메뉴 건너뛰기




Volumn 49, Issue 1, 2008, Pages 13-20

Nonalcoholic fatty liver disease and metabolic syndrome: A concise review

Author keywords

Adiponectin; Insulin resistance; Metabolic syndrome; NAFLD; NASH

Indexed keywords

ADIPOSE TISSUE; CONCEPT FORMATION; FATTY LIVER; HUMAN; INSULIN RESISTANCE; METABOLIC SYNDROME X; OXIDATIVE STRESS; PHYSIOLOGY; REVIEW;

EID: 51449092910     PISSN: 12200522     EISSN: 20668279     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (21)

References (90)
  • 1
    • 0038644536 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis: Summary of an AASLD Single Topic Conference
    • Neuschwander-Tetri B. A., Caldwell S. H., Nonalcoholic steatohepatitis: summary of an AASLD Single Topic Conference, Hepatology, 2003, 37(5):1202-1219.
    • (2003) Hepatology , vol.37 , Issue.5 , pp. 1202-1219
    • Neuschwander-Tetri, B.A.1    Caldwell, S.H.2
  • 2
    • 24044536090 scopus 로고    scopus 로고
    • Recent concepts in non-alcoholic fatty liver disease
    • Adams L. A., Angulo P., Recent concepts in non-alcoholic fatty liver disease, Diabet Med, 2005, 22(9):1129-1133.
    • (2005) Diabet Med , vol.22 , Issue.9 , pp. 1129-1133
    • Adams, L.A.1    Angulo, P.2
  • 3
    • 34250326350 scopus 로고    scopus 로고
    • Guidelines for the assessment and management of non-alcoholic fatty liver disease in the Asia-Pacific region: Executive summary
    • Asia-Pacific Working Party on NAFLD
    • Farrell G. C., Chitturi S., Lau G. K., Sollano J. D.; Asia-Pacific Working Party on NAFLD, Guidelines for the assessment and management of non-alcoholic fatty liver disease in the Asia-Pacific region: executive summary, J Gastroenterol Hepatol, 2007, 22(6):775-777.
    • (2007) J Gastroenterol Hepatol , vol.22 , Issue.6 , pp. 775-777
    • Farrell, G.C.1    Chitturi, S.2    Lau, G.K.3    Sollano, J.D.4
  • 4
    • 0037129380 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease
    • Angulo P., Nonalcoholic fatty liver disease, N Engl J Med, 2002, 346(16):1221-1231.
    • (2002) N Engl J Med , vol.346 , Issue.16 , pp. 1221-1231
    • Angulo, P.1
  • 5
    • 33644547706 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: From steatosis to cirrhosis
    • Farrell G. C., Larter C. Z., Nonalcoholic fatty liver disease: from steatosis to cirrhosis, Hepatology, 2006, 43(2 Suppl 1):S99-S112.
    • (2006) Hepatology , vol.43 , Issue.2 SUPPL. 1
    • Farrell, G.C.1    Larter, C.Z.2
  • 6
    • 0019152816 scopus 로고
    • Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease
    • Ludwig J., Viggiano T. R., McGill D. B., Oh B. J., Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease, Mayo Clin Proc, 1980, 55(7):434-438.
    • (1980) Mayo Clin Proc , vol.55 , Issue.7 , pp. 434-438
    • Ludwig, J.1    Viggiano, T.R.2    McGill, D.B.3    Oh, B.J.4
  • 7
  • 8
    • 0038805259 scopus 로고    scopus 로고
    • The prevalence and etiology of elevated aminotransferase levels in the United States
    • Clark J. M., Brancati F. L., Diehl A. M., The prevalence and etiology of elevated aminotransferase levels in the United States, Am J Gastroenterol, 2003, 98(5):960-967.
    • (2003) Am J Gastroenterol , vol.98 , Issue.5 , pp. 960-967
    • Clark, J.M.1    Brancati, F.L.2    Diehl, A.M.3
  • 9
    • 0032822946 scopus 로고    scopus 로고
    • Prospective evaluation of unexplained chronic liver transaminase abnormalities in asymptomatic and symptomatic patients
    • Daniel S., Ben-Menachem T., Vasudevan G., Ma C. K., Blumenkehl M., Prospective evaluation of unexplained chronic liver transaminase abnormalities in asymptomatic and symptomatic patients, Am J Gastroenterol, 1999, 94(10):3010-3014.
    • (1999) Am J Gastroenterol , vol.94 , Issue.10 , pp. 3010-3014
    • Daniel, S.1    Ben-Menachem, T.2    Vasudevan, G.3    Ma, C.K.4    Blumenkehl, M.5
  • 12
    • 24044467100 scopus 로고    scopus 로고
    • Prevalence of non-alcoholic fatty liver disease and its association with impaired glucose metabolism in Japanese adults
    • Jimba S., Nakagami T., Takahashi M., Wakamatsu T., Hirota Y., Iwamoto Y., Wasada T., Prevalence of non-alcoholic fatty liver disease and its association with impaired glucose metabolism in Japanese adults, Diabet Med, 2005, 22(9):1141-1145.
    • (2005) Diabet Med , vol.22 , Issue.9 , pp. 1141-1145
    • Jimba, S.1    Nakagami, T.2    Takahashi, M.3    Wakamatsu, T.4    Hirota, Y.5    Iwamoto, Y.6    Wasada, T.7
  • 14
    • 0345762540 scopus 로고
    • Associazione di iperlipemia, diabete mellito e obesità di medio grado
    • Avogaro P., Crepaldi G., Enzi G., Tiengo A., Associazione di iperlipemia, diabete mellito e obesità di medio grado, Acta Diabetol Lat, 1967, 4(4):572-590.
    • (1967) Acta Diabetol Lat , vol.4 , Issue.4 , pp. 572-590
    • Avogaro, P.1    Crepaldi, G.2    Enzi, G.3    Tiengo, A.4
  • 15
    • 0024160877 scopus 로고
    • Banting Lecture 1988. Role of insulin resistance in human disease
    • Reaven G. M., Banting Lecture 1988. Role of insulin resistance in human disease, Diabetes, 1988, 37(12):1595-1607.
    • (1988) Diabetes , vol.37 , Issue.12 , pp. 1595-1607
    • Reaven, G.M.1
  • 16
    • 0031851293 scopus 로고    scopus 로고
    • Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus: Provisional report of a WHO consultation
    • Alberti K. G., Zimmet P. Z., Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus: provisional report of a WHO consultation, Diabet Med, 1998, 15(7):539-553.
    • (1998) Diabet Med , vol.15 , Issue.7 , pp. 539-553
    • Alberti, K.G.1    Zimmet, P.Z.2
  • 18
    • 0035897696 scopus 로고    scopus 로고
    • Executive summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
    • Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults
    • Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults, Executive summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III), JAMA, 2001, 285(19):2486-2497.
    • (2001) JAMA , vol.285 , Issue.19 , pp. 2486-2497
  • 20
    • 25144459980 scopus 로고    scopus 로고
    • The metabolic syndrome-a new worldwide definition
    • IDF Epidemiology Task Force Consensus Group
    • Alberti K. G., Zimmet P., Shaw J.; IDF Epidemiology Task Force Consensus Group, The metabolic syndrome-a new worldwide definition, Lancet, 2005, 366(9491):1059-1062.
    • (2005) Lancet , vol.366 , Issue.9491 , pp. 1059-1062
    • Alberti, K.G.1    Zimmet, P.2    Shaw, J.3
  • 21
    • 27444443876 scopus 로고    scopus 로고
    • Diagnosis and management of the metabolic syndrome: An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement
    • American Heart Association; National Heart, Lung, and Blood Institute
    • Grundy S. M., Cleeman J. I., Daniels S. R., Donato K. A., Eckel R. H., Franklin B. A., Gordon D. J., Krauss R. M., Savage P. J., Smith S. C. Jr., Spertus J. A., Costa F.; American Heart Association; National Heart, Lung, and Blood Institute, Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement, Circulation, 2005, 112(17):2735-2752; e285-e290.
    • (2005) Circulation , vol.112 , Issue.17
    • Grundy, S.M.1    Cleeman, J.I.2    Daniels, S.R.3    Donato, K.A.4    Eckel, R.H.5    Franklin, B.A.6    Gordon, D.J.7    Krauss, R.M.8    Savage, P.J.9    Smith Jr., S.C.10    Spertus, J.A.11    Costa, F.12
  • 22
    • 0031947715 scopus 로고    scopus 로고
    • Steatohepatitis: A tale of two "hits"?
    • Day C. P., James O. F., Steatohepatitis: a tale of two "hits"?, Gastroenterology, 1998, 114(4):842-845.
    • (1998) Gastroenterology , vol.114 , Issue.4 , pp. 842-845
    • Day, C.P.1    James, O.F.2
  • 23
    • 30944455145 scopus 로고    scopus 로고
    • Insulin resistance: A metabolic pathway to chronic liver disease
    • Bugianesi E., McCullough A. J., Marchesini G., Insulin resistance: a metabolic pathway to chronic liver disease, Hepatology, 2005, 42(5): 987-1000.
    • (2005) Hepatology , vol.42 , Issue.5 , pp. 987-1000
    • Bugianesi, E.1    McCullough, A.J.2    Marchesini, G.3
  • 25
    • 4344628553 scopus 로고    scopus 로고
    • Insulin resistance and the pathogenesis of nonalcoholic fatty liver disease
    • Choudhury J., Sanyal A. J., Insulin resistance and the pathogenesis of nonalcoholic fatty liver disease, Clin Liver Dis, 2004, 8(3):575-594.
    • (2004) Clin Liver Dis , vol.8 , Issue.3 , pp. 575-594
    • Choudhury, J.1    Sanyal, A.J.2
  • 27
    • 4043077961 scopus 로고    scopus 로고
    • Molecular mediators of hepatic steatosis and liver injury
    • Browning J. D., Horton J. D., Molecular mediators of hepatic steatosis and liver injury, J Clin Invest, 2004, 114(2):147-152.
    • (2004) J Clin Invest , vol.114 , Issue.2 , pp. 147-152
    • Browning, J.D.1    Horton, J.D.2
  • 28
    • 0036780582 scopus 로고    scopus 로고
    • Pathogenesis of steatohepatitis
    • Day C. P., Pathogenesis of steatohepatitis, Best Pract Res Clin Gastroenterol, 2002, 16(5):663-678.
    • (2002) Best Pract Res Clin Gastroenterol , vol.16 , Issue.5 , pp. 663-678
    • Day, C.P.1
  • 29
    • 0035991444 scopus 로고    scopus 로고
    • In situ detection of lipid peroxidation and oxidative DNA damage in non-alcoholic fatty liver diseases
    • Seki S., Kitada T., Yamada T., Sakaguchi H., Nakatani K., Wakasa K., In situ detection of lipid peroxidation and oxidative DNA damage in non-alcoholic fatty liver diseases, J Hepatol, 2002, 37(1):56-62.
    • (2002) J Hepatol , vol.37 , Issue.1 , pp. 56-62
    • Seki, S.1    Kitada, T.2    Yamada, T.3    Sakaguchi, H.4    Nakatani, K.5    Wakasa, K.6
  • 30
    • 0036080591 scopus 로고    scopus 로고
    • Nonalcoholic steatosis and steatohepatitis. V. Mitochondrial dysfunction in steatohepatitis
    • Pessayre D., Mansouri A., Fromenty B., Nonalcoholic steatosis and steatohepatitis. V. Mitochondrial dysfunction in steatohepatitis, Am J Physiol Gastrointest Liver Physiol, 2002, 282(2):G193-199.
    • (2002) Am J Physiol Gastrointest Liver Physiol , vol.282 , Issue.2
    • Pessayre, D.1    Mansouri, A.2    Fromenty, B.3
  • 31
    • 0035196704 scopus 로고    scopus 로고
    • Nonalcoholic steatosis and steatohepatitis. II. Cytochrome P-450 enzymes and oxidative stress
    • Robertson G., Leclercq I., Farrell G. C., Nonalcoholic steatosis and steatohepatitis. II. Cytochrome P-450 enzymes and oxidative stress, Am J Physiol Gastrointest Liver Physiol, 2001, 28(5):G1135-1139.
    • (2001) Am J Physiol Gastrointest Liver Physiol , vol.28 , Issue.5
    • Robertson, G.1    Leclercq, I.2    Farrell, G.C.3
  • 33
    • 21044437187 scopus 로고    scopus 로고
    • Immune response towards lipid peroxidation products as a predictor of progression of non-alcoholic fatty liver disease to advanced fibrosis
    • Albano E., Mottaran E., Vidali M., Reale E., Saksena S., Occhino G., Burt A. D., Day C. P., Immune response towards lipid peroxidation products as a predictor of progression of non-alcoholic fatty liver disease to advanced fibrosis, Gut, 2005, 54(7):987-993.
    • (2005) Gut , vol.54 , Issue.7 , pp. 987-993
    • Albano, E.1    Mottaran, E.2    Vidali, M.3    Reale, E.4    Saksena, S.5    Occhino, G.6    Burt, A.D.7    Day, C.P.8
  • 34
    • 0023663615 scopus 로고
    • Adipsin: A circulating serine protease homolog secreted by adipose tissue and sciatic nerve
    • Cook K. S., Min H. Y., Johnson D., Chaplinsky R. J., Flier J. S., Hunt C. R., Spiegelman B. M., Adipsin: a circulating serine protease homolog secreted by adipose tissue and sciatic nerve, Science, 1987, 237(4813):402-405.
    • (1987) Science , vol.237 , Issue.4813 , pp. 402-405
    • Cook, K.S.1    Min, H.Y.2    Johnson, D.3    Chaplinsky, R.J.4    Flier, J.S.5    Hunt, C.R.6    Spiegelman, B.M.7
  • 35
    • 0033789518 scopus 로고    scopus 로고
    • Adipose tissue as an endocrine organ
    • Ahima R. S., Flier J. S., Adipose tissue as an endocrine organ, Trends Endocrinol Metab, 2000, 11(8):327-332.
    • (2000) Trends Endocrinol Metab , vol.11 , Issue.8 , pp. 327-332
    • Ahima, R.S.1    Flier, J.S.2
  • 36
    • 33644911756 scopus 로고    scopus 로고
    • The endocrine function of adipose tissue: An update
    • Ronti T., Lupattelli G., Mannarino E., The endocrine function of adipose tissue: an update, Clin Endocrinol (Oxf), 2006, 64(4):355-365.
    • (2006) Clin Endocrinol (Oxf) , vol.64 , Issue.4 , pp. 355-365
    • Ronti, T.1    Lupattelli, G.2    Mannarino, E.3
  • 37
    • 2042480671 scopus 로고    scopus 로고
    • Comparison of the release of adipokines by adipose tissue, adipose tissue matrix, and adipocytes from visceral and subcutaneous abdominal adipose tissues of obese humans
    • Fain J. N., Madan A. K., Hiler M. L., Cheema P., Bahouth S. W., Comparison of the release of adipokines by adipose tissue, adipose tissue matrix, and adipocytes from visceral and subcutaneous abdominal adipose tissues of obese humans, Endocrinology, 2004, 145(5):2273-2282.
    • (2004) Endocrinology , vol.145 , Issue.5 , pp. 2273-2282
    • Fain, J.N.1    Madan, A.K.2    Hiler, M.L.3    Cheema, P.4    Bahouth, S.W.5
  • 39
    • 0036266125 scopus 로고    scopus 로고
    • Altered tumor necrosis factor-alpha (TNF-alpha) processing in adipocytes and increased expression of transmembrane TNF-alpha in obesity
    • Xu H., Uysal K. T., Becherer J. D., Arner P., Hotamisligil G. S., Altered tumor necrosis factor-alpha (TNF-alpha) processing in adipocytes and increased expression of transmembrane TNF-alpha in obesity, Diabetes, 2002, 51(6):1876-1883.
    • (2002) Diabetes , vol.51 , Issue.6 , pp. 1876-1883
    • Xu, H.1    Uysal, K.T.2    Becherer, J.D.3    Arner, P.4    Hotamisligil, G.S.5
  • 41
    • 0028787490 scopus 로고
    • A novel serum protein similar to C1q, produced exclusively in adipocytes
    • Scherer P. E., Williams S., Fogliano M., Baldini G., Lodish H. F., A novel serum protein similar to C1q, produced exclusively in adipocytes, J Biol Chem, 1995, 270(45):26746-26749.
    • (1995) J Biol Chem , vol.270 , Issue.45 , pp. 26746-26749
    • Scherer, P.E.1    Williams, S.2    Fogliano, M.3    Baldini, G.4    Lodish, H.F.5
  • 42
    • 0036511213 scopus 로고    scopus 로고
    • ACRP30/adiponectin: An adipokine regulating glucose and lipid metabolism
    • Berg A. H., Combs T. P., Scherer P. E., ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism, Trends Endocrinol Metab, 2002, 13(2):84-89.
    • (2002) Trends Endocrinol Metab , vol.13 , Issue.2 , pp. 84-89
    • Berg, A.H.1    Combs, T.P.2    Scherer, P.E.3
  • 44
    • 0842328001 scopus 로고    scopus 로고
    • Update on adipocyte hormones: Regulation of energy balance and carbohydrate/lipid metabolism
    • Havel P. J., Update on adipocyte hormones: regulation of energy balance and carbohydrate/lipid metabolism, Diabetes, 2004, 53(Suppl 1):S143-151.
    • (2004) Diabetes , vol.53 , Issue.SUPPL. 1
    • Havel, P.J.1
  • 45
    • 0034999667 scopus 로고    scopus 로고
    • Hypoadiponectinemia in obesity and type 2 diabetes: Close association with insulin resistance and hyperinsulinemia
    • Weyer C., Funahashi T., Tanaka S., Hotta K., Matsuzawa Y., Pratley R. E., Tataranni P. A., Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia, J Clin Endocrinol Metab, 2001, 86(5):1930-1935.
    • (2001) J Clin Endocrinol Metab , vol.86 , Issue.5 , pp. 1930-1935
    • Weyer, C.1    Funahashi, T.2    Tanaka, S.3    Hotta, K.4    Matsuzawa, Y.5    Pratley, R.E.6    Tataranni, P.A.7
  • 48
    • 0041302377 scopus 로고    scopus 로고
    • The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice
    • Xu A., Wang Y., Keshaw H., Xu L.Y., Lam K.S., Cooper G.J., The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice, J Clin Invest, 2003, 112(1):91-100.
    • (2003) J Clin Invest , vol.112 , Issue.1 , pp. 91-100
    • Xu, A.1    Wang, Y.2    Keshaw, H.3    Xu, L.Y.4    Lam, K.S.5    Cooper, G.J.6
  • 49
    • 33745062827 scopus 로고    scopus 로고
    • Adiponectin, structure, function and pathophysiological implications in non-alcoholic fatty liver disease
    • Méndez-Sánchez N., Chavez-Tapia N. C., ZamoraValdés D., Uribe M., Adiponectin, structure, function and pathophysiological implications in non-alcoholic fatty liver disease, Mini Rev Med Chem, 2006, 6(6):651-656.
    • (2006) Mini Rev Med Chem , vol.6 , Issue.6 , pp. 651-656
    • Méndez-Sánchez, N.1    Chavez-Tapia, N.C.2    ZamoraValdés, D.3    Uribe, M.4
  • 52
    • 0036750241 scopus 로고    scopus 로고
    • Adiponectin-its role in metabolism and beyond
    • Stefan N., Stumvoll M., Adiponectin-its role in metabolism and beyond, Horm Metab Res, 2002, 34(9):469-474.
    • (2002) Horm Metab Res , vol.34 , Issue.9 , pp. 469-474
    • Stefan, N.1    Stumvoll, M.2
  • 53
    • 0034881391 scopus 로고    scopus 로고
    • The adipocyte-secreted protein Acrp30 enhances hepatic insulin action
    • Berg A. H., Combs T. P., Du X., Brownlee M., Scherer P. E., The adipocyte-secreted protein Acrp30 enhances hepatic insulin action, Nat Med, 2001, 7(8):947-953.
    • (2001) Nat Med , vol.7 , Issue.8 , pp. 947-953
    • Berg, A.H.1    Combs, T.P.2    Du, X.3    Brownlee, M.4    Scherer, P.E.5
  • 54
    • 3042699353 scopus 로고    scopus 로고
    • Adiponectin protects LPS-induced liver injury through modulation of TNF-alpha in KK-Ay obese mice
    • Masaki T., Chiba S., Tatsukawa H., Yasuda T., Noguchi H., Seike M., Yoshimatsu H., Adiponectin protects LPS-induced liver injury through modulation of TNF-alpha in KK-Ay obese mice, Hepatology, 2004, 40(1):177-184.
    • (2004) Hepatology , vol.40 , Issue.1 , pp. 177-184
    • Masaki, T.1    Chiba, S.2    Tatsukawa, H.3    Yasuda, T.4    Noguchi, H.5    Seike, M.6    Yoshimatsu, H.7
  • 56
    • 4544334655 scopus 로고    scopus 로고
    • Adiponectin induces the antiinflammatory cytokines IL-10 and IL-1RA in human leukocytes
    • Wolf A. M., Wolf D., Rumpold H., Enrich B., Tilg H., Adiponectin induces the antiinflammatory cytokines IL-10 and IL-1RA in human leukocytes, Biochem Biophys Res Commun, 2004, 323(2):630-635.
    • (2004) Biochem Biophys Res Commun , vol.323 , Issue.2 , pp. 630-635
    • Wolf, A.M.1    Wolf, D.2    Rumpold, H.3    Enrich, B.4    Tilg, H.5
  • 59
    • 0034676629 scopus 로고    scopus 로고
    • Cytokines in alcoholic and nonalcoholic steatohepatitis
    • Tilg H., Diehl A. M., Cytokines in alcoholic and nonalcoholic steatohepatitis, N Engl J Med, 2000, 343(20):1467-1476.
    • (2000) N Engl J Med , vol.343 , Issue.20 , pp. 1467-1476
    • Tilg, H.1    Diehl, A.M.2
  • 60
    • 0032510463 scopus 로고    scopus 로고
    • The crystal structure of a complement-1q family protein suggests an evolutionary link to tumor necrosis factor
    • Shapiro L., Scherer P. E., The crystal structure of a complement-1q family protein suggests an evolutionary link to tumor necrosis factor, Curr Biol, 1998, 8(6):335-338.
    • (1998) Curr Biol , vol.8 , Issue.6 , pp. 335-338
    • Shapiro, L.1    Scherer, P.E.2
  • 62
    • 0027332738 scopus 로고
    • Tumor necrosis factor-α suppresses insulin-induced tyrosine phosphorylation of insulin receptor and its substrates
    • Feinstein R., Kanety H., Papa M. Z., Lunenfeld B., Karasik A., Tumor necrosis factor-α suppresses insulin-induced tyrosine phosphorylation of insulin receptor and its substrates, J. Biol Chem, 1993, 268(35):26055-26058.
    • (1993) J. Biol Chem , vol.268 , Issue.35 , pp. 26055-26058
    • Feinstein, R.1    Kanety, H.2    Papa, M.Z.3    Lunenfeld, B.4    Karasik, A.5
  • 63
    • 0027459878 scopus 로고
    • Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance
    • Hotamisligil G. S., Shargill N. S., Spiegelman B. M., Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance, Science, 1993, 259(5091):87-91.
    • (1993) Science , vol.259 , Issue.5091 , pp. 87-91
    • Hotamisligil, G.S.1    Shargill, N.S.2    Spiegelman, B.M.3
  • 66
    • 14644427890 scopus 로고    scopus 로고
    • Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB
    • Cai D., Yuan M., Frantz D. F., Melendez P. A., Hansen L., Lee J., Shoelson S. E., Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB, Nat Med, 2005, 11(2):183-190.
    • (2005) Nat Med , vol.11 , Issue.2 , pp. 183-190
    • Cai, D.1    Yuan, M.2    Frantz, D.F.3    Melendez, P.A.4    Hansen, L.5    Lee, J.6    Shoelson, S.E.7
  • 67
    • 27644473284 scopus 로고    scopus 로고
    • Role of inflammation in nonalcoholic steatohepatitis
    • Choi S., Diehl A. M., Role of inflammation in nonalcoholic steatohepatitis, Curr Opin Gastroenterol, 2005, 21(6):702-707.
    • (2005) Curr Opin Gastroenterol , vol.21 , Issue.6 , pp. 702-707
    • Choi, S.1    Diehl, A.M.2
  • 69
    • 0036022846 scopus 로고    scopus 로고
    • Leptin is essential for the hepatic fibrogenic response to chronic liver injury
    • Leclercq I. A., Farrell G. C., Schriemer R., Robertson G. R., Leptin is essential for the hepatic fibrogenic response to chronic liver injury, J Hepatol, 2002, 37(2):206-213.
    • (2002) J Hepatol , vol.37 , Issue.2 , pp. 206-213
    • Leclercq, I.A.1    Farrell, G.C.2    Schriemer, R.3    Robertson, G.R.4
  • 70
    • 4344595660 scopus 로고    scopus 로고
    • The potential role of genes in nonalcoholic fatty liver disease
    • Day C. P., The potential role of genes in nonalcoholic fatty liver disease, Clin Liver Dis, 2004, 8(3):673-691.
    • (2004) Clin Liver Dis , vol.8 , Issue.3 , pp. 673-691
    • Day, C.P.1
  • 71
    • 33748169641 scopus 로고    scopus 로고
    • Genetic influences in nonalcoholic fatty liver disease
    • Merriman R. B., Aouizerat B. E, Bass N. M., Genetic influences in nonalcoholic fatty liver disease, J Clin Gastroenterol, 2006, 40(3 Suppl 1):S30-33.
    • (2006) J Clin Gastroenterol , vol.40 , Issue.3 SUPPL. 1
    • Merriman, R.B.1    Aouizerat, B.E.2    Bass, N.M.3
  • 72
    • 33749597707 scopus 로고    scopus 로고
    • Genes or environment to determine alcoholic liver disease and non-alcoholic fatty liver disease
    • Day C. P., Genes or environment to determine alcoholic liver disease and non-alcoholic fatty liver disease, Liver Int, 2006, 26(9):1021-1028.
    • (2006) Liver Int , vol.26 , Issue.9 , pp. 1021-1028
    • Day, C.P.1
  • 73
    • 17844388556 scopus 로고    scopus 로고
    • Endocannabinoid control of food intake and energy balance
    • Di Marzo V., Matias I., Endocannabinoid control of food intake and energy balance, Nat Neurosci, 2005, 8(5):585-589.
    • (2005) Nat Neurosci , vol.8 , Issue.5 , pp. 585-589
    • Di Marzo, V.1    Matias, I.2
  • 76
    • 34247200322 scopus 로고    scopus 로고
    • Non-alcoholic fatty liver disease in the Asia-Pacific region: Definitions and overview of proposed guidelines
    • Asia-Pacific Working Party on NAFLD
    • Chitturi S., Farrell G. C., Hashimoto E., Saibara T., Lau G. K., Sollano J. D.; Asia-Pacific Working Party on NAFLD, Non-alcoholic fatty liver disease in the Asia-Pacific region: definitions and overview of proposed guidelines, J Gastroenterol Hepatol, 2007, 22(6):778-787.
    • (2007) J Gastroenterol Hepatol , vol.22 , Issue.6 , pp. 778-787
    • Chitturi, S.1    Farrell, G.C.2    Hashimoto, E.3    Saibara, T.4    Lau, G.K.5    Sollano, J.D.6
  • 77
    • 33947284587 scopus 로고    scopus 로고
    • How should we manage patients with non-alcoholic fatty liver disease in 2007?
    • Asia-Pacific Working Party on NAFLD
    • Chan H. L., de Silva H. J., Leung N. W., Lim S. G., Farrell G. C.; Asia-Pacific Working Party on NAFLD, How should we manage patients with non-alcoholic fatty liver disease in 2007?, J Gastroenterol Hepatol, 2007, 22(6):801-808.
    • (2007) J Gastroenterol Hepatol , vol.22 , Issue.6 , pp. 801-808
    • Chan, H.L.1    de Silva, H.J.2    Leung, N.W.3    Lim, S.G.4    Farrell, G.C.5
  • 78
    • 0036176194 scopus 로고    scopus 로고
    • Update on nonalcoholic fatty liver disease
    • McCullough A. J., Update on nonalcoholic fatty liver disease, J Clin Gastroenterol, 2002, 34(3):255-262.
    • (2002) J Clin Gastroenterol , vol.34 , Issue.3 , pp. 255-262
    • McCullough, A.J.1
  • 79
    • 34250332701 scopus 로고    scopus 로고
    • What are the risk factors and settings for non-alcoholic fatty liver disease in Asia-Pacific?
    • Asia-Pacific Working Party for NAFLD
    • Fan J. G., Saibara T., Chitturi S., Kim B. I., Sung J. J., Chutaputti A.; Asia-Pacific Working Party for NAFLD, What are the risk factors and settings for non-alcoholic fatty liver disease in Asia-Pacific?, J Gastroenterol Hepatol, 2007, 22(6):794-800.
    • (2007) J Gastroenterol Hepatol , vol.22 , Issue.6 , pp. 794-800
    • Fan, J.G.1    Saibara, T.2    Chitturi, S.3    Kim, B.I.4    Sung, J.J.5    Chutaputti, A.6
  • 81
    • 0033849619 scopus 로고    scopus 로고
    • Practices of liver biopsy in France: Results of a prospective nationwide survey. For the Group of Epidemiology of the French Association for the Study of the Liver (AFEF)
    • Cadranel J. F., Rufat P., Degos F., Practices of liver biopsy in France: results of a prospective nationwide survey. For the Group of Epidemiology of the French Association for the Study of the Liver (AFEF), Hepatology, 2000, 32(3):477-481.
    • (2000) Hepatology , vol.32 , Issue.3 , pp. 477-481
    • Cadranel, J.F.1    Rufat, P.2    Degos, F.3
  • 84
    • 8444233581 scopus 로고    scopus 로고
    • Role of liver biopsy in the assessment of non-alcoholic fatty liver disease
    • Hübscher S. G., Role of liver biopsy in the assessment of non-alcoholic fatty liver disease, Eur J Gastroenterol Hepatol, 2004, 16(11):1107-1115.
    • (2004) Eur J Gastroenterol Hepatol , vol.16 , Issue.11 , pp. 1107-1115
    • Hübscher, S.G.1
  • 86
    • 0032695030 scopus 로고    scopus 로고
    • Independent predictors of liver fibrosis in patients with nonalcoholic steatohepatitis
    • Angulo P., Keach J. C., Batts K. P., Lindor K. D., Independent predictors of liver fibrosis in patients with nonalcoholic steatohepatitis, Hepatology, 1999, 30(6):1356-1362.
    • (1999) Hepatology , vol.30 , Issue.6 , pp. 1356-1362
    • Angulo, P.1    Keach, J.C.2    Batts, K.P.3    Lindor, K.D.4
  • 87
    • 33750576507 scopus 로고    scopus 로고
    • Usefulness of serum hepatic fibrosis markers in the diagnosis of nonalcoholic steatohepatitis (NASH)
    • Sasaki N., Ueno T., Morita Y., Nagata E., Sata M., Usefulness of serum hepatic fibrosis markers in the diagnosis of nonalcoholic steatohepatitis (NASH), Hepatogastroenterology, 2006, 53(71):678-681.
    • (2006) Hepatogastroenterology , vol.53 , Issue.71 , pp. 678-681
    • Sasaki, N.1    Ueno, T.2    Morita, Y.3    Nagata, E.4    Sata, M.5
  • 88
    • 33750312195 scopus 로고    scopus 로고
    • Non-invasive markers associated with liver fibrosis in non-alcoholic fatty liver disease
    • Guha I. N., Parkes J., Roderick P. R., Harris S., Rosenberg W. M., Non-invasive markers associated with liver fibrosis in non-alcoholic fatty liver disease, Gut, 2006, 55(11):1650-1660.
    • (2006) Gut , vol.55 , Issue.11 , pp. 1650-1660
    • Guha, I.N.1    Parkes, J.2    Roderick, P.R.3    Harris, S.4    Rosenberg, W.M.5
  • 89
    • 34547683485 scopus 로고    scopus 로고
    • Evaluation and management of obesity-related nonalcoholic fatty liver disease
    • Nugent C., Younossi Z. M., Evaluation and management of obesity-related nonalcoholic fatty liver disease, Nat Clin Pract Gastroenterol Hepatol, 2007, 4(8):432-441.
    • (2007) Nat Clin Pract Gastroenterol Hepatol , vol.4 , Issue.8 , pp. 432-441
    • Nugent, C.1    Younossi, Z.M.2
  • 90
    • 20444506049 scopus 로고    scopus 로고
    • Treatment strategies in nonalcoholic fatty liver disease
    • Tilg H., Kaser A., Treatment strategies in nonalcoholic fatty liver disease, Nat Clin Pract Gastroenterol Hepatol, 2005, 2(3):148-155.
    • (2005) Nat Clin Pract Gastroenterol Hepatol , vol.2 , Issue.3 , pp. 148-155
    • Tilg, H.1    Kaser, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.