Thymidylate synthase, thymidine phosphorylase, dihydropyrimidine dehydrogenase expression, and histological tumour regression after 5-FU-based neo-adjuvant chemoradiotherapy in rectal cancer

Journal of Pathology

Volumn 204, Issue 5, 2004, Pages 562-568

  Jakob, Christiane ^a   Aust, Daniela E ^a   Meyer, Wolfdietrich ^a   Baretton, Gustavo B ^a   Schwabe, Wolfgang ^c   Häusler, Peter ^c   Becker, Heinz ^b   Liersch, Torsten ^b  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^b UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^c Oncoscreen GmbH   (Germany)

Author keywords

DPD; Histological tumour regression; Microdissection; Neo adjuvant chemoradiotherapy; Rectal cancer; TP; TS

Indexed keywords

DIHYDROPYRIMIDINE DEHYDROGENASE; FLUOROURACIL; FORMALDEHYDE; PARAFFIN; THYMIDINE PHOSPHORYLASE; THYMIDYLATE SYNTHASE;

ADULT; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER ADJUVANT THERAPY; CANCER GRADING; CANCER RADIOTHERAPY; CANCER STAGING; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG RESPONSE; FEMALE; GENE EXPRESSION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LASER MICRODISSECTION; LONG TERM CARE; MALE; PREDICTION; PREOPERATIVE TREATMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RECTUM CANCER; RECTUM SURGERY; STATISTICAL SIGNIFICANCE; TUMOR BIOPSY; TUMOR REGRESSION;

ADENOCARCINOMA; ANTIMETABOLITES, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS; COMBINED MODALITY THERAPY; DIHYDROURACIL DEHYDROGENASE (NADP); FEMALE; FLUOROURACIL; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MIDDLE AGED; NEOPLASM STAGING; PREOPERATIVE CARE; PROGNOSIS; RECTAL NEOPLASMS; RNA, MESSENGER; RNA, NEOPLASM; THYMIDINE PHOSPHORYLASE; THYMIDYLATE SYNTHASE;

EID: 9744250225     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/path.1663     Document Type: Article

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