메뉴 건너뛰기




Volumn 375, Issue 3, 2008, Pages 399-404

Temperature sensitivity of phospho-Ser473-PKB/AKT

Author keywords

Ionizing radiation; p Ser473 PKB Akt; PDK2; Phosphorylation; PP2A; Stability; Temperature sensitivity

Indexed keywords

PHOSPHATASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; SERINE DERIVATIVE;

EID: 50849103001     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.08.035     Document Type: Article
Times cited : (18)

References (41)
  • 1
    • 42249098543 scopus 로고    scopus 로고
    • Oncogenic signaling of class I PI3K isoforms
    • Denley A., Kang S., Karst U., and Vogt P.K. Oncogenic signaling of class I PI3K isoforms. Oncogene 27 (2008) 2561-2574
    • (2008) Oncogene , vol.27 , pp. 2561-2574
    • Denley, A.1    Kang, S.2    Karst, U.3    Vogt, P.K.4
  • 2
    • 31944448780 scopus 로고    scopus 로고
    • Oncogenic transformation induced by the p110beta, -gamma, and -delta isoforms of class I phosphoinositide 3-kinase
    • Kang S., Denley A., Vanhaesebroeck B., and Vogt P.K. Oncogenic transformation induced by the p110beta, -gamma, and -delta isoforms of class I phosphoinositide 3-kinase. Proc. Natl. Acad. Sci. USA 103 (2006) 1289-1294
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 1289-1294
    • Kang, S.1    Denley, A.2    Vanhaesebroeck, B.3    Vogt, P.K.4
  • 3
    • 33750285711 scopus 로고    scopus 로고
    • Role of PI3K and AKT specific isoforms in ovarian cancer cell migration, invasion and proliferation through the p70S6K1 pathway
    • Meng Q., Xia C., Fang J., Rojanasakul Y., and Jiang B.H. Role of PI3K and AKT specific isoforms in ovarian cancer cell migration, invasion and proliferation through the p70S6K1 pathway. Cell Signal. 18 (2006) 2262-2271
    • (2006) Cell Signal. , vol.18 , pp. 2262-2271
    • Meng, Q.1    Xia, C.2    Fang, J.3    Rojanasakul, Y.4    Jiang, B.H.5
  • 5
    • 0032534025 scopus 로고    scopus 로고
    • The presence of a constitutively active phosphoinositide 3-kinase in small cell lung cancer cells mediates anchorage-independent proliferation via a protein kinase B and p70s6k-dependent pathway
    • Moore S.M., Rintoul R.C., Walker T.R., Chilvers E.R., Haslett C., and Sethi T. The presence of a constitutively active phosphoinositide 3-kinase in small cell lung cancer cells mediates anchorage-independent proliferation via a protein kinase B and p70s6k-dependent pathway. Cancer Res. 58 (1998) 5239-5247
    • (1998) Cancer Res. , vol.58 , pp. 5239-5247
    • Moore, S.M.1    Rintoul, R.C.2    Walker, T.R.3    Chilvers, E.R.4    Haslett, C.5    Sethi, T.6
  • 9
    • 0034745353 scopus 로고    scopus 로고
    • Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells
    • Zhou B.P., Liao Y., Xia W., Spohn B., Lee M.H., and Hung M.C. Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells. Nat. Cell Biol. 3 (2001) 245-252
    • (2001) Nat. Cell Biol. , vol.3 , pp. 245-252
    • Zhou, B.P.1    Liao, Y.2    Xia, W.3    Spohn, B.4    Lee, M.H.5    Hung, M.C.6
  • 11
    • 0037205048 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase pathway
    • Cantley L.C. The phosphoinositide 3-kinase pathway. Science 296 (2002) 1655-1657
    • (2002) Science , vol.296 , pp. 1655-1657
    • Cantley, L.C.1
  • 12
    • 0033564514 scopus 로고    scopus 로고
    • The phosphatidylinositol 3′-kinase pathway is a dominant growth factor-activated cell survival pathway in LNCaP human prostate carcinoma cells
    • Lin J., Adam R.M., Santiestevan E., and Freeman M.R. The phosphatidylinositol 3′-kinase pathway is a dominant growth factor-activated cell survival pathway in LNCaP human prostate carcinoma cells. Cancer Res. 59 (1999) 2891-2897
    • (1999) Cancer Res. , vol.59 , pp. 2891-2897
    • Lin, J.1    Adam, R.M.2    Santiestevan, E.3    Freeman, M.R.4
  • 13
    • 0030702123 scopus 로고    scopus 로고
    • Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
    • Datta S.R., Dudek H., Tao X., Masters S., Fu H., Gotoh Y., and Greenberg M.E. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 91 (1997) 231-241
    • (1997) Cell , vol.91 , pp. 231-241
    • Datta, S.R.1    Dudek, H.2    Tao, X.3    Masters, S.4    Fu, H.5    Gotoh, Y.6    Greenberg, M.E.7
  • 15
    • 0035949588 scopus 로고    scopus 로고
    • A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus
    • Mayo L.D., and Donner D.B. A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus. Proc. Natl. Acad. Sci. USA 98 (2001) 11598-11603
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 11598-11603
    • Mayo, L.D.1    Donner, D.B.2
  • 17
    • 0029587224 scopus 로고
    • Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
    • Cross D.A., Alessi D.R., Cohen P., Andjelkovich M., and Hemmings B.A. Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 378 (1995) 785-789
    • (1995) Nature , vol.378 , pp. 785-789
    • Cross, D.A.1    Alessi, D.R.2    Cohen, P.3    Andjelkovich, M.4    Hemmings, B.A.5
  • 18
    • 36849032852 scopus 로고    scopus 로고
    • Radiation-induced EGFR-signaling and control of DNA-damage repair
    • Rodemann H.P., Dittmann K., and Toulany M. Radiation-induced EGFR-signaling and control of DNA-damage repair. Int. J. Radiat. Biol. 83 (2007) 781-791
    • (2007) Int. J. Radiat. Biol. , vol.83 , pp. 781-791
    • Rodemann, H.P.1    Dittmann, K.2    Toulany, M.3
  • 19
    • 40749094856 scopus 로고    scopus 로고
    • Activation of the PI3-K/AKT pathway and implications for radioresistance mechanisms in head and neck cancer
    • Bussink J., van der Kogel A.J., and Kaanders J.H. Activation of the PI3-K/AKT pathway and implications for radioresistance mechanisms in head and neck cancer. Lancet Oncol. 9 (2008) 288-296
    • (2008) Lancet Oncol. , vol.9 , pp. 288-296
    • Bussink, J.1    van der Kogel, A.J.2    Kaanders, J.H.3
  • 20
    • 34548058584 scopus 로고    scopus 로고
    • Stimulated PI3K-AKT signaling mediated through ligand or radiation-induced EGFR depends indirectly, but not directly, on constitutive K-Ras activity
    • Toulany M., Baumann M., and Rodemann H.P. Stimulated PI3K-AKT signaling mediated through ligand or radiation-induced EGFR depends indirectly, but not directly, on constitutive K-Ras activity. Mol. Cancer Res. 5 (2007) 863-872
    • (2007) Mol. Cancer Res. , vol.5 , pp. 863-872
    • Toulany, M.1    Baumann, M.2    Rodemann, H.P.3
  • 22
    • 0032497832 scopus 로고    scopus 로고
    • Structure and function of phosphoinositide 3-kinases
    • Wymann M.P., and Pirola L. Structure and function of phosphoinositide 3-kinases. Biochim. Biophys. Acta 1436 (1998) 127-150
    • (1998) Biochim. Biophys. Acta , vol.1436 , pp. 127-150
    • Wymann, M.P.1    Pirola, L.2
  • 25
    • 0034653608 scopus 로고    scopus 로고
    • The PI3K-PDK1 connection: more than just a road to PKB
    • Vanhaesebroeck B., and Alessi D.R. The PI3K-PDK1 connection: more than just a road to PKB. Biochem. J. 346 Pt 3 (2000) 561-576
    • (2000) Biochem. J. , vol.346 , Issue.PART 3 , pp. 561-576
    • Vanhaesebroeck, B.1    Alessi, D.R.2
  • 26
    • 35148860779 scopus 로고    scopus 로고
    • Nuclear phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3-kinase, Akt, and PTen: emerging key regulators of anti-apoptotic signaling and carcinogenesis
    • Martelli A.M., Cocco L., Capitani S., Miscia S., Papa S., and Manzoli F.A. Nuclear phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3-kinase, Akt, and PTen: emerging key regulators of anti-apoptotic signaling and carcinogenesis. Eur. J. Histochem. 51 Suppl 1 (2007) 125-131
    • (2007) Eur. J. Histochem. , vol.51 , Issue.SUPPL. 1 , pp. 125-131
    • Martelli, A.M.1    Cocco, L.2    Capitani, S.3    Miscia, S.4    Papa, S.5    Manzoli, F.A.6
  • 27
    • 1842852634 scopus 로고    scopus 로고
    • Pharmacogenomic profiling of the PI3K/PTEN-AKT-mTOR pathway in common human tumors
    • Xu G., Zhang W., Bertram P., Zheng X.F., and McLeod H. Pharmacogenomic profiling of the PI3K/PTEN-AKT-mTOR pathway in common human tumors. Int. J. Oncol. 24 (2004) 893-900
    • (2004) Int. J. Oncol. , vol.24 , pp. 893-900
    • Xu, G.1    Zhang, W.2    Bertram, P.3    Zheng, X.F.4    McLeod, H.5
  • 28
    • 50849091879 scopus 로고    scopus 로고
    • Available from: .
    • Available from: .
  • 30
    • 0026792844 scopus 로고
    • Estimation of the rate constants associated with the inhibitory effect of okadaic acid on type 2A protein phosphatase by time-course analysis
    • Takai A., Ohno Y., Yasumoto T., and Mieskes G. Estimation of the rate constants associated with the inhibitory effect of okadaic acid on type 2A protein phosphatase by time-course analysis. Biochem. J. 287 Pt 1 (1992) 101-106
    • (1992) Biochem. J. , vol.287 , Issue.PART 1 , pp. 101-106
    • Takai, A.1    Ohno, Y.2    Yasumoto, T.3    Mieskes, G.4
  • 31
    • 37649024728 scopus 로고    scopus 로고
    • Protein phosphatase 2A regulates life and death decisions via Akt in a context-dependent manner
    • Andrabi S., Gjoerup O.V., Kean J.A., Roberts T.M., and Schaffhausen B. Protein phosphatase 2A regulates life and death decisions via Akt in a context-dependent manner. Proc. Natl. Acad. Sci. USA 104 (2007) 19011-19016
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 19011-19016
    • Andrabi, S.1    Gjoerup, O.V.2    Kean, J.A.3    Roberts, T.M.4    Schaffhausen, B.5
  • 32
    • 2942726061 scopus 로고    scopus 로고
    • Akt phosphorylation and kinase activity are down-regulated during hibernation in the 13-lined ground squirrel
    • Cai D., McCarron R.M., Yu E.Z., Li Y., and Hallenbeck J. Akt phosphorylation and kinase activity are down-regulated during hibernation in the 13-lined ground squirrel. Brain Res. 1014 (2004) 14-21
    • (2004) Brain Res. , vol.1014 , pp. 14-21
    • Cai, D.1    McCarron, R.M.2    Yu, E.Z.3    Li, Y.4    Hallenbeck, J.5
  • 33
    • 0035851041 scopus 로고    scopus 로고
    • Effects of hypothermia on neonatal hypoxic-ischemic brain injury in the rat: phosphorylation of Akt, activation of caspase-3-like protease
    • Tomimatsu T., Fukuda H., Endo M., Watanabe N., Mu J., Kohzuki M., Fujii E., Kanzaki T., and Murata Y. Effects of hypothermia on neonatal hypoxic-ischemic brain injury in the rat: phosphorylation of Akt, activation of caspase-3-like protease. Neurosci. Lett. 312 (2001) 21-24
    • (2001) Neurosci. Lett. , vol.312 , pp. 21-24
    • Tomimatsu, T.1    Fukuda, H.2    Endo, M.3    Watanabe, N.4    Mu, J.5    Kohzuki, M.6    Fujii, E.7    Kanzaki, T.8    Murata, Y.9
  • 35
    • 0642303588 scopus 로고
    • Nerve growth factor induces protein-tyrosine phosphorylation
    • Maher P.A. Nerve growth factor induces protein-tyrosine phosphorylation. Proc. Natl. Acad. Sci. USA 85 (1988) 6788-6791
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 6788-6791
    • Maher, P.A.1
  • 36
    • 17044370905 scopus 로고    scopus 로고
    • Crystal structure of cold-active protein-tyrosine phosphatase from a psychrophile, Shewanella sp.
    • Tsuruta H., Mikami B., and Aizono Y. Crystal structure of cold-active protein-tyrosine phosphatase from a psychrophile, Shewanella sp. J. Biochem. (Tokyo) 137 (2005) 69-77
    • (2005) J. Biochem. (Tokyo) , vol.137 , pp. 69-77
    • Tsuruta, H.1    Mikami, B.2    Aizono, Y.3
  • 37
    • 0030844357 scopus 로고    scopus 로고
    • Low temperature perception in plants: effects of cold on protein phosphorylation in cell-free extracts
    • Monroy A.F., Labbe E., and Dhindsa R.S. Low temperature perception in plants: effects of cold on protein phosphorylation in cell-free extracts. FEBS Lett. 410 (1997) 206-209
    • (1997) FEBS Lett. , vol.410 , pp. 206-209
    • Monroy, A.F.1    Labbe, E.2    Dhindsa, R.S.3
  • 38
    • 23044467856 scopus 로고    scopus 로고
    • PDK2: the missing piece in the receptor tyrosine kinase signaling pathway puzzle
    • Dong L.Q., and Liu F. PDK2: the missing piece in the receptor tyrosine kinase signaling pathway puzzle. Am. J. Physiol. Endocrinol. Metab. 289 (2005) E187-E196
    • (2005) Am. J. Physiol. Endocrinol. Metab. , vol.289
    • Dong, L.Q.1    Liu, F.2
  • 39
    • 0034718540 scopus 로고    scopus 로고
    • Modulation of Akt kinase activity by binding to Hsp90
    • Sato S., Fujita N., and Tsuruo T. Modulation of Akt kinase activity by binding to Hsp90. Proc. Natl. Acad. Sci. USA 97 (2000) 10832-10837
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 10832-10837
    • Sato, S.1    Fujita, N.2    Tsuruo, T.3
  • 40
    • 28844434558 scopus 로고    scopus 로고
    • mTOR.RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes
    • Hresko R.C., and Mueckler M. mTOR.RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes. J. Biol. Chem. 280 (2005) 40406-40416
    • (2005) J. Biol. Chem. , vol.280 , pp. 40406-40416
    • Hresko, R.C.1    Mueckler, M.2
  • 41
    • 33750044112 scopus 로고    scopus 로고
    • Stress and mTORture signaling
    • Reiling J.H., and Sabatini D.M. Stress and mTORture signaling. Oncogene 25 (2006) 6373-6383
    • (2006) Oncogene , vol.25 , pp. 6373-6383
    • Reiling, J.H.1    Sabatini, D.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.