The molecular genetics of medulloblastoma: An assessment of new therapeutic targets

Neurosurgical Review

Volumn 31, Issue 4, 2008, Pages 359-368

  Carlotti Jr , Carlos G ^a   Smith, Christian ^b   Rutka, James T ^b  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Cyclopamine; Familial cancer syndromes; Hedgehog pathway; Medulloblastoma; Notch pathway; Wnt pathway

Indexed keywords

BENZIMIDAZOLE DERIVATIVE; CYCLOPAMINE; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; GEFITINIB; GROWTH FACTOR; HHANTAG; HISTONE DEACETYLASE INHIBITOR; NOTCH RECEPTOR; SONIC HEDGEHOG PROTEIN; SURVIVIN; UNCLASSIFIED DRUG; VALPROIC ACID; WNT PROTEIN;

BRAIN DEVELOPMENT; BRAIN TUMOR; CANCER GENETICS; CANCER SURVIVAL; CARCINOGENESIS; CELL DIFFERENTIATION; CELL MIGRATION; CHROMOSOME ABERRATION; CHROMOSOME REARRANGEMENT; COGNITION; COMPARATIVE GENOMIC HYBRIDIZATION; DNA MICROARRAY; DRUG ACTIVITY; DRUG BINDING; DRUG MECHANISM; DRUG MEGADOSE; DRUG TARGETING; EMBRYO DEVELOPMENT; FAMILIAL CANCER; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE MUTATION; GENETIC TRANSCRIPTION; GRANULE CELL; HUMAN; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LONG TERM CARE; LOW DRUG DOSE; MEDULLOBLASTOMA; MOLECULAR BIOLOGY; MOLECULAR GENETICS; NEUROENDOCRINOLOGY; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROGNOSIS; PROTEIN ANALYSIS; PROTEIN FUNCTION; PURKINJE CELL; REVIEW; RNA ANALYSIS; SIGNAL TRANSDUCTION; SURVIVAL RATE; SURVIVAL TIME;

BRAIN NEOPLASMS; HEDGEHOG PROTEINS; HUMANS; MEDULLOBLASTOMA; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; WNT PROTEINS;

EID: 51349102950     PISSN: 03445607     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10143-008-0146-4     Document Type: Review

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