Neuroepithelial bodies as airway oxygen sensors

Respiration Physiology

Volumn 115, Issue 2, 1999, Pages 201-214

  Cutz, Ernest ^a   Jackson, Adele ^a  

^a Dept Paediatr Lab Med Res I ^*  (Canada)

Author keywords

Airway chemoreceptors; NADPH oxidase; Neuroepithelial bodies; O2 sensitive K+ current; Pediatric pulmonary disorders

Indexed keywords

OXYGEN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

AIRWAY; ANIMAL TISSUE; CAROTID BODY; CHEMORECEPTOR; CONFERENCE PAPER; CONTROLLED STUDY; ELECTROPHYSIOLOGY; FETUS; HAMSTER; HYPOXIA; IMMUNOHISTOCHEMISTRY; ION CURRENT; LUNG; LUNG DISEASE; MODEL; NEUROEPITHELIUM; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; RABBIT; RAT; SCANNING ELECTRON MICROSCOPY; SENSOR;

ANIMALS; ANOXIA; CHEMORECEPTORS; HUMANS; INFANT, NEWBORN; LUNG; LUNG DISEASES; MODELS, NEUROLOGICAL; OXYGEN; SIGNAL TRANSDUCTION;

EID: 0033004626     PISSN: 00345687     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0034-5687(99)00018-3     Document Type: Conference Paper

References (57)

1. 2 chemoreception. J. Auton. Nerv. Syst. 41:1992;41-52.
2. 2-sensing cells. NIPS. 10:1995;211-216.
3. Adriaensen D., Scheuermann D.W. Neuroendocrine cells and nerves of the lung. Anat. Rec. 236:1993;70-85.
4. Adriaensen D., Timmermans J.-P., Brouns I., Berthoud H.-R., Neuhuber W.L., Scheuermann D.W. Vagal afferent innervation of pulmonary neuroepithelial bodies (NEBs) revealed by anterograde tracing and confocal microscopy. J. Auton. Nerv. Syst. 65:1997;153.
5. 2 sensor protein in the rat carotid body. Biochem. J. 272:1990;743-747.
6. Cross A.R., Jones O.T.G. Enzymatic mechanisms of superoxide production. Biochem. Biophys. Acta. 1057:1991;281-298.
7. Cutz E., Gillan J.E., Track N.S. Pulmonary endocrine cells in developing human lung and during neonatal adaptation. Becker K.L., Gazdar A.F. The Endocrine Lung in Health and Disease. 1984;210-231 Saunders, PA.
8. 2+ ionophore on serotonin content and exocytosis of dense core vesicles. Anat. Rec. 236:1993;41-52.
9. Cutz E., Gillan J.E., Perrin D.G. Pulmonary neuroendocrine system: an overview of cell biology and pathology with emphasis on pediatric lung disease. Askin F.B., Langston C., Rosenberg H.S., Bernstein J. Pulmonary Disease. 1995;32-70 Karger, Basel.
10. Cutz E., Perrin D.G., Hackman R., Czegledy-Nagy E.N. Maternal smoking and pulmonary neuroendocrine cells in sudden infant death syndrome. Pediatrics. 98:1996;668-672.
11. Cutz E. Studies on neuroepithelial bodies under experimental and disease conditions. Cutz E. Cellular and Molecular Biology of Airway Chemoreceptors. 1997;109-129 Landes Bioscience, Texas.
12. Cutz E., Ma T.K.F., Perrin D.G., Moore A.M., Becker L.E. Peripheral chemoreceptors in congenital central hypoventilation syndrome. Am. J. Respir. Crit. Care Med. 155:1997;358-363.
13. Dhillon D.P., Barer G.R., Walsh M. The enlarged carotid body of the chronically hypoxic and chronic hypoxic and hypercapnic rat: a morphometric analysis. Q. J. Exp. Physiol. 69:1984;301-317.
14. + currents in pulmonary airway sensors show altered responses in mice with NADPH oxidase deficiency. Arch. Anat. Cytol. Path. Clin. Exp. Path. 46:1998;558.
15. Fu X.W., Nurse C.A., Wang Y.T., Cutz E. Selective modulation of membrane currents by hypoxia in intact airway chemoreceptors from neonatal rabbit. J. Physiol. Lond. 514:1999;139-150.
16. 2 tension. Proc. Natl. Acad. Sci. USA. 88:1991;2927-2930.
17. Ganfornina M.D., López-Barneo J. Potassium channel types in arterial chemoreceptors and their selective modulation by oxygen. J. Gen. Physiol. 100:1992;401-426.
18. González C., Almaraz L., Obeso A., Rigual R. Oxygen and acid chemoreception in the carotid body chemoreceptors. TINS. 15:1992;146-153.
19. González C., Almaraz L., Obeso A., Rigual R. Carotid body chemoreceptors: from natural stimuli to sensory discharges. Physiol. Rev. 74:1994;829-898.
20. Hoyt R.F. Jr., Sorokin S.P., Feldman H. Small-granule (neuro)endocrine cells in the infracardiac lobe of a hamster lung: number, subtypes, and distribution. Exp. Lung Res. 3:1982;273-298.
21. Johnson, D.E., Kulik, T.J., Lock, J.E., Elde, R.P., Thompson T.R., 1985. Bombesin-, calcitonin- and serotonin-immunoreactive pulmonary neuroendocrine cells in acute and chronic neonatal lung disease. Pediatr. Pulmonol. 1 (Suppl.), S13-S20.
22. Johnson D.E., Georgieff M.K. Pulmonary neuroendocrine cells: their secretory products and their potential roles in health and chronic lung disease in infancy. Am. Rev. Respir. Dis. 143:1989;815-819.
23. Kummer W., Acker H. Immunohistochemical demonstration of four subunits of neutrophil NAD(P)H oxidase in type I cells of carotid body. J. Appl. Physiol. 78:1995;1904-1909.
24. Lauweryns J.M., Cokelaere M. Hypoxia-sensitive neuro-epithelial bodies: intrapulmonary secretory neuroreceptors modulated by the CNS. Z. Zellforsch. Milrosk. Anat. 145:1973;521-540.
25. Lauweryns J.M., Cokelaere M., Deleersnyder M., Liebens M. Intrapulmonary neuroepithelial bodies in newborn rabbits. Influence of hypoxia, hypercapnia, nicotine, reserpine, L-dopa and 5-HT. Cell Tissue Res. 182:1977;425-440.
26. Lauweryns J.M., Cokelaere M., Lerut T., Theunynck P. Cross-circulation studies on the influence of hypoxia and hypoxaemia on neuroepithelial bodies in young rabbits. Cell Tissue Res. 193:1978;373-386.
27. Lauweryns J.M., Van Lommel A. Morphometric analysis of hypoxia-induced synaptic activity in intrapulmonary neuroepithelial bodies. Cell Tissue Res. 226:1982;201-214.
28. Lauweryns J.M., Van Lommel A., Dom R.J. Innervation of rabbit intrapulmonary neuroepithelial bodies. Quantitative and qualitative ultrastructural study after vagotomy. J. Neurol. Sci. 67:1985;81-92.
29. Lauweryns J.M., Van Lommel A. Effects of various vagotomy procedures on the reaction to hypoxia of rabbit neuroepithelial bodies: modulation by intrapulmonary axon reflexes? Exp. Lung Res. 11:1986;319-339.
30. Lauweryns J.M., De Bock V., Decramer M. Effects of unilateral vagal stimulation on intrapulmonary neuroepithelial bodies. J. Appl. Physiol. 63:1987;1781-1787.
31. Lauweryns J.M., Tierens A., Decramer M. Influence of hypercapnia on rabbit intrapulmonary neuroepithelial bodies: microfluorometric and morphometric study. Eur. Respir. J. 3:1990;182-186.
32. 2 in type I chemoreceptor cells. Science. 241:1988;580-582.
33. López-Barneo J. Oxygen-sensing by ion channels and the regulation of cellular functions. Trends Neurosci. 19:1996;435-440.
34. McDonald D.M. Peripheral chemoreceptors: structure-function relationships of the carotid body. Hornbein T.F. Regulation of Breathing, Part 1. 1981;105-319 Dekker, New York.
35. McGregor K.H., Gil J., Lahiri S. A morphometric study of the carotid body in chronically hypoxic rats. J. Appl. Physiol. 57:1988;1430-1438.
36. + channels in neuroepithelial body-derived small cell carcinoma cells of the human lung. Am. J. Physiol. 275:1998;L709-L716.
37. Pack R.J., Barker S., Howe A. The effects of hypoxia on the number of amine-containing cells in the lung of the adult rat. Eur. J. Respir. Dis. 68:1986;121-130.
38. Parkins K.J., Poets C.F., O'Brien L.M., Stebbens V.A., Southall D.P. Effect of exposure to 15% oxygen on breathing patterns and oxygen saturation in infants: interventional study. Br. Med. J. 316:1998;887-891.
39. Pearse A.G.E., Polak J.M., Rost F.W.D., Fontaine J., Le Lievre C., Le Douarin N. Demonstration of the neural crest origin of type I (APUD) cells in avian carotid body, using a cytochemical marker system. Histochemie. 34:1973;191-203.
40. Peers C. Oxygen-sensitive ion channels. Trends Pharmacol. Sci. 18:1997;405-408.
41. Perrin D.G., Cutz E., Becker L.E., Bryan A.C., Madapallimatum A., Sole M.J. Sudden infant death syndrome: increased carotid body dopamine and noradrenaline contents. Lancet. 2:1984;535-537.
42. Perrin D.G., MacDonald T.J., Cutz E. Hyperplasia of bombesin-immunoreactive pulmonary neuroendocrine cells and neuroepithelial bodies in sudden infant death syndrome. Pediatr. Pathol. 11:1991;431-447.
43. Pollack J.D., Williams D.A., Gifford M.A.C. et al. Mouse model of X-linked chronic granulomatous disease, an inherited defect in phagocyte superoxide production. Nat. Genet. 9:1995;202-209.
44. Remmers J.E., Lahiri S. Regulating the ventilatory pump: a splendid control system prone to fail during sleep. Am. J. Respir. Crit. Care Med. 157:1998;S95-S100.
45. Ruppersberg J.P., Stocker M., Pongs O., Heinemann S.H., Frank R., Koenen M. Regulation of fast inactivation of cloned mammalian IK(A) channels by cysteine oxidation. Nature. 352:1991;711-714.
46. Sorokin S.P., Hoyt R.F. Jr. Neuroepithelial bodies and solitary small-granule endocrine cells. Massaro D. Lung Cell Biology. 1989;191-344 Marcel Dekker, New York.
47. Sorokin S.P., Hoyt R.F. Jr. On the supposed function of neuroepithelial bodies in adult mammalian lungs. NIPS. 5:1990;89-95.
48. Sorokin S.P., Hoyt R.F. Jr., Shaffer M.J. Ontogeny of neuroepithelial bodies: correlations with mitogenesis and innervation. Microsc. Res. Tech. 37:1997;43-61.
49. + channels by hydrogen peroxide. Biochem. Biophys. Res. Commun. 186:1992;1681-1687.
50. + channels in mammals. Peracchia C. Handbook of Membrane Channels. 1994;41-78 Academic, New York.
51. + channel may function as an oxygen sensor complex in airway chemoreceptors and small cell lung carcinoma cell lines. Proc. Natl. Acad. Sci. USA. 93:1996;13182-13187.
52. Weir E.K., Wyatt C.N., Reeve H.L., Huang J., Archer S.L., Peers C. Diphenyleneiodonium inhibits both potassium and calcium currents in isolated pulmonary artery smooth muscle cells. J. Appl. Physiol. 76:1994;2611-2615.
53. Weir E.K., Archer S.L. The mechanism of acute hypoxic pulmonary vasoconstriction: the tale of two channels. FASEB J. 9:1995;183-189.
54. 2+ currents in type I cells isolated from the neonatal rat carotid body. Neurosci. Lett. 172:1994;63-66.
55. Youngson C., Nurse C., Yeger H., Cutz E. Oxygen sensing in airway chemoreceptors. Nature. 365:1993;153-155.
56. 2-sensing protein (NADPH oxidase) in chemoreceptor cells. Microsc. Res. Tech. 37:1997a;101-106.
57. Youngson C., Nurse C., Wang D., Cutz E. Ionic currents and oxygen-sensing mechanism in neuroepithelial body cells. Cutz E. Cellular and Molecular Biology of Airway Chemoreceptors. 1997b;71-108 Landes Bioscience, Texas.