메뉴 건너뛰기




Volumn 19, Issue 7, 2008, Pages 655-671

Neurotransmission and cancer: Implications for prevention and therapy

Author keywords

Acetylcholine receptors; Autonomic nervous system; B adrenergic receptors; Cell type specific signaling; Regulation of cancer cell by neurotransmitters

Indexed keywords

4 AMINOBUTYRIC ACID; ACETYLCHOLINE; ADRENALIN; ALPHA ADRENERGIC RECEPTOR; ARACHIDONIC ACID; BETA ADRENERGIC RECEPTOR; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; GROWTH FACTOR; MUSCARINIC RECEPTOR; NEUROTRANSMITTER RECEPTOR; NICOTINE; NICOTINIC RECEPTOR; NITROSAMINE; NORADRENALIN; 4 AMINOBUTYRIC ACID RECEPTOR;

EID: 51049114513     PISSN: 09594973     EISSN: None     Source Type: Journal    
DOI: 10.1097/CAD.0b013e3283025b58     Document Type: Review
Times cited : (79)

References (165)
  • 2
    • 0033591845 scopus 로고    scopus 로고
    • Tobacco smoke carcinogens and lung cancer
    • Hecht SS. Tobacco smoke carcinogens and lung cancer. J Natl Cancer Inst 1999; 91:1194-1210.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 1194-1210
    • Hecht, S.S.1
  • 3
    • 38949170926 scopus 로고    scopus 로고
    • Progress and challenges in selected areas of tobacco carcinogenesis
    • Hecht SS. Progress and challenges in selected areas of tobacco carcinogenesis. Chem Res Toxicol 2008; 21:160-171.
    • (2008) Chem Res Toxicol , vol.21 , pp. 160-171
    • Hecht, S.S.1
  • 4
    • 0029837050 scopus 로고    scopus 로고
    • Chemoprevention of lung cancer by isothiocyanates
    • Hecht SS. Chemoprevention of lung cancer by isothiocyanates. Adv Exp Med Biol 1996; 401:1-11.
    • (1996) Adv Exp Med Biol , vol.401 , pp. 1-11
    • Hecht, S.S.1
  • 5
    • 38349000628 scopus 로고    scopus 로고
    • Cancer chemoprevention through dietary antioxidants: Progress and promise
    • Khan N, Afaq F, Mukhtar H. Cancer chemoprevention through dietary antioxidants: progress and promise. Antioxid Redox Signal 2007; 10: 475-510.
    • (2007) Antioxid Redox Signal , vol.10 , pp. 475-510
    • Khan, N.1    Afaq, F.2    Mukhtar, H.3
  • 6
    • 0032997929 scopus 로고    scopus 로고
    • The prevention of lung cancer induced by a tobacco-specific carcinogen in rodents by green and black tea
    • Chung FL. The prevention of lung cancer induced by a tobacco-specific carcinogen in rodents by green and black tea. Proc Soc Exp Biol Med 1999; 220:244-248.
    • (1999) Proc Soc Exp Biol Med , vol.220 , pp. 244-248
    • Chung, F.L.1
  • 7
    • 0036637235 scopus 로고    scopus 로고
    • Chemoprevention: An essential approach to controlling cancer
    • Sporn MB, Suh N. Chemoprevention: an essential approach to controlling cancer. Nat Rev Cancer 2002; 2:537-543.
    • (2002) Nat Rev Cancer , vol.2 , pp. 537-543
    • Sporn, M.B.1    Suh, N.2
  • 8
    • 40049094394 scopus 로고    scopus 로고
    • Combined chemoradiotherapy advances
    • Wong G, Metha MP. Combined chemoradiotherapy advances. Cancer Treat Res 2008; 139:281-305.
    • (2008) Cancer Treat Res , vol.139 , pp. 281-305
    • Wong, G.1    Metha, M.P.2
  • 9
    • 25644461068 scopus 로고    scopus 로고
    • International lung cancer trends by histologic type: Male:female differences diminishing and adenocarcinoma rates rising
    • Devesa SS, Bray F, Vizcaino AP, Parkin DM. International lung cancer trends by histologic type: male:female differences diminishing and adenocarcinoma rates rising. Int J Cancer 2005; 117:294-299.
    • (2005) Int J Cancer , vol.117 , pp. 294-299
    • Devesa, S.S.1    Bray, F.2    Vizcaino, A.P.3    Parkin, D.M.4
  • 10
    • 18044385371 scopus 로고    scopus 로고
    • Steroid hormone receptors as targets for the therapy of breast and prostate cancer-recent advances, mechanisms of resistance, and new approaches
    • Hoffmann J, Sommer A. Steroid hormone receptors as targets for the therapy of breast and prostate cancer-recent advances, mechanisms of resistance, and new approaches. J Steroid Biochem Mol Biol 2005; 93:191-200.
    • (2005) J Steroid Biochem Mol Biol , vol.93 , pp. 191-200
    • Hoffmann, J.1    Sommer, A.2
  • 11
    • 0025616930 scopus 로고
    • The beta-adrenergic system in man: Physiological and pathophysiological response. Regulation of receptor density and functioning
    • Maki T, Kontula K, Harkonen M. The beta-adrenergic system in man: physiological and pathophysiological response. Regulation of receptor density and functioning. Scand J Clin Lab Invest Suppl 1990; 201:25-43.
    • (1990) Scand J Clin Lab Invest Suppl , vol.201 , pp. 25-43
    • Maki, T.1    Kontula, K.2    Harkonen, M.3
  • 12
    • 0024417622 scopus 로고
    • Cell type specific, receptor-mediated modulation of growth kinetics in human lung cancer cell lines by nicotine and tobacco-related nitrosamines
    • Schuller HM. Cell type specific, receptor-mediated modulation of growth kinetics in human lung cancer cell lines by nicotine and tobacco-related nitrosamines. Biochem Pharmacol 1989; 38:3439-3442.
    • (1989) Biochem Pharmacol , vol.38 , pp. 3439-3442
    • Schuller, H.M.1
  • 13
    • 0024470434 scopus 로고
    • Regulation of cell proliferation by beta-adrenergic receptors in a human lung adenocarcinoma cell line
    • Schuller HM, Cole B. Regulation of cell proliferation by beta-adrenergic receptors in a human lung adenocarcinoma cell line. Carcinogenesis 1989; 10:1753-1755.
    • (1989) Carcinogenesis , vol.10 , pp. 1753-1755
    • Schuller, H.M.1    Cole, B.2
  • 14
    • 0036597698 scopus 로고    scopus 로고
    • Mechanisms of smoking-related lung and pancreatic adenocarcinoma development
    • Schuller HM. Mechanisms of smoking-related lung and pancreatic adenocarcinoma development. Nat Rev Cancer 2002; 2:455-463.
    • (2002) Nat Rev Cancer , vol.2 , pp. 455-463
    • Schuller, H.M.1
  • 15
    • 33847381505 scopus 로고    scopus 로고
    • Neurotransmitter receptor-mediated signaling pathways as modulators of carcinogenesis
    • Zänker KS, Enschladen F, editors, Basel: Karger;
    • Schuller HM. Neurotransmitter receptor-mediated signaling pathways as modulators of carcinogenesis. In: Zänker KS, Enschladen F, editors. Neuronal activity in tumor tissue. Basel: Karger; 2007. pp. 45-63.
    • (2007) Neuronal activity in tumor tissue , pp. 45-63
    • Schuller, H.M.1
  • 16
    • 23044512910 scopus 로고    scopus 로고
    • The brain within the tumor: New role for axon guidance molecules in cancers
    • Cheodotal A, Kerjan G, Moreau-Fauvarque C. The brain within the tumor: new role for axon guidance molecules in cancers. Cell Death Differ 2005; 12:1044-1056.
    • (2005) Cell Death Differ , vol.12 , pp. 1044-1056
    • Cheodotal, A.1    Kerjan, G.2    Moreau-Fauvarque, C.3
  • 17
    • 33847380198 scopus 로고    scopus 로고
    • Neoneurogenesis and the neuro-neoplastic synapse
    • Zänker KS, Entschladen F, editors, Basel: Karger;
    • Palm D, Entschladen F. Neoneurogenesis and the neuro-neoplastic synapse. In: Zänker KS, Entschladen F, editors. Neuronal activity in tumor tissue. Basel: Karger; 2007. pp. 91-98.
    • (2007) Neuronal activity in tumor tissue , pp. 91-98
    • Palm, D.1    Entschladen, F.2
  • 19
    • 0031964633 scopus 로고    scopus 로고
    • Non-neuronal acetylcholine, a locally acting molecule, widely distributed in biological systems: Expression and function in humans
    • Wessler I, Kirkpatrick CJ, Racke K. Non-neuronal acetylcholine, a locally acting molecule, widely distributed in biological systems: expression and function in humans. Pharmacol Ther 1998; 77:59-79.
    • (1998) Pharmacol Ther , vol.77 , pp. 59-79
    • Wessler, I.1    Kirkpatrick, C.J.2    Racke, K.3
  • 20
    • 0042067949 scopus 로고    scopus 로고
    • Assembly and subunit diversity of nicotinic acetylcholine receptors
    • Millar NS. Assembly and subunit diversity of nicotinic acetylcholine receptors. Biochem Soc Trans 2003; 31:869-874.
    • (2003) Biochem Soc Trans , vol.31 , pp. 869-874
    • Millar, N.S.1
  • 21
    • 1842366036 scopus 로고    scopus 로고
    • Differential regulation of neuronal nicotinic receptor binding sites following chronic nicotine administration
    • Flores CM, Davila-Garcia MI, Ulrich YM, Kellar KJ. Differential regulation of neuronal nicotinic receptor binding sites following chronic nicotine administration. J Neurochem 1997; 69:2216-2219.
    • (1997) J Neurochem , vol.69 , pp. 2216-2219
    • Flores, C.M.1    Davila-Garcia, M.I.2    Ulrich, Y.M.3    Kellar, K.J.4
  • 22
    • 20444368757 scopus 로고    scopus 로고
    • Chronic nicotine exposure upregulates nicotinic receptors by a novel mechanism
    • Vallejo YF, Buisson B, Bertrand D, Green WN. Chronic nicotine exposure upregulates nicotinic receptors by a novel mechanism. J Neurosci 2005; 25:5563-5572.
    • (2005) J Neurosci , vol.25 , pp. 5563-5572
    • Vallejo, Y.F.1    Buisson, B.2    Bertrand, D.3    Green, W.N.4
  • 23
    • 0035930960 scopus 로고    scopus 로고
    • Expression of nicotinic acetylcholine receptors in human and rat adrenal medulla
    • Mousavi M, Hellstrom-Lindahl E, Guan ZZ, Bednar I, Nordberg A. Expression of nicotinic acetylcholine receptors in human and rat adrenal medulla. Life Sci 2001; 70:577-590.
    • (2001) Life Sci , vol.70 , pp. 577-590
    • Mousavi, M.1    Hellstrom-Lindahl, E.2    Guan, Z.Z.3    Bednar, I.4    Nordberg, A.5
  • 24
    • 0024576705 scopus 로고
    • Effects of endogeneous and tobacco-related amines and nitrosamines on cell growth and morphology of a cell line derived from a human neuroendocrine lung cancer
    • Schuller HM, Hegedus TJ. Effects of endogeneous and tobacco-related amines and nitrosamines on cell growth and morphology of a cell line derived from a human neuroendocrine lung cancer. Toxicol In Vitro 1989; 3:37-43.
    • (1989) Toxicol In Vitro , vol.3 , pp. 37-43
    • Schuller, H.M.1    Hegedus, T.J.2
  • 25
    • 0025341202 scopus 로고
    • Opioid and nicotine receptors affect growth regulation of human lung cancer cell lines
    • Maneckjee R, Minna JD. Opioid and nicotine receptors affect growth regulation of human lung cancer cell lines. Proc Natl Acad Sci U S A 1989; 87:3294-3298.
    • (1989) Proc Natl Acad Sci U S A , vol.87 , pp. 3294-3298
    • Maneckjee, R.1    Minna, J.D.2
  • 26
    • 0027985282 scopus 로고
    • Opioids induce while nicotine suppresses apoptosis in human lung cancer cells
    • Maneckjee R, Minna JD. Opioids induce while nicotine suppresses apoptosis in human lung cancer cells. Cell Growth Differ 1994; 5: 1033-1040.
    • (1994) Cell Growth Differ , vol.5 , pp. 1033-1040
    • Maneckjee, R.1    Minna, J.D.2
  • 27
    • 0027442825 scopus 로고
    • Nicotine stimulates a serotonergic autocrine loop in human small-cell lung carcinoma
    • Cattaneo MG, Codignola A, Vicentini LM, Clementi F, Sher E. Nicotine stimulates a serotonergic autocrine loop in human small-cell lung carcinoma. Cancer Res 1993; 53:5566-5568.
    • (1993) Cancer Res , vol.53 , pp. 5566-5568
    • Cattaneo, M.G.1    Codignola, A.2    Vicentini, L.M.3    Clementi, F.4    Sher, E.5
  • 28
    • 0032499397 scopus 로고    scopus 로고
    • Tobacco-specific carcinogenic nitrosamines. Ligands for nicotinic acetylcholine receptors in human lung cancer cells
    • Schuller HM, Orloff M. Tobacco-specific carcinogenic nitrosamines. Ligands for nicotinic acetylcholine receptors in human lung cancer cells. Biochem Pharmacol 1998; 55:1377-1384.
    • (1998) Biochem Pharmacol , vol.55 , pp. 1377-1384
    • Schuller, H.M.1    Orloff, M.2
  • 29
    • 24344492234 scopus 로고    scopus 로고
    • Expression of the alpha7 nicotinic acetylcholine receptor in human lung cells
    • Plummer HK III, Dhar M, Schuller HM. Expression of the alpha7 nicotinic acetylcholine receptor in human lung cells. Respir Res 2005; 6:29.
    • (2005) Respir Res , vol.6 , pp. 29
    • Plummer III, H.K.1    Dhar, M.2    Schuller, H.M.3
  • 30
    • 33646800564 scopus 로고    scopus 로고
    • Nicotinic receptors mediate tumorigenic action of tobacco-derived nitrosamines on immortalized oral epithelial cells
    • Arredondo J, Chernyavsky AI, Grando SA. Nicotinic receptors mediate tumorigenic action of tobacco-derived nitrosamines on immortalized oral epithelial cells. Cancer Biol Ther 2006; 5:511-517.
    • (2006) Cancer Biol Ther , vol.5 , pp. 511-517
    • Arredondo, J.1    Chernyavsky, A.I.2    Grando, S.A.3
  • 32
    • 0034146188 scopus 로고    scopus 로고
    • Activation of voltage-operated Ca2 + -channels in human small cell lung carcinoma by the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone
    • Sheppard BJ, Williams M, Plummer HK, Schuller HM. Activation of voltage-operated Ca2 + -channels in human small cell lung carcinoma by the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Int J Oncol 2000; 16:513-518.
    • (2000) Int J Oncol , vol.16 , pp. 513-518
    • Sheppard, B.J.1    Williams, M.2    Plummer, H.K.3    Schuller, H.M.4
  • 33
    • 0034732219 scopus 로고    scopus 로고
    • Interaction of tobacco-specific toxicants with the neuronal alpha(7) nicotinic acetylcholine receptor and its associated mitogenic signal transduction pathway: Potential role in lung carcinogenesis and pediatric lung disorders
    • Schuller HM, Jull BA, Sheppard BJ, Plummer HK. Interaction of tobacco-specific toxicants with the neuronal alpha(7) nicotinic acetylcholine receptor and its associated mitogenic signal transduction pathway: potential role in lung carcinogenesis and pediatric lung disorders. Eur J Pharmacol 2000; 393:265-277.
    • (2000) Eur J Pharmacol , vol.393 , pp. 265-277
    • Schuller, H.M.1    Jull, B.A.2    Sheppard, B.J.3    Plummer, H.K.4
  • 34
    • 4544305469 scopus 로고    scopus 로고
    • Tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone promotes functional cooperation of Bcl2 and c-Myc through phosphorylation in regulating cell survival and proliferation
    • Jin Z, Gao F, Flagg T, Deng X. Tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone promotes functional cooperation of Bcl2 and c-Myc through phosphorylation in regulating cell survival and proliferation. J Biol Chem 2004; 279:40209-40219.
    • (2004) J Biol Chem , vol.279 , pp. 40209-40219
    • Jin, Z.1    Gao, F.2    Flagg, T.3    Deng, X.4
  • 35
    • 11144227597 scopus 로고    scopus 로고
    • Tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3- pyridyl)-1-butanone induces phosphorylation of mu- and m-calpain in association with increased secretion, cell migration, and invasion
    • Xu L, Deng X. Tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3- pyridyl)-1-butanone induces phosphorylation of mu- and m-calpain in association with increased secretion, cell migration, and invasion. J Biol Chem 2004; 279:53683-53690.
    • (2004) J Biol Chem , vol.279 , pp. 53683-53690
    • Xu, L.1    Deng, X.2
  • 36
    • 0028207396 scopus 로고
    • Serotonin release and cell proliferation are under the control of alpha-bungarotoxin-sensitive nicotinic receptors in small-cell lung carcinoma cell lines
    • Codignola A, Tarroni P, Cattaneo MG, Vicentini LM, Clementi F, Sher E. Serotonin release and cell proliferation are under the control of alpha-bungarotoxin-sensitive nicotinic receptors in small-cell lung carcinoma cell lines. FEBS Lett 1994; 342:286-290.
    • (1994) FEBS Lett , vol.342 , pp. 286-290
    • Codignola, A.1    Tarroni, P.2    Cattaneo, M.G.3    Vicentini, L.M.4    Clementi, F.5    Sher, E.6
  • 37
    • 0034738958 scopus 로고    scopus 로고
    • The galanin receptor type 2 initiates multiple signaling pathways in small cell lung cancer cells by coupling to G(q), G(i) and G(12) proteins
    • Wittau N, Grosse R, Kalkbrenner F, Gohla A, Schultz G, Gudermann T. The galanin receptor type 2 initiates multiple signaling pathways in small cell lung cancer cells by coupling to G(q), G(i) and G(12) proteins. Oncogene 2000; 19:4199-4209.
    • (2000) Oncogene , vol.19 , pp. 4199-4209
    • Wittau, N.1    Grosse, R.2    Kalkbrenner, F.3    Gohla, A.4    Schultz, G.5    Gudermann, T.6
  • 38
    • 0029730774 scopus 로고    scopus 로고
    • Galanin, neurotensin, and phorbol esters rapidly stimulate activation of mitogen-activated protein kinase in small cell lung cancer cells
    • Seufferlein T, Rozengurt E. Galanin, neurotensin, and phorbol esters rapidly stimulate activation of mitogen-activated protein kinase in small cell lung cancer cells. Cancer Res 1996; 56:5758-5764.
    • (1996) Cancer Res , vol.56 , pp. 5758-5764
    • Seufferlein, T.1    Rozengurt, E.2
  • 39
    • 0025267835 scopus 로고
    • Pathobiology of lung tumors induced in hamsters by 4-(methylnitrosamino)-1-(3- pyridyl)-1-butanone and the modulating effect of hyperoxia
    • Schuller HM, Witschi HP, Nylen E, Joshi PA, Correa E, Becker KL. Pathobiology of lung tumors induced in hamsters by 4-(methylnitrosamino)-1-(3- pyridyl)-1-butanone and the modulating effect of hyperoxia. Cancer Res 1990; 50:1960-1965.
    • (1990) Cancer Res , vol.50 , pp. 1960-1965
    • Schuller, H.M.1    Witschi, H.P.2    Nylen, E.3    Joshi, P.A.4    Correa, E.5    Becker, K.L.6
  • 40
    • 0022063934 scopus 로고
    • Neuroendocrine cells in the developing human lung: Morphologic and functional considerations
    • Cutz E, Gillan JE, Bryan AC. Neuroendocrine cells in the developing human lung: morphologic and functional considerations. Pediatr Pulmonol 1985; 1:S21-S29.
    • (1985) Pediatr Pulmonol , vol.1
    • Cutz, E.1    Gillan, J.E.2    Bryan, A.C.3
  • 41
    • 0031115257 scopus 로고    scopus 로고
    • Introduction to pulmonary neuroendocrine cell system, structure-function correlations
    • Cutz E. Introduction to pulmonary neuroendocrine cell system, structure-function correlations. Microsc Res Tech 1997; 37:1-3.
    • (1997) Microsc Res Tech , vol.37 , pp. 1-3
    • Cutz, E.1
  • 42
    • 0033004626 scopus 로고    scopus 로고
    • Neuroepithelial bodies as airway oxygen sensors
    • Cutz E, Jackson A. Neuroepithelial bodies as airway oxygen sensors. Respir Physiol 1999; 115:201-214.
    • (1999) Respir Physiol , vol.115 , pp. 201-214
    • Cutz, E.1    Jackson, A.2
  • 43
    • 0027948449 scopus 로고
    • Characterization of membrane currents in pulmonary neuroepithelial bodies: Hypoxia-sensitive airway chemoreceptors
    • Youngson C, Nurse C, Yeger H, Cutz E. Characterization of membrane currents in pulmonary neuroepithelial bodies: hypoxia-sensitive airway chemoreceptors. Adv Exp Med Biol 1994; 360:179-182.
    • (1994) Adv Exp Med Biol , vol.360 , pp. 179-182
    • Youngson, C.1    Nurse, C.2    Yeger, H.3    Cutz, E.4
  • 44
    • 0027327956 scopus 로고
    • Oxygen sensing in airway chemoreceptors
    • Youngson C, Nurse C, Yeger H, Cutz E. Oxygen sensing in airway chemoreceptors. Nature 1993; 365:153-155.
    • (1993) Nature , vol.365 , pp. 153-155
    • Youngson, C.1    Nurse, C.2    Yeger, H.3    Cutz, E.4
  • 45
    • 33846215065 scopus 로고    scopus 로고
    • Impaired lung function and lung cancer incidence in a cohort of Swedish construction workers
    • Purdue MP, Gold L, Jarvholm B, Alavanja MC, Ward MH, Vermeulen R. Impaired lung function and lung cancer incidence in a cohort of Swedish construction workers. Thorax 2007; 62:51-56.
    • (2007) Thorax , vol.62 , pp. 51-56
    • Purdue, M.P.1    Gold, L.2    Jarvholm, B.3    Alavanja, M.C.4    Ward, M.H.5    Vermeulen, R.6
  • 46
    • 34249284421 scopus 로고    scopus 로고
    • Nitrosamines as nicotinic receptor ligands
    • Schuller HM. Nitrosamines as nicotinic receptor ligands. Life Sci 2007; 80:2274-2280.
    • (2007) Life Sci , vol.80 , pp. 2274-2280
    • Schuller, H.M.1
  • 48
    • 0028123406 scopus 로고
    • Molecular characterization of neuroendocrine lung tumors induced in hamsters by treatment with nitrosamine and hyperoxia
    • Miller MS, Baxter JL, Moore JD, Schuller HM. Molecular characterization of neuroendocrine lung tumors induced in hamsters by treatment with nitrosamine and hyperoxia. Int J Oncol 1994; 4:5-12.
    • (1994) Int J Oncol , vol.4 , pp. 5-12
    • Miller, M.S.1    Baxter, J.L.2    Moore, J.D.3    Schuller, H.M.4
  • 49
    • 0029116817 scopus 로고
    • Simultaneous exposure to nicotine and hyperoxia causes tumors in hamsters
    • Schuller HM, McGavin MD, Orloff M, Riechert A, Porter B. Simultaneous exposure to nicotine and hyperoxia causes tumors in hamsters. Lab Invest 1995; 73:448-456.
    • (1995) Lab Invest , vol.73 , pp. 448-456
    • Schuller, H.M.1    McGavin, M.D.2    Orloff, M.3    Riechert, A.4    Porter, B.5
  • 50
    • 0030814607 scopus 로고    scopus 로고
    • Carbon dioxide, an important messenger molecule for small cell lung cancer
    • Merryman JI, Park PG, Schuller HM. Carbon dioxide, an important messenger molecule for small cell lung cancer. Chest 1997; 112: 779-784.
    • (1997) Chest , vol.112 , pp. 779-784
    • Merryman, J.I.1    Park, P.G.2    Schuller, H.M.3
  • 51
    • 0028588676 scopus 로고
    • Carbon dioxide potentiates the mitogenic effects of nicotine and its carcinogenic derivative, NNK, in normal and neoplastic neuroendocrine lung cells via stimulation of autocrine and protein kinase C-dependent mitogenic pathways
    • Schuller HM. Carbon dioxide potentiates the mitogenic effects of nicotine and its carcinogenic derivative, NNK, in normal and neoplastic neuroendocrine lung cells via stimulation of autocrine and protein kinase C-dependent mitogenic pathways. Neurotoxicology 1994; 15:877-886.
    • (1994) Neurotoxicology , vol.15 , pp. 877-886
    • Schuller, H.M.1
  • 52
    • 0029664496 scopus 로고    scopus 로고
    • Promoting mechanisms of CO2 on neuroendocrine cell proliferation mediated by nicotinic receptor stimulation. Significance for lung cancer risk in individuals with chronic lung disease
    • Schuller HM, Miller MS, Park PG, Orloff MS. Promoting mechanisms of CO2 on neuroendocrine cell proliferation mediated by nicotinic receptor stimulation. Significance for lung cancer risk in individuals with chronic lung disease. Chest 1996; 109:20S-21S.
    • (1996) Chest , vol.109
    • Schuller, H.M.1    Miller, M.S.2    Park, P.G.3    Orloff, M.S.4
  • 54
    • 0344958586 scopus 로고    scopus 로고
    • Prenatal nicotine increases pulmonary alpha7 nicotinic receptor expression and alters fetal lung development in monkeys
    • Sekhon HS, Jia Y, Raab R, Kuryatov A, Pankow JF, Whitsett JA, et al. Prenatal nicotine increases pulmonary alpha7 nicotinic receptor expression and alters fetal lung development in monkeys. J Clin Invest 1999; 103:637-647.
    • (1999) J Clin Invest , vol.103 , pp. 637-647
    • Sekhon, H.S.1    Jia, Y.2    Raab, R.3    Kuryatov, A.4    Pankow, J.F.5    Whitsett, J.A.6
  • 55
    • 0141885402 scopus 로고    scopus 로고
    • Receptor-mediated effects of nicotine and its nitrosated derivative NNK on pulmonary neuroendocrine cells
    • Schuller HM, Plummer HK III, Jull BA. Receptor-mediated effects of nicotine and its nitrosated derivative NNK on pulmonary neuroendocrine cells. Anat Rec 2003; 270:51-58.
    • (2003) Anat Rec , vol.270 , pp. 51-58
    • Schuller, H.M.1    Plummer III, H.K.2    Jull, B.A.3
  • 56
    • 0016711397 scopus 로고
    • Transplacental effects of diethylnitrosamine in Syrian hamsters as related to different days of administration during pregnancy
    • Mohr U, Reznik-Schuller H, Reznik G, Hilfrich J. Transplacental effects of diethylnitrosamine in Syrian hamsters as related to different days of administration during pregnancy. J Natl Cancer Inst 1975; 55:681-683.
    • (1975) J Natl Cancer Inst , vol.55 , pp. 681-683
    • Mohr, U.1    Reznik-Schuller, H.2    Reznik, G.3    Hilfrich, J.4
  • 57
    • 0025311241 scopus 로고
    • The tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone is an active transplacental carcinogen in Syrian golden hamsters
    • Correa E, Joshi PA, Castonguay A, Schuller HM. The tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone is an active transplacental carcinogen in Syrian golden hamsters. Cancer Res 1990; 50:3435-3438.
    • (1990) Cancer Res , vol.50 , pp. 3435-3438
    • Correa, E.1    Joshi, P.A.2    Castonguay, A.3    Schuller, H.M.4
  • 58
    • 0344064935 scopus 로고    scopus 로고
    • Neuronal nicotinic acetylcholine receptors: Not just in brain
    • Spindel ER. Neuronal nicotinic acetylcholine receptors: not just in brain. Am J Physiol Lung Cell Mol Physiol 2003; 285:L1201-L1202.
    • (2003) Am J Physiol Lung Cell Mol Physiol , vol.285
    • Spindel, E.R.1
  • 59
    • 34250307900 scopus 로고    scopus 로고
    • Expression of nicotinic acetylcholine receptor subunit genes in non-small-cell lung cancer reveals differences between smokers and nonsmokers
    • Lam DC, Girard L, Ramirez R, Chau WS, Suen WS, Sheridan S, et al. Expression of nicotinic acetylcholine receptor subunit genes in non-small-cell lung cancer reveals differences between smokers and nonsmokers. Cancer Res 2007; 67:4638-4647.
    • (2007) Cancer Res , vol.67 , pp. 4638-4647
    • Lam, D.C.1    Girard, L.2    Ramirez, R.3    Chau, W.S.4    Suen, W.S.5    Sheridan, S.6
  • 60
    • 0037251810 scopus 로고    scopus 로고
    • Rapid AKT activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells
    • West KA, Brognard J, Clark AS, Linnoila IR, Yang X, Swain SM, et al. Rapid AKT activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells. J Clin Invest 2003; 111:81-90.
    • (2003) J Clin Invest , vol.111 , pp. 81-90
    • West, K.A.1    Brognard, J.2    Clark, A.S.3    Linnoila, I.R.4    Yang, X.5    Swain, S.M.6
  • 61
    • 21044454180 scopus 로고    scopus 로고
    • Tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces cell proliferation in normal human bronchial epithelial cells through NFkappaB activation and cyclin D1 up-regulation
    • Ho YS, Chen CH, Wang YJ, Pestell RG, Albanese C, Chen RJ, et al. Tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces cell proliferation in normal human bronchial epithelial cells through NFkappaB activation and cyclin D1 up-regulation. Toxicol Appl Pharmacol 2005; 205:133-148.
    • (2005) Toxicol Appl Pharmacol , vol.205 , pp. 133-148
    • Ho, Y.S.1    Chen, C.H.2    Wang, Y.J.3    Pestell, R.G.4    Albanese, C.5    Chen, R.J.6
  • 62
    • 36749016741 scopus 로고    scopus 로고
    • Nicotine stimulates human lung cancer cell growth by inducing fibronectin expression
    • Zheng Y, Ritzenthaler JD, Roman J, Han S. Nicotine stimulates human lung cancer cell growth by inducing fibronectin expression. Am J Respir Cell Mol Biol 2007; 37:681-690.
    • (2007) Am J Respir Cell Mol Biol , vol.37 , pp. 681-690
    • Zheng, Y.1    Ritzenthaler, J.D.2    Roman, J.3    Han, S.4
  • 63
    • 33746672599 scopus 로고    scopus 로고
    • Nicotine induces cell proliferation by beta-arrestin-mediated activation of Src and Rb-Raf-1 pathways
    • Dasgupta P, Rastogi S, Pillai S, Ordonez-Ercan D, Morris M, Haura E, et al. Nicotine induces cell proliferation by beta-arrestin-mediated activation of Src and Rb-Raf-1 pathways. J Clin Invest 2006; 116:2208-2217.
    • (2006) J Clin Invest , vol.116 , pp. 2208-2217
    • Dasgupta, P.1    Rastogi, S.2    Pillai, S.3    Ordonez-Ercan, D.4    Morris, M.5    Haura, E.6
  • 64
    • 33646598093 scopus 로고    scopus 로고
    • Nicotine inhibits apoptosis induced by chemotherapeutic drugs by up-regulating XIAP and survivin
    • Dasgupta P, Kinkade R, Joshi B, Decook C, Haura E, Chellappan S. Nicotine inhibits apoptosis induced by chemotherapeutic drugs by up-regulating XIAP and survivin. Proc Natl Acad Sci U S A 2006; 103: 6332-6337.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 6332-6337
    • Dasgupta, P.1    Kinkade, R.2    Joshi, B.3    Decook, C.4    Haura, E.5    Chellappan, S.6
  • 67
    • 1642568706 scopus 로고    scopus 로고
    • Alpha7-nicotinic acetylcholine receptors affect growth regulation of human mesothelioma cells: Role of mitogen-activated protein kinase pathway
    • Trombino S, Cesario A, Margaritora S, Granone P, Motta G, Falugi C, et al. Alpha7-nicotinic acetylcholine receptors affect growth regulation of human mesothelioma cells: role of mitogen-activated protein kinase pathway. Cancer Res 2004; 64:135-145.
    • (2004) Cancer Res , vol.64 , pp. 135-145
    • Trombino, S.1    Cesario, A.2    Margaritora, S.3    Granone, P.4    Motta, G.5    Falugi, C.6
  • 68
    • 34249776345 scopus 로고    scopus 로고
    • Nicotine promotes cell proliferation via alpha7-nicotinic acetylcholine receptor and catecholamine-synthesizing enzymes-mediated pathway in human colon adenocarcinoma HT-29 cells
    • Wong HP, Yu L, Lam EK, Tai EK, Wu WK, Cho CH. Nicotine promotes cell proliferation via alpha7-nicotinic acetylcholine receptor and catecholamine-synthesizing enzymes-mediated pathway in human colon adenocarcinoma HT-29 cells. Toxicol Appl Pharmacol 2007; 221:261-267.
    • (2007) Toxicol Appl Pharmacol , vol.221 , pp. 261-267
    • Wong, H.P.1    Yu, L.2    Lam, E.K.3    Tai, E.K.4    Wu, W.K.5    Cho, C.H.6
  • 69
    • 33847316161 scopus 로고    scopus 로고
    • Functional role of beta-adrenergic receptors in the mitogenic action of nicotine on gastric cancer cells
    • Shin VY, Wu WK, Chu KM, Koo MW, Wong HP, Lam EK, et al. Functional role of beta-adrenergic receptors in the mitogenic action of nicotine on gastric cancer cells. Toxicol Sci 2007; 96:21-29.
    • (2007) Toxicol Sci , vol.96 , pp. 21-29
    • Shin, V.Y.1    Wu, W.K.2    Chu, K.M.3    Koo, M.W.4    Wong, H.P.5    Lam, E.K.6
  • 70
    • 10344240356 scopus 로고    scopus 로고
    • Nicotine promotes gastric tumor growth and neovascularization by activating extracellular signal-regulated kinase and cyclooxygenase-2
    • Shin VY, Wu WK,Ye YN, So WH, Koo MW, Liu ES, et al. Nicotine promotes gastric tumor growth and neovascularization by activating extracellular signal-regulated kinase and cyclooxygenase-2. Carcinogenesis 2004; 25:2487-2495.
    • (2004) Carcinogenesis , vol.25 , pp. 2487-2495
    • Shin, V.Y.1    Wu, W.K.2    Ye, Y.N.3    So, W.H.4    Koo, M.W.5    Liu, E.S.6
  • 71
    • 0033568544 scopus 로고    scopus 로고
    • The tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone is a beta-adrenergic agonist and stimulates DNA synthesis in lung adenocarcinoma via beta-adrenergic receptor-mediated release of arachidonic acid
    • Schuller HM, Tithof PK, Williams M, Plummer H III. The tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone is a beta-adrenergic agonist and stimulates DNA synthesis in lung adenocarcinoma via beta-adrenergic receptor-mediated release of arachidonic acid. Cancer Res 1999; 59:4510-4515.
    • (1999) Cancer Res , vol.59 , pp. 4510-4515
    • Schuller, H.M.1    Tithof, P.K.2    Williams, M.3    Plummer III, H.4
  • 72
    • 0035203756 scopus 로고    scopus 로고
    • Tithof PK, Elgayyar M, Schuller HM, Barnhill M, Andrews R. 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a nicotine derivative, induces apoptosis of endothelial cells. Am J Physiol Heart Circ Physiol 2001; 281:H1946-H1954.
    • Tithof PK, Elgayyar M, Schuller HM, Barnhill M, Andrews R. 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a nicotine derivative, induces apoptosis of endothelial cells. Am J Physiol Heart Circ Physiol 2001; 281:H1946-H1954.
  • 73
    • 33751261895 scopus 로고    scopus 로고
    • Norepinephrine up-regulates the expression of vascular endothelial growth factor, matrix metalloproteinase (MMP)-2, and MMP-9 in nasopharyngeal carcinoma tumor cells
    • Yang EV, Sood AK, Chen M, Li Y, Eubank TD, Marsh CB, et al. Norepinephrine up-regulates the expression of vascular endothelial growth factor, matrix metalloproteinase (MMP)-2, and MMP-9 in nasopharyngeal carcinoma tumor cells. Cancer Res 2006; 66:10357-10364.
    • (2006) Cancer Res , vol.66 , pp. 10357-10364
    • Yang, E.V.1    Sood, A.K.2    Chen, M.3    Li, Y.4    Eubank, T.D.5    Marsh, C.B.6
  • 74
    • 28444483272 scopus 로고    scopus 로고
    • Beta-adrenergic receptor agonists induce the release of granulocyte chemotactic protein-2, oncostatin M, and vascular endothelial growth factor from macrophages
    • Verhoeckx KC, Doornbos RP, Witkamp RF, van der Greef J, Rodenburg RJ. Beta-adrenergic receptor agonists induce the release of granulocyte chemotactic protein-2, oncostatin M, and vascular endothelial growth factor from macrophages. Int Immunopharmacol 2006; 6:1-7.
    • (2006) Int Immunopharmacol , vol.6 , pp. 1-7
    • Verhoeckx, K.C.1    Doornbos, R.P.2    Witkamp, R.F.3    van der Greef, J.4    Rodenburg, R.J.5
  • 75
    • 34247100272 scopus 로고    scopus 로고
    • Epithelial cell nicotinic acetylcholine receptor expression in head and neck squamous cell carcinoma pathogenesis
    • Carracedo DG, Rodrigo JP, Nieto CS, Gonzalez MV. Epithelial cell nicotinic acetylcholine receptor expression in head and neck squamous cell carcinoma pathogenesis. Anticancer Res 2007; 27:835-839.
    • (2007) Anticancer Res , vol.27 , pp. 835-839
    • Carracedo, D.G.1    Rodrigo, J.P.2    Nieto, C.S.3    Gonzalez, M.V.4
  • 76
    • 33750135226 scopus 로고    scopus 로고
    • Receptor-mediated tobacco toxicity: Cooperation of the Ras/Raf-1/MEK1/ ERK and JAK-2/STAT-3 pathways downstream of alpha7 nicotinic receptor in oral keratinocytes
    • Arredondo J, Chernyavsky AI, Jolkovsky DL, Pinkerton KE, Grando SA. Receptor-mediated tobacco toxicity: cooperation of the Ras/Raf-1/MEK1/ ERK and JAK-2/STAT-3 pathways downstream of alpha7 nicotinic receptor in oral keratinocytes. FASEB J 2006; 20:2093-2101.
    • (2006) FASEB J , vol.20 , pp. 2093-2101
    • Arredondo, J.1    Chernyavsky, A.I.2    Jolkovsky, D.L.3    Pinkerton, K.E.4    Grando, S.A.5
  • 77
    • 34249704581 scopus 로고    scopus 로고
    • Receptor-mediated tobacco toxicity: Alterations of the NF-kappaB expression and activity downstream of alpha7 nicotinic receptor in oral keratinocytes
    • Arredondo J, Chernyavsky AI, Jolkovsky DL, Pinkerton KE, Grando SA. Receptor-mediated tobacco toxicity: alterations of the NF-kappaB expression and activity downstream of alpha7 nicotinic receptor in oral keratinocytes. Life Sci 2007; 80:2191-2194.
    • (2007) Life Sci , vol.80 , pp. 2191-2194
    • Arredondo, J.1    Chernyavsky, A.I.2    Jolkovsky, D.L.3    Pinkerton, K.E.4    Grando, S.A.5
  • 78
    • 0041878875 scopus 로고    scopus 로고
    • Differentiation-dependent expression of signal transducers and activators of transcription (STATs) might modify responses to growth factors in the cancers of the head and neck
    • Arany I, Chen SH, Megyesi JK, Adler-Storthz K, Chen Z, Rajaraman S, et al. Differentiation-dependent expression of signal transducers and activators of transcription (STATs) might modify responses to growth factors in the cancers of the head and neck. Cancer Lett 2003; 199:83-89.
    • (2003) Cancer Lett , vol.199 , pp. 83-89
    • Arany, I.1    Chen, S.H.2    Megyesi, J.K.3    Adler-Storthz, K.4    Chen, Z.5    Rajaraman, S.6
  • 79
    • 34248591612 scopus 로고    scopus 로고
    • Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer
    • Roberts PJ, Der CJ. Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer. Oncogene 2007; 26:3291-3310.
    • (2007) Oncogene , vol.26 , pp. 3291-3310
    • Roberts, P.J.1    CJ, D.2
  • 80
    • 0032759393 scopus 로고    scopus 로고
    • Modulatory role of presynaptic nicotinic receptors in synaptic and non-synaptic chemical communication in the central nervous system
    • Vizi ES, Lendavi B. Modulatory role of presynaptic nicotinic receptors in synaptic and non-synaptic chemical communication in the central nervous system. Brain Res Rev 1999; 30:219-235.
    • (1999) Brain Res Rev , vol.30 , pp. 219-235
    • Vizi, E.S.1    Lendavi, B.2
  • 81
    • 77956127888 scopus 로고
    • The preparation of I-131-labelled human growth hormone of high specific radioactivity
    • Greenwood FC, Hunter WM, Glover JS. The preparation of I-131-labelled human growth hormone of high specific radioactivity. Biochem J 1963; 89:114-123.
    • (1963) Biochem J , vol.89 , pp. 114-123
    • Greenwood, F.C.1    Hunter, W.M.2    Glover, J.S.3
  • 82
    • 27744466537 scopus 로고    scopus 로고
    • Bidirectional regulations for glutamate and GABA release in the hippocampus by alpha7 and non-alpha7 ACh receptors
    • Kanno T, Yaguchi T, Yamamoto S, Nagata T, Yamamoto H, Fujikawa H, et al. Bidirectional regulations for glutamate and GABA release in the hippocampus by alpha7 and non-alpha7 ACh receptors. Biochem Biophys Res Commun 2005; 338:742-747.
    • (2005) Biochem Biophys Res Commun , vol.338 , pp. 742-747
    • Kanno, T.1    Yaguchi, T.2    Yamamoto, S.3    Nagata, T.4    Yamamoto, H.5    Fujikawa, H.6
  • 83
    • 33645734603 scopus 로고    scopus 로고
    • N-methyl-D-aspartate receptor type 2B is epigenetically inactivated and exhibits tumor-suppressive activity in human esophageal cancer
    • Kim MS, Yamashita K, Baek JH, Park HL, Carvalho AL, Osada M, et al. N-methyl-D-aspartate receptor type 2B is epigenetically inactivated and exhibits tumor-suppressive activity in human esophageal cancer. Cancer Res 2006; 66:3409-3418.
    • (2006) Cancer Res , vol.66 , pp. 3409-3418
    • Kim, M.S.1    Yamashita, K.2    Baek, J.H.3    Park, H.L.4    Carvalho, A.L.5    Osada, M.6
  • 85
    • 0036859163 scopus 로고    scopus 로고
    • The beta-adrenergic receptors
    • Wallukat G. The beta-adrenergic receptors. Herz 2002; 27:683-690.
    • (2002) Herz , vol.27 , pp. 683-690
    • Wallukat, G.1
  • 86
    • 10644239274 scopus 로고    scopus 로고
    • Sex, GABA, and nicotine: The impact of smoking on cortical GABA levels across the menstrual cycle as measured with proton magnetic resonance spectroscopy
    • Epperson CN, O'Malley S, Czarkowski KA, Gueorguieva R, Jatlow P, Sanacora G, et al. Sex, GABA, and nicotine: the impact of smoking on cortical GABA levels across the menstrual cycle as measured with proton magnetic resonance spectroscopy. Biol Psychiatry 2005; 57:44-48.
    • (2005) Biol Psychiatry , vol.57 , pp. 44-48
    • Epperson, C.N.1    O'Malley, S.2    Czarkowski, K.A.3    Gueorguieva, R.4    Jatlow, P.5    Sanacora, G.6
  • 87
    • 53349145473 scopus 로고    scopus 로고
    • Gamma-aminobutyric acid, a potential tumor suppressor for small airway-derived lung adenocarcinoma
    • Epub ahead of print
    • Schuller HM, Al-Wadei HAN, Majidi M. Gamma-aminobutyric acid, a potential tumor suppressor for small airway-derived lung adenocarcinoma. Carcinogenesis 2008; [Epub ahead of print].
    • (2008) Carcinogenesis
    • Schuller, H.M.1    Al-Wadei, H.A.N.2    Majidi, M.3
  • 88
    • 39049158404 scopus 로고    scopus 로고
    • GABA(B) receptor is a novel drug target for pancreatic cancer
    • Schuller HM, Al-Wadei HA, Majidi M. GABA(B) receptor is a novel drug target for pancreatic cancer. Cancer 2008; 112:767-778.
    • (2008) Cancer , vol.112 , pp. 767-778
    • Schuller, H.M.1    Al-Wadei, H.A.2    Majidi, M.3
  • 89
    • 0025274855 scopus 로고
    • Successful chemotherapy of experimental neuroendocrine lung tumors in hamsters with an antagonist of Ca2+ /calmodulin
    • Schuller HM, Correa E, Orloff M, Reznik GK. Successful chemotherapy of experimental neuroendocrine lung tumors in hamsters with an antagonist of Ca2+ /calmodulin. Cancer Res 1990; 50:1645-1649.
    • (1990) Cancer Res , vol.50 , pp. 1645-1649
    • Schuller, H.M.1    Correa, E.2    Orloff, M.3    Reznik, G.K.4
  • 90
    • 0025918338 scopus 로고
    • Antiproliferative effects of the Ca2+/calmodulin antagonist B859-35 and the Ca(2+)-channel blocker verapamil on human lung cancer cell lines
    • Schuller HM, Orloff M, Reznik GK. Antiproliferative effects of the Ca2+/calmodulin antagonist B859-35 and the Ca(2+)-channel blocker verapamil on human lung cancer cell lines. Carcinogenesis 1991; 12:2301-2303.
    • (1991) Carcinogenesis , vol.12 , pp. 2301-2303
    • Schuller, H.M.1    Orloff, M.2    Reznik, G.K.3
  • 91
    • 0028263224 scopus 로고
    • Inhibition of protein-kinase-C- dependent cell proliferation of human lung cancer cell lines by the dihydropyridine dexniguldipine
    • Schuller HM, Orloff M, Reznik GK. Inhibition of protein-kinase-C- dependent cell proliferation of human lung cancer cell lines by the dihydropyridine dexniguldipine. J Cancer Res Clin Oncol 1994; 120:354-358.
    • (1994) J Cancer Res Clin Oncol , vol.120 , pp. 354-358
    • Schuller, H.M.1    Orloff, M.2    Reznik, G.K.3
  • 92
    • 0037134864 scopus 로고    scopus 로고
    • Protein kinase A balances the growth factor-induced Ras/ERK signaling
    • Pursiheimo JP, Kieksi A, Jalkanen M, Salmivirta M. Protein kinase A balances the growth factor-induced Ras/ERK signaling. FEBS Lett 2002; 521:157-164.
    • (2002) FEBS Lett , vol.521 , pp. 157-164
    • Pursiheimo, J.P.1    Kieksi, A.2    Jalkanen, M.3    Salmivirta, M.4
  • 94
    • 26844456493 scopus 로고    scopus 로고
    • Expression of G-protein inwardly rectifying potassium channels (GIRKs) in lung cancer cell lines
    • Plummer HK III, Dhar MS, Cekanova M, Schuller HM. Expression of G-protein inwardly rectifying potassium channels (GIRKs) in lung cancer cell lines. BMC Cancer 2005; 5:104.
    • (2005) BMC Cancer , vol.5 , pp. 104
    • Plummer III, H.K.1    Dhar, M.S.2    Cekanova, M.3    Schuller, H.M.4
  • 95
    • 0031740825 scopus 로고    scopus 로고
    • Reduced DNA synthesis and cell viability in small cell lung carcinoma by treatment with cyclic AMP phosphodiesterase inhibitors
    • Shafer SH, Phelps SH, Williams CL. Reduced DNA synthesis and cell viability in small cell lung carcinoma by treatment with cyclic AMP phosphodiesterase inhibitors. Biochem Pharmacol 1998; 56:1229-1236.
    • (1998) Biochem Pharmacol , vol.56 , pp. 1229-1236
    • Shafer, S.H.1    Phelps, S.H.2    Williams, C.L.3
  • 96
    • 2942604370 scopus 로고    scopus 로고
    • Neuroendocrine lung carcinogenesis in hamsters is inhibited by green tea or theophylline while the development of adenocarcinomas is promoted: Implications for chemoprevention in smokers
    • Schuller HM, Porter B, Riechert A, Walker K, Schmoyer R. Neuroendocrine lung carcinogenesis in hamsters is inhibited by green tea or theophylline while the development of adenocarcinomas is promoted: implications for chemoprevention in smokers. Lung Cancer 2004; 45:11-18.
    • (2004) Lung Cancer , vol.45 , pp. 11-18
    • Schuller, H.M.1    Porter, B.2    Riechert, A.3    Walker, K.4    Schmoyer, R.5
  • 97
    • 34248597724 scopus 로고    scopus 로고
    • M3 muscarinic receptor antagonists inhibit small cell lung carcinoma growth and mitogen-activated protein kinase phosphorylation induced by acetylcholine secretion
    • Song P, Sekhon HS, Lu A, Arredondo J, Sauer D, Gravett C, et al. M3 muscarinic receptor antagonists inhibit small cell lung carcinoma growth and mitogen-activated protein kinase phosphorylation induced by acetylcholine secretion. Cancer Res 2007; 67:3936-3944.
    • (2007) Cancer Res , vol.67 , pp. 3936-3944
    • Song, P.1    Sekhon, H.S.2    Lu, A.3    Arredondo, J.4    Sauer, D.5    Gravett, C.6
  • 100
    • 6444241107 scopus 로고    scopus 로고
    • Role of the non-neuronal human cholinergic system in lung cancer and mesothelioma: Possibility of new therapeutic strategies
    • Trombino S, Bisio A, Catassi A, Cesario A, Falugi C, Russo P. Role of the non-neuronal human cholinergic system in lung cancer and mesothelioma: possibility of new therapeutic strategies. Curr Med Chem Anticancer Agents 2004; 4:535-542.
    • (2004) Curr Med Chem Anticancer Agents , vol.4 , pp. 535-542
    • Trombino, S.1    Bisio, A.2    Catassi, A.3    Cesario, A.4    Falugi, C.5    Russo, P.6
  • 101
    • 0142188718 scopus 로고    scopus 로고
    • Transactivation of the epidermal growth factor receptor mediates cholinergic agonist-induced proliferation of H508 human colon cancer cells
    • Cheng K, Zimniak P, Raufman JP. Transactivation of the epidermal growth factor receptor mediates cholinergic agonist-induced proliferation of H508 human colon cancer cells. Cancer Res 2003; 63:6744-6750.
    • (2003) Cancer Res , vol.63 , pp. 6744-6750
    • Cheng, K.1    Zimniak, P.2    Raufman, J.P.3
  • 103
    • 0031979184 scopus 로고    scopus 로고
    • Analysis of cell type and radiographic presentation as predictors of the clinical course of patients with bronchioalveolar cell carcinoma
    • Albertine KH, Steiner RM, Radack DM, Golding DM, Peterson D, Cohn HE, et al. Analysis of cell type and radiographic presentation as predictors of the clinical course of patients with bronchioalveolar cell carcinoma. Chest 1998; 113:997-1006.
    • (1998) Chest , vol.113 , pp. 997-1006
    • Albertine, K.H.1    Steiner, R.M.2    Radack, D.M.3    Golding, D.M.4    Peterson, D.5    Cohn, H.E.6
  • 105
    • 0025785811 scopus 로고
    • Mutations of ras genes distinguish a subset of non-small-cell lung cancer cell lines from small-cell lung cancer cell lines
    • Mitsudomi T, Viallet J, Mulshine JL, Linnoila RI, Minna JD, Gazdar AF. Mutations of ras genes distinguish a subset of non-small-cell lung cancer cell lines from small-cell lung cancer cell lines. Oncogene 1991; 6:1353-1362.
    • (1991) Oncogene , vol.6 , pp. 1353-1362
    • Mitsudomi, T.1    Viallet, J.2    Mulshine, J.L.3    Linnoila, R.I.4    Minna, J.D.5    Gazdar, A.F.6
  • 106
    • 0032170955 scopus 로고    scopus 로고
    • Increased expression of cyclooxygenase 2 occurs frequently in human lung cancers, specifically in adenocarcinomas
    • Hida T, Yatabe Y, Achiwa H, Muramatsu H, Kozaki K, Nakamura S, et al. Increased expression of cyclooxygenase 2 occurs frequently in human lung cancers, specifically in adenocarcinomas. Cancer Res 1998; 58:3761-3764.
    • (1998) Cancer Res , vol.58 , pp. 3761-3764
    • Hida, T.1    Yatabe, Y.2    Achiwa, H.3    Muramatsu, H.4    Kozaki, K.5    Nakamura, S.6
  • 108
    • 0019428947 scopus 로고
    • Comparative carcinogenicity and metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and N′-nitrosonornicotine in Syrian golden hamsters
    • Hoffmann D, Castonguay A, Rivenson A, Hecht SS. Comparative carcinogenicity and metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and N′-nitrosonornicotine in Syrian golden hamsters. Cancer Res 1981; 41:2386-2393.
    • (1981) Cancer Res , vol.41 , pp. 2386-2393
    • Hoffmann, D.1    Castonguay, A.2    Rivenson, A.3    Hecht, S.S.4
  • 109
    • 0017032865 scopus 로고
    • Ultrastructural alterations of nonciliated cells after nitrosamine treatment and their significance for pulmonary carcinogenesis
    • Reznik-Schuller H. Ultrastructural alterations of nonciliated cells after nitrosamine treatment and their significance for pulmonary carcinogenesis. Am J Pathol 1976; 85:549-554.
    • (1976) Am J Pathol , vol.85 , pp. 549-554
    • Reznik-Schuller, H.1
  • 110
    • 0026697154 scopus 로고
    • Role of the alveolar type II cell in the development and progression of pulmonary tumors induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in the A/J mouse
    • Belinsky SA, Devereux TR, Foley JF, Maronpot RR, Anderson MW. Role of the alveolar type II cell in the development and progression of pulmonary tumors induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in the A/J mouse. Cancer Res 1992; 52:3164-3173.
    • (1992) Cancer Res , vol.52 , pp. 3164-3173
    • Belinsky, S.A.1    Devereux, T.R.2    Foley, J.F.3    Maronpot, R.R.4    Anderson, M.W.5
  • 111
    • 0025978602 scopus 로고
    • Origin of spontaneous and transplacentally induced mouse lung tumors from alveolar type II cells
    • Rehm S, Devor DE, Henneman JR, Ward JM. Origin of spontaneous and transplacentally induced mouse lung tumors from alveolar type II cells. Exp Lung Res 1991; 17:181-195.
    • (1991) Exp Lung Res , vol.17 , pp. 181-195
    • Rehm, S.1    Devor, D.E.2    Henneman, J.R.3    Ward, J.M.4
  • 112
    • 0025965491 scopus 로고
    • Role of Clara cells and type II cells in the development of pulmonary tumors in rats and mice following exposure to a tobacco-specific nitrosamine
    • Belinsky SA, Devereux TR, White CM, Foley JF, Maronpot RR, Anderson MW. Role of Clara cells and type II cells in the development of pulmonary tumors in rats and mice following exposure to a tobacco-specific nitrosamine. Exp Lung Res 1991; 17:263-278.
    • (1991) Exp Lung Res , vol.17 , pp. 263-278
    • Belinsky, S.A.1    Devereux, T.R.2    White, C.M.3    Foley, J.F.4    Maronpot, R.R.5    Anderson, M.W.6
  • 113
    • 11144355464 scopus 로고    scopus 로고
    • Classification of proliferative pulmonary lesions of the mouse: Recommendations of the mouse models of human cancers consortium
    • Nikitin AY, Alcaraz A, Anver MR, Bronson RT, Cardiff RD, Dixon D, et al. Classification of proliferative pulmonary lesions of the mouse: recommendations of the mouse models of human cancers consortium. Cancer Res 2004; 64:2307-2316.
    • (2004) Cancer Res , vol.64 , pp. 2307-2316
    • Nikitin, A.Y.1    Alcaraz, A.2    Anver, M.R.3    Bronson, R.T.4    Cardiff, R.D.5    Dixon, D.6
  • 114
    • 16544364039 scopus 로고    scopus 로고
    • Antagonistic growth regulation of cell lines derived from human lung adenocarcinomas of Clara cell and aveolar type II cell lineage:implications for chemoprevention
    • Adissu HA, Schuller HM. Antagonistic growth regulation of cell lines derived from human lung adenocarcinomas of Clara cell and aveolar type II cell lineage:implications for chemoprevention. Int J Oncol 2004; 24:1467-1472.
    • (2004) Int J Oncol , vol.24 , pp. 1467-1472
    • Adissu, H.A.1    Schuller, H.M.2
  • 115
    • 0028979841 scopus 로고
    • Beta-adrenergic mitogenic signal transduction in peripheral lung adenocarcinoma:implications for individuals with preexisting chronic lung disease
    • Park PG, Merryman J, Orloff M, Schuller HM. Beta-adrenergic mitogenic signal transduction in peripheral lung adenocarcinoma:implications for individuals with preexisting chronic lung disease. Cancer Res 1995; 55:3504-3508.
    • (1995) Cancer Res , vol.55 , pp. 3504-3508
    • Park, P.G.1    Merryman, J.2    Orloff, M.3    Schuller, H.M.4
  • 116
    • 33747450166 scopus 로고    scopus 로고
    • NNK activates ERK1/2 and CREB/ATF-1 via beta-AR and EGFR signaling in human lung adenocarcinoma and small airway epithelial cells
    • Laag EM, Majidi M, Cekanova M, Masi T, Takahashi T, Schuller HM. NNK activates ERK1/2 and CREB/ATF-1 via beta-AR and EGFR signaling in human lung adenocarcinoma and small airway epithelial cells. Int J Cancer 2006; 119:1547-1552.
    • (2006) Int J Cancer , vol.119 , pp. 1547-1552
    • Laag, E.M.1    Majidi, M.2    Cekanova, M.3    Masi, T.4    Takahashi, T.5    Schuller, H.M.6
  • 117
    • 0033784638 scopus 로고    scopus 로고
    • Beta-adrenergic modulation of NNK-induced lung carcinogenesis in hamsters
    • Schuller HM, Porter B, Riechert A. Beta-adrenergic modulation of NNK-induced lung carcinogenesis in hamsters. J Cancer Res Clin Oncol 2000; 126:624-630.
    • (2000) J Cancer Res Clin Oncol , vol.126 , pp. 624-630
    • Schuller, H.M.1    Porter, B.2    Riechert, A.3
  • 118
    • 20444380009 scopus 로고    scopus 로고
    • NNK-induced hamster lung adenocarcinomas over-express beta2-adrenergic and EGFR signaling pathways
    • Schuller HM, Cekanova M. NNK-induced hamster lung adenocarcinomas over-express beta2-adrenergic and EGFR signaling pathways. Lung Cancer 2005; 49:35-45.
    • (2005) Lung Cancer , vol.49 , pp. 35-45
    • Schuller, H.M.1    Cekanova, M.2
  • 119
    • 0036532167 scopus 로고    scopus 로고
    • Human non-small cell lung tumors and cells derived from normal lung express both estrogen receptor alpha and beta and show biological responses to estrogen
    • Stabile LP, Davis AL, Gubish CT, Hopkins TM, Luketich JD, Christie N, et al. Human non-small cell lung tumors and cells derived from normal lung express both estrogen receptor alpha and beta and show biological responses to estrogen. Cancer Res 2002; 62:2141-2150.
    • (2002) Cancer Res , vol.62 , pp. 2141-2150
    • Stabile, L.P.1    Davis, A.L.2    Gubish, C.T.3    Hopkins, T.M.4    Luketich, J.D.5    Christie, N.6
  • 120
    • 0035831020 scopus 로고    scopus 로고
    • Nongenotropic, sex-nonspecific signaling through the estrogen or androgen receptors:dissociation from transcriptional activity
    • Kousteni S, Bellido T, Plotkin LI, O'Brien CA, Bodenner DL, Han L, et al. Nongenotropic, sex-nonspecific signaling through the estrogen or androgen receptors:dissociation from transcriptional activity. Cell 2001; 104:719-730.
    • (2001) Cell , vol.104 , pp. 719-730
    • Kousteni, S.1    Bellido, T.2    Plotkin, L.I.3    O'Brien, C.A.4    Bodenner, D.L.5    Han, L.6
  • 121
    • 13944265574 scopus 로고    scopus 로고
    • Combined targeting of the estrogen receptor and the epidermal growth factor receptor in non-small cell lung cancer shows enhanced antiproliferative effects
    • Stabile LP, Lyker JS, Gubish CT, Zhang W, Grandis JR, Siegfried JM. Combined targeting of the estrogen receptor and the epidermal growth factor receptor in non-small cell lung cancer shows enhanced antiproliferative effects. Cancer Res 2005; 65:1459-1470.
    • (2005) Cancer Res , vol.65 , pp. 1459-1470
    • Stabile, L.P.1    Lyker, J.S.2    Gubish, C.T.3    Zhang, W.4    Grandis, J.R.5    Siegfried, J.M.6
  • 122
    • 34547116879 scopus 로고    scopus 로고
    • Nongenomic beta estrogen receptors enhance beta1 adrenergic signaling induced by the nicotine-derived carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in human small airway epithelial cells
    • Majidi M, Al-Wadei HA, Takahashi T, Schuller HM. Nongenomic beta estrogen receptors enhance beta1 adrenergic signaling induced by the nicotine-derived carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in human small airway epithelial cells. Cancer Res 2007; 67:6863-6871.
    • (2007) Cancer Res , vol.67 , pp. 6863-6871
    • Majidi, M.1    Al-Wadei, H.A.2    Takahashi, T.3    Schuller, H.M.4
  • 123
    • 0030776845 scopus 로고    scopus 로고
    • Women and lung cancer:waiting to exhale
    • Baldini EH, Strauss GM. Women and lung cancer:waiting to exhale. Chest 1997; 112:229S-234S.
    • (1997) Chest , vol.112
    • Baldini, E.H.1    Strauss, G.M.2
  • 124
    • 0034836642 scopus 로고    scopus 로고
    • Norepinephrine induces alveolar epithelial apoptosis mediated by alpha-, beta-, and angiotensin receptor activation
    • Dincer HE, Gangopadhyay N, Wang R, Uhal BD. Norepinephrine induces alveolar epithelial apoptosis mediated by alpha-, beta-, and angiotensin receptor activation. Am J Physiol Lung Cell Mol Physiol 2001; 281:L624-L630.
    • (2001) Am J Physiol Lung Cell Mol Physiol , vol.281
    • Dincer, H.E.1    Gangopadhyay, N.2    Wang, R.3    Uhal, B.D.4
  • 125
    • 0032530259 scopus 로고    scopus 로고
    • Inhibition of lung carcinogenesis by black tea in Fischer rats treated with a tobacco-specific carcinogen:caffeine as an important constituent
    • Chung FL, Wang M, Rivenson A, Iatropoulos MJ, Reinhardt JC, Pittman B, et al. Inhibition of lung carcinogenesis by black tea in Fischer rats treated with a tobacco-specific carcinogen:caffeine as an important constituent. Cancer Res 1998; 58:4096-4101.
    • (1998) Cancer Res , vol.58 , pp. 4096-4101
    • Chung, F.L.1    Wang, M.2    Rivenson, A.3    Iatropoulos, M.J.4    Reinhardt, J.C.5    Pittman, B.6
  • 127
    • 0025181809 scopus 로고
    • Risk factors of cancer of the pancreas from analytic epidemiologic studies
    • Raymond L, Bouchardy C. Risk factors of cancer of the pancreas from analytic epidemiologic studies. Bull Cancer 1990; 77:47-68.
    • (1990) Bull Cancer , vol.77 , pp. 47-68
    • Raymond, L.1    Bouchardy, C.2
  • 129
    • 0024262907 scopus 로고
    • Induction of lung and exocrine pancreas tumors in F344 rats by tobacco-specific and areca-derived N-nitrosamines
    • Rivenson A, Hoffmann D, Prokopczyk B, Amin S, Hecht SS. Induction of lung and exocrine pancreas tumors in F344 rats by tobacco-specific and areca-derived N-nitrosamines. Cancer Res 1988; 48:6912-6917.
    • (1988) Cancer Res , vol.48 , pp. 6912-6917
    • Rivenson, A.1    Hoffmann, D.2    Prokopczyk, B.3    Amin, S.4    Hecht, S.S.5
  • 130
    • 0027240991 scopus 로고
    • Transplacental induction of pancreas tumors in hamsters by ethanol and the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone
    • Schuller HM, Jorquera R, Reichert A, Castonguay A. Transplacental induction of pancreas tumors in hamsters by ethanol and the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Cancer Res 1993; 53:2498-2501.
    • (1993) Cancer Res , vol.53 , pp. 2498-2501
    • Schuller, H.M.1    Jorquera, R.2    Reichert, A.3    Castonguay, A.4
  • 131
    • 0036033780 scopus 로고    scopus 로고
    • The cyclooxygenase inhibitor ibuprofen and the FLAP inhibitor MK886 inhibit pancreatic carcinogenesis induced in hamsters by transplacental exposure to ethanol and the tobacco carcinogen NNK
    • Schuller HM, Zhang L, Weddle DL, Castonguay A, Walker K, Miller MS. The cyclooxygenase inhibitor ibuprofen and the FLAP inhibitor MK886 inhibit pancreatic carcinogenesis induced in hamsters by transplacental exposure to ethanol and the tobacco carcinogen NNK. J Cancer Res Clin Oncol 2002; 128:525-532.
    • (2002) J Cancer Res Clin Oncol , vol.128 , pp. 525-532
    • Schuller, H.M.1    Zhang, L.2    Weddle, D.L.3    Castonguay, A.4    Walker, K.5    Miller, M.S.6
  • 132
    • 0035098423 scopus 로고    scopus 로고
    • Beta-adrenergic growth regulation of human cancer cell lines derived from pancreatic ductal carcinomas
    • Weddle DL, Tithoff P, Williams M, Schuller HM. Beta-adrenergic growth regulation of human cancer cell lines derived from pancreatic ductal carcinomas. Carcinogenesis 2001; 22:473-479.
    • (2001) Carcinogenesis , vol.22 , pp. 473-479
    • Weddle, D.L.1    Tithoff, P.2    Williams, M.3    Schuller, H.M.4
  • 133
    • 39049158404 scopus 로고    scopus 로고
    • GABA(B) receptor is a novel drug target for pancreatic cancer
    • Schuller HM, Al-Wadei HA, Majidi M. GABA(B) receptor is a novel drug target for pancreatic cancer. Cancer 2007; 112:767-778.
    • (2007) Cancer , vol.112 , pp. 767-778
    • Schuller, H.M.1    Al-Wadei, H.A.2    Majidi, M.3
  • 134
    • 27144434360 scopus 로고    scopus 로고
    • The tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone stimulates proliferation of immortalized human pancreatic duct epithelia through beta-adrenergic transactivation of EGF receptors
    • Askari MD, Tsao MS, Schuller HM. The tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone stimulates proliferation of immortalized human pancreatic duct epithelia through beta-adrenergic transactivation of EGF receptors. J Cancer Res Clin Oncol 2005; 131:639-648.
    • (2005) J Cancer Res Clin Oncol , vol.131 , pp. 639-648
    • Askari, M.D.1    Tsao, M.S.2    Schuller, H.M.3
  • 135
    • 33745684935 scopus 로고    scopus 로고
    • Ethanol and the tobacco-specific carcinogen, NNK, contribute to signaling in immortalized human pancreatic duct epithelial cells
    • Askari MD, Tsao MS, Cekanova M, Schuller HM. Ethanol and the tobacco-specific carcinogen, NNK, contribute to signaling in immortalized human pancreatic duct epithelial cells. Pancreas 2006; 33:53-62.
    • (2006) Pancreas , vol.33 , pp. 53-62
    • Askari, M.D.1    Tsao, M.S.2    Cekanova, M.3    Schuller, H.M.4
  • 136
    • 0036654586 scopus 로고    scopus 로고
    • Beta-adrenergic and arachidonic acid-mediated growth regulation of human breast cancer cell lines
    • Cakir Y, Plummer HK III, Tithof PK, Schuller HM. Beta-adrenergic and arachidonic acid-mediated growth regulation of human breast cancer cell lines. Int J Oncol 2002; 21:153-157.
    • (2002) Int J Oncol , vol.21 , pp. 153-157
    • Cakir, Y.1    Plummer III, H.K.2    Tithof, P.K.3    Schuller, H.M.4
  • 137
    • 13144288185 scopus 로고    scopus 로고
    • Expression of inwardly rectifying potassium channels (GIRKs) and beta-adrenergic regulation of breast cancer cell lines
    • Plummer HK III, Yu Q, Cakir Y, Schuller HM. Expression of inwardly rectifying potassium channels (GIRKs) and beta-adrenergic regulation of breast cancer cell lines. BMC Cancer 2004; 4:93.
    • (2004) BMC Cancer , vol.4 , pp. 93
    • Plummer III, H.K.1    Yu, Q.2    Cakir, Y.3    Schuller, H.M.4
  • 138
    • 0035863557 scopus 로고    scopus 로고
    • Overexpression of the G-protein inwardly rectifying potassium channel 1 (GIRK1) in primary breast carcinomas correlates with axillary lymph node metastasis
    • Stringer BK, Cooper AG, Shepard SB. Overexpression of the G-protein inwardly rectifying potassium channel 1 (GIRK1) in primary breast carcinomas correlates with axillary lymph node metastasis. Cancer Res 2001; 61:582-588.
    • (2001) Cancer Res , vol.61 , pp. 582-588
    • Stringer, B.K.1    Cooper, A.G.2    Shepard, S.B.3
  • 141
    • 0034727893 scopus 로고    scopus 로고
    • Pharmacological modulation of nerve growth factor synthesis:a mechanistic comparison of vitamin D receptor and beta(2)-adrenoceptor agonists
    • Samina Riaz S, Tomlinson DR. Pharmacological modulation of nerve growth factor synthesis:a mechanistic comparison of vitamin D receptor and beta(2)-adrenoceptor agonists. Brain Res Mol Brain Res 2000; 85:179-188.
    • (2000) Brain Res Mol Brain Res , vol.85 , pp. 179-188
    • Samina Riaz, S.1    Tomlinson, D.R.2
  • 142
    • 0032971356 scopus 로고    scopus 로고
    • NGF mediates the neuroprotective effect of the beta2-adrenoceptor agonist clenbuterol in vitro and in vivo:evidence from an NGF-antisense study
    • Culmsee C, Semkova I, Krieglstein J. NGF mediates the neuroprotective effect of the beta2-adrenoceptor agonist clenbuterol in vitro and in vivo:evidence from an NGF-antisense study. Neurochem Int 1999; 35:47-57.
    • (1999) Neurochem Int , vol.35 , pp. 47-57
    • Culmsee, C.1    Semkova, I.2    Krieglstein, J.3
  • 143
    • 0034124607 scopus 로고    scopus 로고
    • Beta-adrenoreceptor signaling and its control of cell replication in MDA-MB-231 human breast cancer cells
    • Slotkin TA, Zhang J, Dancel R, Garcia SJ, Willis C, Seidler FJ. Beta-adrenoreceptor signaling and its control of cell replication in MDA-MB-231 human breast cancer cells. Breast Cancer Treat 2000; 60:153-166.
    • (2000) Breast Cancer Treat , vol.60 , pp. 153-166
    • Slotkin, T.A.1    Zhang, J.2    Dancel, R.3    Garcia, S.J.4    Willis, C.5    Seidler, F.J.6
  • 144
    • 0033654025 scopus 로고    scopus 로고
    • Effects of alpha(1)-adrenoceptor (alpha(1)-AR) antagonists on cell proliferation and apoptosis in the prostate:therapeutic implications in prostatic disease
    • Kyprianou N, Chon J, Benning CM. Effects of alpha(1)-adrenoceptor (alpha(1)-AR) antagonists on cell proliferation and apoptosis in the prostate:therapeutic implications in prostatic disease. Prostate Suppl 2000; 9:42-46.
    • (2000) Prostate Suppl , vol.9 , pp. 42-46
    • Kyprianou, N.1    Chon, J.2    Benning, C.M.3
  • 145
    • 4544321026 scopus 로고    scopus 로고
    • Induction of a metastatogenic tumor cell type by neurotransmitters and its pharmacological inhibition by established drugs
    • Lang K, Drell TL, Lindecke A, Niggemann B, Kaltschmidt C, Zaenker KS, et al. Induction of a metastatogenic tumor cell type by neurotransmitters and its pharmacological inhibition by established drugs. Int J Cancer 2004; 112:231-238.
    • (2004) Int J Cancer , vol.112 , pp. 231-238
    • Lang, K.1    Drell, T.L.2    Lindecke, A.3    Niggemann, B.4    Kaltschmidt, C.5    Zaenker, K.S.6
  • 146
    • 33646371479 scopus 로고    scopus 로고
    • The norepinephrine-driven metastasis development of PC-3 human prostate cancer cells in BALB/c nude mice is inhibited by beta-blockers
    • Palm D, Lang K, Niggemann B, Drell TL, Masur K, Zaenker KS, et al. The norepinephrine-driven metastasis development of PC-3 human prostate cancer cells in BALB/c nude mice is inhibited by beta-blockers. Int J Cancer 2006; 118:2744-2749.
    • (2006) Int J Cancer , vol.118 , pp. 2744-2749
    • Palm, D.1    Lang, K.2    Niggemann, B.3    Drell, T.L.4    Masur, K.5    Zaenker, K.S.6
  • 147
    • 4043163432 scopus 로고    scopus 로고
    • Antihypertensive drug use and the risk of prostate cancer (Canada)
    • Perron L, Bairati I, Harel F, Meyer F. Antihypertensive drug use and the risk of prostate cancer (Canada). Cancer Causes Control 2004; 15:535-541.
    • (2004) Cancer Causes Control , vol.15 , pp. 535-541
    • Perron, L.1    Bairati, I.2    Harel, F.3    Meyer, F.4
  • 148
    • 35148888509 scopus 로고    scopus 로고
    • Effect of alpha1-adrenoceptor antagonist exposure on prostate cancer incidence:an observational cohort study
    • Harris AM, Warner BW, Wilson JM, Becker A, Rowland RG, Conner W, et al. Effect of alpha1-adrenoceptor antagonist exposure on prostate cancer incidence:an observational cohort study. J Urol 2007; 178:2176-2180.
    • (2007) J Urol , vol.178 , pp. 2176-2180
    • Harris, A.M.1    Warner, B.W.2    Wilson, J.M.3    Becker, A.4    Rowland, R.G.5    Conner, W.6
  • 149
    • 0035300538 scopus 로고    scopus 로고
    • Norepinephrine-induced migration of SW 480 colon carcinoma cells is inhibited by beta-blockers
    • Masur K, Niggemann B, Zanker KS, Entschladen F. Norepinephrine-induced migration of SW 480 colon carcinoma cells is inhibited by beta-blockers. Cancer Res 2001; 61:2866-2869.
    • (2001) Cancer Res , vol.61 , pp. 2866-2869
    • Masur, K.1    Niggemann, B.2    Zanker, K.S.3    Entschladen, F.4
  • 150
    • 0345866851 scopus 로고    scopus 로고
    • Nicotine promoted colon cancer growth via epidermal growth factor receptor, c-Src, and 5-lipoxygenase-mediated signal pathway
    • Ye YN, Liu ES, Shin VY, Wu WK, Luo JC, Cho CH. Nicotine promoted colon cancer growth via epidermal growth factor receptor, c-Src, and 5-lipoxygenase-mediated signal pathway. J Pharmacol Exp Ther 2004; 308:66-72.
    • (2004) J Pharmacol Exp Ther , vol.308 , pp. 66-72
    • Ye, Y.N.1    Liu, E.S.2    Shin, V.Y.3    Wu, W.K.4    Luo, J.C.5    Cho, C.H.6
  • 152
    • 33746851955 scopus 로고    scopus 로고
    • Chronic stress promotes tumor growth and angiogenesis in a mouse model of ovarian carcinoma
    • Thaker PH, Han LY, Kamat AA, Arevalo JM, Takahashi R, Lu C, et al. Chronic stress promotes tumor growth and angiogenesis in a mouse model of ovarian carcinoma. Nat Med 2006; 12:939-944.
    • (2006) Nat Med , vol.12 , pp. 939-944
    • Thaker, P.H.1    Han, L.Y.2    Kamat, A.A.3    Arevalo, J.M.4    Takahashi, R.5    Lu, C.6
  • 153
    • 0036045686 scopus 로고    scopus 로고
    • Psychological stress augments tumor development through beta-adrenergic activation in mice
    • Hasegawa H, Saiki I. Psychological stress augments tumor development through beta-adrenergic activation in mice. Jpn J Cancer Res 2002; 93:729-735.
    • (2002) Jpn J Cancer Res , vol.93 , pp. 729-735
    • Hasegawa, H.1    Saiki, I.2
  • 154
    • 33645281462 scopus 로고    scopus 로고
    • Signalling pathways evoked by alpha1-adrenoceptors in human melanoma cells
    • Scarparo AC, Visconti MA, Castrucci AM. Signalling pathways evoked by alpha1-adrenoceptors in human melanoma cells. Cell Biochem Funct 2006; 24:119-129.
    • (2006) Cell Biochem Funct , vol.24 , pp. 119-129
    • Scarparo, A.C.1    Visconti, M.A.2    Castrucci, A.M.3
  • 155
    • 0036592038 scopus 로고    scopus 로고
    • Stimulation of alpha-1-adrenergic receptor inhibits cholangiocarcinoma growth through modulation of Raf-1 and B-Raf activities
    • Kanno N, Lesage G, Phinizy JL, Glaser S, Francis H, Alpini G. Stimulation of alpha-1-adrenergic receptor inhibits cholangiocarcinoma growth through modulation of Raf-1 and B-Raf activities. Hepatology 2002; 35:1329-1340.
    • (2002) Hepatology , vol.35 , pp. 1329-1340
    • Kanno, N.1    Lesage, G.2    Phinizy, J.L.3    Glaser, S.4    Francis, H.5    Alpini, G.6
  • 156
    • 0033680985 scopus 로고    scopus 로고
    • Beta-adrenergic receptor/cAMP-mediated signaling and apoptosis of S49 lymphoma cells
    • Yan L, Herrmann V, Hofer JK, Insel PA. Beta-adrenergic receptor/cAMP-mediated signaling and apoptosis of S49 lymphoma cells. Am J Physiol Cell Physiol 2000; 279:1665-1674.
    • (2000) Am J Physiol Cell Physiol , vol.279 , pp. 1665-1674
    • Yan, L.1    Herrmann, V.2    Hofer, J.K.3    Insel, P.A.4
  • 157
    • 14544307015 scopus 로고    scopus 로고
    • History and the present of metabotropic GABAB receptor
    • Franek M. History and the present of metabotropic GABAB receptor. Cesk Fysiol 2004; 53:117-124.
    • (2004) Cesk Fysiol , vol.53 , pp. 117-124
    • Franek, M.1
  • 159
    • 20444449329 scopus 로고    scopus 로고
    • 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone from cigarette smoke stimulates colon cancer growth via beta-adrenoceptors
    • Wu WK, Wong HP, Luo SW, Chan K, Huang FY, Hui MK, et al. 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone from cigarette smoke stimulates colon cancer growth via beta-adrenoceptors. Cancer Res 2005; 65:5272-5277.
    • (2005) Cancer Res , vol.65 , pp. 5272-5277
    • Wu, W.K.1    Wong, H.P.2    Luo, S.W.3    Chan, K.4    Huang, F.Y.5    Hui, M.K.6
  • 160
    • 0037112519 scopus 로고    scopus 로고
    • The neurotransmitter gamma-aminobutyric acid is an inhibitory regulator for the migration of SW 480 colon carcinoma cells
    • Joseph J, Niggemann B, Zaenker KS, Entschladen F. The neurotransmitter gamma-aminobutyric acid is an inhibitory regulator for the migration of SW 480 colon carcinoma cells. Cancer Res 2002; 62:6467-6469.
    • (2002) Cancer Res , vol.62 , pp. 6467-6469
    • Joseph, J.1    Niggemann, B.2    Zaenker, K.S.3    Entschladen, F.4
  • 161
    • 33644521306 scopus 로고    scopus 로고
    • The peripheral GABAergic system as a target in endocrine disorders
    • Gladkevich A, Korf J, Hakobyan KV. The peripheral GABAergic system as a target in endocrine disorders. Auton Neurosci 2006; 124:1-8.
    • (2006) Auton Neurosci , vol.124 , pp. 1-8
    • Gladkevich, A.1    Korf, J.2    Hakobyan, K.V.3
  • 162
    • 35448969671 scopus 로고    scopus 로고
    • Gamma-aminobutyric acid (GABA) stimulates pancreatic cancer growth through overexpressing GABAA receptor pi subunit
    • Takehara A, Hosokawa M, Eguchi H, Ohigashi H, Ishikawa O, Nakamura Y, et al. Gamma-aminobutyric acid (GABA) stimulates pancreatic cancer growth through overexpressing GABAA receptor pi subunit. Cancer Res 2007; 67:9704-9712.
    • (2007) Cancer Res , vol.67 , pp. 9704-9712
    • Takehara, A.1    Hosokawa, M.2    Eguchi, H.3    Ohigashi, H.4    Ishikawa, O.5    Nakamura, Y.6
  • 163
    • 1842423821 scopus 로고    scopus 로고
    • Effects of germinated brown rice extracts with enhanced levels of GABA on cancer cell proliferation and apoptosis
    • Oh CH, Oh SH. Effects of germinated brown rice extracts with enhanced levels of GABA on cancer cell proliferation and apoptosis. J Med Food 2004; 7:18-23.
    • (2004) J Med Food , vol.7 , pp. 18-23
    • Oh, C.H.1    Oh, S.H.2
  • 164
    • 0031825309 scopus 로고    scopus 로고
    • GABA content and GAD activity in colon tumors taken from patients with colon cancer or from xenografted human colon cancer cells growing as s.c. tumors in athymic nu/nu mice
    • Kleinrok Z, Matuszek M, Jesipowicz J, Matuszek B, Opolski A, Radzikowski C. GABA content and GAD activity in colon tumors taken from patients with colon cancer or from xenografted human colon cancer cells growing as s.c. tumors in athymic nu/nu mice. J Physiol Pharmacol 1998; 49:303-310.
    • (1998) J Physiol Pharmacol , vol.49 , pp. 303-310
    • Kleinrok, Z.1    Matuszek, M.2    Jesipowicz, J.3    Matuszek, B.4    Opolski, A.5    Radzikowski, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.