
Gallo, P.6
-
73
-
-
33847038668
-
MicroRNAs play an essential role in the development of cardiac hypertrophy
-
Sayed D, Hong C, Chen IY, Lypowy J, Abdellatif M. MicroRNAs play an essential role in the development of cardiac hypertrophy. Circ Res 2007;100:416-424.
-
(2007)
Circ Res
, vol.100
, pp. 416-424
-
-
Sayed, D.1
Hong, C.2
Chen, I.Y.3
Lypowy, J.4
Abdellatif, M.5
-
74
-
-
33845317603
-
A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure
-
van Rooij E, Sutherland LB, Liu N, Williams AH, McAnally J, Gerard RD et al. A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure. Proc Natl Acad Sci USA 2006;103:18255-18260.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 18255-18260
-
-
van Rooij, E.1
Sutherland, L.B.2
Liu, N.3
Williams, A.H.4
McAnally, J.5
Gerard, R.D.6
-
75
-
-
34247589595
-
Control of stress-dependent cardiac growth and gene expression by a microRNA
-
van Rooij E, Sutherland LB, Qi X, Richardson JA, Hill J, Olson EN. Control of stress-dependent cardiac growth and gene expression by a microRNA. Science 2007;316:575-579.
-
(2007)
Science
, vol.316
, pp. 575-579
-
-
van Rooij, E.1
Sutherland, L.B.2
Qi, X.3
Richardson, J.A.4
Hill, J.5
Olson, E.N.6
-
76
-
-
0347357618
-
A microRNA controlling left/right neuronal asymmetry in Caenorhabditis elegans
-
Johnston RJ, Hobert O. A microRNA controlling left/right neuronal asymmetry in Caenorhabditis elegans. Nature 2003;426:845-849.
-
(2003)
Nature
, vol.426
, pp. 845-849
-
-
Johnston, R.J.1
Hobert, O.2
-
77
-
-
18444415448
-
Regulation of miRNA expression during neural cell specification
-
Smirnova L, Grafe A, Seiler A, Schumacher S, Nitsch R, Wulczyn FG. Regulation of miRNA expression during neural cell specification. Eur J Neurosci 2005;21:1469-1477.
-
(2005)
Eur J Neurosci
, vol.21
, pp. 1469-1477
-
-
Smirnova, L.1
Grafe, A.2
Seiler, A.3
Schumacher, S.4
Nitsch, R.5
Wulczyn, F.G.6
-
78
-
-
34548537573
-
A MicroRNA feedback circuit in midbrain dopamine neurons
-
Kim J, Inoue K, Ishii J, Vanti WB, Voronov SV, Murchison E et al. A MicroRNA feedback circuit in midbrain dopamine neurons. Science 2007;317:1220-1224.
-
(2007)
Science
, vol.317
, pp. 1220-1224
-
-
Kim, J.1
Inoue, K.2
Ishii, J.3
Vanti, W.B.4
Voronov, S.V.5
Murchison, E.6
-
79
-
-
28044439909
-
A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis
-
Vo N, Klein ME, Varlamova O, Keller DM, Yamamoto T, Goodman RH et al. A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis. Proc Natl Acad Sci USA 2005;102:16426- 16431.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 16426-16431
-
-
Vo, N.1
Klein, M.E.2
Varlamova, O.3
Keller, D.M.4
Yamamoto, T.5
Goodman, R.H.6
-
80
-
-
33750432857
-
Comparative sequence analysis reveals an intricate network among REST, CREB and miRNA in mediating neuronal gene expression
-
Wu J, Xie X. Comparative sequence analysis reveals an intricate network among REST, CREB and miRNA in mediating neuronal gene expression. Genome Biol 2006;7:R85.
-
(2006)
Genome Biol
, vol.7
-
-
Wu, J.1
Xie, X.2
-
81
-
-
36448969801
-
Homeostatic regulation of MeCP2 expression by a CREB-induced microRNA
-
Klein ME, Lioy DT, Ma L, Impey S, Mandel G, Goodman RH. Homeostatic regulation of MeCP2 expression by a CREB-induced microRNA. Nat Neurosci 2007;10:1513-1514.
-
(2007)
Nat Neurosci
, vol.10
, pp. 1513-1514
-
-
Klein, M.E.1
Lioy, D.T.2
Ma, L.3
Impey, S.4
Mandel, G.5
Goodman, R.H.6
-
82
-
-
0028934541
-
REST: A mammalian silencer protein that restricts sodium channel gene expression to neurons
-
Chong JA, Tapia-Ramirez J, Kim S, Toledo-Aral JJ, Zheng Y, Boutros MC et al. REST: a mammalian silencer protein that restricts sodium channel gene expression to neurons. Cell 1995;80:949-957.
-
(1995)
Cell
, vol.80
, pp. 949-957
-
-
Chong, J.A.1
Tapia-Ramirez, J.2
Kim, S.3
Toledo-Aral, J.J.4
Zheng, Y.5
Boutros, M.C.6
-
83
-
-
33144481470
-
Reciprocal actions of REST and a microRNA promote neuronal identity
-
Conaco C, Otto S, Han JJ, Mandel G. Reciprocal actions of REST and a microRNA promote neuronal identity. Proc Natl Acad Sci USA 2006;103:2422-2427.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 2422-2427
-
-
Conaco, C.1
Otto, S.2
Han, J.J.3
Mandel, G.4
-
84
-
-
0037315894
-
Disruption of differentiation in human cancer: AML shows the way
-
Tenen DG. Disruption of differentiation in human cancer: AML shows the way. Nat Rev Cancer 2003;3:89-101.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 89-101
-
-
Tenen, D.G.1
-
85
-
-
0346727524
-
MicroRNAs modulate hematopoietic lineage differentiation
-
Chen C-Z, Li L, Lodish HF, Bartell DP. MicroRNAs modulate hematopoietic lineage differentiation. Science 2004;303:83-86.
-
(2004)
Science
, vol.303
, pp. 83-86
-
-
Chen, C.-Z.1
Li, L.2
Lodish, H.F.3
Bartell, D.P.4
-
86
-
-
20444460289
-
MicroRNA expression profiles classify human cancers
-
Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, Peck D et al. MicroRNA expression profiles classify human cancers. Nature 2005;435:834-838.
-
(2005)
Nature
, vol.435
, pp. 834-838
-
-
Lu, J.1
Getz, G.2
Miska, E.A.3
Alvarez-Saavedra, E.4
Lamb, J.5
Peck, D.6
-
87
-
-
34250877841
-
A mammalian microRNA expression atlas based on small RNA library sequencing
-
Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A et al. A mammalian microRNA expression atlas based on small RNA library sequencing. Cell 2007;129:1401-1414.
-
(2007)
Cell
, vol.129
, pp. 1401-1414
-
-
Landgraf, P.1
Rusu, M.2
Sheridan, R.3
Sewer, A.4
Iovino, N.5
Aravin, A.6
-
88
-
-
29144440077
-
MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation
-
Felli N, Fontana L, Pelosi E, Botta R, Bonci D, Facchiano F et al. MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation. Proc Natl Acad Sci USA 2005;102:18081-18086.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 18081-18086
-
-
Felli, N.1
Fontana, L.2
Pelosi, E.3
Botta, R.4
Bonci, D.5
Facchiano, F.6
-
89
-
-
34347383305
-
MicroRNAs 17-5p-20a-106a control monocytopoiesis through AML1 targeting and M-CSF receptor upregulation
-
Fontana L, Pelosi E, Greco P, Racanicchi S, Testa U, Liuzzi F et al. MicroRNAs 17-5p-20a-106a control monocytopoiesis through AML1 targeting and M-CSF receptor upregulation. Nat Cell Biol 2007;9:775-787.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 775-787
-
-
Fontana, L.1
Pelosi, E.2
Greco, P.3
Racanicchi, S.4
Testa, U.5
Liuzzi, F.6
-
90
-
-
28344438648
-
A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis
-
Fazi F, Rosa A, Fatica A, Gelmetti V, De Marchis ML, Nervi C et al. A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis. Cell 2005;123:819-831.
-
(2005)
Cell
, vol.123
, pp. 819-831
-
-
Fazi, F.1
Rosa, A.2
Fatica, A.3
Gelmetti, V.4
De Marchis, M.L.5
Nervi, C.6
-
91
-
-
0034673970
-
Roles of the NF1/CTF gene family in transcription and development
-
Gronostajski RM. Roles of the NF1/CTF gene family in transcription and development. Gene 2000;249:31-45.
-
(2000)
Gene
, vol.249
, pp. 31-45
-
-
Gronostajski, R.M.1
-
92
-
-
0031835661
-
CCAAT/enhancer binding protein alpha is a regulatory switch sufficient for induction of granulocytic development from bipotential myeloid progenitors
-
Radomska HS, Huettner CS, Zhang P, Cheng T, Scadden DT, Tenen DG. CCAAT/enhancer binding protein alpha is a regulatory switch sufficient for induction of granulocytic development from bipotential myeloid progenitors. Mol Cell Biol 1998;18:4301-4314.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 4301-4314
-
-
Radomska, H.S.1
Huettner, C.S.2
Zhang, P.3
Cheng, T.4
Scadden, D.T.5
Tenen, D.G.6
-
93
-
-
38049146022
-
The interplay between the master transcription factor PU.1 and miR-424 regulates human monocyte/macrophage differentiation
-
Rosa A, Ballarino M, Sorrentino A, Sthandier O, De Angelis FG, Marchioni M et al. The interplay between the master transcription factor PU.1 and miR-424 regulates human monocyte/macrophage differentiation. Proc Natl Acad Sci USA 2007;104:19849-19854.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 19849-19854
-
-
Rosa, A.1
Ballarino, M.2
Sorrentino, A.3
Sthandier, O.4
De Angelis, F.G.5
Marchioni, M.6
-
94
-
-
20444467290
-
A microRNA polycistron as a potential human oncogene
-
He L, Thomson JM, Hemann MT, Hernando-Monge E, Mu D, Goodson S et al. A microRNA polycistron as a potential human oncogene. Nature 2005;435:828-833.
-
(2005)
Nature
, vol.435
, pp. 828-833
-
-
He, L.1
Thomson, J.M.2
Hemann, M.T.3
Hernando-Monge, E.4
Mu, D.5
Goodson, S.6
-
95
-
-
20444479428
-
c-Myc-regulated microRNAs modulate E2F1 expression
-
O'donnell KA, Wentzel EA, Zeller KI, Dang CV, Mendell JT. c-Myc-regulated microRNAs modulate E2F1 expression. Nature 2005;435:839-843.
-
(2005)
Nature
, vol.435
, pp. 839-843
-
-
O'donnell, K.A.1
Wentzel, E.A.2
Zeller, K.I.3
Dang, C.V.4
Mendell, J.T.5
-
96
-
-
37549008310
-
Widespread microRNA repression by Myc contributes to tumorigenesis
-
Chang TC, Yu D, Lee YS, Wentzel EA, Arking DE, West KM et al. Widespread microRNA repression by Myc contributes to tumorigenesis. Nat Genet 2008;40:43-50.
-
(2008)
Nat Genet
, vol.40
, pp. 43-50
-
-
Chang, T.C.1
Yu, D.2
Lee, Y.S.3
Wentzel, E.A.4
Arking, D.E.5
West, K.M.6
-
97
-
-
0030995824
-
Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F
-
Leone G, DeGregori J, Sears R, Jakoi L, Nevins JR. Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F. Nature 1997;387:422-426.
-
(1997)
Nature
, vol.387
, pp. 422-426
-
-
Leone, G.1
DeGregori, J.2
Sears, R.3
Jakoi, L.4
Nevins, J.R.5
-
98
-
-
34548381748
-
Myc'ed messages': Myc induces transcription of E2F1 while inhibiting its translation via a microRNA polycistron
-
Coller HA, Forman JJ, Legesse-Miller A. 'Myc'ed messages': Myc induces transcription of E2F1 while inhibiting its translation via a microRNA polycistron. PLoS Genet 2007;3:e146.
-
(2007)
PLoS Genet
, vol.3
-
-
Coller, H.A.1
Forman, J.J.2
Legesse-Miller, A.3
-
99
-
-
34047264639
-
Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors
-
Woods K, Thomson JM, Hammond SM. Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors. J Biol Chem 2007;282:2130-2134.
-
(2007)
J Biol Chem
, vol.282
, pp. 2130-2134
-
-
Woods, K.1
Thomson, J.M.2
Hammond, S.M.3
-
100
-
-
34047267329
-
-
Sylvestre Y, De G V, Querido E, Mukhopadhyay UK, Bourdeau V, Major F et al. An E2F/miR-20a autoregulatory feedback loop. J Biol Chem 2007;282:2135-2143.
-
Sylvestre Y, De G V, Querido E, Mukhopadhyay UK, Bourdeau V, Major F et al. An E2F/miR-20a autoregulatory feedback loop. J Biol Chem 2007;282:2135-2143.
-
-
-
-
101
-
-
39849096995
-
Regulation of progenitor cell proliferation and granulocyte function by microRNA-223
-
Johnnidis JB, Harris MH, Wheeler RT, Stehling-Sun S, Lam MH, Kirak O et al. Regulation of progenitor cell proliferation and granulocyte function by microRNA-223. Nature 2008;451:1125-1129.
-
(2008)
Nature
, vol.451
, pp. 1125-1129
-
-
Johnnidis, J.B.1
Harris, M.H.2
Wheeler, R.T.3
Stehling-Sun, S.4
Lam, M.H.5
Kirak, O.6
-
102
-
-
33846190181
-
Tcl1 expression in chronic lymphocytic leukemia is regulated by miR-29 and miR-181
-
Pekarsky Y, Santanam U, Cimmino A, Palamarchuk A, Efanov A, Maximov V et al. Tcl1 expression in chronic lymphocytic leukemia is regulated by miR-29 and miR-181. Cancer Res 2006;66:11590-11593.
-
(2006)
Cancer Res
, vol.66
, pp. 11590-11593
-
-
Pekarsky, Y.1
Santanam, U.2
Cimmino, A.3
Palamarchuk, A.4
Efanov, A.5
Maximov, V.6
|