메뉴 건너뛰기




Volumn 92, Issue 4, 2008, Pages 226-234

Heterogeneity in gene loci associated with type 2 diabetes on human chromosome 20q13.1

Author keywords

Association; Chromosome 20; End stage renal disease; Haplotypes; Heterogeneity; Linkage disequilibrium; SNPs; Type 2 diabetes

Indexed keywords

CADHERIN; CADHERIN LIKE 22; CARRIER PROTEIN; DICARBOXYLATE TRANSPORTER; ENGULFMENT AND CELL MOTILITY 2 PROTEIN; HEPATOCYTE NUCLEAR FACTOR 4; PHOSPHATIDYLINOSITOL 3,4,5 TRIPHOSPHATE-DEPENDENT RAC EXCHANGER 1 PROTEIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; POTASSIUM CHLORIDE COTRANSPORTER; POTASSIUM CHLORIDE COTRANSPORTER MEMBER 5; SLC12A5 PROTEIN; SODIUM DEPENDENT DICARBOXYLATE TRANSPORTER MEMBER 3; UNCLASSIFIED DRUG;

EID: 51649090840     PISSN: 08887543     EISSN: 10898646     Source Type: Journal    
DOI: 10.1016/j.ygeno.2008.06.004     Document Type: Article
Times cited : (33)

References (48)
  • 1
    • 0030897631 scopus 로고    scopus 로고
    • Linkage of genetic markers on human chromosomes 20 and 12 to NIDDM in Caucasian sib pairs with a history of diabetic nephropathy
    • Bowden D.W., et al. Linkage of genetic markers on human chromosomes 20 and 12 to NIDDM in Caucasian sib pairs with a history of diabetic nephropathy. Diabetes 46 (1997) 882-886
    • (1997) Diabetes , vol.46 , pp. 882-886
    • Bowden, D.W.1
  • 2
    • 0035878325 scopus 로고    scopus 로고
    • A high-resolution 6.0-megabase transcript map of the type 2 diabetes susceptibility region on human chromosome 20
    • Fossey S.C., et al. A high-resolution 6.0-megabase transcript map of the type 2 diabetes susceptibility region on human chromosome 20. Genomics 76 (2001) 45-57
    • (2001) Genomics , vol.76 , pp. 45-57
    • Fossey, S.C.1
  • 3
    • 0033385498 scopus 로고    scopus 로고
    • A physical map of the 20q12-q13.1 region associated with type 2 diabetes
    • Price J.A., et al. A physical map of the 20q12-q13.1 region associated with type 2 diabetes. Genomics 62 (1999) 208-215
    • (1999) Genomics , vol.62 , pp. 208-215
    • Price, J.A.1
  • 5
    • 0034797683 scopus 로고    scopus 로고
    • Sequence and functional analysis of GLUT10: a glucose transporter in the type 2 diabetes-linked region of chromosome 20q12-13.1
    • Dawson P.A., et al. Sequence and functional analysis of GLUT10: a glucose transporter in the type 2 diabetes-linked region of chromosome 20q12-13.1. Mol. Genet. Metab. 74 (2001) 186-199
    • (2001) Mol. Genet. Metab. , vol.74 , pp. 186-199
    • Dawson, P.A.1
  • 6
    • 29244481464 scopus 로고    scopus 로고
    • Genetic analysis of the GLUT10 glucose transporter (SLC2A10) polymorphisms in Caucasian American type 2 diabetes
    • Bento J.L., et al. Genetic analysis of the GLUT10 glucose transporter (SLC2A10) polymorphisms in Caucasian American type 2 diabetes. BMC Med. Genet. 6 (2005) 42
    • (2005) BMC Med. Genet. , vol.6 , pp. 42
    • Bento, J.L.1
  • 7
    • 1842422877 scopus 로고    scopus 로고
    • A common polymorphism in the upstream promoter region of the hepatocyte nuclear factor-4 alpha gene on chromosome 20q is associated with type 2 diabetes and appears to contribute to the evidence for linkage in an Ashkenazi Jewish population
    • Love-Gregory L.D., et al. A common polymorphism in the upstream promoter region of the hepatocyte nuclear factor-4 alpha gene on chromosome 20q is associated with type 2 diabetes and appears to contribute to the evidence for linkage in an Ashkenazi Jewish population. Diabetes 53 (2004) 1134-1140
    • (2004) Diabetes , vol.53 , pp. 1134-1140
    • Love-Gregory, L.D.1
  • 8
    • 12144291217 scopus 로고    scopus 로고
    • Genetic variation near the hepatocyte nuclear factor-4 alpha gene predicts susceptibility to type 2 diabetes
    • Silander K., et al. Genetic variation near the hepatocyte nuclear factor-4 alpha gene predicts susceptibility to type 2 diabetes. Diabetes 53 (2004) 1141-1149
    • (2004) Diabetes , vol.53 , pp. 1141-1149
    • Silander, K.1
  • 9
    • 15944398611 scopus 로고    scopus 로고
    • Genetic analysis of HNF4A polymorphisms in Caucasian-American type 2 diabetes
    • Bagwell A.M., et al. Genetic analysis of HNF4A polymorphisms in Caucasian-American type 2 diabetes. Diabetes 54 (2005) 1185-1190
    • (2005) Diabetes , vol.54 , pp. 1185-1190
    • Bagwell, A.M.1
  • 10
    • 7044260741 scopus 로고    scopus 로고
    • Association of protein tyrosine phosphatase 1B gene polymorphisms with type 2 diabetes
    • Bento J.L., et al. Association of protein tyrosine phosphatase 1B gene polymorphisms with type 2 diabetes. Diabetes 53 (2004) 3007-3012
    • (2004) Diabetes , vol.53 , pp. 3007-3012
    • Bento, J.L.1
  • 11
    • 7044272587 scopus 로고    scopus 로고
    • Association of protein tyrosine phosphatase 1B gene polymorphisms with measures of glucose homeostasis in Hispanic Americans: the insulin resistance atherosclerosis study (IRAS) family study
    • Palmer N.D., et al. Association of protein tyrosine phosphatase 1B gene polymorphisms with measures of glucose homeostasis in Hispanic Americans: the insulin resistance atherosclerosis study (IRAS) family study. Diabetes 53 (2004) 3013-3019
    • (2004) Diabetes , vol.53 , pp. 3013-3019
    • Palmer, N.D.1
  • 12
    • 34247873188 scopus 로고    scopus 로고
    • Search of type 2 diabetes susceptibility gene on chromosome 20q
    • Takeuchi F., et al. Search of type 2 diabetes susceptibility gene on chromosome 20q. Biochem. Biophys. Res. Commun. 357 (2007) 1100-1106
    • (2007) Biochem. Biophys. Res. Commun. , vol.357 , pp. 1100-1106
    • Takeuchi, F.1
  • 13
    • 34547536393 scopus 로고    scopus 로고
    • Common variants in WFS1 confer risk of type 2 diabetes
    • Sandhu M.S., et al. Common variants in WFS1 confer risk of type 2 diabetes. Nat. Genet. 39 (2007) 951-953
    • (2007) Nat. Genet. , vol.39 , pp. 951-953
    • Sandhu, M.S.1
  • 15
    • 18444369013 scopus 로고    scopus 로고
    • The structure of haplotype blocks in the human genome
    • Gabriel S.B., et al. The structure of haplotype blocks in the human genome. Science 296 (2002) 2225-2229
    • (2002) Science , vol.296 , pp. 2225-2229
    • Gabriel, S.B.1
  • 16
    • 0037108758 scopus 로고    scopus 로고
    • Genetic and physiological data implicating the new human gene G72 and the gene for d-amino acid oxidase in schizophrenia
    • Chumakov I., et al. Genetic and physiological data implicating the new human gene G72 and the gene for d-amino acid oxidase in schizophrenia. Proc. Natl. Acad. Sci. USA 99 (2002) 13675-13680
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 13675-13680
    • Chumakov, I.1
  • 17
    • 0035978651 scopus 로고    scopus 로고
    • Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
    • Hugot J.P., et al. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 411 (2001) 599-603
    • (2001) Nature , vol.411 , pp. 599-603
    • Hugot, J.P.1
  • 18
    • 0034785352 scopus 로고    scopus 로고
    • Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn disease
    • Rioux J.D., et al. Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn disease. Nat. Genet. 29 (2001) 223-228
    • (2001) Nat. Genet. , vol.29 , pp. 223-228
    • Rioux, J.D.1
  • 19
    • 13044277561 scopus 로고    scopus 로고
    • Type 2 diabetes: evidence for linkage on chromosome 20 in 716 Finnish affected sib pairs
    • Ghosh S., et al. Type 2 diabetes: evidence for linkage on chromosome 20 in 716 Finnish affected sib pairs. Proc. Natl. Acad. Sci. USA 96 (1999) 2198-2203
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 2198-2203
    • Ghosh, S.1
  • 20
    • 0030907295 scopus 로고    scopus 로고
    • New susceptibility locus for NIDDM is localized to human chromosome 20q
    • Ji L., et al. New susceptibility locus for NIDDM is localized to human chromosome 20q. Diabetes 46 (1997) 876-881
    • (1997) Diabetes , vol.46 , pp. 876-881
    • Ji, L.1
  • 21
    • 34249895023 scopus 로고    scopus 로고
    • Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes
    • Zeggini E., et al. Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Science 316 (2007) 1336-1341
    • (2007) Science , vol.316 , pp. 1336-1341
    • Zeggini, E.1
  • 22
    • 0036155283 scopus 로고    scopus 로고
    • Score tests for association between traits and haplotypes when linkage phase is ambiguous
    • Schaid D.J., Rowland C.M., Tines D.E., Jacobson R.M., and Poland G.A. Score tests for association between traits and haplotypes when linkage phase is ambiguous. Am. J. Hum. Genet. 70 (2002) 425-434
    • (2002) Am. J. Hum. Genet. , vol.70 , pp. 425-434
    • Schaid, D.J.1    Rowland, C.M.2    Tines, D.E.3    Jacobson, R.M.4    Poland, G.A.5
  • 23
    • 0036364293 scopus 로고    scopus 로고
    • Trend tests for case-control studies of genetic markers: power, sample size and robustness
    • Freidlin B., Zheng G., Li Z., and Gastwirth J.L. Trend tests for case-control studies of genetic markers: power, sample size and robustness. Hum. Hered. 53 (2002) 146-152
    • (2002) Hum. Hered. , vol.53 , pp. 146-152
    • Freidlin, B.1    Zheng, G.2    Li, Z.3    Gastwirth, J.L.4
  • 24
    • 0031466983 scopus 로고    scopus 로고
    • From genotypes to genes: doubling the sample size
    • Sasieni P.D. From genotypes to genes: doubling the sample size. Biometrics 53 (1997) 1253-1261
    • (1997) Biometrics , vol.53 , pp. 1253-1261
    • Sasieni, P.D.1
  • 25
    • 0035743004 scopus 로고    scopus 로고
    • Case-control studies of genetic markers: power and sample size approximations for Armitage's test for trend
    • Slager S.L., and Schaid D.J. Case-control studies of genetic markers: power and sample size approximations for Armitage's test for trend. Hum. Hered. 52 (2001) 149-153
    • (2001) Hum. Hered. , vol.52 , pp. 149-153
    • Slager, S.L.1    Schaid, D.J.2
  • 26
    • 0042567474 scopus 로고    scopus 로고
    • Use of max and min scores for trend tests for association when the genetic model is unknown
    • Zheng G. Use of max and min scores for trend tests for association when the genetic model is unknown. Stat. Med. 22 (2003) 2657-2666
    • (2003) Stat. Med. , vol.22 , pp. 2657-2666
    • Zheng, G.1
  • 27
    • 0037173040 scopus 로고    scopus 로고
    • Rac activation: P-Rex1-a convergence point for PIP(3) and Gbetagamma?
    • Weiner O.D. Rac activation: P-Rex1-a convergence point for PIP(3) and Gbetagamma?. Curr. Biol. 12 (2002) R429-R431
    • (2002) Curr. Biol. , vol.12
    • Weiner, O.D.1
  • 28
    • 0035500899 scopus 로고    scopus 로고
    • Recent duplication, domain accretion and the dynamic mutation of the human genome
    • Eichler E.E. Recent duplication, domain accretion and the dynamic mutation of the human genome. Trends Genet. 17 (2001) 661-669
    • (2001) Trends Genet. , vol.17 , pp. 661-669
    • Eichler, E.E.1
  • 29
    • 15844388826 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a newly identified member of the cadherin family, PB-cadherin
    • Sugimoto K., et al. Molecular cloning and characterization of a newly identified member of the cadherin family, PB-cadherin. J. Biol. Chem. 271 (1996) 11548-11556
    • (1996) J. Biol. Chem. , vol.271 , pp. 11548-11556
    • Sugimoto, K.1
  • 30
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
    • Wellcome Trust Case Control Consortium
    • Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447 (2007) 661-678
    • (2007) Nature , vol.447 , pp. 661-678
  • 31
    • 34249888775 scopus 로고    scopus 로고
    • Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
    • Saxena R., et al. Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science 316 (2007) 1331-1336
    • (2007) Science , vol.316 , pp. 1331-1336
    • Saxena, R.1
  • 32
    • 0034756795 scopus 로고    scopus 로고
    • Chromosomal localization of SLC12A5/Slc12a5, the human and mouse genes for the neuron-specific K(+)-Cl(-) cotransporter (KCC2) defines a new region of conserved homology
    • Sallinen R., et al. Chromosomal localization of SLC12A5/Slc12a5, the human and mouse genes for the neuron-specific K(+)-Cl(-) cotransporter (KCC2) defines a new region of conserved homology. Cytogenet. Cell Genet. 94 (2001) 67-70
    • (2001) Cytogenet. Cell Genet. , vol.94 , pp. 67-70
    • Sallinen, R.1
  • 33
    • 0034747811 scopus 로고    scopus 로고
    • CIA, a novel estrogen receptor coactivator with a bifunctional nuclear receptor interacting determinant
    • Sauve F., et al. CIA, a novel estrogen receptor coactivator with a bifunctional nuclear receptor interacting determinant. Mol. Cell. Biol. 21 (2001) 343-353
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 343-353
    • Sauve, F.1
  • 35
    • 36849035803 scopus 로고    scopus 로고
    • A 100K genome-wide association scan for diabetes and related traits in the Framingham Heart Study: replication and integration with other genome-wide datasets
    • Florez J.C., et al. A 100K genome-wide association scan for diabetes and related traits in the Framingham Heart Study: replication and integration with other genome-wide datasets. Diabetes 56 (2007) 3063-3074
    • (2007) Diabetes , vol.56 , pp. 3063-3074
    • Florez, J.C.1
  • 36
    • 36849029819 scopus 로고    scopus 로고
    • A search for variants associated with young-onset type 2 diabetes in American Indians in a 100K genotyping array
    • Hanson R.L., et al. A search for variants associated with young-onset type 2 diabetes in American Indians in a 100K genotyping array. Diabetes 56 (2007) 3045-3052
    • (2007) Diabetes , vol.56 , pp. 3045-3052
    • Hanson, R.L.1
  • 37
    • 36849081967 scopus 로고    scopus 로고
    • Identification of type 2 diabetes genes in Mexican Americans through genome-wide association studies
    • Hayes M.G., et al. Identification of type 2 diabetes genes in Mexican Americans through genome-wide association studies. Diabetes 56 (2007) 3033-3044
    • (2007) Diabetes , vol.56 , pp. 3033-3044
    • Hayes, M.G.1
  • 38
    • 36849023376 scopus 로고    scopus 로고
    • Identification of novel candidate genes for type 2 diabetes from a genome-wide association scan in the Old Order Amish: evidence for replication from diabetes-related quantitative traits and from independent populations
    • Rampersaud E., et al. Identification of novel candidate genes for type 2 diabetes from a genome-wide association scan in the Old Order Amish: evidence for replication from diabetes-related quantitative traits and from independent populations. Diabetes 56 (2007) 3053-3062
    • (2007) Diabetes , vol.56 , pp. 3053-3062
    • Rampersaud, E.1
  • 39
    • 33847176604 scopus 로고    scopus 로고
    • A genome-wide association study identifies novel risk loci for type 2 diabetes
    • Sladek R., et al. A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature 445 (2007) 881-885
    • (2007) Nature , vol.445 , pp. 881-885
    • Sladek, R.1
  • 40
    • 32544451924 scopus 로고    scopus 로고
    • Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes
    • Grant S.F., et al. Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat. Genet. 38 (2006) 320-323
    • (2006) Nat. Genet. , vol.38 , pp. 320-323
    • Grant, S.F.1
  • 41
    • 0033624575 scopus 로고    scopus 로고
    • The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes
    • Altshuler D., et al. The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes. Nat. Genet. 26 (2000) 76-80
    • (2000) Nat. Genet. , vol.26 , pp. 76-80
    • Altshuler, D.1
  • 42
    • 31944433186 scopus 로고    scopus 로고
    • Identification of basolateral membrane targeting signal of human sodium-dependent dicarboxylate transporter 3
    • Bai X., et al. Identification of basolateral membrane targeting signal of human sodium-dependent dicarboxylate transporter 3. J. Cell. Physiol. 206 (2006) 821-830
    • (2006) J. Cell. Physiol. , vol.206 , pp. 821-830
    • Bai, X.1
  • 43
    • 0035078831 scopus 로고    scopus 로고
    • Familial aggregation of coronary artery calcium in families with type 2 diabetes
    • Wagenknecht L.E., et al. Familial aggregation of coronary artery calcium in families with type 2 diabetes. Diabetes 50 (2001) 861-866
    • (2001) Diabetes , vol.50 , pp. 861-866
    • Wagenknecht, L.E.1
  • 44
    • 0036479030 scopus 로고    scopus 로고
    • Identification of a variant associated with adult-type hypolactasia
    • Enattah N.S., et al. Identification of a variant associated with adult-type hypolactasia. Nat. Genet. 30 (2002) 233-237
    • (2002) Nat. Genet. , vol.30 , pp. 233-237
    • Enattah, N.S.1
  • 45
    • 51649094928 scopus 로고    scopus 로고
    • Multiplexing the homogeneous MassEXTEND assay
    • Beaulieu M., and Hong P. Multiplexing the homogeneous MassEXTEND assay. Application Note (2004)
    • (2004) Application Note
    • Beaulieu, M.1    Hong, P.2
  • 46
    • 33748349098 scopus 로고    scopus 로고
    • iPLEXÔ assay: increased plexing efficiency and flexibility for MassARRAY system through single base primer extension with mass-modified terminators
    • Oeth P., et al. iPLEXÔ assay: increased plexing efficiency and flexibility for MassARRAY system through single base primer extension with mass-modified terminators. Application Note (2005)
    • (2005) Application Note
    • Oeth, P.1
  • 48
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: analysis and visualization of LD and haplotype maps
    • Barrett J.C., Fry B., Maller J., and Daly M.J. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 21 (2005) 263-265
    • (2005) Bioinformatics , vol.21 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3    Daly, M.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.