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Volumn 144, Issue 1, 2008, Pages 39-46

Obesity, inflammation and diabetes;Obesidad, inflamación y diabetes

Author keywords

Diabetes; Inflammation; Insulin resistance; Obesity; Stress

Indexed keywords

CYTOKINE; INSULIN; LIPID; PROTEIN KINASE C; STRESS ACTIVATED PROTEIN KINASE;

EID: 50849126079     PISSN: 00163813     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (10)

References (40)
  • 1
    • 3042606551 scopus 로고    scopus 로고
    • Effects of infecction and inflammation on lipid and lipoprotein metabolism: Mechanisms and consequences to the host [review]
    • Khovidhunkit W, Dunchateau PN, Medzihraszk KF, Moser AH, Naya-Vigne J, Shigenaga JK, et al. Effects of infecction and inflammation on lipid and lipoprotein metabolism: mechanisms and consequences to the host [review]. J Lipid Res 2004;45:1169-1196.
    • (2004) J Lipid Res , vol.45 , pp. 1169-1196
    • Khovidhunkit, W.1    Dunchateau, P.N.2    Medzihraszk, K.F.3    Moser, A.H.4    Naya-Vigne, J.5    Shigenaga, J.K.6
  • 2
    • 0027459878 scopus 로고
    • Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance
    • Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science 1993;259:87-91.
    • (1993) Science , vol.259 , pp. 87-91
    • Hotamisligil, G.S.1    Shargill, N.S.2    Spiegelman, B.M.3
  • 3
    • 0028931724 scopus 로고
    • Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance
    • Hotamisligil GS, Arner P, Caro JF, Atkinson RL, Spiegelman BM. Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. J Clin Invest 1995;95:2409-2415.
    • (1995) J Clin Invest , vol.95 , pp. 2409-2415
    • Hotamisligil, G.S.1    Arner, P.2    Caro, J.F.3    Atkinson, R.L.4    Spiegelman, B.M.5
  • 4
    • 0028968879 scopus 로고
    • The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase
    • Kern PA, Saghizadeh M, Ong JM, Bosch RJ, Deem R, Simsolo RB. The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase. J Clin Invest 1995;95:2111-2119.
    • (1995) J Clin Invest , vol.95 , pp. 2111-2119
    • Kern, P.A.1    Saghizadeh, M.2    Ong, J.M.3    Bosch, R.J.4    Deem, R.5    Simsolo, R.B.6
  • 5
    • 0030756346 scopus 로고    scopus 로고
    • Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function
    • Uysal KT, Wiesbrock SM, Marino MW, Hotamisligil GS. Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function. Nature 1997;389:610-614.
    • (1997) Nature , vol.389 , pp. 610-614
    • Uysal, K.T.1    Wiesbrock, S.M.2    Marino, M.W.3    Hotamisligil, G.S.4
  • 6
    • 0033562455 scopus 로고    scopus 로고
    • Markers of inflammation and prediction of diabetes mellitus in adults (atherosclerosis risk in communities study): A cohort study
    • Shmidt MI. Markers of inflammation and prediction of diabetes mellitus in adults (atherosclerosis risk in communities study): a cohort study. Lancet 1999;353:1649-1652
    • (1999) Lancet , vol.353 , pp. 1649-1652
    • Shmidt, M.I.1
  • 7
    • 0036312978 scopus 로고    scopus 로고
    • C-reactive protein is an independent predictor of risk for the development of diabetes in the West of Scotland Coronary Prevention Study
    • Freeman DJ, Norrie J, Caslake MJ, Gaw A, Ford I, Lowe GD, et al. C-reactive protein is an independent predictor of risk for the development of diabetes in the West of Scotland Coronary Prevention Study. Diabetes 2002;51:1596-1600.
    • (2002) Diabetes , vol.51 , pp. 1596-1600
    • Freeman, D.J.1    Norrie, J.2    Caslake, M.J.3    Gaw, A.4    Ford, I.5    Lowe, G.D.6
  • 8
    • 1442275317 scopus 로고    scopus 로고
    • Inflammation and activated innate immunity in the pathogenesis of type diabetes
    • Pickup JC. Inflammation and activated innate immunity in the pathogenesis of type diabetes. Diabetes Care 2004;27:813-823.
    • (2004) Diabetes Care , vol.27 , pp. 813-823
    • Pickup, J.C.1
  • 9
    • 0348222671 scopus 로고    scopus 로고
    • Inflamation: The link between insulin resistance, obesity and diabetes
    • Dandona P, Aljada A, Bandyopadhay A. Inflamation: the link between insulin resistance, obesity and diabetes. Trends Immunol 2004;25:4-7.
    • (2004) Trends Immunol , vol.25 , pp. 4-7
    • Dandona, P.1    Aljada, A.2    Bandyopadhay, A.3
  • 10
    • 0032572722 scopus 로고    scopus 로고
    • Leptin modulates the T-cell immune response and reverses starvation-induced immunosupression
    • Lord GM, Matarese G, Howard JK, Baker RJ, Bloom SR, Lechler RI. Leptin modulates the T-cell immune response and reverses starvation-induced immunosupression. Nature 1998;394:897-901
    • (1998) Nature , vol.394 , pp. 897-901
    • Lord, G.M.1    Matarese, G.2    Howard, J.K.3    Baker, R.J.4    Bloom, S.R.5    Lechler, R.I.6
  • 11
    • 19944433652 scopus 로고    scopus 로고
    • Visfatin: A protein secreted by visceral fat that mimics the effects of insulin
    • Fukuhara, A, Matsuda M, Nishizawa M, Segawa K, Tanaka M, Kishimoto K, et al. Visfatin: a protein secreted by visceral fat that mimics the effects of insulin. Science 2005;307:426-430.
    • (2005) Science , vol.307 , pp. 426-430
    • Fukuhara, A.1    Matsuda, M.2    Nishizawa, M.3    Segawa, K.4    Tanaka, M.5    Kishimoto, K.6
  • 12
    • 24144498663 scopus 로고    scopus 로고
    • Distribution and determinants of adiponectin, resistin and ghrelin in a randomly selected healthy population
    • Vilarrasa N, Vendrell J, Maravall J, Broch M, Estepa A, Megia A, et al. Distribution and determinants of adiponectin, resistin and ghrelin in a randomly selected healthy population. Clinical Endocrionology 2005;63:329-335.
    • (2005) Clinical Endocrionology , vol.63 , pp. 329-335
    • Vilarrasa, N.1    Vendrell, J.2    Maravall, J.3    Broch, M.4    Estepa, A.5    Megia, A.6
  • 13
    • 1842506529 scopus 로고    scopus 로고
    • The current biology of resistin
    • Steppan CM, Lazar MA. The current biology of resistin. J Intern Med 2004;255:439-447.
    • (2004) J Intern Med , vol.255 , pp. 439-447
    • Steppan, C.M.1    Lazar, M.A.2
  • 14
    • 0035464206 scopus 로고    scopus 로고
    • Adipocyte produces matrix metalloproteinases 2 and 9:involvement in adipose differentiation
    • Bouloumie A, Senegenés C, Portolan G, Galitzky J, Lafontan M. Adipocyte produces matrix metalloproteinases 2 and 9:involvement in adipose differentiation. Diabetes 2001;50:2080-2086.
    • (2001) Diabetes , vol.50 , pp. 2080-2086
    • Bouloumie, A.1    Senegenés, C.2    Portolan, G.3    Galitzky, J.4    Lafontan, M.5
  • 17
    • 0030748457 scopus 로고    scopus 로고
    • The insulin signalling system and the IRS proteins
    • White MF. The insulin signalling system and the IRS proteins. Diabetologia 1997;40(Suppl. 2):S2-S17.
    • (1997) Diabetologia , vol.40 , Issue.SUPPL. 2
    • White, M.F.1
  • 18
    • 0030061922 scopus 로고    scopus 로고
    • Hotamisligil GS, Peraldi P, Budavari A, Ellis R, White MF, Spiegelman BM. IRS-1-mediated inhibición of insulin receptor tyrosine kinase activity in TNF-alpha-and obesity-induced insulin resistance. Science 1996;271:665-668.
    • Hotamisligil GS, Peraldi P, Budavari A, Ellis R, White MF, Spiegelman BM. IRS-1-mediated inhibición of insulin receptor tyrosine kinase activity in TNF-alpha-and obesity-induced insulin resistance. Science 1996;271:665-668.
  • 19
    • 0034644522 scopus 로고    scopus 로고
    • Signal transduction by the JNK group of MAP kinases
    • Davis RJ. Signal transduction by the JNK group of MAP kinases. Cell 2000;103:239-252.
    • (2000) Cell , vol.103 , pp. 239-252
    • Davis, R.J.1
  • 20
    • 0037059330 scopus 로고    scopus 로고
    • Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action
    • Aguirre V, Werner ED, Giraud J, Lee YH, Shoelson SE, White MF. Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action. J Biol Chem 2002;277:1531-1537.
    • (2002) J Biol Chem , vol.277 , pp. 1531-1537
    • Aguirre, V.1    Werner, E.D.2    Giraud, J.3    Lee, Y.H.4    Shoelson, S.E.5    White, M.F.6
  • 22
    • 0030669392 scopus 로고    scopus 로고
    • A molecular basis for insulin resistance. Elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtamembrane region of the insulina receptor and impairs their ability to undergo insulin-induced tyrosine phosphorylation
    • Paz K, Hemi R, LeRoith D, Karasik A, Elhanany E, Kanety H, et al. A molecular basis for insulin resistance. Elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtamembrane region of the insulina receptor and impairs their ability to undergo insulin-induced tyrosine phosphorylation. J Biol Chem 1997;272:29911-29918.
    • (1997) J Biol Chem , vol.272 , pp. 29911-29918
    • Paz, K.1    Hemi, R.2    LeRoith, D.3    Karasik, A.4    Elhanany, E.5    Kanety, H.6
  • 24
    • 0037184925 scopus 로고    scopus 로고
    • Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle
    • Yu C, Chen Y, Cline GW, Zhang D, Zong H, Wang Y. Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle. J Biol Chem 2002;277:50230-50236.
    • (2002) J Biol Chem , vol.277 , pp. 50230-50236
    • Yu, C.1    Chen, Y.2    Cline, G.W.3    Zhang, D.4    Zong, H.5    Wang, Y.6
  • 25
    • 20044376702 scopus 로고    scopus 로고
    • Banting Lecture 2004. The Pathobiology of Diabetic Complications. A Unifying Mechanism
    • Brownlee M. Banting Lecture 2004. The Pathobiology of Diabetic Complications. A Unifying Mechanism. Diabetes 2005;54:1615-1625.
    • (2005) Diabetes , vol.54 , pp. 1615-1625
    • Brownlee, M.1
  • 27
    • 0346250165 scopus 로고    scopus 로고
    • Cellular mechanism of insulin resistance: Potential links with inflammation
    • Perseghin, G, Petersen K, Shulman GI. Cellular mechanism of insulin resistance: potential links with inflammation. Int J Obes Relat Metab Disord 2003;27(Suppl 3):S6-S11.
    • (2003) Int J Obes Relat Metab Disord , vol.27 , Issue.SUPPL. 3
    • Perseghin, G.1    Petersen, K.2    Shulman, G.I.3
  • 28
    • 0036830636 scopus 로고    scopus 로고
    • SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2
    • Rui L, Yuan M, Frantz D, Shoelson S, White MF. SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2. J Biol Chem 2002;277:42394-42398.
    • (2002) J Biol Chem , vol.277 , pp. 42394-42398
    • Rui, L.1    Yuan, M.2    Frantz, D.3    Shoelson, S.4    White, M.F.5
  • 29
    • 0035854723 scopus 로고    scopus 로고
    • Suppressors of cytokine signaling-1 and -6 associate with and inhibit the insulin receptor. A potential mechanism for cytokine-mediated insulin resistance
    • Mooney, RA, Senn J, Cameron S, Inamdar N, Boivin LM, Shang Y, et al. Suppressors of cytokine signaling-1 and -6 associate with and inhibit the insulin receptor. A potential mechanism for cytokine-mediated insulin resistance. J Biol Chem 2001;276:25889-25893.
    • (2001) J Biol Chem , vol.276 , pp. 25889-25893
    • Mooney, R.A.1    Senn, J.2    Cameron, S.3    Inamdar, N.4    Boivin, L.M.5    Shang, Y.6
  • 30
    • 0030852877 scopus 로고    scopus 로고
    • Role of nitric oxide in obesity-induced beta cell disease
    • Shimabukuro M, Koyama K, Lee Y, Unger RH. Role of nitric oxide in obesity-induced beta cell disease. J Clin Invest 1997;100:290-295
    • (1997) J Clin Invest , vol.100 , pp. 290-295
    • Shimabukuro, M.1    Koyama, K.2    Lee, Y.3    Unger, R.H.4
  • 31
    • 0034770292 scopus 로고    scopus 로고
    • Targeted disruption of inducible nitric oxide synthase protects against obesity-linked insulin resistance in muscle
    • Perreault M, Marette A. Targeted disruption of inducible nitric oxide synthase protects against obesity-linked insulin resistance in muscle. Nat Med 2001;7:1138-1143
    • (2001) Nat Med , vol.7 , pp. 1138-1143
    • Perreault, M.1    Marette, A.2
  • 33
    • 11144356074 scopus 로고    scopus 로고
    • Activated liver X receptors stimulate adipocyte differentiation through induction of peroxisome proliferator-activated receptor gamma expression
    • Seo JB. Activated liver X receptors stimulate adipocyte differentiation through induction of peroxisome proliferator-activated receptor gamma expression. Mol Cell Biol 2004;24:3430-3444.
    • (2004) Mol Cell Biol , vol.24 , pp. 3430-3444
    • Seo, J.B.1
  • 34
    • 33644866796 scopus 로고    scopus 로고
    • Receptor Activation and high-density lipoproteína biology. A reversal of fortune?
    • Lee C, Plutzky J. Liver X Receptor Activation and high-density lipoproteína biology. A reversal of fortune? Circulation 2006;113:5-8.
    • (2006) Circulation , vol.113 , pp. 5-8
    • Lee, C.1    Plutzky, J.2    Liver, X.3
  • 35
    • 0031888958 scopus 로고    scopus 로고
    • PPARgamma agonists inhibit production of monocyte inflammatory cytokines
    • Jiang C, Ting AT, Seed B. PPARgamma agonists inhibit production of monocyte inflammatory cytokines. Nature 1998;391:82-86.
    • (1998) Nature , vol.391 , pp. 82-86
    • Jiang, C.1    Ting, A.T.2    Seed, B.3
  • 36
    • 5644231992 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
    • Özcan U, Cao Q, Yilmaz E, Lee AH, Iwakoshi NN, Özdelen E, et al. Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science 2004;306:457-461.
    • (2004) Science , vol.306 , pp. 457-461
    • Özcan, U.1    Cao, Q.2    Yilmaz, E.3    Lee, A.H.4    Iwakoshi, N.N.5    Özdelen, E.6
  • 38
    • 14644397903 scopus 로고    scopus 로고
    • The endoplasmic reticulum chaperone improves insulin resistance in type 2 diabetes
    • Ozawa K, Miyazaki M, Natsuhisa M, Takano K, Nakatani Y, Hatzaki M, et al. The endoplasmic reticulum chaperone improves insulin resistance in type 2 diabetes. Diabetes 2005;54:657-663.
    • (2005) Diabetes , vol.54 , pp. 657-663
    • Ozawa, K.1    Miyazaki, M.2    Natsuhisa, M.3    Takano, K.4    Nakatani, Y.5    Hatzaki, M.6
  • 39
    • 20044363264 scopus 로고    scopus 로고
    • The hyperglycemia-induced inflammatory response in adipocytes: The role of reactive oxygen species
    • Lin Y, Chen Y, Cline GW, Zhang D, Zong H, Wang Y, et al. The hyperglycemia-induced inflammatory response in adipocytes: the role of reactive oxygen species. J Biol Chem 2005;280:4617-4626.
    • (2005) J Biol Chem , vol.280 , pp. 4617-4626
    • Lin, Y.1    Chen, Y.2    Cline, G.W.3    Zhang, D.4    Zong, H.5    Wang, Y.6
  • 40
    • 12344305124 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and type 2 diabetes
    • Lowell BB, Shulman GI. Mitochondrial dysfunction and type 2 diabetes. Science 2005;307:384-387.
    • (2005) Science , vol.307 , pp. 384-387
    • Lowell, B.B.1    Shulman, G.I.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.