Primitive lymphoid progenitors in bone marrow with T lineage reconstituting potential

Journal of Immunology

Volumn 177, Issue 5, 2006, Pages 2880-2887

  Perry, S Scott ^a   Welner, Robert S ^a,b   Kouro, Taku ^a   Kincade, Paul W ^a   Sun, Xiao Hong ^a  

^a OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

^b UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GREEN FLUORESCENT PROTEIN; PADGEM PROTEIN; RAG1 PROTEIN; STEM CELL FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CELL LINEAGE; LYMPHOID CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; STEM CELL; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION; THYMOCYTE; THYMUS; TISSUE REGENERATION;

EID: 33747781772     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.177.5.2880     Document Type: Article

References (58)

1. Scollay, R., J. Smith, and V. Stauffer. 1986. Dynamics of early T cells: prothymocyte migration and proliferation in the adult mouse thymus. Immunol. Rev. 91: 129-157.
2. Foss, D. L., E. Donskoy, and I. Goldschneider. 2001. The importation of hematogenous precursors by the thymus is a gated phenomenon in normal adult mice. J. Exp. Med. 193: 365-374.
3. Bhandoola, A., and A. Sambandam. 2006. From stem cell to T cell: one route or many? Nat. Rev. Immunol. 6: 117-126.
4. Huang, J., K. P. Garrett, R. Pelayo, J. C. Zúñiga- Pflücker, H. T. Petrie, and P. W. Kincade. 2005. Propensity of adult lymphoid progenitors to progress to DN2/3 stage thymocytes with Notch receptor ligation. J. Immunol. 175: 4858-4865.
5. Balciunaite, G., R. Ceredig, H. J. Fehling, J. C. Zúñiga- Pflücker, and A. G. Rolink. 2005. The role of Notch and IL-7 signaling in early thymocyte proliferation and differentiation. Eur. J. Immunol. 35: 1292-1300.
6. Balciunaite, G., R. Ceredig, and A. G. Rolink. 2005. The earliest subpopulation of mouse thymocytes contains potent T, significant macrophage, and natural killer cell but no B-lymphocyte potential. Blood 105: 1930-1936.
7. Pelayo, R., R. Welner, S. S. Perry, J. Huang, Y. Baba, T. Yokota, and P. W. Kincade. 2005. Lymphoid progenitors and primary routes to becoming cells of the immune system. Curr. Opin. Immunol. 17: 100-107.
8. Pear, W. S., L. Tu, and P. L. Stein. 2004. Lineage choices in the developing thymus: choosing the T and NKT pathways. Curr. Opin. Immunol. 16: 167-173.
9. Bhandoola, A., A. Sambandam, D. Allman, A. Meraz, and B. Schwarz. 2003. Early T lineage progenitors: new insights, but old questions remain. J. Immunol. 171: 5653-5658.
10. Morrison, S. J., D. E. Wright, and I. L. Weissman. 1997. Cyclophosphamide/granulocyte colony-stimulating factor induces hematopoietic stem cells to proliferate prior to mobilization. Proc. Natl. Acad. Sci. USA 94: 1908-1913.
11. Schwarz, B. A., and A. Bhandoola. 2004. Circulating hematopoietic progenitors with T lineage potential. Nat. Immunol. 5: 953-960.
12. Perry, S. S., L. J. Pierce, W. B. Slayton, and G. J. Spangrude. 2003. Characterization of thymic progenitors in adult mouse bone marrow. J. Immunol. 170: 1877-1886.
13. Spangrude, G. J., and R. Scollay. 1990. Differentiation of hematopoietic stem cells in irradiated mouse thymic lobes: kinetics and phenotype of progeny. J. Immunol. 145: 3661-3668.
14. Porritt, H. E., L. L. Rumfelt, S. Tabrizifard, T. M. Schmitt, J. C. Zúñiga-Pflücker, and H. T. Petrie. 2004. Heterogeneity among DN1 prothymocytes reveals multiple progenitors with different capacities to generate T cell and non-T cell lineages. Immunity 20: 735-745.
15. Sambandam, A., I. Maillard, V. P. Zediak, L. Xu, R. M. Gerstein, J. C. Aster, W. S. Pear, and A. Bhandoola. 2005. Notch signaling controls the generation and differentiation of early T lineage progenitors. Nat. Immunol. 6: 663-670.
16. Perry, S. S., H. Wang, L. J. Pierce, A. M. Yang, S. Tsai, and G. J. Spangrude. 2004. L-Selectin defines a bone marrow analog to the thymic early T-lineage progenitor. Blood 103: 2990-2996.
17. Medina, K. L., K. P. Garrett, L. F. Thompson, M. I. D. Rossi, K. J. Payne, and P. W. Kincade. 2001. Identification of very early lymphoid precursors in bone marrow and their regulation by estrogen. Nat. Immunol. 2: 718-724.
18. Igarashi, H., S. C. Gregory, T. Yokota, N. Sakaguchi, and P. W. Kincade. 2002. Transcription from the RAG1 locus marks the earliest lymphocyte progenitors in bone marrow. Immunity 17: 117-130.
19. + lympho-myeloid stem cells lacking erythro-megakaryocytic potential: a revised road map for adult blood lineage commitment. Cell 121: 295-306.
20. 3-expressing multipotent progenitors in mouse bone marrow. J. Immunol. 175: 5016-5023.
21. Searles, A. E., S. J. Pohlmann, L. J. Pierce, S. S. Perry, W. B. Slayton, M. P. Mojica, and G. J. Spangrude. 2000. Rapid, B lymphoid-restricted engraftment mediated by a primitive bone marrow subpopulation. J. Immunol. 165: 67-74.
22. Mojica, M. P., S. S. Perry, A. E. Searles, K. S. Elenitoba-Johnson, L. J. Pierce, A. Wiesmann, W. B. Slayton, and G. J. Spangrude. 2001. Phenotypic distinction and functional characterization of pro-B cells in adult mouse bone marrow. J. Immunol. 166: 3042-3051.
23. Kondo, M., I. L. Weissman, and K. Akashi. 1997. Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell 91: 661-672.
24. Allman, D., A. Sambandam, S. Kim, J. P. Miller, A. Pagan, D. Well, A. Meraz, and A. Bhandoola. 2003. Thymopoiesis independent of common lymphoid progenitors. Nat. Immunol. 4: 168-174.
25. Benz, C., and C. C. Bleul. 2005. A multipotent precursor in the thymus maps to the branching point of the T versus B lineage decision. J. Exp. Med. 202: 21-31.
26. Benz, C., K. Heinzel, and C. C. Bleul. 2004. Homing of immature thymocytes to the subcapsular microenvironment within the thymus is not an absolute requirement for T cell development. Eur. J. Immunol. 34: 3652-3663.
27. Gounari, F., I. Aifantis, C. Martin, H. J. Fehling, S. Hoeflinger, P. Leder, H. Von Boehmer, and B. Reizis. 2002. Tracing lymphopoiesis with the aid of a pTα-controlled reporter gene. Nat. Immunol. 3: 489-496.
28. + lymphoid-restricted bone marrow cells with T precursor potential. Nat. Immunol. 4: 866-873.
29. - precursors. Nature 303: 248-250.
30. Pearse, M., L. Wu, M. Egerton, A. Wilson, K. Shortman, and R. Scollay. 1989. A murine early thymocyte developmental sequence is marked by transient expression of the interleukin 2 receptor. Proc. Natl. Acad. Sci. USA 86: 1614-1618.
31. Fowlkes, B. J., L. Edison, B. J. Mathieson, and T. M. Chused. 1985. Early T lymphocytes: differentiation in vivo of adult intrathymic precursor cells. J. Exp. Med. 162: 802-822.
32. - triple-negative adult mouse thymocytes defined by CD44 and CD25 expression. J. Immunol. 150: 4244-4252.
33. Ceredig, R., and T. Rolink. 2002. A positive look at double-negative thymocytes. Nat. Rev. Immunol. 2: 888-897.
34. Laurent, J., N. Bosco, P. N. Marche, and R. Ceredig. 2004. New insights into the proliferation and differentiation of early mouse thymocytes. Int. Immunol. 16: 1069-1080.
35. - early precursor cells in the adult mouse thymus. Immunol. Lett. 40: 89-92.
36. Massa, S., G. Balciunaite, R. Ceredig, and A. G. Rolink. 2006. Critical role for c-kit (CD117) in T cell lineage commitment and early thymocyte development in vitro. Eur. J. Immunol. 36: 526-532.
37. Prockop, S. E., and H. T. Petrie. 2004. Regulation of thymus size by competition for stromal niches among early T cell progenitors. J. Immunol. 173: 1604-1611.
38. Dunon, D., N. Allioli, O. Vainio, C. Ody, and B. A. Imhof. 1999. Quantification of T-cell progenitors during ontogeny: thymus colonization depends on blood delivery of progenitors. Blood 93: 2234-2243.
39. Kuwata, N., H. Igarashi, T. Ohmura, S. Aizawa, and N. Sakaguchi. 1999. Cutting edge: Absence of expression of RAG 1 in peritoneal B-1 cells detected by knocking into RAG1 locus with green fluorescent protein gene. J. Immunol. 163: 6355-6359.
40. Taswell, C. 1984. Limiting dilution assays for the determination of immunocompetent cell frequencies. III. Validity tests for the single-hit Poisson model. J. Immunol. Methods 72: 29-40.
41. Spangrude, G. J., D. M. Brooks, and D. B. Tumas. 1995. Long-term repopulation of irradiated mice with limiting numbers of purified hematopoietic stem cells: in vivo expansion of stem cell phenotype but not function. Blood 85: 1006-1018.
42. Kawamoto, H., K. Ohmura, N. Hattori, and Y. Katsura. 1997. Hemopoietic progenitors in the murine fetal liver capable of rapidly generating T cells. J. Immunol. 158: 3118-3124.
43. +/- hematopoietic progenitor with potent lymphoid and myeloid developmental potential. Eur. J. Immunol. 35: 2019-2030.
44. Plotkin, J., S. E. Prockop, A. Lepique, and H. T. Petrie. 2003. Critical role for CXCR4 signaling in progenitor localization and T cell differentiation in the postnatal thymus. J. Immunol. 171: 4521-4527.
45. Traver, D., and K. Akashi. 2004. Lineage commitment and developmental plasticity in early lymphoid progenitor subsets. Adv. Immunol. 83: 1-54.
46. Miyamoto, T., H. Iwasaki, B. Reizis, M. Ye, T. Graf, I. L. Weissman, and K. Akashi. 2002. Myeloid or lymphoid promiscuity as a critical step in hematopoietic lineage commitment. Dev. Cell 3: 137-147.
47. Warren, L. A., and E. V. Rothenberg. 2003. Regulatory coding of lymphoid lineage choice by hematopoietic transcription factors. Curr. Opin. Immunol. 15: 166-175.
48. Baba, Y., R. Pelayo, and P. W. Kincade. 2004. Relationships between hematopoietic stem cells and lymphocyte progenitors. Trends Immunol. 25: 645-649.
49. Maillard, I., B. A. Schwarz, A. Sambandam, T. Fang, O. Shestova, L. Xu, A. Bhandoola, and W. S. Pear. 2006. Notch-dependent T-lineage commitment occurs at extrathymic sites following bone marrow transplantation. Blood 107: 3511-3519.
50. Lu, M., R. Tayu, T. Ikawa, K. Masuda, I. Matsumoto, H. Mugishima, H. Kawamoto, and Y. Katsura. 2005. The earliest thymic progenitors in adults are restricted to T, NK, and dendritic cell lineage and have a potential to form more diverse TCRβ chains than fetal progenitors. J. Immunol. 175: 5848-5856.
51. Kawamoto, H. 2006. A close developmental relationship between the lymphoid and myeloid lineages. Trends Immunol. epub ahead of print.
52. Ikawa, T., K. Masuda, M. Lu, N. Minato, Y. Katsura, and H. Kawamoto. 2004. Identification of the earliest prethymic T-cell progenitors in murine fetal blood. Blood 103: 530-537.
53. Harman, B. C., W. E. Jenkinson, S. M. Parnell, S. W. Rossi, E. J. Jenkinson, and G. Anderson. 2005. T/B lineage choice occurs prior to intrathymic Notch signaling. Blood 106: 886-892.
54. Godfrey, D. I., A. Zlotnik, and T. Suda. 1992. Phenotypic and functional characterization of c-kit expression during intrathymic T cell development. J. Immunol. 149: 2281-2285.
55. Moore, T. A., and A. Zlotnik. 1995. T-cell lineage commitment and cytokine responses of thymic progenitors. Blood 86: 1850-1860.
56. Wright, D. E., A. J. Wagers, A. P. Gulati, F. L. Johnson, and I. L. Weissman. 2001. Physiological migration of hematopoietic stem and progenitor cells. Science 294: 1933-1936.
57. Schwarz, B. A., and A. Bhandoola. 2004. Circulating hematopoietic progenitors with T lineage potential. Nat. Immunol. 5: 953-960.
58. - early B cell precursors. J. Exp. Med. 203: 675-687.