Studies in 3,4-diaryl-1,2,5-oxadiazoles and their N-oxides: Search for better COX-2 inhibitors

Acta Pharmaceutica

Volumn 57, Issue 1, 2007, Pages 13-30

  Yadav, Mange Ram ^a   Shirude, Shrikant T ^a   Puntambekar, Devendra S ^a   Patel, Pinkal J ^a   Prajapati, Hetal B ^a   Parmar, Arvind ^a   Balaraman, R ^a   Giridhar, Rajani ^a  

^a M S UNIVERSITY OF BARODA   (India)

Author keywords

1,2,5 oxadiazole; 1,2,5 oxadiazole N oxide; COX 2 inhibitor

Indexed keywords

3,4 DI(4 METHOXYPHENYL) 1,2,5 OXADIAZOLE N OXIDE; 3,4 DIARY 1,2,5 OXADIAZOLE; 3,4 DIARY 1,2,5 OXADIAZOLE N OXIDE; CELECOXIB; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; OXADIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG INHIBITION; DRUG MECHANISM; DRUG PROTEIN BINDING; DRUG SYNTHESIS; ENZYME INHIBITION; HYDROGEN BOND; IN VITRO STUDY; IN VIVO STUDY; MALE; MOLECULAR MODEL; NONHUMAN; PAW EDEMA; RAT;

ANIMALS; CARRAGEENAN; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; EDEMA; FOOT; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MODELS, MOLECULAR; OXADIAZOLES; OXIDES; RATS; RATS, SPRAGUE-DAWLEY; SPECTROPHOTOMETRY, INFRARED; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

EID: 33847644608     PISSN: 13300075     EISSN: None     Source Type: Journal    
DOI: 10.2478/v10007-007-0002-z     Document Type: Article

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