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Volumn 43, Issue 3, 1999, Pages 607-616

The effects of combining ionizing radiation and adenoviral p53 therapy in nasopharyngeal carcinoma

Author keywords

Adenovirus vector; Apoptosis; Nasopharyngeal carcinoma; p53; Radiation therapy

Indexed keywords

PROTEIN P53; VIRUS VECTOR;

EID: 0032972487     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0360-3016(98)00432-5     Document Type: Article
Times cited : (72)

References (55)
  • 1
    • 0029061122 scopus 로고
    • Undifferentiated nasopharyngeal cancer (UCNT) Current diagnostic and therapeutic aspects
    • Altun M., Fandi A., Dupuis O., et al. Undifferentiated nasopharyngeal cancer (UCNT) Current diagnostic and therapeutic aspects . Int J Radiat Oncol Biol Phys. 32:1995;859-877.
    • (1995) Int J Radiat Oncol Biol Phys , vol.32 , pp. 859-877
    • Altun, M.1    Fandi, A.2    Dupuis, O.3
  • 4
    • 0029914174 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein 1 blocks p53-mediated apoptosis through the induction of the A20 gene
    • Fries K., Miller W., Raab-Traub N. Epstein-Barr virus latent membrane protein 1 blocks p53-mediated apoptosis through the induction of the A20 gene. J Virol. 70:1996;8653-8659.
    • (1996) J Virol , vol.70 , pp. 8653-8659
    • Fries, K.1    Miller, W.2    Raab-Traub, N.3
  • 5
    • 0027973848 scopus 로고
    • The Epstein-Barr virus and nasopharyngeal carcinoma
    • Pagano J.S. The Epstein-Barr virus and nasopharyngeal carcinoma. Cancer. 74:1994;2397-2398.
    • (1994) Cancer , vol.74 , pp. 2397-2398
    • Pagano, J.S.1
  • 6
    • 0027222646 scopus 로고
    • EBNA-5, an Epstein-Barr virus-encoded nuclear antigen, binds to the retinoblastoma and p53 proteins
    • Szekely L., Selivanova G., Magnusson K.P., et al. EBNA-5, an Epstein-Barr virus-encoded nuclear antigen, binds to the retinoblastoma and p53 proteins. Proc Natl Acad Sci USA. 90:1993;5455-5459.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 5455-5459
    • Szekely, L.1    Selivanova, G.2    Magnusson, K.P.3
  • 7
    • 0028268278 scopus 로고
    • Functional and physical interaction between p53 and BZLF1: Implications for Epstein-Barr virus latency
    • Zhang Q., Gutsch D., Kenney S. Functional and physical interaction between p53 and BZLF1 Implications for Epstein-Barr virus latency . Mol Cell Biol. 14:1994;1929-1938.
    • (1994) Mol Cell Biol , vol.14 , pp. 1929-1938
    • Zhang, Q.1    Gutsch, D.2    Kenney, S.3
  • 8
    • 0028318694 scopus 로고
    • Mutant p53 increases radioresistance in rat embryo fibroblasts simultaneously transfected with HPV16-E7 and/or activated H-ras
    • Bristow R.G., Jang A., Peacock J., et al. Mutant p53 increases radioresistance in rat embryo fibroblasts simultaneously transfected with HPV16-E7 and/or activated H-ras. Oncogene. 9:1994;1527-1536.
    • (1994) Oncogene , vol.9 , pp. 1527-1536
    • Bristow, R.G.1    Jang, A.2    Peacock, J.3
  • 9
    • 0027258466 scopus 로고
    • Thymocyte apoptosis induced by p53-dependent and independent pathways
    • Clarke A.R., Purdie C., Harrison D., et al. Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature. 362:1993;849-852.
    • (1993) Nature , vol.362 , pp. 849-852
    • Clarke, A.R.1    Purdie, C.2    Harrison, D.3
  • 10
    • 0027285380 scopus 로고
    • P53 mutations increase resistance to ionizing radiation
    • Lee J.M., Bernstein A. p53 mutations increase resistance to ionizing radiation. Proc Natl Acad Sci USA. 90:1993;5742-5746.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 5742-5746
    • Lee, J.M.1    Bernstein, A.2
  • 11
    • 0027319521 scopus 로고
    • P53 is required for radiation-induced apoptosis in mouse thymocytes
    • Lowe S.W., Schmitt E.M., Smith S.W., et al. p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature. 362:1993;847-849.
    • (1993) Nature , vol.362 , pp. 847-849
    • Lowe, S.W.1    Schmitt, E.M.2    Smith, S.W.3
  • 12
    • 0030045087 scopus 로고    scopus 로고
    • Relationship between p53 status and radiosensitivity in human tumor cell lines
    • Siles E., Villalobos M., Valenzuela M., et al. Relationship between p53 status and radiosensitivity in human tumor cell lines. Br J Cancer. 73:1996;581-588.
    • (1996) Br J Cancer , vol.73 , pp. 581-588
    • Siles, E.1    Villalobos, M.2    Valenzuela, M.3
  • 13
    • 0028927179 scopus 로고
    • P53, cell cycle control and apoptosis: Implication for cancer
    • Kastan M., Canman C., Leonard C. p53, cell cycle control and apoptosis Implication for cancer . Cancer Metastasis Rev. 14:1995;3-15.
    • (1995) Cancer Metastasis Rev , vol.14 , pp. 3-15
    • Kastan, M.1    Canman, C.2    Leonard, C.3
  • 14
    • 0028359272 scopus 로고
    • DNA damage, oncogenesis and the p53 tumor-supressor gene
    • Lee J.M., Abrahamson J., Bernstein A. DNA damage, oncogenesis and the p53 tumor-supressor gene. Mutat Res. 307:1994;573-581.
    • (1994) Mutat Res , vol.307 , pp. 573-581
    • Lee, J.M.1    Abrahamson, J.2    Bernstein, A.3
  • 15
    • 0027332996 scopus 로고
    • Differential induction of transcriptionally active p53 following UV or ionizing radiation: Defects in chromosme instability syndromes
    • Lu X., Lane D. Differential induction of transcriptionally active p53 following UV or ionizing radiation: Defects in chromosme instability syndromes. Cell. 75:1993;765-778.
    • (1993) Cell , vol.75 , pp. 765-778
    • Lu, X.1    Lane, D.2
  • 16
    • 0028171454 scopus 로고
    • P53 gene mutations are associated with decreased sensitivity of human lymphoma cells to DNA damaging agents
    • Fan S., El-Deiry W., Bae I., et al. p53 gene mutations are associated with decreased sensitivity of human lymphoma cells to DNA damaging agents. Cancer Res. 54:1994;5824-5830.
    • (1994) Cancer Res , vol.54 , pp. 5824-5830
    • Fan, S.1    El-Deiry, W.2    Bae, I.3
  • 17
    • 0026318356 scopus 로고
    • Participation of p53 protein in the cellular response to DNA damage
    • Kastan M., Onyekwere O., Sidransky D., et al. Participation of p53 protein in the cellular response to DNA damage. Cancer Res. 51:1991;6304-6311.
    • (1991) Cancer Res , vol.51 , pp. 6304-6311
    • Kastan, M.1    Onyekwere, O.2    Sidransky, D.3
  • 18
    • 0026656853 scopus 로고
    • Wild-type p53 is a cell cycle checkpoint determinant following irradiation
    • Kuerbitz S., Plunkett B., Walsh W., et al. Wild-type p53 is a cell cycle checkpoint determinant following irradiation. Proc Natl Acad Sci USA. 89:1992;7491-7495.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 7491-7495
    • Kuerbitz, S.1    Plunkett, B.2    Walsh, W.3
  • 19
    • 0027451668 scopus 로고
    • P53-dependent apoptosis modulates the cytotoxicity of anticancer agents
    • Lowe S., Ruley H., Jack T., et al. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell. 74:1993;957-967.
    • (1993) Cell , vol.74 , pp. 957-967
    • Lowe, S.1    Ruley, H.2    Jack, T.3
  • 20
    • 0027944206 scopus 로고
    • P53 status and the efficacy of cancer therapy in vivo
    • Lowe S.W., Bodis S., McClatchey A., et al. p53 status and the efficacy of cancer therapy in vivo. Science. 266:1994;807-810.
    • (1994) Science , vol.266 , pp. 807-810
    • Lowe, S.W.1    Bodis, S.2    McClatchey, A.3
  • 21
    • 0027931008 scopus 로고
    • Cell cycle arrests and radiosensitivity of human tumor cell lines: Dependence on wild-type p53 for radiosensitivity
    • McIlwrath A., Vasey P., Ross G., et al. Cell cycle arrests and radiosensitivity of human tumor cell lines Dependence on wild-type p53 for radiosensitivity . Cancer Res. 54:1994;3718-3722.
    • (1994) Cancer Res , vol.54 , pp. 3718-3722
    • McIlwrath, A.1    Vasey, P.2    Ross, G.3
  • 22
    • 0027318202 scopus 로고
    • Wild-type p53 induces apoptosis in a Burkitt lumphoma (BL) line that carries mutant p53
    • Ramqvist T., Magnusson K., Wang Y., et al. Wild-type p53 induces apoptosis in a Burkitt lumphoma (BL) line that carries mutant p53. Oncogene. 8:1993;1495-1500.
    • (1993) Oncogene , vol.8 , pp. 1495-1500
    • Ramqvist, T.1    Magnusson, K.2    Wang, Y.3
  • 23
    • 0026523778 scopus 로고
    • Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line
    • Show P., Bovey R., Tardy S., et al. Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line. Proc Natl Acad Sci USA. 89:1992;4495-4499.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 4495-4499
    • Show, P.1    Bovey, R.2    Tardy, S.3
  • 24
    • 0028851771 scopus 로고
    • Adenovirus-mediated gene transfer of wild-type p53 results in melanoma cell apoptosis in vitro and in vivo
    • Cirielli C., Riccioni T., Yang C., et al. Adenovirus-mediated gene transfer of wild-type p53 results in melanoma cell apoptosis in vitro and in vivo. Int J Cancer. 63:1995;673-679.
    • (1995) Int J Cancer , vol.63 , pp. 673-679
    • Cirielli, C.1    Riccioni, T.2    Yang, C.3
  • 25
    • 0028963221 scopus 로고
    • In vivo molecular therapy with p53 adenovirus for microscopic residual head and neck squamous carcinoma
    • Clayman G., El-Naggar A., Roth J., et al. In vivo molecular therapy with p53 adenovirus for microscopic residual head and neck squamous carcinoma. Cancer Res. 55:1995;1-6.
    • (1995) Cancer Res , vol.55 , pp. 1-6
    • Clayman, G.1    El-Naggar, A.2    Roth, J.3
  • 26
    • 0029028881 scopus 로고
    • Cytotoxic effects of adenovirus-mediated wild-type p53 protein expression in normal and tumor mammary epithelial cells
    • Katayose D., Gudas J., Nguyen H., et al. Cytotoxic effects of adenovirus-mediated wild-type p53 protein expression in normal and tumor mammary epithelial cells. Cancer Res. 1:1995;889-897.
    • (1995) Cancer Res , vol.1 , pp. 889-897
    • Katayose, D.1    Gudas, J.2    Nguyen, H.3
  • 27
    • 0029017333 scopus 로고
    • Apoptosis induction mediated by wild-type p53 adenoviral gene transfer in squamous cell carcinoma of the head and neck
    • Liu T.-J., El-Naggar A., McDonnell T., et al. Apoptosis induction mediated by wild-type p53 adenoviral gene transfer in squamous cell carcinoma of the head and neck. Cancer Res. 55:1995;117-3122.
    • (1995) Cancer Res , vol.55 , pp. 117-3122
    • Liu, T.-J.1    El-Naggar, A.2    McDonnell, T.3
  • 28
    • 0029960147 scopus 로고    scopus 로고
    • Adenoviral-mediated p53 tumor suppressor gene therapy of human ovarian carcinoma
    • Mujoo K., Maneval D.C., Anderson S.C., et al. Adenoviral-mediated p53 tumor suppressor gene therapy of human ovarian carcinoma. Oncogene. 12:1996;1617-1623.
    • (1996) Oncogene , vol.12 , pp. 1617-1623
    • Mujoo, K.1    Maneval, D.C.2    Anderson, S.C.3
  • 29
    • 0030011914 scopus 로고    scopus 로고
    • Adenovirus-mediated gene transfer to human breast tumor cells: An approach for cancer gene therapy and bone marrow purging
    • Seth P., Brinkmann U., Schwartz G., et al. Adenovirus-mediated gene transfer to human breast tumor cells: An approach for cancer gene therapy and bone marrow purging. Cancer Res. 56:1996;1346-1351.
    • (1996) Cancer Res , vol.56 , pp. 1346-1351
    • Seth, P.1    Brinkmann, U.2    Schwartz, G.3
  • 30
    • 0029027072 scopus 로고
    • Adenovirus-mediated wild-type p53 expression induces apoptosis and suppresses tumorigenesis of prostatic tumor cells
    • Yang C., Cirielli C., Capogrossi M., et al. Adenovirus-mediated wild-type p53 expression induces apoptosis and suppresses tumorigenesis of prostatic tumor cells. Cancer Res. 55:1995;4120-4213.
    • (1995) Cancer Res , vol.55 , pp. 4120-4213
    • Yang, C.1    Cirielli, C.2    Capogrossi, M.3
  • 31
    • 0030743963 scopus 로고    scopus 로고
    • High-efficiency stable gene transfer of adenovirus into mammalian cells using ionizing radiation
    • Zeng M., Cerniglia G.J., Eck S., et al. High-efficiency stable gene transfer of adenovirus into mammalian cells using ionizing radiation. Hum Gene Ther. 8:1997;1025-1032.
    • (1997) Hum Gene Ther , vol.8 , pp. 1025-1032
    • Zeng, M.1    Cerniglia, G.J.2    Eck, S.3
  • 32
    • 0028403234 scopus 로고
    • High-efficiency gene transfer and high-level expression of wild-type p53 in human lung cancer cells mediated by recombinant adenovirus
    • Zhang W., Fang X., Mazur W., et al. High-efficiency gene transfer and high-level expression of wild-type p53 in human lung cancer cells mediated by recombinant adenovirus. Cancer Gene Ther. 1:1994;5-13.
    • (1994) Cancer Gene Ther , vol.1 , pp. 5-13
    • Zhang, W.1    Fang, X.2    Mazur, W.3
  • 33
    • 0030611155 scopus 로고    scopus 로고
    • 1 checkpoint and the apoptotic pathway mediated by wild-type p53 sensitizes squamous cell carcinoma of the head and neck to radiotherapy
    • 1 checkpoint and the apoptotic pathway mediated by wild-type p53 sensitizes squamous cell carcinoma of the head and neck to radiotherapy. Arch Otolaryngol Head Neck Surg. 125:1997;507-512.
    • (1997) Arch Otolaryngol Head Neck Surg , vol.125 , pp. 507-512
    • Chang, E.1    Jang, Y.-J.2    Hao, Z.3
  • 34
    • 0028231586 scopus 로고
    • Induction of chemosensitivity in human lung cancer cells in vivo by Adenovirus-mediated transfer of the wild-type p53 gene
    • Fujiwara T., Grimm E., Mukhopadhyay T., et al. Induction of chemosensitivity in human lung cancer cells in vivo by Adenovirus-mediated transfer of the wild-type p53 gene. Cancer Res. 54:1994;2287-2291.
    • (1994) Cancer Res , vol.54 , pp. 2287-2291
    • Fujiwara, T.1    Grimm, E.2    Mukhopadhyay, T.3
  • 35
    • 0029904706 scopus 로고    scopus 로고
    • Adenovirus-based transfer of wild-type p53 gene increases ovarian tumor radiosensitivity
    • Gallardo D., Drazan K., McBride W. Adenovirus-based transfer of wild-type p53 gene increases ovarian tumor radiosensitivity. Cancer Res. 56:1996;4891-4893.
    • (1996) Cancer Res , vol.56 , pp. 4891-4893
    • Gallardo, D.1    Drazan, K.2    McBride, W.3
  • 36
    • 0029555339 scopus 로고
    • Use of wild-type p53 to achieve complete treatment sensitization of tumor cells expressing endogenous mutant p53
    • Gjerset R.A., Turla S.T., Sobol R.E., et al. Use of wild-type p53 to achieve complete treatment sensitization of tumor cells expressing endogenous mutant p53. Mol Carcinog. 14:1995;275-285.
    • (1995) Mol Carcinog , vol.14 , pp. 275-285
    • Gjerset, R.A.1    Turla, S.T.2    Sobol, R.E.3
  • 37
    • 0030969022 scopus 로고    scopus 로고
    • P53 mediated sensitization of squamous cell carcinoma of the head and neck to radiotherapy
    • Pirollo K., Hao Z., Rait A., et al. p53 mediated sensitization of squamous cell carcinoma of the head and neck to radiotherapy. Oncogene. 14:1997;1735-1746.
    • (1997) Oncogene , vol.14 , pp. 1735-1746
    • Pirollo, K.1    Hao, Z.2    Rait, A.3
  • 38
    • 0029856574 scopus 로고    scopus 로고
    • Adenoviral-mediated wild-type p53 gene expression sensitizes colorectal cancer cells to ionizing radiation
    • Spitz F.R., Nguyen D., Skibber J., et al. Adenoviral-mediated wild-type p53 gene expression sensitizes colorectal cancer cells to ionizing radiation. Cancer Res. 2:1996;1665-1671.
    • (1996) Cancer Res , vol.2 , pp. 1665-1671
    • Spitz, F.R.1    Nguyen, D.2    Skibber, J.3
  • 39
    • 0031005621 scopus 로고    scopus 로고
    • Cytotoxic effects of Ad-p53 expression in two human nasopharyngeal carcinoma cell lines
    • Li J.-H., Li P., Klamut H., et al. Cytotoxic effects of Ad-p53 expression in two human nasopharyngeal carcinoma cell lines. Cl Cancer Res. 3:1997;507-514.
    • (1997) Cl Cancer Res , vol.3 , pp. 507-514
    • Li, J.-H.1    Li, P.2    Klamut, H.3
  • 40
    • 0026695141 scopus 로고
    • Alterations of the p53 gene in nasopharyngeal carcinoma
    • Effert P., McCoy R., Abdel-Hamid M., et al. Alterations of the p53 gene in nasopharyngeal carcinoma. J Virol. 66:1992;3768-3775.
    • (1992) J Virol , vol.66 , pp. 3768-3775
    • Effert, P.1    McCoy, R.2    Abdel-Hamid, M.3
  • 41
    • 0027104441 scopus 로고
    • P53 mutation in human nasopharyngeal carcinomas
    • Lo K.-W., Mok C.-H., Huang D.P., et al. p53 mutation in human nasopharyngeal carcinomas. Anticancer Res. 12:1992;1957-1964.
    • (1992) Anticancer Res , vol.12 , pp. 1957-1964
    • Lo, K.-W.1    Mok, C.-H.2    Huang, D.P.3
  • 42
    • 0020546128 scopus 로고
    • Cytogenetic studies on an epithelial cell line derived from poorly differentiated nasopharyngeal carcinoma
    • Sizhong Z., Xiukung G., Zeng Y. Cytogenetic studies on an epithelial cell line derived from poorly differentiated nasopharyngeal carcinoma. Int J Cancer. 31:1983;587-590.
    • (1983) Int J Cancer , vol.31 , pp. 587-590
    • Sizhong, Z.1    Xiukung, G.2    Zeng, Y.3
  • 43
    • 0017831748 scopus 로고
    • Establishment of an epithelioid cell line and a fusiform cell line from a patient with nasopharyngeal carcinoma
    • Zeng Y. Establishment of an epithelioid cell line and a fusiform cell line from a patient with nasopharyngeal carcinoma. Scientia Sinica. 21:1978;127.
    • (1978) Scientia Sinica , vol.21 , pp. 127
    • Zeng, Y.1
  • 45
    • 0021118703 scopus 로고
    • Quantitative analysis of dose-effect relationships: The combined effects of multiple drugs or enzyme inhibitors
    • Chou T.-C., Talalay P. Quantitative analysis of dose-effect relationships The combined effects of multiple drugs or enzyme inhibitors . Adv Enzyme Regul. 22:1984;27-55.
    • (1984) Adv Enzyme Regul , vol.22 , pp. 27-55
    • Chou, T.-C.1    Talalay, P.2
  • 46
    • 0000936624 scopus 로고
    • Cellular basis of radiotherapy
    • I.F. Tannock, & R.P. Hill. New York: Pergamon Press
    • Hill R.P. Cellular basis of radiotherapy. Tannock I.F., Hill R.P. The basic science of oncology. 1987;259-275 Pergamon Press, New York.
    • (1987) The Basic Science of Oncology , pp. 259-275
    • Hill, R.P.1
  • 48
    • 0018425119 scopus 로고
    • Exploitable mechanisms in combined radiotherapy-chemotherapy: The concept of additivity
    • Steel G.G., Peckham M.J. Exploitable mechanisms in combined radiotherapy-chemotherapy The concept of additivity . Int J Radiat Oncol Biol Phys. 5:1979;85-91.
    • (1979) Int J Radiat Oncol Biol Phys , vol.5 , pp. 85-91
    • Steel, G.G.1    Peckham, M.J.2
  • 49
    • 0027948119 scopus 로고
    • P53 status, DNA double-strand break repair proficiency, and radiation response of mouse lymphoid and myeloid cell lines
    • Radford I. p53 status, DNA double-strand break repair proficiency, and radiation response of mouse lymphoid and myeloid cell lines. Int J Radiat Biol. 66:1994;57-560.
    • (1994) Int J Radiat Biol , vol.66 , pp. 57-560
    • Radford, I.1
  • 50
    • 0030938259 scopus 로고    scopus 로고
    • P53 mediates permanent arrest over multiple cell cycles in response to γ-irradiation
    • Linke S., Clarkin K., Wahl G. p53 mediates permanent arrest over multiple cell cycles in response to γ-irradiation. Cancer Res. 57:1997;1171-1179.
    • (1997) Cancer Res , vol.57 , pp. 1171-1179
    • Linke, S.1    Clarkin, K.2    Wahl, G.3
  • 51
    • 0029315460 scopus 로고
    • Transduction of normal and malignant oral epithelium by an adenovirus vector: The effect of dose and treatment time on transduction efficiency and tissue penetration
    • Clayman G., Trapnell B., Mittereder N., et al. Transduction of normal and malignant oral epithelium by an adenovirus vector: The effect of dose and treatment time on transduction efficiency and tissue penetration. Cancer Gene Ther. 2:1995;105-111.
    • (1995) Cancer Gene Ther , vol.2 , pp. 105-111
    • Clayman, G.1    Trapnell, B.2    Mittereder, N.3
  • 52
    • 0027291957 scopus 로고
    • Dosage-dependent dominance over wild-type p53 of a mutant p53 isolated from nasopharyngeal carcinoma
    • Sun Y., Dong Z., Nakamura K., et al. Dosage-dependent dominance over wild-type p53 of a mutant p53 isolated from nasopharyngeal carcinoma. FASEB J. 7:1993;944-950.
    • (1993) FASEB J , vol.7 , pp. 944-950
    • Sun, Y.1    Dong, Z.2    Nakamura, K.3
  • 53
    • 0029802591 scopus 로고    scopus 로고
    • P53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells
    • Chen X., Ko L., Jayaraman L., et al. p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells. Gene Develop. 10:1996;2438-2451.
    • (1996) Gene Develop , vol.10 , pp. 2438-2451
    • Chen, X.1    Ko, L.2    Jayaraman, L.3
  • 54
    • 0027997836 scopus 로고
    • DNA-damaging agents greatly increase the transduction of nondividing cells by adeno-associated virus vectors
    • Alexander I.E., Russell D.W., Miller A.D. DNA-damaging agents greatly increase the transduction of nondividing cells by adeno-associated virus vectors. J Virol. 68:1994;8282-8287.
    • (1994) J Virol , vol.68 , pp. 8282-8287
    • Alexander, I.E.1    Russell, D.W.2    Miller, A.D.3
  • 55
    • 0029883821 scopus 로고    scopus 로고
    • Effects of gamma irradiation on the transduction of dividing and nondividing cells in brain and muscle of rats by adeno-associated virus vectors
    • Alexander I.E., Russell D.W., Spence A.M., et al. Effects of gamma irradiation on the transduction of dividing and nondividing cells in brain and muscle of rats by adeno-associated virus vectors. Hum Gene Ther. 7:1996;841-850.
    • (1996) Hum Gene Ther , vol.7 , pp. 841-850
    • Alexander, I.E.1    Russell, D.W.2    Spence, A.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.