Synthesis, antileukemic and antiplatelet activities of 2,3-diaryl-6,7-dihydro-5H-1,4-diazepines

European Journal of Medicinal Chemistry

Volumn 43, Issue 9, 2008, Pages 2004-2010

  Ramajayam, R ^a   Giridhar, Rajani ^a   Yadav, M R ^a   Balaraman, R ^a   Djaballah, Hakim ^b   Shum, David ^b   Radu, Constantin ^b  

^a M S UNIVERSITY OF BARODA   (India)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Antileukemic; Antiplatelet activity; Diaryldiazepines

Indexed keywords

2 (2 CHLOROPHENYL) 3 (4' CHLOROROPHENYL) 6,7 DIHYDRO 5H 1,4 DIAZEPINE; 2 (4 CHLOROPHENYL) 3 (4' FLUOROPHENYL) 6,7 DIHYDRO 5H 1,4 DIAZEPINE; 6,7 DIHYDRO 5H 1,4 DIAZEPINE DERIVATIVE; ACETYLSALICYLIC ACID; ANTILEUKEMIC AGENT; ANTITHROMBOCYTIC AGENT; ARACHIDONIC ACID; DIAZEPINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; FEMALE; HUMAN; HUMAN CELL; IC 50; LEUKEMIA CELL LINE; NONHUMAN; RAT; REACTION ANALYSIS; THROMBOCYTE AGGREGATION INHIBITION;

ANIMALS; ANTINEOPLASTIC AGENTS; AZEPINES; CELL LINE, TUMOR; CELL PROLIFERATION; FEMALE; HUMANS; INHIBITORY CONCENTRATION 50; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; RATS;

EID: 50949086059     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2007.11.023     Document Type: Article

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