Rapid transcriptional activity in vivo and slow DNA binding in vitro by an artificial multi-zinc finger protein

Biochemistry

Volumn 47, Issue 38, 2008, Pages 10171-10177

  Morisaki, Tatsuya ^a   Imanishi, Miki ^a,b   Futaki, Shiroh ^a   Sugiura, Yukio ^c  

^a KYOTO UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c KYOTO WOMEN'S UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING SITES; DNA; DNA SEQUENCES; GENES; NUCLEIC ACIDS; ORGANIC ACIDS; PROTEINS; TRANSCRIPTION FACTORS; ZINC;

ARTIFICIAL GENE; ARTIFICIAL TRANSCRIPTION FACTORS; DNA BINDING DOMAINS; DNA-BINDING; GENE PROMOTERS; IN-VITRO; IN-VIVO; MULTIMERIZATION; REPORTER GENES; SINGLE SITES; TARGET SEQUENCES; TRANSCRIPTIONAL ACTIVATIONS; TRANSCRIPTIONAL ACTIVITIES; ZINC FINGER PROTEINS; ZINC FINGERS;

TRANSCRIPTION;

DNA FRAGMENT; KRUPPEL LIKE FACTOR 6; TRANSCRIPTION FACTOR IIIA; ZINC FINGER PROTEIN;

ARTICLE; CHROMATOGRAPHY; DNA BINDING MOTIF; DNA SEQUENCE; GEL MOBILITY SHIFT ASSAY; GENE CONTROL; GENE TARGETING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN DNA BINDING; REPORTER GENE; SEQUENCE ANALYSIS; TRANSCRIPTION INITIATION;

ANIMALS; BINDING SITES; DNA-BINDING PROTEINS; GENE TARGETING; GENES, SYNTHETIC; KINETICS; LIGANDS; MICE; TIME FACTORS; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; ZINC FINGERS;

EID: 52249093066     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi801124b     Document Type: Article

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