Subcellular localization and physiological role of α-methylacyl-CoA racemase

Journal of Lipid Research

Volumn 41, Issue 11, 2000, Pages 1890-1896

  Ferdinandusse, S ^a   Denis, S ^a   Ijlst, L ^a   Dacremont, G ^a   Waterham, H R ^a   Wanders, R J A ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

(2R,6) dimethylheptanoyl CoA; Branched chain fatty acid oxidation; Stereospecificity

Indexed keywords

ACYL COENZYME A; BILE ACID; CHOLIC ACID; FATTY ACID; RACEMASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ENZYME ACTIVITY; ENZYME DEFICIENCY; ENZYME LOCALIZATION; FATTY ACID OXIDATION; FIBROBLAST; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MITOCHONDRION; NONHUMAN; NUCLEOTIDE SEQUENCE; PEROXISOME; PRIORITY JOURNAL; RAT; STEREOISOMERISM;

ANIMALS; CELL FRACTIONATION; FATTY ACIDS; FIBROBLASTS; HUMANS; LIVER; MALE; MITOCHONDRIA, LIVER; OXIDATION-REDUCTION; PEROXISOMES; RACEMASES AND EPIMERASES; RATS; RATS, WISTAR;

EID: 0033747547     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Peroxisomal disorders: A review
2. Peroxisomal β-oxidation of 2-methyl-branched acyl-CoA esters: Stereospecific recognition of the 2S-methyl compounds by trihydroxycoprostanoyl-CoA oxidase and pristanoyl-CoA oxidase
3. Substrate stereospecificity in oxidation of (25S)-3α,7α,12α-trihydroxy-5β-cholestanoyl-CoA by peroxisomal trihydroxy-5β-cholestanoyl-CoA oxidase
4. Stereochemistry of peroxisomal and mitochondrial β-oxidation of α-methylacyl-CoAs
5. The occurrence of diastereomers of phytanic and pristanic acids and their determination by gas-liquid chromatography
6. Purification and properties of an α-methylacyl-CoA racemase from rat liver
7. Purification and characterization of an α-methylacyl-CoA racemase from human liver
8. 2-Methylacyl racemase: A coupled assay based on the use of pristanoyl-CoA oxidase/peroxidase and reinvestigation of its subcellular distribution in rat and human liver
9. Mutations in the gene encoding peroxisomal α-methylacyl-CoA racemase cause adult-onset sensory motor neuropathy
10. Configuration at C-25 in 3α,7α,12α-trihydroxy-5β-cholestan-26-oic acid isolated from human bile
11. Disorders of mitochondrial fatty acyl-CoA β-oxidation
12. Phytanic acid and pristanic acid are oxidized by sequential peroxisomal and mitochondrial reactions in cultured fibroblasts
13. Molecular cloning and expression of human carnitine octanoyltransferase: Evidence for its role in the peroxisomal β-oxidation of branched-chain fatty acids
14. Human long chain, very long chain and medium chain acyl-CoA dehydrogenases are specific for the S-enantiomer of 2-methylpentadecanoyl-CoA
15. L-Pipecolate oxidase: A distinct peroxisomal enzyme in man
16. 2-Hydroxyphytanic acid oxidase activity in rat and human liver and its deficiency in the Zellweger syndrome
17. Activity of peroxisomal enzymes and intracellular distribution of catalase in Zellweger syndrome
18. Peroxisomal beta-oxidation of palmitoyl-CoA in human liver homogenates and its deficiency in the cerebrohepato-renal (Zellweger) syndrome
19. Bile acids in peroxisomal disorders
20. 2,6-Dimethylheptanoyl-CoA is a specific substrate for long-chain acyl-CoA dehydrogenase (LCAD): Evidence for a major role of LCAD in branched-chain fatty acid oxidation
21. Comparison of the binding affinities of acyl-CoA-binding protein and fatty-acid-binding protein for long-chain acyl-CoA esters
22. Purification and properties of rat liver acyl-CoA dehydrogenases and electron transfer flavoprotein
23. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
24. Mitochondrial and peroxisomal β oxidation of the branched chain fatty acid 2-methylpalmitate in rat liver
25. Divergent sequences in the 5' region of cDNA suggest alternative splicing as a mechanism for the generation of carnitine acetyltransferases with different subcellular localizations
26. Delta3,5-delta2,4-dienoyl-CoA isomerase from rat liver mitochondria. Purification and characterization of a new enzyme involved in the beta-oxidation of unsaturated fatty acids
27. Delta3,5-delta2,4-dicnoyl-CoA isomerase from rat liver. Molecular characterization
28. Cleavage-site motifs in mitochondrial targeting peptides