Space-time considerations for hematopoietic stem cell transplantation

European Journal of Immunology

Volumn 38, Issue 8, 2008, Pages 2060-2067

  Bhattacharya, Deepta ^a,b   Richie Ehrlich, Lauren I ^a   Weissman, Irving L ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY   (United States)

Author keywords

Common lymphoid progenitor; Common myeloid progenitor; Hematopoietic stem cell; Immune reconstitution; Transplantation

Indexed keywords

ALKYLATING AGENT; FLUOROURACIL; IMMUNOSUPPRESSIVE AGENT;

ANEMIA; AUTOIMMUNITY; BLOOD DISEASE; BONE MARROW TRANSPLANTATION; CELL LINEAGE; CHIMERA; DNA DAMAGE; DONOR; DRUG EFFICACY; DRUG SAFETY; EXPERIMENTAL MODEL; GENE MUTATION; GRAFT REJECTION; GRAFT VERSUS HOST REACTION; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; IMMUNOCOMPETENCE; LYMPHOID CELL; MONOTHERAPY; MYELOABLATIVE CONDITIONING; NONHUMAN; OPPORTUNISTIC INFECTION; PHENOTYPE; PRIORITY JOURNAL; RECIPIENT; REDUCED INTENSITY CONDITIONING; SEVERE COMBINED IMMUNODEFICIENCY; SHORT SURVEY; T LYMPHOCYTE; UNSPECIFIED SIDE EFFECT; ANIMAL; CYTOLOGY; HEMATOPOIETIC STEM CELL; IMMUNOLOGY; IMMUNOPHENOTYPING; IMMUNOSUPPRESSIVE TREATMENT; REVIEW;

ANIMALS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; HUMANS; IMMUNOPHENOTYPING; T-LYMPHOCYTES; TRANSPLANTATION CONDITIONING;

EID: 51149097393     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200838383     Document Type: Short Survey

References (68)

1. Morrison, S. J. and Spradling, A. C., Stem cells and niches: Mechanisms that promote stem cell maintenance throughout life. Cell 2008. 132: 598-611.
2. Wright, D. E., Wagers, A. J., Gulati, A. P., Johnson, F. L. and Weissman, I. L., Physiological migration of hematopoietic stem and progenitor cells. Science 2001. 294: 1933-1936.
3. Massberg, S., Schaerli, P., Knezevic-Maramica, I., Kollnberger, M., Tubo, N., Moseman, E. A., Huff, I. V. et al., Immunosurveillance by hematopoietic progenitor cells trafficking through blood, lymph, and peripheral tissues. Cell 2007. 131: 994-1008.
4. Liles, W. C., Broxmeyer, H. E., Rodger, E., Wood, B., Hubel, K., Cooper, S., Hangoc, G. et al., Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD3100, a CXCR4 antagonist. Blood 2003. 102: 2728-2730.
5. Molineux, G., Pojda, Z., Hampson, I. N., Lord, B. I. and Dexter, T. M., Transplantation potential of peripheral blood stem cells induced by granulocyte colony-stimulating factor. Blood 1990. 76: 2153-2158.
6. + hematopoietic stem cells in patients with metastatic breast cancer. Biol. Blood Marrow Transplant. 2000. 6: 262-271.
7. Osawa, M., Hanada, K., Hamada, H. and Nakauchi, H., Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell. Science 1996. 273: 242-245.
8. Majeti, R., Park, C. Y. and Weissman, I. L., Identification of a hierarchy of multipotent hematopoietic progenitors in human cord blood. Cell Stem Cell 2007. 1: 635-645.
9. Shlomchik, W. D., Graft-versus-host disease. Nat. Rev. Immunol. 2007. 7: 340-352.
10. Riddell, S. R. and Appelbaum, F. R., Graft-versus-host disease: A surge of developments. PLoS Med. 2007. 4: e198.
11. Micklem, H. S., Clarke, C. M., Evans, E. P. and Ford, C. E., Fate of chromosome-marked mouse bone marrow cells transfused into normal syngeneic recipients. Transplantation 1968. 6: 299-302.
12. Brecher, G., Ansell, J. D., Micklem, H. S., Tjio, J. H. and Cronkite, E. P., Special proliferative sites are not needed for seeding and proliferation of transfused bone marrow cells in normal syngeneic mice. Proc. Natl. Acad. Sci. USA 1982. 79: 5085-5087.
13. Saxe, D. F., Boggs, S. S. and Boggs, D. R., Transplantation of chromosomally marked syngeneic marrow cells into mice not subjected to hematopoietic stem cell depletion. Exp. Hematol. 1984. 12: 277-283.
14. Stewart, F. M., Crittenden, R. B., Lowry, P. A., Pearson-White, S. and Quesenberry, P. J., Long-term engraftment of normal and post-5-fluorouracil murine marrow into normal nonmyeloablated mice. Blood 1993. 81: 2566-2571.
15. Wu, D. D. and Keating, A., Hematopoietic stem cells engraft in untreated transplant recipients. Exp. Hematol. 1993. 21: 251-256.
16. Gambel, P., Francescutti, L. H. and Wegmann, T. G., Antibody-facilitated chimeras. Stem cell allotransplantation using antihost major histocompatibility complex monoclonal antibodies instead of lethal irradiation for host conditioning. Transplantation 1984. 38: 152-158.
17. Visser, J.W., Bauman, J. G., Mulder, A. H., Eliason, J. F. and de Leeuw, A. M., Isolation of murine pluripotent hemopoietic stem cells. J. Exp. Med. 1984. 159: 1576-1590.
18. Bhattacharya, D., Rossi, D. J., Bryder, D. and Weissman, I. L., Purified hematopoietic stem cell engraftment of rare niches corrects severe lymphoid deficiencies without host conditioning. J. Exp. Med. 2006. 203: 73-85.
19. Czechowicz, A., Kraft, D., Weissman, I. L. and Bhattacharya, D., Efficient transplantation via antibody-based clearance of hematopoietic stem cell niches. Science 2007. 318: 1296-1299.
20. Gatti, R. A., Meuwissen, H. J., Allen, H. D., Hong, R. and Good, R. A., Immunological reconstitution of sex-linked lymphopenic immunological deficiency. Lancet 1968. 2: 1366-1369.
21. Muller, S. M., Kohn, T., Schulz, A. S., Debatin, K. M. and Friedrich, W., Similar pattern of thymic-dependent T-cell reconstitution in infants with severe combined immunodeficiency after human leukocyte antigen (HLA)-identical and HLA-nonidentical stem cell transplantation. Blood 2000. 96: 4344-4349.
22. Rossi, D. J., Seita, J., Czechowicz, A., Bhattacharya, D., Bryder, D. and Weissman, I. L., Hematopoietic stem cell quiescence attenuates DNA damage response and permits DNA damage accumulation during aging. Cell Cycle 2007. 6: 2371-2376.
23. Cavazzana-Calvo, M., Carlier, F., Le Deist, F., Morillon, E., Taupin, P., Gautier, D., Radford-Weiss, I. et al., Long-term T-cell reconstitution after hematopoietic stem-cell transplantation in primary T-cell-immunodeficient patients is associated with myeloid chimerism and possibly the primary disease phenotype. Blood 2007. 109: 4575-4581.
24. Antoine, C., Muller, S., Cant, A., Cavazzana-Calvo, M., Veys, P., Vossen, J., Fasth, A. et al., Long-term survival and transplantation of haemopoietic stem cells for immunodeficiencies: Report of the European experience 1968-99. Lancet 2003. 361: 553-560.
25. Borghans, J. A., Bredius, R. G., Hazenberg, M. D., Roelofs, H., Jol-van der Zijde, E. C., Heidt, J., Otto, S. A. et al., Early determinants of long-term T-cell reconstitution after hematopoietic stem cell transplantation for severe combined immunodeficiency. Blood 2006. 108: 763-769.
26. Sarzotti, M., Patel, D. D., Li, X., Ozaki, D. A., Cao, S., Langdon, S., Parrott, R. E. et al., T cell repertoire development in humans with SCID after nonablative allogeneic marrow transplantation. J. Immunol. 2003. 170: 2711-2718.
27. Copelan, E. A., Conditioning regimens for allogeneic bone marrow transplantation. Blood Rev. 1992. 6: 234-242.
28. Yoshihara, H., Arai, F., Hosokawa, K., Hagiwara, T., Takubo, K., Nakamura, Y., Gomei, Y. et al., Thrombopoietin/MPL signaling regulates hematopoietic stem cell quiescence and interaction with the osteoblastic niche. Cell Stem Cell 2007. 1: 685-697.
29. Howard, J. G. and Woodruff, M. F. A., Effect of the graft- versus-host reaction on the immunological responsiveness of the mouse. Proc. Roy. Soc. 1961. 154: 532-539.
30. Sprent, J. and Miller, J. F., Effect of recent antigen priming on adoptive immune responses. III. Antigen-induced selective recruitment of subsets of recirculating lymphocytes reactive to H-2 determinants. J. Exp. Med. 1976. 143: 585-600.
31. Keever, C. A., Flomenberg, N., Brochstein, J., Sullivan, M., Collins, N. H., Burns, J., Dupont, B. and O'Reilly, R. J., Tolerance of engrafted donor T cells following bone marrow transplantation for severe combined immunodeficiency. Clin. Immunol. Immunopathol. 1988. 48: 261-276.
32. Roncarolo, M. G., Bacchetta, R., Bigler, M., Touraine, J. L., de Vries, J. E. and Spits, H., A SCID patient reconstituted with HLA-incompatible fetal stem cells as a model for studying transplantation tolerance. Blood Cells 1991. 17: 391-402.
33. Shizuru, J. A., Jerabek, L., Edwards, C. T. and Weissman, I. L., Transplantation of purified hematopoietic stem cells: Requirements for overcoming the barriers of allogeneic engraftment. Biol. Blood Marrow Transplant. 1996. 2: 3-14.
34. Arber, C., BitMansour, A., Sparer, T. E., Higgins, J. P., Mocarski, E. S., Weissman, I. L., Shizuru, J. A. and Brown, J. M., Common lymphoid progenitors rapidly engraft and protect against lethal murine cytomegalo-virus infection after hematopoietic stem cell transplantation. Blood 2003. 102: 421-428.
35. Akashi, K., Traver, D., Miyamoto, T. and Weissman, I. L., A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature 2000. 404: 193-197.
36. Terszowski, G., Waskow, C., Conradt, P., Lenze, D., Koenigsmann, J., Carstanjen, D., Horak, I. and Rodewald, H. R., Prospective isolation and global gene expression analysis of the erythrocyte colony-forming unit (CFU-E). Blood 2005. 105: 1937-1945.
37. Nutt, S. L., Metcalf, D., D'Amico, A., Polli, M. and Wu, L., Dynamic regulation of PU.1 expression in multipotent hematopoietic progenitors. J. Exp. Med. 2005. 201: 221-231.
38. Yoshida, T., Ng, S. Y., Zuniga-Pflucker, J. C. and Georgopoulos, K., Early hematopoietic lineage restrictions directed by Ikaros. Nat. Immunol. 2006. 7: 382-391.
39. Pronk, C. J. H., Rossi, D. J., Mansson, R., Attema, J. L., Norddahl, G. L., Chan, C. K. F., Sigvardsson, M. et al., Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy. Cell Stem Cell 2007. 1: 428-442.
40. Arinobu, Y., Mizuno, S., Chong, Y., Shigematsu, H., Iino, T., Iwasaki, H., Graf, T. et al., Reciprocal activation of GATA-1 and PU.1 marks initial specification of hematopoietic stem cells into myeloerythroid and myelolymphoid lineages. Cell Stem Cell 2007. 1: 416-427.
41. Manz, M. G., Miyamoto, T., Akashi, K. and Weissman, I. L., Prospective isolation of human clonogenic common myeloid progenitors. Proc. Natl. Acad. Sci. USA 2002. 99: 11872-11877.
42. BitMansour, A., Burns, S. M., Traver, D., Akashi, K., Contag, C. H., Weissman, I. L. and Brown, J. M., Myeloid progenitors protect against invasive aspergillosis and Pseudomonas aeruginosa infection following hematopoietic stem cell transplantation. Blood 2002. 100: 4660-4667.
43. BitMansour, A., Cao, T. M., Chao, S., Shashidhar, S. and Brown, J. M., Single infusion of myeloid progenitors reduces death from Aspergillus fumigatus following chemotherapy-induced neutropenia. Blood 2005. 105: 3535-3537.
44. Arber, C., BitMansour, A., Shashidhar, S., Wang, S., Tseng, B. and Brown, J. M., Protection against lethal Aspergillus fumigatus infection in mice by allogeneic myeloid progenitors is not major histocompatibility complex restricted. J. Infect. Dis. 2005. 192: 1666-1671.
45. Donskoy, E. and Goldschneider, I., Thymocytopoiesis is maintained by blood-borne precursors throughout postnatal life. A study in parabiotic mice. J. Immunol. 1992. 148: 1604-1612.
46. Kondo, M., Weissman, I. L. and Akashi, K., Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell 1997. 91: 661-672.
47. Zakrzewski, J. L., Kochman, A. A., Lu, S. X., Terwey, T. H., Kim, T. D., Hubbard, V. M., Muriglan, S. J. et al., Adoptive transfer of T-cell precursors enhances T-cell reconstitution after allogeneic hematopoietic stem cell transplantation. Nat. Med. 2006. 12: 1039-1047.
48. Allman, D., Sambandam, A., Kim, S., Miller, J. P., Pagan, A., Well, D., Meraz, A. and Bhandoola, A., Thymopoiesis independent of common lymphoid progenitors. Nat. Immunol. 2003. 4: 168-174.
49. Lai, A. Y. and Kondo, M., Identification of a bone marrow precursor of the earliest thymocytes in adult mouse. Proc. Natl. Acad. Sci. USA 2007. 104: 6311-6316.
50. Perry, S. S., Welner, R. S., Kouro, T., Kincade, P. W. and Sun, X. H., Primitive lymphoid progenitors in bone marrow with T lineage reconstituting potential. J. Immunol. 2006. 177: 2880-2887.
51. Schwarz, B. A., Sambandam, A., Maillard, I., Harman, B. C., Love, P. E. and Bhandoola, A., Selective thymus settling regulated by cytokine and chemokine receptors. J. Immunol. 2007. 178: 2008-2017.
52. Bell, J. J. and Bhandoola, A., The earliest thymic progenitors for T cells possess myeloid lineage potential. Nature 2008. 452: 764-767.
53. Wada, H., Masuda, K., Satoh, R., Kakugawa, K., Ikawa, T., Katsura, Y. and Kawamoto, H., Adult T-cell progenitors retain myeloid potential. Nature 2008. 452: 768-772.
54. Krueger, A., Garbe, A. I. and von Boehmer, H., Phenotypic plasticity of T cell progenitors upon exposure to Notch ligands. J. Exp. Med. 2006. 203: 1977-1984.
55. + common lymphoid progenitors possess equivalent differentiation potential for the B and T lineages. Blood 2008. 111: 5562-5570.
56. Igarashi, H., Gregory, S. C., Yokota, T., Sakaguchi, N. and Kincade, P.W., Transcription from the RAG1 locus marks the earliest lymphocyte progenitors in bone marrow. Immunity 2002. 17: 117-130.
57. Izon, D., Rudd, K., DeMuth, W., Pear, W. S., Clendenin, C., Lindsley, R. C. and Allman, D., A common pathway for dendritic cell and early B cell development. J. Immunol. 2001. 167: 1387-1392.
58. Bhandoola, A., von Boehmer, H., Petrie, H. T. and Zuniga-Pflucker, J. C., Commitment and developmental potential of extrathymic and intrathymic T cell precursors: Plenty to choose from. Immunity 2007. 26: 678-689.
59. Manz, M. G., Traver, D., Miyamoto, T., Weissman, I. L. and Akashi, K., Dendritic cell potentials of early lymphoid and myeloid progenitors. Blood 2001. 97: 3333-3341.
60. Matsuzaki, Y., Gyotoku, J., Ogawa, M., Nishikawa, S., Katsura, Y., Gachelin, G. and Nakauchi, H., Characterization of c-kit positive intrathymic stem cells that are restricted to lymphoid differentiation. J. Exp. Med. 1993. 178: 1283-1292.
61. Mori, S., Shortman, K. and Wu, L., Characterization of thymus-seeding precursor cells from mouse bone marrow. Blood 2001. 98: 696-704.
62. King, A. G., Kondo, M., Scherer, D. C. and Weissman, I. L., Lineage infidelity in myeloid cells with TCR gene rearrangement: A latent developmental potential of proT cells revealed by ectopic cytokine receptor signaling. Proc. Natl. Acad. Sci. USA 2002. 99: 4508-4513.
63. Galy, A., Travis, M., Cen, D. and Chen, B., Human T, B, natural killer, and dendritic cells arise from a common bone marrow progenitor cell subset. Immunity 1995. 3: 459-473.
64. Hao, Q. L., Zhu, J., Price, M. A., Payne, K. J., Barsky, L. W. and Crooks, G. M., Identification of a novel, human multilymphoid progenitor in cord blood. Blood 2001. 97: 3683-3690.
65. Haddad, R., Guardiola, P., Izac, B., Thibault, C., Radich, J., Delezoide, A. L., Baillou, C. et al., Molecular characterization of early human T/NK and B-lymphoid progenitor cells in umbilical cord blood. Blood 2004. 104: 3918-3926.
66. Six, E. M., Bonhomme, D., Monteiro, M., Beldjord, K., Jurkowska, M., Cordier-Garcia, C., Garrigue, A. et al., A human postnatal lymphoid progenitor capable of circulating and seeding the thymus. J. Exp. Med. 2007. 204: 3085-3093.
67. Thomas, E. D., Lochte, H. L., Jr., Lu, W. C. and Ferrebee, J. W., Intravenous infusion of bone marrow in patients receiving radiation and chemotherapy. N. Engl. J. Med. 1957. 257: 491-496.
68. Copelan, E. A., Hematopoietic stem-cell transplantation. N. Engl. J. Med. 2006. 354: 1813-1826.