AMACR expression in colorectal cancer is associated with left-sided tumor localization

Virchows Archiv

Volumn 453, Issue 3, 2008, Pages 243-248

  Marx, Andreas ^a   Simon, Philipp ^a   Simon, Ronald ^a   Mirlacher, Martina ^a   Izbicki, Jakob R ^a   Yekebas, Emre ^a   Kaifi, Jussuf T ^a   Terracciano, Luigi ^b   Sauter, Guido ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b UNIVERSITY HOSPITAL BASEL   (Switzerland)

Author keywords

AMACR; Colorectal cancer

Indexed keywords

2 METHYLACYL COENZYME A RACEMASE; FATTY ACID;

ARTICLE; CANCER STAGING; COLORECTAL CANCER; COLORECTAL CARCINOMA; FEMALE; FOLLOW UP; HUMAN; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; MUCINOUS CARCINOMA; PHENOTYPE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; TISSUE MICROARRAY; TRANSVERSE COLON; TUMOR LOCALIZATION;

COLORECTAL NEOPLASMS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; PROGNOSIS; RACEMASES AND EPIMERASES; TUMOR MARKERS, BIOLOGICAL;

EID: 51749093542     PISSN: 09456317     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00428-008-0646-1     Document Type: Article

References (30)

1. A Chao MJ Thun CJ Connell ML McCullough EJ Jacobs WD Flanders C Rodriguez R Sinha EE Calle 2005 Meat consumption and risk of colorectal cancer JAMA 293 172 182
2. ZM Chen JH Ritter HL Wang 2005 Differential expression of alpha-methylacyl coenzyme A racemase in adenocarcinomas of the small and large intestines Am J Surg Pathol 29 890 896
3. R Dorer RD Odze 2006 AMACR immunostaining is useful in detecting dysplastic epithelium in Barrett's esophagus, ulcerative colitis, and Crohn's disease Am J Surg Pathol 30 871 877
4. S Ferdinandusse S Denis L Ijlst G Dacremont HR Waterham RJ Wanders 2000 Subcellular localization and physiological role of alpha-methylacyl-CoA racemase J Lipid Res 41 1890 1896
5. S Ferdinandusse H Overmars S Denis HR Waterham RJ Wanders P Vreken 2001 Plasma analysis of di- and trihydroxycholestanoic acid diastereoisomers in peroxisomal alpha-methylacyl-CoA racemase deficiency J Lipid Res 42 137 141
6. O Hameed PA Humphrey 2005 Immunohistochemistry in diagnostic surgical pathology of the prostate Semin Diagn Pathol 22 88 104
7. PA Humphrey 2007 Diagnosis of adenocarcinoma in prostate needle biopsy tissue J Clin Pathol 60 35 42
8. Z Jiang GR Fanger BF Banner BA Woda P Algate K Dresser J Xu SG Reed KL Rock PG Chu 2003 A dietary enzyme: alpha-methylacyl-CoA racemase/P504S is overexpressed in colon carcinoma Cancer Detect Prev 27 422 426
9. Z Jiang GR Fanger BA Woda BF Banner P Algate K Dresser J Xu PG Chu 2003 Expression of alpha-methylacyl-CoA racemase (P504s) in various malignant neoplasms and normal tissues: a study of 761 cases Human Pathol 34 792 796
10. Z Jiang BA Woda KL Rock Y Xu L Savas A Khan G Pihan F Cai JS Babcook P Rathanaswami SG Reed J Xu GR Fanger 2001 P504S: a new molecular marker for the detection of prostate carcinoma Am J Surg Pathol 25 1397 1404
11. SC Larsson J Rafter L Holmberg L Bergkvist A Wolk 2005 Red meat consumption and risk of cancers of the proximal colon, distal colon and rectum: the Swedish Mammography Cohort Int J Cancer 113 829 834
12. SC Larsson A Wolk 2006 Meat consumption and risk of colorectal cancer: a meta-analysis of prospective studies Int J Cancer 119 2657 2664
13. A Lin MR Weiser DS Klimstra PB Paty LH Tang H Al-Ahmadie S Hoo Park JG Guillem L Temple WD Wong WL Gerald J Shia 2007 Differential expression of alpha-methylacyl-coenzyme A racemase in colorectal carcinoma bears clinical and pathologic significance Human Pathol 38 850 856
14. G Martignoni M Brunelli S Gobbo A Remo V Ficarra P Cossu-Rocca M Pea M Chilosi F Menestrina L Cheng 2007 Role of molecular markers in diagnosis and prognosis of renal cell carcinoma Anal Quant Cytol Histol 29 41 49
15. JA Mobley I Leav P Zielie C Wotkowitz J Evans YW Lam BS L'Esperance Z Jiang SM Ho 2003 Branched fatty acids in dairy and beef products markedly enhance alpha-methylacyl-CoA racemase expression in prostate cancer cells in vitro Cancer Epidemiol Biomark Prev 12 775 783
16. V Molinie A Balaton S Rotman D Mansouri I De Pinieux T Homsi L Guillou 2006 Alpha-methyl CoA racemase expression in renal cell carcinomas Human Pathol 37 698 703
17. V Molinie JM Herve PM Lugagne L Yonneau S Ellard T Lebret H Botto 2005 Value of new prostate cancer markers: alpha methylacyl CoA racemase (P504S) and p63 Prog Urol 15 611 615
18. JN Mubiru AJ Valente DA Troyer 2005 A variant of the alpha-methyl-acyl- CoA racemase gene created by a deletion in exon 5 and its expression in prostate cancer Prostate 65 117 123
19. T Narisawa M Takahashi T Masuda M Niwa 1986 Dietary factors to induce and suppress colon cancer development Gan No Rinsho 32 674 679
20. A Nassar MB Amin DG Sexton C Cohen 2005 Utility of alpha-methylacyl coenzyme A racemase (p504s antibody) as a diagnostic immunohistochemical marker for cancer Appl Immunohistochem Mol Morphol 13 252 255
21. MA Rubin TA Bismar O Andren L Mucci R Kim R Shen D Ghosh JT Wei AM Chinnaiyan HO Adami PW Kantoff JE Johansson 2005 Decreased alpha-methylacyl CoA racemase expression in localized prostate cancer is associated with an increased rate of biochemical recurrence and cancer-specific death Cancer Epidemiol Biomark Prev 14 1424 1432
22. W Schmitz C Albers R Fingerhut E Conzelmann 1995 Purification and characterization of an alpha-methylacyl-CoA racemase from human liver Eur J Biochem 231 815 822
23. KD Setchell JE Heubi KE Bove NC O'Connell T Brewsaugh SJ Steinberg A Moser RH Squires Jr 2003 Liver disease caused by failure to racemize trihydroxycholestanoic acid: gene mutation and effect of bile acid therapy Gastroenterology 124 217 232
24. J Shannon E White AL Shattuck JD Potter 1996 Relationship of food groups and water intake to colon cancer risk Cancer Epidemiol Biomark Prev 5 495 502
25. X Shi E Gong X Wu 2007 Alpha-methylacyl-CoA racemase/P504S overexpression in colorectal carcinoma is correlated with tumor differentiation Appl Immunohistochem Mol Morphol 15 175 180
26. R Simon M Mirlacher G Sauter 2005 Tissue microarrays Methods Mol Med 114 257 268
27. PT Went G Sauter M Oberholzer L Bubendorf 2006 Abundant expression of AMACR in many distinct tumour types Pathology 38 426 432
28. AK Witkiewicz S Varambally R Shen R Mehra MS Sabel D Ghosh AM Chinnaiyan MA Rubin CG Kleer 2005 Alpha-methylacyl-CoA racemase protein expression is associated with the degree of differentiation in breast cancer using quantitative image analysis Cancer Epidemiol Biomark Prev 14 1418 1423
29. J Xu JA Stolk X Zhang SJ Silva RL Houghton M Matsumura TS Vedvick KB Leslie R Badaro SG Reed 2000 Identification of differentially expressed genes in human prostate cancer using subtraction and microarray Cancer Res 60 1677 1682
30. M Zhou AM Chinnaiyan CG Kleer PC Lucas MA Rubin 2002 Alpha-Methylacyl-CoA racemase: a novel tumor marker over-expressed in several human cancers and their precursor lesions Am J Surg Pathol 26 926 931