Design, synthesis, structure - Activity relationships, and molecular modeling studies of 2,3-diaryl-1,3-thiazolidin-4-ones as potent anti-HIV agents

Journal of Medicinal Chemistry

Volumn 45, Issue 24, 2002, Pages 5410-5413

  Barreca, Maria L ^a   Balzarini, Jan ^b   Chimirri, Alba ^a   De Clercq, Erik ^b   De Luca, Laura ^a   Höltje, Hans Dieter ^c   Höltje, Monika ^c   Monforte, Anna Maria ^a   Monforte, Pietro ^a   Pannecouque, Christophe ^b   Rao, Angela ^a   Zappalà, Maria ^b  

^a UNIVERSITY OF MESSINA   (Italy)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^c HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; DELAVIRDINE; EFAVIRENZ; LIGAND; NEVIRAPINE; NUCLEOSIDE; THIAZOLIDINE DERIVATIVE;

ANTIVIRAL ACTIVITY; ARTICLE; CALCULATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG DESIGN; DRUG EFFICACY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LIGAND BINDING; MOLECULAR MODEL; STRUCTURE ACTIVITY RELATION; VIRUS INHIBITION; VIRUS REPLICATION;

ANTI-HIV AGENTS; CELL LINE; DRUG DESIGN; HIV-1; HIV-1 REVERSE TRANSCRIPTASE; HUMANS; LIGANDS; MODELS, MOLECULAR; PROTEIN BINDING; REVERSE TRANSCRIPTASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES; VIRUS REPLICATION;

EID: 0037153210     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm020977+     Document Type: Article

References (11)

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