Similar pattern of thymic-dependent T-cell reconstitution in infants with serve combined immunodeficiency after human leukocyte antigen (HLA)-identical and HLA-nonidentical stem cell transplantation

Blood

Volumn 96, Issue 13, 2000, Pages 4344-4349

  Muller, Susanna M ^a   Kohn, Thomas ^a   Schulz, Ansgar S ^a   Debalin, Klaus Michael ^a   Friedrich, Wilhelim ^a  

^a UNIVERSITY HOSPITAL ULM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CD45 ANTIGEN; GRANULOCYTE COLONY STIMULATING FACTOR; HLA ANTIGEN;

ADOLESCENT; ADULT; ARTICLE; CD4+ T LYMPHOCYTE; CHILD; CHIMERA; COMBINED IMMUNODEFICIENCY; CYTOLOGY; ECHOGRAPHY; FEMALE; GENETICS; GRAFT SURVIVAL; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HISTOCOMPATIBILITY; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INFANT; MALE; PRESCHOOL CHILD; T LYMPHOCYTE SUBPOPULATION; THYMUS; TIME;

ADOLESCENT; ADULT; ANTIGENS, CD45; CD4-POSITIVE T-LYMPHOCYTES; CHILD; CHILD, PRESCHOOL; CHIMERA; FEMALE; GRAFT SURVIVAL; GRANULOCYTE COLONY-STIMULATING FACTOR; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HISTOCOMPATIBILITY; HLA ANTIGENS; HUMANS; INFANT; MALE; SEVERE COMBINED IMMUNODEFICIENCY; T-LYMPHOCYTE SUBSETS; THYMUS GLAND; TIME FACTORS; TRANSPLANTATION CONDITIONING;

EID: 0034672163     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v96.13.4344     Document Type: Article

References (19)

1. Mackall CL, Granger L, Sheard MA, Cepeda R, Gress RE. T-cell regeneration after bone marrow transplantation: differential CD45 isoform expression in thymic-derived versus thymic-independent progeny. Blood. 1993;82:2585-2585.
2. Mackall CL, Gress RE. Pathways of T-cell regeneration in mice and humans: implications for bone marrow transplantation and immunotherapy. Immunol Rev. 1997;157:61-72.
3. + T-cell "memory," CD45R subsets and the persistence of antigen - a unifying concept. Immunol Today. 1998;19:60-64.
4. Fischer A, Cavazzana-Calvo M, De Saint-Basile G, et al. Naturally occurring primary deficiencies of the immune system. Annu Rev Immunol. 1997;15:93-124.
5. Friedrich W, Goldmann SF, Vetter U, et al. Immunoreconstitution in severe combined immunodeficiency after transplantation of HLA-haploidentical, T-cell-depleted bone marrow. Lancet. 1984;1:761-764.
6. Buckley RH, Schiff SE, Schiff RI, et al. Hemato-poietic stem cell transplantation for the treatment of severe combined immunodeficiency. N Engl J Med. 1999;340:508-516.
7. Van Leeuwen JE, van Toi MJ, Joosten AM, et al. Relationship between patterns of engraftment in peripheral blood and immune reconstitution after allogeneic bone marrow transplantation for (severe) combined immunodeficiency. Blood. 1994;84:3936-3947.
8. Schreiner T, Wiesneth M, Slaper-Cortenbach I, et al. Improved lectin agglutination method for T-cell depletion of HLA-mismatched bone marrow grafts in children. Transfus Sci. 1996;17:637-642.
9. Wiesneth W, Schreiner T, Friedrich W, et al. Combined CD34 positive plus CD2 negative selection for effective T-cell depletion as GvHD-prophylaxis in HLA-nonidentical blood progenitor cell transplantation. Transfus Sci. 1996;17:629-635.
10. Knobloch C, Goldmann SF, Lattke H, Friedrich W. Stable engraftment of allogeneic T-lymphocytes in a patient with severe combined immunodeficiency following a transfusion with unirradiated blood: specific recognition of host histocompat-ibility antigens and engraftment failure of a bone marrow transplant HLA-identical to the host. Transplantation. 1991;51:818-824.
11. Lemaitre L, Marconi V, Avni F, Remy J. The sonographic evaluation of normal thymus in infants and children. Eur J Radiol. 1987;7:130-136.
12. Weinberg K, Annett G, Kashyap A, Lenarsky C, Forman SJ, Parkman R. The effect of thymic function on immunocompetence following bone marrow transplantation. Biol Blood Marrow Transplant. 1995;1:18-23.
13. Storek J, Witherspoon RP, Storb R. T cell reconstitution after bone marrow transplantation into adult patients does not resemble T cell development in early life. Bone Marrow Transplant. 1995;16:413-425.
14. Lowdell MW. Craston R, Ray N, Koh M, Galatowicz G, Prentice HG. The effect of T cell depletion with Campath-1M on immune reconstitution after chemotherapy and allogeneic bone marrow transplant as treatment for leukaemia. Bone Marrow Transplant. 1998;21:679-686.
15. Dumont-Girard F, Roux E, van Lier RA, et at. Reconstitution of the T-cell compartment after bone marrow transplantation: restoration of the repertoire by thymic emigrants. Blood. 1998;11:4464-4471.
16. Mackall CL, Gress RE. Thymic aging and T cell regeneration. Immunol Rev. 1997;160:91-102.
17. Mackall CL, Punt JA, Morgan P, Farr AG, Gress RE. Thymic function in young/old chimeras: substantial thymic T cell regenerative capacity despite irreversible age-associated thymic involution. Eur J Immunol. 1998;28:1886-1893.
18. Randle-Barrett ES, Boyd RL. Thymic microenvironment and lymphoid responses to sublethal irradiation. Dev Immunol. 1995;4:101-116.
19. Fukushi N, Arase H, Wang B, et al. Thymus: a direct target tissue in graft-versus-host reaction after allogeneic bone marrow transplantation that results in abrogation of induction of self tolerance. Proc Natl Acad Sci USA. 1990;87:6301-6305.