Immunohistochemical analysis of thymidylate synthase, thymidine phosphorylase, and dihydropyrimidine dehydrogenase in rectal cancer (cUICC II/III): Correlation with histopathologic tumor regression after 5-fluorouracil-based long-term neoadjuvant chemorodiotheropy

American Journal of Surgical Pathology

Volumn 29, Issue 10, 2005, Pages 1304-1309

  Jakob, Christiane ^a,d   Liersch, Torsten ^b   Meyer, Wolfdietrich ^a   Baretton, Gustavo B ^a   Häusler, Peter ^c   Schwabe, Wolfgang ^c   Becker, Heinz ^b   Aust, Daniela E ^a  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^b UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^c Oncoscreen GmbH   (Germany)

^d Institut Für Pathologie   (Germany)

Author keywords

DPD; Histopathologic tumor regression; Rectal cancer; TP; TS

Indexed keywords

BIOLOGICAL MARKER; DIHYDROPYRIMIDINE DEHYDROGENASE; FLUOROURACIL; MESSENGER RNA; THYMIDINE PHOSPHORYLASE; THYMIDYLATE SYNTHASE;

ADJUVANT CHEMOTHERAPY; ADULT; ADVANCED CANCER; ARTICLE; CANCER CHEMOTHERAPY; CANCER CONTROL; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER REGRESSION; CANCER STAGING; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LONG TERM CARE; MALE; OUTCOMES RESEARCH; POSTOPERATIVE PERIOD; PREDICTION; PREOPERATIVE TREATMENT; PROTEIN EXPRESSION; RECTUM CARCINOMA; RECTUM RESECTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCORING SYSTEM; TECHNIQUE; TUMOR BIOPSY;

ANTIMETABOLITES, ANTINEOPLASTIC; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; COMBINED MODALITY THERAPY; DIHYDROURACIL DEHYDROGENASE (NADP); FEMALE; FLUOROURACIL; GENE EXPRESSION PROFILING; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; NEOADJUVANT THERAPY; NEOPLASM STAGING; RECTAL NEOPLASMS; THYMIDINE PHOSPHORYLASE; THYMIDYLATE SYNTHASE; TREATMENT OUTCOME; TUMOR MARKERS, BIOLOGICAL;

EID: 25444489871     PISSN: 01475185     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.pas.0000170346.55304.88     Document Type: Article

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