Vesicular stomatitis virus matrix protein gene enhances the antitumor effects of radiation via induction of apoptosis

Apoptosis

Volumn 13, Issue 10, 2008, Pages 1205-1214

  Du, Xiao Bo ^a,b   Lang, Jin Yi ^c   Xu, Jian Rong ^d   Lu, You ^a   Wen, Yan Jun ^a   Zhao, Ju Mei ^a,e   Diao, Peng ^a,c   Yuan, Zhi Ping ^a   Yao, Bin ^a,b   Fan, Ling Yu ^a   Wang, Guo Qing ^a   Liu, Li ^a,c   Ding, Zhen Yu ^a   Wang, Yong Sheng ^a   Li, Tao ^c   Wang, Rui ^a   Mao, Yun Qiu ^a   Kan, Bin ^a   Wu, Hong Bin ^a   Li, Hong Xia ^a   Yang, Han Suo ^a   Wu, Hong Bo ^a   Wei, Yu Quan ^a   Zhao, Xia ^a   more..

^a SICHUAN UNIVERSITY   (China)

^b MIANYANG CENTRAL HOSPITAL   (China)

^c SICHUAN CANCER HOSPITAL   (China)

^d SICHUAN UNIVERSITY   (China)

^e Yan'an Health School   (China)

Author keywords

Apoptosis; Matrix protein gene; Radiation; Tumor

Indexed keywords

COBALT 60; LIPOSOME; MATRIX PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER RADIOTHERAPY; COBALT THERAPY; COMPLEX FORMATION; CONTROLLED STUDY; FEMALE; IN VITRO STUDY; IN VIVO STUDY; LEWIS CARCINOMA; MOUSE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; VESICULAR STOMATITIS VIRUS;

ANIMALS; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; FATTY ACIDS, MONOUNSATURATED; GAMMA RAYS; GENE THERAPY; LIPOSOMES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; NEOPLASMS; QUATERNARY AMMONIUM COMPOUNDS; TUMOR STEM CELL ASSAY; VIRAL MATRIX PROTEINS;

MUS; VESICULAR STOMATITIS VIRUS;

EID: 51749085556     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-008-0253-2     Document Type: Article

References (44)

1. R Shao D Karunagaran BP Zhou K Li SS Lo J Deng 1997 Inhibition of nuclear factor-B activity is involved in E1A-mediated sensitization of radiation-induced apoptosis J Biol Chem 272 32739 32742 10.1074/jbc.272.52.32739
2. AM Chinnaiyan U Prasad S Shankar DA Hamstra M Shanaiah TL Chenevert 2000 Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy Proc Natl Acad Sci USA 97 1754 1759 10.1073/pnas.030545097
3. A Tenzer D Zingg S Rocha B Hemmings D Fabbro C Glanzmann 2001 The phosphatidylinositide 3-kinase/Akt survival pathway is a target for the anticancer and radiosensitizing agent PKC412, an inhibitor of protein kinase C Cancer Res 61 8203 8210
4. MB Kastan O Onyekwere D Sidransky B Vogelstein RW Craig 1991 Participation of p53 protein in the cellular response to DNA damage Cancer Res 51 6304 6311
5. SW Lowe EM Schmitt SW Smith BA Osborne T Jacks 1993 p53 is required for radiation-induced apoptosis in mouse thymocytes Nature 362 847 849 10.1038/362847a0
6. H Nagasawa CY Li CG Maki AC Imrich JB Little 1995 Relationship between radiation-induced G1 phase arrest and p53 function in human tumor cells Cancer Res 55 1842 1846
7. JA Roth D Nguyen DD Lawrence BL Kemp CH Carrasco DZ Ferson 1996 Retrovirusmediated wild-type p53 gene transfer to tumors of patients with lung cancer Nat Med 2 985 991 10.1038/nm0996-985
8. D Gallardo KE Drazan WH McBride 1996 Adenovirus-based transfer of wild-type p53 gene increases ovarian tumor radiosensitivity Cancer Res 56 4891 4893
9. JH Li SA Lax J Kim H Klamut FF Li 1999 The effects of ionizing radiation and adenoviral p53 therapy in nasopharyngeal carcinoma Int J Radiat Oncol Biol Phys 43 607 616 10.1016/S0360-3016(98)00432-5
10. DF Stojdl B Lichty S Knowles R Marius H Atkins N Sonenberg 2000 Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus Nat Med 6 821 825 10.1038/77558
11. S Balachandran M Porosnic GN Barber 2001 Oncolytic activity of vesicular stomatitis virus is effective against tumors exhibiting aberrant p53, ras, or myc function and involves the induction of apoptosis J Virol 75 3474 3479 10.1128/JVI.75.7.3474-3479.2001
12. K Shinozaki O Ebert C Kournioti YS Tai SL Woo 2004 Oncolysis of multifocal hepatocellular carcinoma in the rat liver by hepatic artery infusion of vesicular stomatitis virus Mol Ther 9 368 376 10.1016/j.ymthe.2003.12.004
13. Q Li YQ Wei YJ Wen Xia Zhao Ling Tian Li Yang 2004 Induction of apoptosis and tumor regression by vesicular stomatitis virus in the presence of gemcitabine in lung cancer Int J Cancer 20 143 149 10.1002/ijc.20276
14. O Ebert K Shinozaki C Kournioti MS Park A Garcia-Sastre SL Woo 2004 Syncytia induction enhances the oncolytic potential of vesicular stomatitis virus in virotherapy for cancer Cancer Res 1 3265 3270 10.1158/0008-5472.CAN-03- 3753
15. O Ebert S Harbaran K Shinozaki SL Woo 2005 Systemic therapy of experimental breast cancer metastases by mutant vesicular stomatitis virus in immune-competent mice Cancer Gene Ther 2 350 358 10.1038/sj.cgt.7700794
16. M Ahmed DS Lyles 1998 Effect of vesicular stomatitis virus matrix protein on transcription directed by host RNA polymerases I, II, and III J Virol 2 8413 8419
17. BL Black DS Lyles 1992 Vesicular stomatitis virus matrix protein inhibits host cell-directed transcription of target genes in vivo J Virol 66 4058 4064
18. BL Black RB Rhodes M McKenzie DS Lyles 1993 The role of vesicular stomatitis virus matrix protein in inhibition of host-directed gene expression is genetically separable from its function in virus assembly J Virol 67 4814 4821
19. MC Ferran JM Lucas-Lenard 1997 The vesicular stomatitis virus matrix protein inhibits transcription from the human beta interferon promoter J Virol 71 371 377
20. X Lin X Chen Y Wei J Zhao L Fan Y Wen 2007 Efficient inhibition of intraperitoneal human ovarian cancer growth and prolonged survival by gene transfer of vesicular stomatitis virus matrix protein in nude mice Gynecol Oncol 104 540 546 10.1016/j.ygyno.2006.09.022
21. H Zhang Y Wen B Mao Q Gong Z Qian Y Wei 2007 Plasmid encoding matrix protein of vesicular stomatitis viruses as an antitumor agent inhibiting rat glioma growth in situ Exp Oncol 29 85 93
22. JM Zhao T Liu JR Xu GQ Wang XB Du YJ Wen 2007 Effects of vesicular stomatitis virus matrix protein on proliferation and apoptosis of mouse LL/2c cells Ai Zheng 26 230 235
23. Y-Q Wei X Zhao Y Kariya H Fukata K Teshigawara A Uchida 1994 Induction of apoptosis by quercetin: involvement of heat shock protein Cancer Res 54 4952 4957
24. JT Nguyen JA Wells 2003 Direct activation of the apoptosis machinery as a mechanism to target cancer cells Proc Natl Acad Sci USA 100 7533 7538 10.1073/pnas.1031631100
25. A Eastman JR Rigas 1999 Modulation of apoptosis signaling pathways and cell cycle regulation Semin Oncol 26 7 16
26. SY Paik AC Banerjea GG Harmison CJ Chen M Schubert 1995 Inducible and conditional inhibition of human immunodeficiency virus proviral expression by vesicular stomatitis virus matrix protein J Virol 69 3529 3537
27. SA Kopecky DS Lyles 2003 Contrasting effects of matrix protein on apoptosis in HeLa and BHK cells infected with vesicular stomatitis virus are due to inhibition of host gene expression J Virol 77 4658 4669 10.1128/JVI.77.8. 4658-4669.2003
28. SA Kopecky DS Lyles 2003 The cell-rounding activity of the vesicular stomatitis virus MatrixProtein is due to the induction of cell death J Virol 77 5524 5528 10.1128/JVI.77.9.5524-5528.2003
29. DS Lyles MO McKenzie 1997 Activity of vesicular stomatitis virus M protein mutants in cell rounding is correlated with the ability to inhibit host gene expression and is not correlated with virus assembly function Virology 229 77 89 10.1006/viro.1996.8415
30. LS Her E Lund JE Dahlberg 1997 Inhibition of Ran guanosine triphosphatase-dependent nuclear transport by the matrix protein of vesicular stomatitis virus Science 276 1845 1848 10.1126/science.276.5320.1845
31. JM Petersen L Her V Varvel E Lund JE Dahlberg 2000 The matrix protein of vesicular stomatitis virus inhibits nucleocytoplasmic transport when it is in the nucleus and associated with nuclear pore complexes Mol Cell Biol 20 8590 8601 10.1128/MCB.20.22.8590-8601.2000
32. C von Kobbe JM van Deursen JP Rodrigues D Sitterlin A Bachi X Wu 2000 Vesicular stomatitis virus matrix protein inhibits host cellgene expression by targeting the nucleoporin nup98 Mol Cell 6 1243 1252 10.1016/S1097-2765(00) 00120-9
33. K Nakano KH Vousden 2001 PUMA, a novel proapoptotic gene, is induced by p53 Mol Cell 7 683 694 10.1016/S1097-2765(01)00214-3
34. E Oda R Ohki H Murasawa J Nemoto T Shibue T Yamashita 2000 Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-inducedapoptosis Science 288 1053 1058 10.1126/science.288.5468.1053
35. MC Wei WX Zong EH Cheng T Lindsten V Panoutsakopoulou AJ Ross 2001 Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death Science 292 727 730 10.1126/science.1059108
36. A Haimovitz-Friedman CC Kan D Ehleiter 1994 Ionizing radiation acts on cellularmembranes to generate ceramide and initiate apoptosis J Exp Med 180 525 535 10.1084/jem.180.2.525
37. B Zhivotovsky B Joseph S Orrenius 1999 Tumor radiosensitivityand apoptosis Exp Cell Res 248 10 17 10.1006/excr.1999.4452
38. Shiyong Li Bo Yu Ping An Gang Chen Wenping Lu Huiyun Cai 2005 Combined liposome-mediated cytosine deaminase gene therapy with radiation in killing rectal cancer cells and xenografts in athymic mice Clin Cancer Res 11 3574 3578 10.1158/1078-0432.CCR-04-2077
39. GA Patijn A Lieber L Meuse B Winther MA Kay 1998 High-efficiency retrovirus-mediated gene transfer into the livers of mice Hum Gene Ther 9 1449 1456 10.1089/hum.1998.9.10-1449
40. S Li MA Rizzo S Bhattacharya L Huang 1998 Characterization of cationic lipid-protamine-DNA (LPD) complexes for intravenous gene delivery Gene Ther 5 930 937 10.1038/sj.gt.3300683
41. Y Tan S Li BR Pitt L Huang 1999 The inhibitory role of CpG immunostimulatory motifs in cationic lipid vector mediated transgene expression in vivo Hum Gene Ther 10 2153 2161 10.1089/10430349950017149
42. K Megyeri L Orosz L Kemény 2007 Vesicular stomatitis virus infection triggers apoptosis associated with decreased DeltaNp63alpha and increased Bax levels in the immortalized HaCaT keratinocyte cell line Biomed Pharmacother 61 254 260 10.1016/j.biopha.2007.03.006
43. I Ito G Began I Mohiuddin T Saeki Y Saito CD Branch 2003 Increased uptake of liposomal-DNA complexes by lung metastases following intravenous administration Mol Ther 7 409 418 10.1016/S1525-0016(03)00004-2
44. Kevin C, Moses MA, Beecken W-D, Khan MK, Folkman J, O'Reilly MS (2001) Radiation therapy to a primary tumor accelerates metastatic growth in mice. Cancer Res 61:2207-2211