Identification of putative active site residues of ACAT enzymes

Journal of Lipid Research

Volumn 49, Issue 8, 2008, Pages 1770-1781

  Das, Akash ^a   Davis, Matthew A ^a   Rudel, Lawrence L ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

ACAT; Catalytic triad; Cholesterol; Cholesteryl ester

Indexed keywords

ACETYL COENZYME A ACETYLTRANSFERASE; ASPARTIC ACID; FATTY ACID SYNTHASE; HISTIDINE; SERINE; THIOL ESTER HYDROLASE; TYROSINE; CHOLESTEROL ACYLTRANSFERASE; STEROL O ACYLTRANSFERASE 1; STEROL O ACYLTRANSFERASE 2; STEROL O-ACYLTRANSFERASE 1; STEROL O-ACYLTRANSFERASE 2;

AMINO ACID COMPOSITION; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CERCOPITHECIDAE; CHO CELL; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME STABILITY; FEMALE; GENE MUTATION; GENETIC CONSERVATION; MUTAGENESIS; MUTATIONAL ANALYSIS; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN MOTIF; AMINO ACID SEQUENCE; ANIMAL; BINDING SITE; CERCOPITHECUS; CHEMISTRY; CRICETULUS; GENETICS; HAMSTER; MOLECULAR GENETICS; POINT MUTATION; PROTEIN FOLDING; SEQUENCE ALIGNMENT; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANIMALS; ASPARTIC ACID; BINDING SITES; CERCOPITHECUS AETHIOPS; CHO CELLS; CRICETINAE; CRICETULUS; HISTIDINE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; POINT MUTATION; PROTEIN FOLDING; SEQUENCE ALIGNMENT; SERINE; STEROL O-ACYLTRANSFERASE; TYROSINE;

EID: 51449089950     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M800131-JLR200     Document Type: Article

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