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Volumn 47, Issue 6, 2008, Pages 1054-1061

Prognostic significance of numeric aberrations of genes for thymidylate synthase, thymidine phosphorylase and dihydrofolate reductase in colorectal cancer

Author keywords

[No Author keywords available]

Indexed keywords

DIHYDROFOLATE REDUCTASE; FLUOROURACIL; FOLINATE CALCIUM; PEPTIDE NUCLEIC ACID; THYMIDINE PHOSPHORYLASE; THYMIDYLATE SYNTHASE;

EID: 51149121463     PISSN: 0284186X     EISSN: 1651226X     Source Type: Journal    
DOI: 10.1080/02841860801942158     Document Type: Article
Times cited : (18)

References (25)
  • 1
    • 12444302837 scopus 로고    scopus 로고
    • Polymorphism in the thymidylate synthase promoter enhancer region is not an efficacious marker for tumor sensitivity to 5-fluorouracil-based oral adjuvant chemotherapy in colorectal cancer
    • Tsuji T, Hidaka S, Sawai T, Nakagoe T, Yano H, Haseba M, et al. Polymorphism in the thymidylate synthase promoter enhancer region is not an efficacious marker for tumor sensitivity to 5-fluorouracil-based oral adjuvant chemotherapy in colorectal cancer. Clin Cancer Res 2003;9:3700-4.
    • (2003) Clin Cancer Res , vol.9 , pp. 3700-3704
    • Tsuji, T.1    Hidaka, S.2    Sawai, T.3    Nakagoe, T.4    Yano, H.5    Haseba, M.6
  • 2
    • 0036534002 scopus 로고    scopus 로고
    • Investigation of the prognostic and predictive value of thymidylate synthase, p53, and Ki-67 in patients with locally advanced colon cancer
    • Allegra CJ, Parr AL, Wold LE, Mahoney MR, Sargent DJ, Johnston P, et al. Investigation of the prognostic and predictive value of thymidylate synthase, p53, and Ki-67 in patients with locally advanced colon cancer. J Clin Oncol 2002;20:1735-43.
    • (2002) J Clin Oncol , vol.20 , pp. 1735-1743
    • Allegra, C.J.1    Parr, A.L.2    Wold, L.E.3    Mahoney, M.R.4    Sargent, D.J.5    Johnston, P.6
  • 3
    • 33845691987 scopus 로고    scopus 로고
    • The prognostic significance of thymidylate synthase and dihydropyrimidine dehydrogenase in colorectal cancer of 303 patients adjuvantly treated with 5-fluorouracil
    • Jensen SA, Vainer B, Sorensen JB. The prognostic significance of thymidylate synthase and dihydropyrimidine dehydrogenase in colorectal cancer of 303 patients adjuvantly treated with 5-fluorouracil. Int J Cancer 2007;120:694-701.
    • (2007) Int J Cancer , vol.120 , pp. 694-701
    • Jensen, S.A.1    Vainer, B.2    Sorensen, J.B.3
  • 4
    • 0031722179 scopus 로고    scopus 로고
    • High basal level gene expression of thymidine phosphorylase (platelet-derived endothelial cell growth factor) in colorectal tumors is associated with nonresponse to 5-fluorouracil
    • Metzger R, Danenberg K, Leichman CG, Salonga D, Schwartz EL, Wadler S, et al. High basal level gene expression of thymidine phosphorylase (platelet-derived endothelial cell growth factor) in colorectal tumors is associated with nonresponse to 5-fluorouracil. Clin Cancer Res 1998;4:2371-6.
    • (1998) Clin Cancer Res , vol.4 , pp. 2371-2376
    • Metzger, R.1    Danenberg, K.2    Leichman, C.G.3    Salonga, D.4    Schwartz, E.L.5    Wadler, S.6
  • 5
    • 20244379716 scopus 로고    scopus 로고
    • Combined GADD45A and thymidine phosphorylase expression levels predict response and survival of neoadjuvant-treated gastric cancer patients
    • Napieralski R, Ott K, Kremer M, Specht K, Vogelsang H, Becker K, et al. Combined GADD45A and thymidine phosphorylase expression levels predict response and survival of neoadjuvant-treated gastric cancer patients. Clin Cancer Res 2005;11:3025-31.
    • (2005) Clin Cancer Res , vol.11 , pp. 3025-3031
    • Napieralski, R.1    Ott, K.2    Kremer, M.3    Specht, K.4    Vogelsang, H.5    Becker, K.6
  • 6
    • 0242658929 scopus 로고    scopus 로고
    • Both gene expression for orotate phosphoribosyltransferase and its ratio to dihydropyrimidine dehydrogenase influence outcome following fluoropyrimidine- based chemotherapy for metastatic colorectal cancer
    • Ichikawa W, Uetake H, Shirota Y, Yamada H, Takahashi T, Nihei Z, et al. Both gene expression for orotate phosphoribosyltransferase and its ratio to dihydropyrimidine dehydrogenase influence outcome following fluoropyrimidine- based chemotherapy for metastatic colorectal cancer. Br J Cancer 2003;89:1486-92.
    • (2003) Br J Cancer , vol.89 , pp. 1486-1492
    • Ichikawa, W.1    Uetake, H.2    Shirota, Y.3    Yamada, H.4    Takahashi, T.5    Nihei, Z.6
  • 7
    • 0034904368 scopus 로고    scopus 로고
    • p53, bcl-2 and thymidine phosphorylase as predictive markers of chemotherapy in patients with advanced and recurrent gastric cancer
    • Kikuyama S, Inada T, Shimizu K, Miyakita M, Ogata Y. p53, bcl-2 and thymidine phosphorylase as predictive markers of chemotherapy in patients with advanced and recurrent gastric cancer. Anticancer Res 2001;21:2149-53.
    • (2001) Anticancer Res , vol.21 , pp. 2149-2153
    • Kikuyama, S.1    Inada, T.2    Shimizu, K.3    Miyakita, M.4    Ogata, Y.5
  • 8
    • 0024237997 scopus 로고
    • Mechanisms for cisplatin-FUra synergism and cisplatin resistance in human ovarian carcinoma cells both in vitro and in vivo
    • Scanlon KJ, Lu Y, Kashani-Sabet M, Ma J, Newman E. Mechanisms for cisplatin-FUra synergism and cisplatin resistance in human ovarian carcinoma cells both in vitro and in vivo. Adv Exp Med Biol 1988;244:127-35.
    • (1988) Adv Exp Med Biol , vol.244 , pp. 127-135
    • Scanlon, K.J.1    Lu, Y.2    Kashani-Sabet, M.3    Ma, J.4    Newman, E.5
  • 9
    • 14944380124 scopus 로고    scopus 로고
    • Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphism in normal tissue as predictors of fluorouracil sensitivity
    • Jakobsen A, Nielsen JN, Gyldenkerne N, Lindeberg J. Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphism in normal tissue as predictors of fluorouracil sensitivity. J Clin Oncol 2005;23:1365-9.
    • (2005) J Clin Oncol , vol.23 , pp. 1365-1369
    • Jakobsen, A.1    Nielsen, J.N.2    Gyldenkerne, N.3    Lindeberg, J.4
  • 10
    • 15744388471 scopus 로고    scopus 로고
    • Common dihydrofolate reductase 19-base pair deletion allele: A novel risk factor for preterm delivery
    • Johnson WG, Scholl TO, Spychala JR, Buyske S, Stenroos ES, Chen X. Common dihydrofolate reductase 19-base pair deletion allele: A novel risk factor for preterm delivery. Am J Clin Nutr 2005;81:664-8.
    • (2005) Am J Clin Nutr , vol.81 , pp. 664-668
    • Johnson, W.G.1    Scholl, T.O.2    Spychala, J.R.3    Buyske, S.4    Stenroos, E.S.5    Chen, X.6
  • 11
    • 0034608950 scopus 로고    scopus 로고
    • Amplification of the human dihydrofolate reductase gene via double minutes is initiated by chromosome breaks
    • Singer MJ, Mesner LD, Friedman CL, Trask BJ, Hamlin JL. Amplification of the human dihydrofolate reductase gene via double minutes is initiated by chromosome breaks. Proc Natl Acad Sci USA 2000;97:7921-6.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 7921-7926
    • Singer, M.J.1    Mesner, L.D.2    Friedman, C.L.3    Trask, B.J.4    Hamlin, J.L.5
  • 12
    • 0842268401 scopus 로고    scopus 로고
    • Loss of heterozygosity at the thymidylate synthase (TS) locus on chromosome 18 affects tumor response and survival in individuals heterozygous for a 28-bp polymorphism in the TS gene
    • Uchida K, Hayashi K, Kawakami K, Schneider S, Yochim JM, Kuramochi H, et al. Loss of heterozygosity at the thymidylate synthase (TS) locus on chromosome 18 affects tumor response and survival in individuals heterozygous for a 28-bp polymorphism in the TS gene. Clin Cancer Res 2004;10:433-9.
    • (2004) Clin Cancer Res , vol.10 , pp. 433-439
    • Uchida, K.1    Hayashi, K.2    Kawakami, K.3    Schneider, S.4    Yochim, J.M.5    Kuramochi, H.6
  • 13
    • 27844583463 scopus 로고    scopus 로고
    • Expression levels of thymidine phosphorylase (TP) and dihydropyrimidine dehydrogenase (DPD) in patients with gastrointestinal cancer
    • Nakayama Y, Inoue Y, Nagashima N, Katsuki T, Matsumoto K, Kadowaki K, et al. Expression levels of thymidine phosphorylase (TP) and dihydropyrimidine dehydrogenase (DPD) in patients with gastrointestinal cancer. Anticancer Res 2005;25:3755-61.
    • (2005) Anticancer Res , vol.25 , pp. 3755-3761
    • Nakayama, Y.1    Inoue, Y.2    Nagashima, N.3    Katsuki, T.4    Matsumoto, K.5    Kadowaki, K.6
  • 14
    • 17644373059 scopus 로고    scopus 로고
    • Variance in the expression of 5-Fluorouracil pathway genes in colorectal cancer
    • Kidd EA, Yu J, Li X, Shannon WD, Watson MA, McLeod HL. Variance in the expression of 5-Fluorouracil pathway genes in colorectal cancer. Clin Cancer Res 2005;11:2612-9.
    • (2005) Clin Cancer Res , vol.11 , pp. 2612-2619
    • Kidd, E.A.1    Yu, J.2    Li, X.3    Shannon, W.D.4    Watson, M.A.5    McLeod, H.L.6
  • 15
    • 33847006971 scopus 로고    scopus 로고
    • Adjuvant chemotherapy in elderly patients (>or =75 yr) completely resected for colon cancer stage III compared to younger patients: Toxicity and prognosis
    • Jensen SA, Vilmar A, Sorensen JB. Adjuvant chemotherapy in elderly patients (>or =75 yr) completely resected for colon cancer stage III compared to younger patients: Toxicity and prognosis. Med Oncol 2006;23:521-31.
    • (2006) Med Oncol , vol.23 , pp. 521-531
    • Jensen, S.A.1    Vilmar, A.2    Sorensen, J.B.3
  • 16
    • 51149102361 scopus 로고    scopus 로고
    • Composition and methods for predicting outcome of treatment
    • Patent application WO2006128463
    • Nielsen KV, Ejlertsen BL, Poulsen TS, Mouridsen HT. Composition and methods for predicting outcome of treatment. Patent application WO2006128463 2006.
    • (2006)
    • Nielsen, K.V.1    Ejlertsen, B.L.2    Poulsen, T.S.3    Mouridsen, H.T.4
  • 17
    • 0036534108 scopus 로고    scopus 로고
    • Thymidylate synthase expression in colorectal cancer: A prognostic and predictive marker of benefit from adjuvant fluorouracil-based chemotherapy
    • Edler D, Glimelius B, Hallstrom M, Jakobsen A, Johnston PG, Magnusson I, et al. Thymidylate synthase expression in colorectal cancer: A prognostic and predictive marker of benefit from adjuvant fluorouracil-based chemotherapy. J Clin Oncol 2002;20:1721-8.
    • (2002) J Clin Oncol , vol.20 , pp. 1721-1728
    • Edler, D.1    Glimelius, B.2    Hallstrom, M.3    Jakobsen, A.4    Johnston, P.G.5    Magnusson, I.6
  • 18
    • 0028151449 scopus 로고
    • The role of thymidylate synthase expression in prognosis and outcome of adjuvant chemotherapy in patients with rectal cancer
    • Johnston PG, Fisher ER, Rockette HE, Fisher B, Wolmark N, Drake JC, et al. The role of thymidylate synthase expression in prognosis and outcome of adjuvant chemotherapy in patients with rectal cancer. J Clin Oncol 1994;12:2640-7.
    • (1994) J Clin Oncol , vol.12 , pp. 2640-2647
    • Johnston, P.G.1    Fisher, E.R.2    Rockette, H.E.3    Fisher, B.4    Wolmark, N.5    Drake, J.C.6
  • 19
    • 0032997572 scopus 로고    scopus 로고
    • Immunohistochemical quantitation of thymidylate synthase expression in colorectal cancer metastases predicts for clinical outcome to fluorouracil-based chemotherapy
    • Aschele C, Debernardis D, Casazza S, Antonelli G, Tunesi G, Baldo C, et al. Immunohistochemical quantitation of thymidylate synthase expression in colorectal cancer metastases predicts for clinical outcome to fluorouracil-based chemotherapy. J Clin Oncol 1999;17:1760-70.
    • (1999) J Clin Oncol , vol.17 , pp. 1760-1770
    • Aschele, C.1    Debernardis, D.2    Casazza, S.3    Antonelli, G.4    Tunesi, G.5    Baldo, C.6
  • 20
    • 23844476597 scopus 로고    scopus 로고
    • Thymidine phosphorylase expression and efficacy of adjuvant doxifluridine in advanced colorectal cancer patients
    • Hasegawa S, Seike K, Koda K, Takiguchi N, Oda K, Hasegawa R, et al. Thymidine phosphorylase expression and efficacy of adjuvant doxifluridine in advanced colorectal cancer patients. Oncol Rep 2005;13:621-6.
    • (2005) Oncol Rep , vol.13 , pp. 621-626
    • Hasegawa, S.1    Seike, K.2    Koda, K.3    Takiguchi, N.4    Oda, K.5    Hasegawa, R.6
  • 21
    • 25444489871 scopus 로고    scopus 로고
    • Immunohistochemical analysis of thymidylate synthase, thymidine phosphorylase, and dihydropyrimidine dehydrogenase in rectal cancer (cUICC II/III): Correlation with histopathologic tumor regression after 5-fluorouracil-based long-term neoadjuvant chemoradiotherapy
    • Jakob C, Liersch T, Meyer W, Baretton GB, Hausler P, Schwabe W, et al. Immunohistochemical analysis of thymidylate synthase, thymidine phosphorylase, and dihydropyrimidine dehydrogenase in rectal cancer (cUICC II/III): Correlation with histopathologic tumor regression after 5-fluorouracil-based long-term neoadjuvant chemoradiotherapy. Am J Surg Pathol 2005;29:1304-9.
    • (2005) Am J Surg Pathol , vol.29 , pp. 1304-1309
    • Jakob, C.1    Liersch, T.2    Meyer, W.3    Baretton, G.B.4    Hausler, P.5    Schwabe, W.6
  • 22
    • 9744250225 scopus 로고    scopus 로고
    • Thymidylate synthase, thymidine phosphorylase, dihydropyrimidine dehydrogenase expression, and histological tumour regression after 5-FU-based neo-adjuvant chemoradiotherapy in rectal cancer
    • Jakob C, Aust DE, Meyer W, Baretton GB, Schwabe W, Hausler P, et al. Thymidylate synthase, thymidine phosphorylase, dihydropyrimidine dehydrogenase expression, and histological tumour regression after 5-FU-based neo-adjuvant chemoradiotherapy in rectal cancer. J Pathol 2004;204:562-8.
    • (2004) J Pathol , vol.204 , pp. 562-568
    • Jakob, C.1    Aust, D.E.2    Meyer, W.3    Baretton, G.B.4    Schwabe, W.5    Hausler, P.6
  • 23
    • 0025318767 scopus 로고
    • Differential oncogene amplification in tumor cells from a patient treated with cisplatin and 5-fluorouracil
    • Kashani-Sabet M, Lu Y, Leong L, Haedicke K, Scanlon KJ. Differential oncogene amplification in tumor cells from a patient treated with cisplatin and 5-fluorouracil. Eur J Cancer 1990;26:383-90.
    • (1990) Eur J Cancer , vol.26 , pp. 383-390
    • Kashani-Sabet, M.1    Lu, Y.2    Leong, L.3    Haedicke, K.4    Scanlon, K.J.5
  • 24
    • 0034676235 scopus 로고    scopus 로고
    • Establishment and characterization of 5-fluorouracil-resistant gastric cancer cells
    • Chung YM, Park S, Park JK, Kim Y, Kang Y, Yoo YD. Establishment and characterization of 5-fluorouracil-resistant gastric cancer cells. Cancer Lett 2000;159:95-101.
    • (2000) Cancer Lett , vol.159 , pp. 95-101
    • Chung, Y.M.1    Park, S.2    Park, J.K.3    Kim, Y.4    Kang, Y.5    Yoo, Y.D.6
  • 25
    • 33750317308 scopus 로고    scopus 로고
    • Genomic copy number changes affecting the thymidylate synthase (TYMS) gene in cancer: A model for patient classification to aid fluoropyrimidine therapy
    • Brody JR, Hucl T, Gallmeier E, Winter JM, Kern SE, Murphy KM. Genomic copy number changes affecting the thymidylate synthase (TYMS) gene in cancer: A model for patient classification to aid fluoropyrimidine therapy. Cancer Res 2006;66:9369-73.
    • (2006) Cancer Res , vol.66 , pp. 9369-9373
    • Brody, J.R.1    Hucl, T.2    Gallmeier, E.3    Winter, J.M.4    Kern, S.E.5    Murphy, K.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.